XRCC6 (X-ray repair cross complementing 6) - Rat Genome Database

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Gene: XRCC6 (X-ray repair cross complementing 6) Homo sapiens
Analyze
Symbol: XRCC6
Name: X-ray repair cross complementing 6
RGD ID: 732846
HGNC Page HGNC
Description: Exhibits several functions, including 5'-deoxyribose-5-phosphate lyase activity; ATPase activity; and cyclin binding activity. Contributes to DNA end binding activity and double-stranded telomeric DNA binding activity. Involved in several processes, including cellular response to gamma radiation; double-strand break repair via classical nonhomologous end joining; and regulation of transcription, DNA-templated. Localizes to several cellular components, including nonhomologous end joining complex; nucleus; and protein-DNA complex. Biomarker of basal cell carcinoma and squamous cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; ATP-dependent DNA helicase II, 70 kDa subunit; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; G22P1; Ku autoantigen p70 subunit; Ku autoantigen, 70kDa; KU70; lupus Ku autoantigen protein p70; ML8; thyroid autoantigen 70kD (Ku antigen); thyroid autoantigen 70kDa (Ku antigen); thyroid-lupus autoantigen p70; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6; X-ray repair cross-complementing protein 6
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: XRCC6P1   XRCC6P3   XRCC6P4   XRCC6P5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,621,119 - 41,664,048 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2241,621,163 - 41,664,048 (+)EnsemblGRCh38hg38GRCh38
GRCh382241,621,295 - 41,664,041 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,017,299 - 42,060,045 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,347,241 - 40,389,998 (+)NCBINCBI36hg18NCBI36
Build 342240,341,794 - 40,384,552NCBI
Celera2225,823,724 - 25,866,486 (+)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,982,897 - 25,025,516 (+)NCBIHuRef
CHM1_12241,977,215 - 42,020,083 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(+)-dexrazoxane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
2,2'-dithiodiethanol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3'-diindolylmethane  (EXP)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acrolein  (EXP)
acrylonitrile  (ISO)
aldehydo-D-glucose  (EXP,ISO)
alpha-pinene  (EXP)
ammonium chloride  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
Benzo[ghi]perylene  (EXP)
biphenyl-4-amine  (EXP)
bisphenol A  (EXP,ISO)
bupivacaine  (ISO)
calcitriol  (EXP)
carbon nanotube  (ISO)
cisplatin  (EXP,ISO)
copper(II) sulfate  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP)
curcumin  (EXP)
cyclophosphamide  (ISO)
D-glucose  (EXP,ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP)
dicrotophos  (EXP)
diethylstilbestrol  (ISO)
doxorubicin  (EXP,ISO)
enzyme inhibitor  (EXP)
ethanol  (EXP)
folic acid  (ISO)
glucose  (EXP,ISO)
idarubicin  (ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
lipopolysaccharide  (ISO)
methyl methanesulfonate  (EXP)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (ISO)
phosphoramide mustard  (ISO)
potassium bromate  (ISO)
rotenone  (ISO)
sodium arsenite  (EXP,ISO)
sulindac sulfide  (EXP)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
topotecan  (ISO)
trichostatin A  (EXP)
trimellitic anhydride  (ISO)
vitamin E  (EXP,ISO)
vorinostat  (EXP)
wortmannin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1537839   PMID:1608402   PMID:1639139   PMID:2466842   PMID:2917966   PMID:7699019   PMID:7882982   PMID:7957065   PMID:8240370   PMID:8422676   PMID:8524317   PMID:8621488  
PMID:8702520   PMID:8760815   PMID:8954777   PMID:9200330   PMID:9223317   PMID:9312071   PMID:9362500   PMID:9368068   PMID:9430697   PMID:9488450   PMID:9742108   PMID:9798959  
PMID:9826654   PMID:9914162   PMID:10026262   PMID:10064605   PMID:10207052   PMID:10213687   PMID:10219089   PMID:10377944   PMID:10400681   PMID:10409678   PMID:10446239   PMID:10508516  
PMID:10514012   PMID:10570175   PMID:10591208   PMID:10750018   PMID:10757784   PMID:10783163   PMID:10823961   PMID:10880505   PMID:10984620   PMID:11070027   PMID:11112778   PMID:11158303  
PMID:11162511   PMID:11196700   PMID:11238996   PMID:11239001   PMID:11279128   PMID:11314007   PMID:11328876   PMID:11406603   PMID:11457852   PMID:11493912   PMID:11749722   PMID:11751391  
PMID:11790298   PMID:11796732   PMID:11821378   PMID:12023295   PMID:12065431   PMID:12091904   PMID:12145306   PMID:12145307   PMID:12145308   PMID:12145309   PMID:12171929   PMID:12177300  
PMID:12324457   PMID:12368356   PMID:12377759   PMID:12467650   PMID:12477932   PMID:12494870   PMID:12509254   PMID:12518983   PMID:12519782   PMID:12547193   PMID:12551933   PMID:12664628  
PMID:12664629   PMID:12672812   PMID:12750264   PMID:12756247   PMID:12867423   PMID:12897160   PMID:14570916   PMID:14627815   PMID:14702039   PMID:14734561   PMID:14744259   PMID:14991539  
PMID:15019772   PMID:15023334   PMID:15075319   PMID:15100233   PMID:15123719   PMID:15140983   PMID:15159402   PMID:15205477   PMID:15220460   PMID:15231748   PMID:15272235   PMID:15302935  
PMID:15367688   PMID:15383276   PMID:15383534   PMID:15385968   PMID:15461802   PMID:15489334   PMID:15520013   PMID:15613478   PMID:15635413   PMID:15640154   PMID:15723802   PMID:15782130  
PMID:15824061   PMID:15827325   PMID:15905197   PMID:15910003   PMID:15958648   PMID:16009940   PMID:16051665   PMID:16055720   PMID:16097034   PMID:16159877   PMID:16166097   PMID:16169070  
PMID:16226712   PMID:16291214   PMID:16344560   PMID:16360032   PMID:16407974   PMID:16440001   PMID:16448389   PMID:16490787   PMID:16541024   PMID:16611982   PMID:16713581   PMID:16794079  
PMID:16857680   PMID:16889989   PMID:17124166   PMID:17159921   PMID:17187679   PMID:17202845   PMID:17213819   PMID:17220478   PMID:17242407   PMID:17283121   PMID:17304248   PMID:17308091  
PMID:17314511   PMID:17334224   PMID:17361185   PMID:17389609   PMID:17389650   PMID:17479409   PMID:17496833   PMID:17617666   PMID:17620599   PMID:17671430   PMID:17714764   PMID:17725712  
PMID:17768380   PMID:17885668   PMID:17952468   PMID:17971348   PMID:17982634   PMID:18000863   PMID:18164703   PMID:18208821   PMID:18303113   PMID:18362350   PMID:18374504   PMID:18385154  
PMID:18406329   PMID:18487076   PMID:18546291   PMID:18706726   PMID:18710944   PMID:18710952   PMID:18757043   PMID:18768166   PMID:18809223   PMID:18850631   PMID:18990028   PMID:19041431  
PMID:19064572   PMID:19074885   PMID:19116388   PMID:19118032   PMID:19134120   PMID:19135240   PMID:19135898   PMID:19177010   PMID:19181665   PMID:19219618   PMID:19237606   PMID:19247369  
PMID:19251090   PMID:19265193   PMID:19303849   PMID:19394292   PMID:19408343   PMID:19467273   PMID:19661379   PMID:19666485   PMID:19672258   PMID:19692349   PMID:19738201   PMID:19750561  
PMID:19794960   PMID:19805454   PMID:19809793   PMID:19833092   PMID:19906305   PMID:19913121   PMID:19946888   PMID:20020773   PMID:20047046   PMID:20080577   PMID:20127252   PMID:20157594  
PMID:20224553   PMID:20360068   PMID:20368362   PMID:20383123   PMID:20394854   PMID:20453000   PMID:20467437   PMID:20493174   PMID:20496165   PMID:20496270   PMID:20504901   PMID:20522537  
PMID:20538911   PMID:20570964   PMID:20610542   PMID:20628086   PMID:20697560   PMID:20711232   PMID:20718578   PMID:21042724   PMID:21042904   PMID:21044950   PMID:21070772   PMID:21075794  
PMID:21081666   PMID:21107697   PMID:21108727   PMID:21113133   PMID:21116096   PMID:21145461   PMID:21146485   PMID:21172662   PMID:21187428   PMID:21209461   PMID:21256093   PMID:21280222  
PMID:21304054   PMID:21349273   PMID:21398614   PMID:21423092   PMID:21454661   PMID:21512205   PMID:21521024   PMID:21549307   PMID:21556760   PMID:21575261   PMID:21575865   PMID:21671178  
PMID:21679440   PMID:21756904   PMID:21825151   PMID:21847364   PMID:21873635   PMID:21888893   PMID:21900206   PMID:21907836   PMID:21969602   PMID:21972126   PMID:21988832   PMID:22037767  
PMID:22079093   PMID:22179609   PMID:22226402   PMID:22322857   PMID:22399625   PMID:22412018   PMID:22442688   PMID:22446626   PMID:22451927   PMID:22455395   PMID:22504172   PMID:22504299  
PMID:22524845   PMID:22535209   PMID:22544055   PMID:22586326   PMID:22593040   PMID:22617044   PMID:22623428   PMID:22658674   PMID:22681889   PMID:22745744   PMID:22751105   PMID:22863883  
PMID:22939629   PMID:22990118   PMID:22993329   PMID:23098447   PMID:23145133   PMID:23154512   PMID:23182705   PMID:23184937   PMID:23247197   PMID:23271361   PMID:23322783   PMID:23329831  
PMID:23349316   PMID:23393345   PMID:23414517   PMID:23443559   PMID:23457464   PMID:23463506   PMID:23620595   PMID:23624778   PMID:23650516   PMID:23677788   PMID:23685356   PMID:23745766  
PMID:23863879   PMID:23926104   PMID:24095731   PMID:24140708   PMID:24147044   PMID:24187467   PMID:24244333   PMID:24305947   PMID:24324074   PMID:24332808   PMID:24382701   PMID:24457600  
PMID:24610814   PMID:24615008   PMID:24695737   PMID:24711643   PMID:24769731   PMID:24942867   PMID:24965446   PMID:24981860   PMID:25000480   PMID:25046228   PMID:25281560   PMID:25299772  
PMID:25437307   PMID:25496916   PMID:25569644   PMID:25574025   PMID:25665578   PMID:25695595   PMID:25702660   PMID:25735744   PMID:25749521   PMID:25756210   PMID:25756610   PMID:25796446  
PMID:25798074   PMID:25817432   PMID:25818292   PMID:25852083   PMID:25852190   PMID:25855964   PMID:25921289   PMID:25940091   PMID:25941166   PMID:25963833   PMID:26055322   PMID:26149939  
PMID:26170170   PMID:26175416   PMID:26186194   PMID:26209609   PMID:26318153   PMID:26337656   PMID:26344197   PMID:26359349   PMID:26360636   PMID:26446488   PMID:26496610   PMID:26527279  
PMID:26549023   PMID:26641092   PMID:26712563   PMID:26754263   PMID:26772202   PMID:26774286   PMID:26797321   PMID:26816005   PMID:26831064   PMID:26876283   PMID:26913518   PMID:26964895  
PMID:26974709   PMID:26976509   PMID:26979993   PMID:27025967   PMID:27067600   PMID:27129234   PMID:27248496   PMID:27328741   PMID:27342126   PMID:27384990   PMID:27402161   PMID:27455247  
PMID:27497341   PMID:27545878   PMID:27593939   PMID:27607350   PMID:27609421   PMID:27626385   PMID:27637333   PMID:27684187   PMID:27705800   PMID:27716483   PMID:27741411   PMID:27769014  
PMID:27783955   PMID:27825805   PMID:27829214   PMID:27895153   PMID:27998981   PMID:28035050   PMID:28153717   PMID:28192407   PMID:28238784   PMID:28302793   PMID:28330616   PMID:28345663  
PMID:28415827   PMID:28443643   PMID:28514442   PMID:28515276   PMID:28533407   PMID:28581483   PMID:28655758   PMID:28712289   PMID:28712728   PMID:28717247   PMID:28720717   PMID:28821586  
PMID:28927264   PMID:28959974   PMID:28977666   PMID:29101126   PMID:29104487   PMID:29117863   PMID:29128334   PMID:29229926   PMID:29298432   PMID:29331416   PMID:29367615   PMID:29397516  
PMID:29467282   PMID:29490077   PMID:29507755   PMID:29568061   PMID:29656893   PMID:29676528   PMID:29743367   PMID:29791485   PMID:29844126   PMID:29845934   PMID:29912634   PMID:29961565  
PMID:29985131   PMID:30021884   PMID:30032073   PMID:30085293   PMID:30196744   PMID:30209976   PMID:30249103   PMID:30258100   PMID:30273928   PMID:30320910   PMID:30415952   PMID:30425250  
PMID:30442662   PMID:30455355   PMID:30463901   PMID:30559450   PMID:30575818   PMID:30585729   PMID:30792309   PMID:30804502   PMID:30833792   PMID:30940169   PMID:30940648   PMID:30942445  
PMID:30948266   PMID:31059266   PMID:31091453   PMID:31160578   PMID:31180492   PMID:31239290   PMID:31243170   PMID:31300519   PMID:31405213   PMID:31446546   PMID:31501420   PMID:31536960  
PMID:31586073   PMID:31620119   PMID:31667665   PMID:31685992   PMID:31690330   PMID:31740976   PMID:31765243   PMID:31827253   PMID:32006067   PMID:32041737   PMID:32051553   PMID:32076604  
PMID:32129710   PMID:32296183   PMID:32416067   PMID:32427332   PMID:32529326   PMID:32572027   PMID:32780723   PMID:32814053   PMID:32877691   PMID:32937373   PMID:33005030   PMID:33132134  


Genomics

Comparative Map Data
XRCC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,621,119 - 41,664,048 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2241,621,163 - 41,664,048 (+)EnsemblGRCh38hg38GRCh38
GRCh382241,621,295 - 41,664,041 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,017,299 - 42,060,045 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,347,241 - 40,389,998 (+)NCBINCBI36hg18NCBI36
Build 342240,341,794 - 40,384,552NCBI
Celera2225,823,724 - 25,866,486 (+)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,982,897 - 25,025,516 (+)NCBIHuRef
CHM1_12241,977,215 - 42,020,083 (+)NCBICHM1_1
Xrcc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,868,805 - 81,924,286 (+)NCBIGRCm39mm39
GRCm39 Ensembl1581,872,036 - 81,924,286 (+)Ensembl
GRCm381581,987,833 - 82,040,085 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,987,835 - 82,040,085 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,846,799 - 81,870,514 (+)NCBIGRCm37mm9NCBIm37
MGSCv361581,843,555 - 81,867,327 (+)NCBImm8
Celera1584,138,425 - 84,161,793 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.33NCBI
Xrcc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27113,542,992 - 113,563,762 (+)NCBI
Rnor_6.0 Ensembl7123,259,761 - 123,280,612 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07123,259,881 - 123,280,613 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07123,244,581 - 123,265,278 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,401,944 - 120,422,923 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,436,196 - 120,457,039 (+)NCBI
Celera7109,858,919 - 109,879,605 (+)NCBICelera
Cytogenetic Map7q34NCBI
Xrcc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541327,135,805 - 27,159,750 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541327,135,785 - 27,158,344 (+)NCBIChiLan1.0ChiLan1.0
XRCC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12240,626,191 - 40,643,540 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,603,038 - 40,643,314 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02222,516,281 - 22,557,379 (+)NCBIMhudiblu_PPA_v0panPan3
XRCC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,637,905 - 23,661,618 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,638,237 - 23,661,480 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,571,669 - 23,594,987 (-)NCBI
ROS_Cfam_1.01024,383,246 - 24,406,874 (-)NCBI
UMICH_Zoey_3.11024,100,152 - 24,123,487 (-)NCBI
UNSW_CanFamBas_1.01024,421,552 - 24,445,083 (-)NCBI
UU_Cfam_GSD_1.01024,595,424 - 24,619,012 (-)NCBI
Xrcc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,293,429 - 7,315,475 (-)NCBI
SpeTri2.0NW_004936492303,843 - 325,812 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XRCC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl56,903,496 - 6,929,083 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.156,903,496 - 6,929,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,274,586 - 4,300,429 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XRCC6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,160,459 - 24,204,237 (+)NCBI
ChlSab1.1 Ensembl1924,160,483 - 24,206,320 (+)Ensembl
Xrcc6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247526,987,456 - 7,010,834 (-)NCBI

Position Markers
SGC34657  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371094,968,887 - 94,969,269UniSTSGRCh37
GRCh37X149,400,871 - 149,401,005UniSTSGRCh37
Build 36X149,151,529 - 149,151,663RGDNCBI36
CeleraX149,648,944 - 149,649,078RGD
Celera1088,710,101 - 88,710,483UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map10q23.33UniSTS
Cytogenetic Map22q13.2UniSTS
HuRef1088,596,833 - 88,597,215UniSTS
HuRefX138,264,246 - 138,264,380UniSTS
GeneMap99-GB4 RH MapX347.01UniSTS
Whitehead-RH MapX314.8UniSTS
NCBI RH MapX733.4UniSTS
RH27888  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,042,965 - 42,043,066UniSTSGRCh37
Build 362240,372,911 - 40,373,012RGDNCBI36
Celera2225,849,402 - 25,849,503RGD
Cytogenetic Map22q13.2UniSTS
HuRef2225,008,034 - 25,008,135UniSTS
RH11334  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,033,392 - 42,033,506UniSTSGRCh37
Build 362240,363,338 - 40,363,452RGDNCBI36
Celera2225,839,824 - 25,839,938RGD
Cytogenetic Map22q13.2UniSTS
HuRef2224,998,862 - 24,998,976UniSTS
G67490  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,042,820 - 42,043,186UniSTSGRCh37
Build 362240,372,766 - 40,373,132RGDNCBI36
Celera2225,849,257 - 25,849,623RGD
Cytogenetic Map22q13.2UniSTS
HuRef2225,007,889 - 25,008,255UniSTS
csnpg22p1-pcr12-2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,059,531 - 42,060,105UniSTSGRCh37
Build 362240,389,477 - 40,390,051RGDNCBI36
Celera2225,865,965 - 25,866,539RGD
Cytogenetic Map22q13.2UniSTS
HuRef2225,024,995 - 25,025,569UniSTS
D22S1267  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,053,444 - 42,053,599UniSTSGRCh37
Build 362240,383,390 - 40,383,545RGDNCBI36
Celera2225,859,884 - 25,860,033RGD
Cytogenetic Map22q13.2UniSTS
HuRef2225,018,917 - 25,019,063UniSTS
D22S1245  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,059,769 - 42,059,939UniSTSGRCh37
GRCh37X149,399,171 - 149,399,341UniSTSGRCh37
Build 36X149,149,829 - 149,149,999RGDNCBI36
CeleraX149,647,244 - 149,647,414RGD
Celera2225,866,203 - 25,866,373UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map22q13.2UniSTS
HuRefX138,262,546 - 138,262,716UniSTS
HuRef2225,025,233 - 25,025,403UniSTS
Stanford-G3 RH Map221335.0UniSTS
NCBI RH Map22204.9UniSTS
GeneMap99-G3 RH Map221335.0UniSTS
WI-18866  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,059,806 - 42,059,939UniSTSGRCh37
Build 362240,389,752 - 40,389,885RGDNCBI36
Celera2225,866,240 - 25,866,373RGD
Cytogenetic Map22q13.2UniSTS
HuRef2225,025,270 - 25,025,403UniSTS
GeneMap99-GB4 RH Map22126.85UniSTS
Whitehead-RH Map22155.3UniSTS
G22P1_2710  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,059,577 - 42,060,043UniSTSGRCh37
Build 362240,389,523 - 40,389,989RGDNCBI36
Celera2225,866,011 - 25,866,477RGD
HuRef2225,025,041 - 25,025,507UniSTS
GDB:190933  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q13.2UniSTS
D22S731  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q13.2UniSTS
Whitehead-YAC Contig Map22 UniSTS
D10S2161  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q13.2UniSTS
Stanford-G3 RH Map221339.0UniSTS
Whitehead-YAC Contig Map10 UniSTS
NCBI RH Map22205.8UniSTS
GeneMap99-G3 RH Map221339.0UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR766hsa-miR-766-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Target Of
Summary Value
Count of predictions:1857
Count of miRNA genes:421
Interacting mature miRNAs:458
Transcripts:ENST00000359308, ENST00000360079, ENST00000402580, ENST00000405506, ENST00000405878, ENST00000428575, ENST00000464116, ENST00000478914
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 4 1 1 9 1 10 2 1 1 36 14
Medium 2428 2973 1721 620 1934 462 4345 2185 3707 416 1413 1594 171 1204 2788 4
Low 7 18 4 3 7 2 2 9 25 2 10 4 4 1 2 2
Below cutoff 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001288976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK055786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY870329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI222708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ217843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU584415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU751953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU902323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD683757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR456492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR542219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS330042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS545602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA647513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA718140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB057280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC383335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC386009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH794620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M32865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S38729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z83840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000359308   ⟹   ENSP00000352257
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,621,350 - 41,664,039 (+)Ensembl
RefSeq Acc Id: ENST00000360079   ⟹   ENSP00000353192
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,621,119 - 41,664,039 (+)Ensembl
RefSeq Acc Id: ENST00000402580   ⟹   ENSP00000384941
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,621,295 - 41,664,048 (+)Ensembl
RefSeq Acc Id: ENST00000405506   ⟹   ENSP00000384082
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,621,983 - 41,664,034 (+)Ensembl
RefSeq Acc Id: ENST00000405878   ⟹   ENSP00000384257
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,621,461 - 41,664,039 (+)Ensembl
RefSeq Acc Id: ENST00000428575   ⟹   ENSP00000403679
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,621,163 - 41,664,048 (+)Ensembl
RefSeq Acc Id: ENST00000464116
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,621,285 - 41,628,318 (+)Ensembl
RefSeq Acc Id: ENST00000478914
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,656,953 - 41,661,699 (+)Ensembl
RefSeq Acc Id: NM_001288976   ⟹   NP_001275905
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,621,295 - 41,664,041 (+)NCBI
HuRef2224,982,769 - 25,025,516 (+)NCBI
CHM1_12241,977,394 - 42,020,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001288977   ⟹   NP_001275906
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,621,295 - 41,664,041 (+)NCBI
HuRef2224,982,769 - 25,025,516 (+)NCBI
CHM1_12241,977,215 - 42,020,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001288978   ⟹   NP_001275907
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,621,295 - 41,664,041 (+)NCBI
HuRef2224,982,769 - 25,025,516 (+)NCBI
CHM1_12241,977,215 - 42,020,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001469   ⟹   NP_001460
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,621,295 - 41,664,041 (+)NCBI
GRCh372242,017,250 - 42,060,052 (+)NCBI
Build 362240,347,241 - 40,389,998 (+)NCBI Archive
HuRef2224,982,769 - 25,025,516 (+)NCBI
CHM1_12241,977,215 - 42,020,083 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001460   ⟸   NM_001469
- Peptide Label: isoform 1
- UniProtKB: P12956 (UniProtKB/Swiss-Prot),   A0A024R1N4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001275906   ⟸   NM_001288977
- Peptide Label: isoform 2
- UniProtKB: P12956 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275907   ⟸   NM_001288978
- Peptide Label: isoform 3
- UniProtKB: B1AHC9 (UniProtKB/TrEMBL),   B4DE32 (UniProtKB/TrEMBL),   B4E356 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001275905   ⟸   NM_001288976
- Peptide Label: isoform 1
- UniProtKB: P12956 (UniProtKB/Swiss-Prot),   A0A024R1N4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000352257   ⟸   ENST00000359308
RefSeq Acc Id: ENSP00000353192   ⟸   ENST00000360079
RefSeq Acc Id: ENSP00000403679   ⟸   ENST00000428575
RefSeq Acc Id: ENSP00000384941   ⟸   ENST00000402580
RefSeq Acc Id: ENSP00000384082   ⟸   ENST00000405506
RefSeq Acc Id: ENSP00000384257   ⟸   ENST00000405878
Protein Domains
Ku   SAP

Promoters
RGD ID:6800306
Promoter ID:HG_KWN:42999
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000402409,   ENST00000405878,   OTTHUMT00000104124,   OTTHUMT00000321686,   OTTHUMT00000321718,   UC003BAP.1,   UC003BAR.1,   UC003BAS.1
Position:
Human AssemblyChrPosition (strand)Source
Build 362240,345,716 - 40,347,807 (-)MPROMDB
RGD ID:6851460
Promoter ID:EP73531
Type:initiation region
Name:HS_G22P1
Description:Thyroid autoantigen 70kDa (Ku antigen).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 362240,347,245 - 40,347,305EPD
RGD ID:13604272
Promoter ID:EPDNEW_H28320
Type:initiation region
Name:XRCC6_1
Description:X-ray repair cross complementing 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,621,306 - 41,621,366EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 22q12.3-13.33(chr22:37061769-50738932)x3 copy number gain See cases [RCV000051684] Chr22:37061769..50738932 [GRCh38]
Chr22:37457809..51177360 [GRCh37]
Chr22:35787755..49524226 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:33768441-50739977)x3 copy number gain See cases [RCV000051682] Chr22:33768441..50739977 [GRCh38]
Chr22:34164428..51178405 [GRCh37]
Chr22:32494428..49525271 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 copy number gain See cases [RCV000133646] Chr22:16916608..50739836 [GRCh38]
Chr22:17397498..51178264 [GRCh37]
Chr22:15777498..49525130 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 copy number gain See cases [RCV000134730] Chr22:16916743..50739785 [GRCh38]
Chr22:17397633..51178213 [GRCh37]
Chr22:15777633..49525079 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q13.1-13.33(chr22:40202014-50735806)x3 copy number gain See cases [RCV000134513] Chr22:40202014..50735806 [GRCh38]
Chr22:40598018..51174234 [GRCh37]
Chr22:38927964..49521100 [NCBI36]
Chr22:22q13.1-13.33
pathogenic
GRCh38/hg38 22q13.2(chr22:41645339-42565798)x1 copy number loss See cases [RCV000136528] Chr22:41645339..42565798 [GRCh38]
Chr22:42041343..42961804 [GRCh37]
Chr22:40371289..41291748 [NCBI36]
Chr22:22q13.2
uncertain significance
GRCh38/hg38 22q13.2(chr22:41277822-42414957)x3 copy number gain See cases [RCV000136785] Chr22:41277822..42414957 [GRCh38]
Chr22:41673826..42810963 [GRCh37]
Chr22:40003772..41140907 [NCBI36]
Chr22:22q13.2
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237518)x3 copy number gain See cases [RCV000240091] Chr22:16054691..51237518 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q12.3-13.33(chr22:35728929-51220961)x3 copy number gain See cases [RCV000240469] Chr22:35728929..51220961 [GRCh37]
Chr22:22q12.3-13.33
pathogenic
GRCh37/hg19 22q13.1-13.33(chr22:40425714-51220961)x3 copy number gain See cases [RCV000240459] Chr22:40425714..51220961 [GRCh37]
Chr22:22q13.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51220902)x3 copy number gain See cases [RCV000446956] Chr22:16054691..51220902 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:42033410-42101539)x3 copy number gain See cases [RCV000448749] Chr22:42033410..42101539 [GRCh37]
Chr22:22q13.2
likely benign
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237463)x3 copy number gain See cases [RCV000448847] Chr22:16054691..51237463 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:41835094-42756616)x3 copy number gain See cases [RCV000511241] Chr22:41835094..42756616 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838) copy number gain See cases [RCV000510873] Chr22:16888900..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838)x3 copy number gain See cases [RCV000512333] Chr22:16888900..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
NC_000022.11:g.(?_41301335)_(42070317_?)del deletion Common variable immunodeficiency 4 [RCV000648330] Chr22:41301335..42070317 [GRCh38]
Chr22:41697339..42466321 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q13.2(chr22:41849322-42756616)x3 copy number gain not provided [RCV000684486] Chr22:41849322..42756616 [GRCh37]
Chr22:22q13.2
likely pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054667-51243435)x3 copy number gain not provided [RCV000741689] Chr22:16054667..51243435 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51195728)x3 copy number gain not provided [RCV000741691] Chr22:16114244..51195728 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51211392)x3 copy number gain not provided [RCV000741692] Chr22:16114244..51211392 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q12.2-13.33(chr22:30654764-51197838)x3 copy number gain not provided [RCV001007181] Chr22:30654764..51197838 [GRCh37]
Chr22:22q12.2-13.33
pathogenic
NM_001469.5(XRCC6):c.960+10G>A single nucleotide variant not provided [RCV000959799] Chr22:41647092 [GRCh38]
Chr22:42043096 [GRCh37]
Chr22:22q13.2
benign
GRCh37/hg19 22q13.1-13.33(chr22:40502364-51197838)x3 copy number gain not provided [RCV001007502] Chr22:40502364..51197838 [GRCh37]
Chr22:22q13.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:41871935-42026428)x1 copy number loss not provided [RCV001007503] Chr22:41871935..42026428 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16888899-51197838)x3 copy number gain not provided [RCV000846344] Chr22:16888899..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:41853620-42385978)x1 copy number loss not provided [RCV001258783] Chr22:41853620..42385978 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16197005-51224252)x3 copy number gain See cases [RCV001263056] Chr22:16197005..51224252 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
NC_000022.10:g.(?_41697339)_(42466321_?)del deletion Common variable immunodeficiency 4 [RCV001305750] Chr22:41697339..42466321 [GRCh37]
Chr22:22q13.2
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4055 AgrOrtholog
COSMIC XRCC6 COSMIC
Ensembl Genes ENSG00000196419 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000352257 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000353192 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000384082 UniProtKB/TrEMBL
  ENSP00000384257 UniProtKB/Swiss-Prot
  ENSP00000384941 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000403679 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENST00000359308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000360079 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000402580 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000405506 UniProtKB/TrEMBL
  ENST00000405878 UniProtKB/Swiss-Prot
  ENST00000428575 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.290.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.410 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.970.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000196419 GTEx
HGNC ID HGNC:4055 ENTREZGENE
Human Proteome Map XRCC6 Human Proteome Map
InterPro Ku70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ku70/Ku80_beta-barrel_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ku70_bridge/pillars_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ku_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ku_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPOC-like_C_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:2547 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 2547 ENTREZGENE
OMIM 152690 OMIM
Pfam Ku_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ku_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF02735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA28467 PharmGKB
PIRSF Ku70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Ku78 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF100939 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF68906 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs ku70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R1N4 ENTREZGENE, UniProtKB/TrEMBL
  B1AHC9 ENTREZGENE, UniProtKB/TrEMBL
  B4DE32 ENTREZGENE, UniProtKB/TrEMBL
  B4E356 ENTREZGENE, UniProtKB/TrEMBL
  P12956 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B1AHC8 UniProtKB/Swiss-Prot
  F5H1I8 UniProtKB/TrEMBL
  Q6FG89 UniProtKB/Swiss-Prot
  Q9UCQ2 UniProtKB/Swiss-Prot
  Q9UCQ3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-07 XRCC6  X-ray repair cross complementing 6  XRCC6  X-ray repair complementing defective repair in Chinese hamster cells 6  Symbol and/or name change 5135510 APPROVED