Amigo2 (adhesion molecule with Ig like domain 2) - Rat Genome Database

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Gene: Amigo2 (adhesion molecule with Ig like domain 2) Rattus norvegicus
Analyze
Symbol: Amigo2
Name: adhesion molecule with Ig like domain 2
RGD ID: 727911
Description: Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and negative regulation of neuron apoptotic process. Predicted to be located in membrane and nucleus. Orthologous to human AMIGO2 (adhesion molecule with Ig like domain 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ali1; Alivin 1; alivin-1; AMIGO-2; amphoterin induced gene 2; amphoterin-induced protein 2; transmembrane protein AMIGO2; transmembrane protein AMIGO2-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87130,270,639 - 130,273,735 (-)NCBIGRCr8
mRatBN7.27128,391,493 - 128,394,589 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7128,390,412 - 128,394,695 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7130,188,505 - 130,191,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07132,414,037 - 132,417,141 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07132,329,495 - 132,332,533 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07138,704,124 - 138,707,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7138,704,126 - 138,707,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,327,613 - 138,330,710 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47135,966,794 - 135,969,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17136,043,230 - 136,046,184 (-)NCBI
Celera7124,880,421 - 124,883,447 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chlorpyrifos  (ISO)
cisplatin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dieldrin  (EXP)
diethyl maleate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
indometacin  (ISO)
irinotecan  (ISO)
ketamine  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-Nitrosopyrrolidine  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
piroxicam  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
nucleus  (IEA)
plasma membrane  (NAS)

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Amigo2-upregulation in Tumour Cells Facilitates Their Attachment to Liver Endothelial Cells Resulting in Liver Metastases. Kanda Y, etal., Sci Rep. 2017 Mar 8;7:43567. doi: 10.1038/srep43567.
3. AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. Kuja-Panula J, etal., J Cell Biol 2003 Mar 17;160(6):963-73.
4. AMIGO2 modulates T cell functions and its deficiency in mice ameliorates experimental autoimmune encephalomyelitis. Li Z, etal., Brain Behav Immun. 2017 May;62:110-123. doi: 10.1016/j.bbi.2017.01.009. Epub 2017 Feb 1.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
7. Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons. Ono T, etal., J Neurosci 2003 Jul 2;23(13):5887-96.
8. AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation. Park H, etal., J Cell Biol. 2015 Nov 9;211(3):619-37. doi: 10.1083/jcb.201503113.
9. DEGA/AMIGO-2, a leucine-rich repeat family member, differentially expressed in human gastric adenocarcinoma: effects on ploidy, chromosomal stability, cell adhesion/migration and tumorigenicity. Rabenau KE, etal., Oncogene. 2004 Jun 24;23(29):5056-67. doi: 10.1038/sj.onc.1207681.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:24613359  


Genomics

Comparative Map Data
Amigo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87130,270,639 - 130,273,735 (-)NCBIGRCr8
mRatBN7.27128,391,493 - 128,394,589 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7128,390,412 - 128,394,695 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7130,188,505 - 130,191,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07132,414,037 - 132,417,141 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07132,329,495 - 132,332,533 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07138,704,124 - 138,707,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7138,704,126 - 138,707,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,327,613 - 138,330,710 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47135,966,794 - 135,969,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17136,043,230 - 136,046,184 (-)NCBI
Celera7124,880,421 - 124,883,447 (-)NCBICelera
Cytogenetic Map7q36NCBI
AMIGO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,075,707 - 47,079,959 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1247,075,707 - 47,079,959 (-)EnsemblGRCh38hg38GRCh38
GRCh371247,469,490 - 47,473,742 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361245,755,757 - 45,759,915 (-)NCBINCBI36Build 36hg18NCBI36
Build 341245,755,756 - 45,759,915NCBI
Celera1246,266,530 - 46,270,780 (-)NCBICelera
Cytogenetic Map12q13.11NCBI
HuRef1244,500,413 - 44,504,656 (-)NCBIHuRef
CHM1_11247,434,869 - 47,439,118 (-)NCBICHM1_1
T2T-CHM13v2.01247,036,477 - 47,040,734 (-)NCBIT2T-CHM13v2.0
Amigo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,141,955 - 97,145,168 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1597,142,006 - 97,145,168 (-)EnsemblGRCm39 Ensembl
GRCm381597,244,074 - 97,247,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,244,125 - 97,247,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,074,505 - 97,077,718 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361597,072,159 - 97,075,156 (-)NCBIMGSCv36mm8
Celera1599,379,756 - 99,382,756 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1552.91NCBI
Amigo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555006,134,736 - 6,138,075 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555006,134,736 - 6,138,075 (-)NCBIChiLan1.0ChiLan1.0
AMIGO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21047,087,432 - 47,090,754 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11247,084,383 - 47,087,467 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01241,652,954 - 41,656,393 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11242,525,099 - 42,528,399 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1242,525,858 - 42,527,426 (+)Ensemblpanpan1.1panPan2
AMIGO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,507,426 - 7,510,015 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,507,489 - 7,509,054 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2738,798,999 - 38,802,268 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,573,450 - 7,576,716 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,573,601 - 7,576,762 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1277,509,723 - 7,513,046 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,552,000 - 7,555,266 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02739,041,956 - 39,045,226 (-)NCBIUU_Cfam_GSD_1.0
Amigo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494568,004,585 - 68,007,754 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365125,157,175 - 5,159,818 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365125,157,076 - 5,160,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMIGO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl577,642,195 - 77,645,753 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1577,642,144 - 77,645,748 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2580,650,537 - 80,653,629 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AMIGO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11143,281,634 - 43,285,016 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1143,282,518 - 43,284,083 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037203,104,609 - 203,108,095 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Amigo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248165,184,536 - 5,187,659 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248165,184,423 - 5,189,691 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Amigo2
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:27
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000009199
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 28 18 24 11
Low 3 43 57 41 19 41 8 11 46 17 16 8
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000009199   ⟹   ENSRNOP00000009199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7138,704,126 - 138,707,221 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097759   ⟹   ENSRNOP00000085327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7128,390,412 - 128,394,695 (-)Ensembl
RefSeq Acc Id: NM_182816   ⟹   NP_877968
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87130,270,639 - 130,273,735 (-)NCBI
mRatBN7.27128,391,493 - 128,394,589 (-)NCBI
Rnor_6.07138,704,125 - 138,707,221 (-)NCBI
Rnor_5.07138,327,613 - 138,330,710 (-)NCBI
RGSC_v3.47135,966,794 - 135,969,747 (-)RGD
Celera7124,880,421 - 124,883,447 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063263369   ⟹   XP_063119439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87130,270,639 - 130,273,614 (-)NCBI
RefSeq Acc Id: XM_063263370   ⟹   XP_063119440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87130,270,639 - 130,273,575 (-)NCBI
RefSeq Acc Id: NP_877968   ⟸   NM_182816
- Peptide Label: precursor
- UniProtKB: Q80ZD6 (UniProtKB/Swiss-Prot),   Q7TNJ4 (UniProtKB/Swiss-Prot),   A0A0G2JSI9 (UniProtKB/TrEMBL),   A6KC34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009199   ⟸   ENSRNOT00000009199
RefSeq Acc Id: ENSRNOP00000085327   ⟸   ENSRNOT00000097759
RefSeq Acc Id: XP_063119439   ⟸   XM_063263369
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063119440   ⟸   XM_063263370
- Peptide Label: isoform X1
Protein Domains
Ig-like   Ig-like C2-type   LRRCT   LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TNJ4-F1-model_v2 AlphaFold Q7TNJ4 1-520 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695613
Promoter ID:EPDNEW_R6136
Type:single initiation site
Name:Amigo2_1
Description:adhesion molecule with Ig like domain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07138,707,239 - 138,707,299EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727911 AgrOrtholog
BioCyc Gene G2FUF-32201 BioCyc
Ensembl Genes ENSRNOG00000007032 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009199 UniProtKB/TrEMBL
  ENSRNOT00000097759 ENTREZGENE
  ENSRNOT00000097759.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:300186 UniProtKB/Swiss-Prot
NCBI Gene 300186 ENTREZGENE
PANTHER IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Amigo2 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007032 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSI9 ENTREZGENE, UniProtKB/TrEMBL
  A6KC34 ENTREZGENE, UniProtKB/TrEMBL
  AMGO2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q80ZD6 ENTREZGENE
UniProt Secondary Q80ZD6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Amigo2  adhesion molecule with Ig like domain 2  LOC100364402  transmembrane protein AMIGO2-like  Data merged from RGD:2321058 1643240 APPROVED
2010-05-05 LOC100364402  transmembrane protein AMIGO2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Amigo2  adhesion molecule with Ig like domain 2    amphoterin induced gene 2  Name updated 1299863 APPROVED
2005-07-08 Amigo2  amphoterin induced gene 2    transmembrane protein AMIGO2  Name updated 1299863 APPROVED