(+)-dexrazoxane multiple interactions ISO RGD:1552438 6480464 [Dexrazoxane co-treated with Idarubicin] results in increased expression of XRCC6 mRNA CTD PMID:28973540 (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA] CTD PMID:26332274 1,2-dimethylhydrazine increases expression ISO RGD:1552438 6480464 1, 2-Dimethylhydrazine results in increased expression of XRCC6 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:1552438 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of XRCC6 mRNA CTD PMID:22206623 17beta-estradiol multiple interactions ISO RGD:732846 6480464 3 more ... CTD PMID:11179685 17beta-estradiol increases expression ISO RGD:732846 6480464 Estradiol results in increased expression of XRCC6 mRNA CTD PMID:11179685 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:732846 6480464 Metribolone promotes the reaction [NDRG1 protein binds to XRCC6 protein] CTD PMID:17220478 2,2'-dithiodiethanol multiple interactions ISO RGD:732846 6480464 [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732846 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of XRCC6 mRNA], Tetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to XRCC6 gene] CTD PMID:11179685 , PMID:28681081 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of XRCC6 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1552438 6480464 Tetrachlorodibenzodioxin affects the expression of XRCC6 mRNA CTD PMID:21570461 3,3'-diindolylmethane multiple interactions ISO RGD:732846 6480464 3, 3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of XRCC6 mRNA] CTD PMID:11179685 5-aza-2'-deoxycytidine affects methylation ISO RGD:732846 6480464 Decitabine affects the methylation of XRCC6 gene CTD PMID:17630775 5-fluorouracil multiple interactions ISO RGD:732846 6480464 XRCC6 mRNA results in increased susceptibility to [Fluorouracil co-treated with Cisplatin], XRCC6 protein results in increased susceptibility to [Fluorouracil co-treated with Cisplatin] CTD PMID:18546291 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:23969067 7,12-dimethyltetraphene multiple interactions ISO RGD:1552438 6480464 A gene mutant form inhibits the reaction [9 more ... CTD PMID:25448685 7,12-dimethyltetraphene increases expression ISO RGD:1552438 6480464 9 more ... CTD PMID:25448685 acrolein multiple interactions ISO RGD:732846 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of XRCC6 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of XRCC6 mRNA CTD PMID:32699268 acrylonitrile increases expression EXP 6480464 Acrylonitrile results in increased expression of XRCC6 mRNA CTD PMID:26332274 acrylonitrile multiple interactions EXP 6480464 Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA] more ... CTD PMID:26332274 aldehydo-D-glucose multiple interactions ISO RGD:732846 6480464 [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 aldehydo-D-glucose multiple interactions ISO RGD:1552438 6480464 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one inhibits the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of XRCC6 protein] more ... CTD PMID:31672611 alpha-pinene multiple interactions ISO RGD:732846 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of XRCC6 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of XRCC6 mRNA CTD PMID:32699268 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of XRCC6 mRNA CTD PMID:16483693 Aroclor 1254 decreases expression ISO RGD:1552438 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of XRCC6 mRNA CTD PMID:23650126 arsenite(3-) multiple interactions ISO RGD:732846 6480464 arsenite inhibits the reaction [G3BP1 protein binds to XRCC6 protein] CTD PMID:32406909 arsenous acid decreases expression ISO RGD:732846 6480464 Arsenic Trioxide results in decreased expression of XRCC6 mRNA CTD PMID:15761015 benzene affects expression ISO RGD:732846 6480464 Benzene affects the expression of XRCC6 mRNA CTD PMID:16188086 benzo[a]pyrene increases expression ISO RGD:1552438 6480464 Benzo(a)pyrene results in increased expression of XRCC6 mRNA CTD PMID:22228805 Benzo[ghi]perylene increases expression ISO RGD:732846 6480464 1, 12-benzoperylene results in increased expression of XRCC6 mRNA CTD PMID:31518672 Benzo[ghi]perylene decreases expression ISO RGD:732846 6480464 1, 12-benzoperylene results in decreased expression of XRCC6 mRNA CTD PMID:31518672 biphenyl-4-amine multiple interactions ISO RGD:732846 6480464 Propolis inhibits the reaction [4-biphenylamine results in decreased expression of XRCC6 protein], TP53 protein inhibits the reaction [4-biphenylamine results in decreased expression of XRCC6 mRNA] CTD PMID:32905825 , PMID:33847444 biphenyl-4-amine decreases expression ISO RGD:732846 6480464 4-biphenylamine results in decreased expression of XRCC6 mRNA, 4-biphenylamine results in decreased expression of XRCC6 protein CTD PMID:32905825 , PMID:33847444 bisphenol A multiple interactions ISO RGD:1552438 6480464 [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA] more ... CTD PMID:25693136 , PMID:27082013 bisphenol A affects expression ISO RGD:732846 6480464 bisphenol A affects the expression of XRCC6 mRNA CTD PMID:30903817 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of XRCC6 mRNA CTD PMID:30816183 , PMID:32528016 bisphenol A affects methylation ISO RGD:1552438 6480464 bisphenol A affects the methylation of XRCC6 promoter CTD PMID:27334623 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of XRCC6 mRNA CTD PMID:25181051 , PMID:27208089 bupivacaine multiple interactions ISO RGD:1552438 6480464 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one inhibits the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of XRCC6 protein] more ... CTD PMID:31672611 bupivacaine increases expression ISO RGD:1552438 6480464 Bupivacaine results in increased expression of XRCC6 protein CTD PMID:31672611 calcitriol decreases expression ISO RGD:732846 6480464 Calcitriol results in decreased expression of XRCC6 mRNA CTD PMID:15951637 , PMID:16847355 carbon nanotube increases expression ISO RGD:1552438 6480464 Nanotubes, Carbon results in increased expression of XRCC6 mRNA CTD PMID:25554681 cisplatin multiple interactions ISO RGD:732846 6480464 XRCC6 mRNA results in increased susceptibility to [Fluorouracil co-treated with Cisplatin], XRCC6 protein results in increased susceptibility to [Fluorouracil co-treated with Cisplatin] CTD PMID:18546291 cisplatin decreases expression ISO RGD:1552438 6480464 Cisplatin results in decreased expression of XRCC6 mRNA CTD PMID:21151649 copper(II) sulfate decreases expression ISO RGD:732846 6480464 Copper Sulfate results in decreased expression of XRCC6 mRNA CTD PMID:19549813 coumestrol increases expression ISO RGD:732846 6480464 Coumestrol results in increased expression of XRCC6 mRNA CTD PMID:19167446 crocidolite asbestos affects expression ISO RGD:732846 6480464 Asbestos, Crocidolite affects the expression of XRCC6 mRNA CTD PMID:17331233 curcumin decreases expression ISO RGD:732846 6480464 Curcumin results in decreased expression of XRCC6 mRNA CTD PMID:17596214 cyclophosphamide decreases expression ISO RGD:1552438 6480464 Cyclophosphamide results in decreased expression of XRCC6 mRNA CTD PMID:21041162 D-glucose multiple interactions ISO RGD:732846 6480464 [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 D-glucose multiple interactions ISO RGD:1552438 6480464 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one inhibits the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of XRCC6 protein] more ... CTD PMID:31672611 dexamethasone decreases expression ISO RGD:1552438 6480464 Dexamethasone results in decreased expression of XRCC6 mRNA CTD PMID:21041162 diarsenic trioxide decreases expression ISO RGD:732846 6480464 Arsenic Trioxide results in decreased expression of XRCC6 mRNA CTD PMID:15761015 dicrotophos decreases expression ISO RGD:732846 6480464 dicrotophos results in decreased expression of XRCC6 mRNA CTD PMID:28302478 diethylstilbestrol decreases expression ISO RGD:1552438 6480464 Diethylstilbestrol results in decreased expression of XRCC6 mRNA CTD PMID:21041162 doxorubicin multiple interactions ISO RGD:1552438 6480464 [STAT3 gene mutant form results in increased susceptibility to Doxorubicin] which results in increased expression of XRCC6 protein more ... CTD PMID:24812279 doxorubicin increases expression ISO RGD:732846 6480464 Doxorubicin results in increased expression of XRCC6 mRNA CTD PMID:29803840 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of XRCC6 mRNA CTD PMID:27181935 doxorubicin multiple interactions EXP 6480464 Fungal Polysaccharides inhibits the reaction [Doxorubicin results in decreased expression of XRCC6 mRNA] CTD PMID:27181935 doxorubicin increases expression ISO RGD:1552438 6480464 Doxorubicin results in increased expression of XRCC6 protein CTD PMID:24812279 enzyme inhibitor multiple interactions ISO RGD:732846 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of XRCC6 protein CTD PMID:23301498 ethanol multiple interactions ISO RGD:732846 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of XRCC6 mRNA CTD PMID:29432896 fenthion increases expression ISO RGD:732846 6480464 Fenthion results in increased expression of XRCC6 mRNA CTD PMID:33221015 fenthion multiple interactions ISO RGD:732846 6480464 [terbufos co-treated with Fenthion] results in decreased expression of XRCC6 mRNA, [terbufos co-treated with Fenthion] results in decreased expression of XRCC6 protein CTD PMID:33221015 folic acid multiple interactions ISO RGD:1552438 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of XRCC6 mRNA CTD PMID:22206623 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of XRCC6 mRNA CTD PMID:33387578 glucose multiple interactions ISO RGD:732846 6480464 [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 glucose multiple interactions ISO RGD:1552438 6480464 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one inhibits the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of XRCC6 protein] more ... CTD PMID:31672611 idarubicin multiple interactions ISO RGD:1552438 6480464 [Dexrazoxane co-treated with Idarubicin] results in increased expression of XRCC6 mRNA CTD PMID:28973540 ivermectin decreases expression ISO RGD:732846 6480464 Ivermectin results in decreased expression of XRCC6 protein CTD PMID:32959892 lead(0) decreases expression ISO RGD:732846 6480464 Lead results in decreased expression of XRCC6 mRNA CTD PMID:19921347 lead(2+) decreases expression ISO RGD:732846 6480464 Lead results in decreased expression of XRCC6 mRNA CTD PMID:19921347 lipopolysaccharide decreases expression ISO RGD:1552438 6480464 Lipopolysaccharides results in decreased expression of XRCC6 mRNA CTD PMID:12057914 methyl methanesulfonate decreases expression ISO RGD:732846 6480464 Methyl Methanesulfonate results in decreased expression of XRCC6 mRNA CTD PMID:23649840 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA] CTD PMID:26332274 N-nitrosodiethylamine multiple interactions ISO RGD:1552438 6480464 MG 262 inhibits the reaction [XRCC6 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TRP53 protein]] more ... CTD PMID:18506893 N-nitrosodiethylamine decreases response to substance ISO RGD:1552438 6480464 XRCC6 protein results in decreased susceptibility to Diethylnitrosamine CTD PMID:18506893 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of XRCC6 mRNA CTD PMID:25729387 ozone multiple interactions ISO RGD:732846 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of XRCC6 mRNA more ... CTD PMID:32699268 paracetamol affects expression ISO RGD:1552438 6480464 Acetaminophen affects the expression of XRCC6 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of XRCC6 mRNA CTD PMID:33387578 phosphoramide mustard affects expression EXP 6480464 phosphoramide mustard affects the expression of XRCC6 mRNA, phosphoramide mustard affects the expression of XRCC6 protein CTD PMID:25497287 phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of XRCC6 mRNA CTD PMID:26708502 potassium bromate multiple interactions ISO RGD:1552438 6480464 [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA] more ... CTD PMID:25693136 , PMID:27082013 potassium bromate increases response to substance ISO RGD:1552438 6480464 XRCC6 gene mutant form results in increased susceptibility to potassium bromate CTD PMID:25693136 , PMID:27082013 resveratrol decreases expression EXP 6480464 Resveratrol results in decreased expression of XRCC6 mRNA CTD PMID:33775663 resveratrol multiple interactions ISO RGD:732846 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of XRCC6 mRNA CTD PMID:23557933 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of XRCC6 mRNA CTD PMID:27900601 sodium arsenite increases expression ISO RGD:732846 6480464 sodium arsenite results in increased expression of XRCC6 mRNA CTD PMID:12016162 sodium arsenite decreases expression ISO RGD:1552438 6480464 sodium arsenite results in decreased expression of XRCC6 mRNA CTD PMID:16014739 sulindac sulfide increases expression ISO RGD:732846 6480464 sulindac sulfide results in increased expression of XRCC6 mRNA CTD PMID:12734198 tamoxifen decreases expression EXP 6480464 Tamoxifen results in decreased expression of XRCC6 protein CTD PMID:17219426 terbufos decreases expression ISO RGD:732846 6480464 terbufos results in decreased expression of XRCC6 protein CTD PMID:33221015 terbufos increases expression ISO RGD:732846 6480464 terbufos results in increased expression of XRCC6 mRNA CTD PMID:33221015 terbufos multiple interactions ISO RGD:732846 6480464 [terbufos co-treated with Fenthion] results in decreased expression of XRCC6 mRNA, [terbufos co-treated with Fenthion] results in decreased expression of XRCC6 protein CTD PMID:33221015 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of XRCC6 mRNA CTD PMID:31150632 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of XRCC6 mRNA CTD PMID:34492290 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of XRCC6 mRNA CTD PMID:25729387 trichostatin A increases acetylation ISO RGD:732846 6480464 trichostatin A results in increased acetylation of XRCC6 protein CTD PMID:27064363 trimellitic anhydride increases expression ISO RGD:1552438 6480464 trimellitic anhydride results in increased expression of XRCC6 mRNA CTD PMID:19042947 vitamin E increases expression ISO RGD:732846 6480464 Vitamin E results in increased expression of XRCC6 mRNA CTD PMID:19244175 vorinostat decreases expression ISO RGD:732846 6480464 vorinostat results in decreased expression of XRCC6 protein CTD PMID:16928817 wortmannin multiple interactions ISO RGD:732846 6480464 [wortmannin co-treated with docetaxel] results in decreased expression of XRCC6 protein CTD PMID:20878124
