Tarbp2 (Tarbp2 subunit of RISC loading complex) - Rat Genome Database

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Gene: Tarbp2 (Tarbp2 subunit of RISC loading complex) Rattus norvegicus
Analyze
Symbol: Tarbp2
Name: Tarbp2 subunit of RISC loading complex
RGD ID: 1307375
Description: Predicted to enable several functions, including RNA binding activity; protein N-terminus binding activity; and protein homodimerization activity. Predicted to contribute to pre-miRNA binding activity. Predicted to be involved in several processes, including negative regulation of defense response to virus by host; negative regulation of gene expression; and positive regulation of viral genome replication. Predicted to act upstream of or within several processes, including positive regulation of muscle cell differentiation; regulation of gene expression; and spermatid development. Predicted to be located in nuclear body. Predicted to be part of RISC complex and RISC-loading complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human TARBP2 (TARBP2 subunit of RISC loading complex); PARTICIPATES IN microRNA pathway; INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC363006; MGC124970; RISC-loading complex subunit TARBP2; TAR (HIV) RNA binding protein 2; TAR (HIV-1) RNA binding protein 2; TARBP2, RISC loading complex RNA binding subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27133,649,118 - 133,654,306 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7133,649,090 - 133,654,314 (+)Ensembl
Rnor_6.07144,121,688 - 144,126,860 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,121,744 - 144,126,857 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,912,728 - 141,918,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,272,043 - 141,273,188 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17141,348,156 - 141,349,625 (+)NCBI
Celera7130,076,808 - 130,081,909 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
cytoplasm  (IBA,IEA,ISO,ISS)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA)
perinuclear region of cytoplasm  (IEA)
RISC complex  (IBA,IEA,ISO,ISS)
RISC-loading complex  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The widespread regulation of microRNA biogenesis, function and decay. Krol J, etal., Nat Rev Genet. 2010 Sep;11(9):597-610. Epub 2010 Jul 27.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10369260   PMID:11641396   PMID:12477932   PMID:15973356   PMID:16357216   PMID:16424907   PMID:17452327   PMID:17531811   PMID:18178619   PMID:19820710   PMID:22503104   PMID:23435228  
PMID:23661684   PMID:25416956   PMID:25557550   PMID:25608000   PMID:27159388   PMID:28174252  


Genomics

Comparative Map Data
Tarbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27133,649,118 - 133,654,306 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7133,649,090 - 133,654,314 (+)Ensembl
Rnor_6.07144,121,688 - 144,126,860 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,121,744 - 144,126,857 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,912,728 - 141,918,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,272,043 - 141,273,188 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17141,348,156 - 141,349,625 (+)NCBI
Celera7130,076,808 - 130,081,909 (+)NCBICelera
Cytogenetic Map7q36NCBI
TARBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,500,923 - 53,506,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1253,500,921 - 53,506,431 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,894,707 - 53,900,215 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,180,972 - 52,186,482 (+)NCBINCBI36hg18NCBI36
Build 341252,180,971 - 52,186,480NCBI
Celera1253,545,063 - 53,550,573 (+)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1250,934,287 - 50,939,797 (+)NCBIHuRef
CHM1_11253,861,761 - 53,867,271 (+)NCBICHM1_1
T2T-CHM13v2.01253,466,928 - 53,472,436 (+)NCBI
Tarbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,423,327 - 102,432,111 (+)NCBIGRCm39mm39
GRCm39 Ensembl15102,426,627 - 102,432,111 (+)Ensembl
GRCm3815102,516,077 - 102,523,676 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,518,192 - 102,523,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,348,677 - 102,354,107 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615102,346,493 - 102,351,708 (+)NCBImm8
Celera15104,676,011 - 104,681,441 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.65NCBI
Tarbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458793,759 - 798,806 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458793,753 - 798,755 (+)NCBIChiLan1.0ChiLan1.0
TARBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11236,031,822 - 36,038,080 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,031,818 - 36,038,008 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01235,246,937 - 35,253,378 (-)NCBIMhudiblu_PPA_v0panPan3
TARBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,715,157 - 1,720,050 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,715,158 - 1,726,885 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,530,279 - 44,535,121 (+)NCBI
ROS_Cfam_1.0271,719,078 - 1,723,920 (-)NCBI
ROS_Cfam_1.0 Ensembl271,719,077 - 1,723,754 (-)Ensembl
UMICH_Zoey_3.1271,736,610 - 1,741,453 (-)NCBI
UNSW_CanFamBas_1.0271,719,877 - 1,724,720 (-)NCBI
UU_Cfam_GSD_1.02744,931,979 - 44,936,821 (+)NCBI
Tarbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,384,789 - 62,390,032 (-)NCBI
SpeTri2.0NW_00493651210,774,793 - 10,780,041 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TARBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,718,688 - 18,723,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,718,588 - 18,723,843 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2519,154,223 - 19,159,472 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TARBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,601,634 - 49,607,097 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,602,113 - 49,606,816 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037196,446,953 - 196,453,171 (-)NCBIVero_WHO_p1.0
Tarbp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,597,428 - 1,603,504 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249041,598,422 - 1,603,494 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH134482  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,654,086 - 133,654,303 (+)MAPPERmRatBN7.2
Rnor_6.07144,126,641 - 144,126,857NCBIRnor6.0
Rnor_5.07141,918,636 - 141,918,852UniSTSRnor5.0
Celera7130,081,690 - 130,081,906UniSTS
RH 3.4 Map71051.41UniSTS
Cytogenetic Map7q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:53
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000064661
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 41 33 17 33 3 69 28 39 11
Low 8 16 8 2 8 8 8 5 7 2 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001034941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC104690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000064661   ⟹   ENSRNOP00000061329
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,649,090 - 133,654,296 (+)Ensembl
Rnor_6.0 Ensembl7144,121,744 - 144,126,857 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103193   ⟹   ENSRNOP00000095105
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,649,090 - 133,654,314 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107019   ⟹   ENSRNOP00000076381
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,649,090 - 133,654,296 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118634   ⟹   ENSRNOP00000079010
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,649,198 - 133,654,306 (+)Ensembl
RefSeq Acc Id: NM_001034941   ⟹   NP_001030113
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,190 - 133,654,306 (+)NCBI
Rnor_6.07144,121,744 - 144,126,860 (+)NCBI
Rnor_5.07141,912,728 - 141,918,855 (+)NCBI
RGSC_v3.47141,272,043 - 141,273,188 (+)RGD
Celera7130,076,808 - 130,081,909 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242429   ⟹   XP_006242491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,133 - 133,654,306 (+)NCBI
Rnor_6.07144,121,692 - 144,126,860 (+)NCBI
Rnor_5.07141,912,728 - 141,918,855 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006242430   ⟹   XP_006242492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,197 - 133,654,306 (+)NCBI
Rnor_6.07144,121,688 - 144,126,860 (+)NCBI
Rnor_5.07141,912,728 - 141,918,855 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079652   ⟹   XP_038935580
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,126 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079653   ⟹   XP_038935581
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,123 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079654   ⟹   XP_038935582
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,118 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079655   ⟹   XP_038935583
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,120 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079657   ⟹   XP_038935585
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,120 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079658   ⟹   XP_038935586
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,165 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079659   ⟹   XP_038935587
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,164 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079660   ⟹   XP_038935588
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,537 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079661   ⟹   XP_038935589
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,196 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079662   ⟹   XP_038935590
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,159 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079663   ⟹   XP_038935591
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,165 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079664   ⟹   XP_038935592
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,147 - 133,654,306 (+)NCBI
RefSeq Acc Id: XM_039079665   ⟹   XP_038935593
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27133,649,195 - 133,654,306 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001030113   ⟸   NM_001034941
- UniProtKB: Q3SWU0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006242491   ⟸   XM_006242429
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006242492   ⟸   XM_006242430
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000061329   ⟸   ENSRNOT00000064661
RefSeq Acc Id: XP_038935582   ⟸   XM_039079654
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038935583   ⟸   XM_039079655
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038935585   ⟸   XM_039079657
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038935581   ⟸   XM_039079653
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038935580   ⟸   XM_039079652
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038935592   ⟸   XM_039079664
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038935590   ⟸   XM_039079662
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038935587   ⟸   XM_039079659
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038935586   ⟸   XM_039079658
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038935591   ⟸   XM_039079663
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038935593   ⟸   XM_039079665
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038935589   ⟸   XM_039079661
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038935588   ⟸   XM_039079660
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000076381   ⟸   ENSRNOT00000107019
RefSeq Acc Id: ENSRNOP00000079010   ⟸   ENSRNOT00000118634
RefSeq Acc Id: ENSRNOP00000095105   ⟸   ENSRNOT00000103193
Protein Domains
DRBM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3SWU0-F1-model_v2 AlphaFold Q3SWU0 1-365 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695703
Promoter ID:EPDNEW_R6228
Type:initiation region
Name:Tarbp2_1
Description:TARBP2, RISC loading complex RNA binding subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07144,121,714 - 144,121,774EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307375 AgrOrtholog
BioCyc Gene G2FUF-31932 BioCyc
Ensembl Genes ENSRNOG00000042355 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000061329 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000076381.1 UniProtKB/TrEMBL
  ENSRNOP00000079010 ENTREZGENE
  ENSRNOP00000079010.1 UniProtKB/TrEMBL
  ENSRNOP00000095105.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064661 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000103193.1 UniProtKB/TrEMBL
  ENSRNOT00000107019.1 UniProtKB/TrEMBL
  ENSRNOT00000118634 ENTREZGENE
  ENSRNOT00000118634.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7107060 IMAGE-MGC_LOAD
InterPro dsRBD_dom UniProtKB/Swiss-Prot
  TRBP2 UniProtKB/Swiss-Prot
  TRBP2_DSRM_1 UniProtKB/Swiss-Prot
  TRBP2_DSRM_2 UniProtKB/Swiss-Prot
  TRBP2_DSRM_3 UniProtKB/Swiss-Prot
KEGG Report rno:363006 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124970 IMAGE-MGC_LOAD
NCBI Gene 363006 ENTREZGENE
PANTHER PTHR46205:SF1 UniProtKB/Swiss-Prot
Pfam dsrm UniProtKB/Swiss-Prot
PhenoGen Tarbp2 PhenoGen
PROSITE DS_RBD UniProtKB/Swiss-Prot
SMART DSRM UniProtKB/Swiss-Prot
UniProt A0A8I5Y6G0_RAT UniProtKB/TrEMBL
  A0A8I5ZPX6_RAT UniProtKB/TrEMBL
  A0A8I6AKV0_RAT UniProtKB/TrEMBL
  Q3SWU0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-05 Tarbp2  Tarbp2 subunit of RISC loading complex  Tarbp2  TARBP2 subunit of RISC loading complex  Name changed 629549 APPROVED
2019-04-02 Tarbp2  TARBP2 subunit of RISC loading complex  Tarbp2  TARBP2, RISC loading complex RNA binding subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-23 Tarbp2  TARBP2, RISC loading complex RNA binding subunit  Tarbp2  TAR (HIV-1) RNA binding protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Tarbp2  TAR (HIV-1) RNA binding protein 2  Tarbp2  TAR (HIV) RNA binding protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tarbp2  TAR (HIV) RNA binding protein 2  Tarbp2_predicted  TAR (HIV) RNA binding protein 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tarbp2_predicted  TAR (HIV) RNA binding protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED