Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARFGAP3 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Arfgap3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ARFGAP3 mRNA | CTD | PMID:36331819 | 1,1-dichloroethene | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of ARFGAP3 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | multiple interactions | ISO | Arfgap3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARFGAP3 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ARFGAP3 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of ARFGAP3 mRNA | CTD | PMID:32145629 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Arfgap3 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARFGAP3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARFGAP3 mRNA | CTD | PMID:24680724 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ARFGAP3 mRNA | CTD | PMID:24780913 | aconitine | increases expression | EXP | | 6480464 | Aconitine results in increased expression of ARFGAP3 protein | CTD | PMID:33236894 | acrolein | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ARFGAP3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ARFGAP3 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases methylation | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ARFGAP3 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | ARFGAP3 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of ARFGAP3 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Tretinoin results in increased expression of ARFGAP3 mRNA | CTD | PMID:16604517 | alpha-pinene | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ARFGAP3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ARFGAP3 mRNA | CTD | PMID:32699268 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of ARFGAP3 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ARFGAP3 mRNA | CTD | PMID:33212167 | arsenous acid | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ARFGAP3 protein] | CTD | PMID:26598702 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of ARFGAP3 gene | CTD | PMID:28931070 | benzo[a]pyrene | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ARFGAP3 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ARFGAP3 protein | CTD | PMID:33278487 | benzo[a]pyrene | increases methylation | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ARFGAP3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ARFGAP3 mRNA | CTD | PMID:20127859 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARFGAP3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ARFGAP3 protein | CTD | PMID:34186270 | bisphenol A | decreases methylation | ISO | ARFGAP3 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ARFGAP3 gene | CTD | PMID:31601247 | bisphenol A | increases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ARFGAP3 protein | CTD | PMID:33376534 | bisphenol A | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [ginger extract results in increased abundance of Oils and Volatile] inhibits the reaction [bisphenol A results in increased expression of ARFGAP3 protein] | CTD | PMID:33376534 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ARFGAP3 mRNA | CTD | PMID:32145629 | caffeine | affects phosphorylation | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of ARFGAP3 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | cobalt dichloride | increases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of ARFGAP3 mRNA | CTD | PMID:19376846 | crocidolite asbestos | affects expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Asbestos and Crocidolite affects the expression of ARFGAP3 mRNA | CTD | PMID:24160326 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of ARFGAP3 mRNA | CTD | PMID:27523638 | cyclosporin A | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of ARFGAP3 mRNA | CTD | PMID:19770486 | cyclosporin A | increases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ARFGAP3 mRNA | CTD | PMID:20106945 more ... | diarsenic trioxide | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ARFGAP3 protein] | CTD | PMID:26598702 | disodium selenite | increases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of ARFGAP3 mRNA | CTD | PMID:18175754 | diuron | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Diuron results in decreased expression of ARFGAP3 mRNA | CTD | PMID:35967413 | dorsomorphin | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARFGAP3 mRNA | CTD | PMID:27188386 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of ARFGAP3 mRNA | CTD | PMID:29391264 | enzyme inhibitor | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ARFGAP3 protein | CTD | PMID:23301498 | epoxiconazole | decreases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of ARFGAP3 mRNA | CTD | PMID:35436446 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ARFGAP3 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Arfgap3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARFGAP3 mRNA | CTD | PMID:22206623 | FR900359 | decreases phosphorylation | ISO | ARFGAP3 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of ARFGAP3 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ARFGAP3 mRNA | CTD | PMID:33387578 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of ARFGAP3 mRNA | CTD | PMID:24136188 | isoflurane | increases methylation | ISO | Arfgap3 (Mus musculus) | 6480464 | Isoflurane results in increased methylation of ARFGAP3 mRNA | CTD | PMID:35249202 | ivermectin | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ARFGAP3 protein | CTD | PMID:32959892 | metformin | increases expression | EXP | | 6480464 | Metformin results in increased expression of ARFGAP3 mRNA | CTD | PMID:31324951 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ARFGAP3 gene | CTD | PMID:35440735 | ozone | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ARFGAP3 mRNA more ... | CTD | PMID:32699268 | paracetamol | multiple interactions | ISO | Arfgap3 (Mus musculus) | 6480464 | PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of ARFGAP3 mRNA] | CTD | PMID:29246445 | paracetamol | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of ARFGAP3 mRNA | CTD | PMID:29246445 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Arfgap3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ARFGAP3 mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of ARFGAP3 mRNA | CTD | PMID:19159669 | phenobarbital | decreases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of ARFGAP3 mRNA | CTD | PMID:19482888 | phenobarbital | multiple interactions | ISO | Arfgap3 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ARFGAP3 mRNA] | CTD | PMID:19482888 | pirinixic acid | multiple interactions | ISO | Arfgap3 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ARFGAP3 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ARFGAP3 mRNA | CTD | PMID:23811191 | propiconazole | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | propiconazole results in increased expression of ARFGAP3 mRNA | CTD | PMID:21278054 | quercetin | decreases phosphorylation | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of ARFGAP3 protein | CTD | PMID:35688186 | SB 431542 | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARFGAP3 mRNA | CTD | PMID:27188386 | serpentine asbestos | affects expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Asbestos and Serpentine affects the expression of ARFGAP3 mRNA | CTD | PMID:24160326 | silicon dioxide | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ARFGAP3 mRNA | CTD | PMID:25895662 | silicon dioxide | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of ARFGAP3 mRNA | CTD | PMID:23221170 | sodium arsenite | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ARFGAP3 mRNA | CTD | PMID:34032870 | testosterone | decreases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Testosterone deficiency results in decreased expression of ARFGAP3 mRNA | CTD | PMID:33848595 | tetrachloromethane | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of ARFGAP3 mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of ARFGAP3 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARFGAP3 mRNA] | CTD | PMID:31150632 | thapsigargin | increases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of ARFGAP3 mRNA | CTD | PMID:22378314 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of ARFGAP3 protein | CTD | PMID:35544339 | trichostatin A | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ARFGAP3 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | ARFGAP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARFGAP3 mRNA | CTD | PMID:27188386 | tunicamycin | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Tunicamycin results in increased expression of ARFGAP3 mRNA | CTD | PMID:17127020 | tunicamycin | increases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of ARFGAP3 mRNA | CTD | PMID:22378314 | valproic acid | affects expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ARFGAP3 mRNA | CTD | PMID:17292431 and PMID:17963808 | valproic acid | increases expression | ISO | Arfgap3 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ARFGAP3 mRNA | CTD | PMID:19136453 | valproic acid | decreases expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ARFGAP3 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | ARFGAP3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ARFGAP3 mRNA | CTD | PMID:25979313 | |