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Gene: Tmprss6 (transmembrane serine protease 6) Rattus norvegicus
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Symbol: Tmprss6
Name: transmembrane serine protease 6
Description: Predicted to have serine-type endopeptidase activity. Predicted to be involved in several processes, including fibrinolysis; proteolysis; and regulation of transcription by RNA polymerase II. Predicted to localize to the extracellular space; integral component of membrane; and plasma membrane. Human ortholog(s) of this gene implicated in microcytic anemia. Orthologous to human TMPRSS6 (transmembrane serine protease 6); INTERACTS WITH 2,4-dinitrotoluene; 7,12-dimethyltetraphene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC315388; transmembrane protease serine 6; transmembrane protease, serine 6
Orthologs:
Homo sapiens (human) : TMPRSS6 (transmembrane serine protease 6)  HGNC  Alliance
Mus musculus (house mouse) : Tmprss6 (transmembrane serine protease 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmprss6 (transmembrane serine protease 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TMPRSS6 (transmembrane serine protease 6)
Canis lupus familiaris (dog) : TMPRSS6 (transmembrane serine protease 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmprss6 (transmembrane serine protease 6)
Sus scrofa (pig) : TMPRSS6 (transmembrane serine protease 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07119,659,323 - 119,689,953 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07119,649,831 - 119,680,259 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,391,730 - 116,419,671 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17116,425,992 - 116,456,922 (-)NCBI
Celera7106,329,190 - 106,359,893 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tmprss6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307138
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.