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Gene: Cacnb3 (calcium voltage-gated channel auxiliary subunit beta 3) Rattus norvegicus
Symbol: Cacnb3
Name: calcium voltage-gated channel auxiliary subunit beta 3
Description: Exhibits calcium channel regulator activity; protein kinase binding activity; and voltage-gated calcium channel activity. Contributes to high voltage-gated calcium channel activity. Involved in several processes, including calcium ion transport; regulation of ion transmembrane transport; and regulation of nervous system process. Localizes to L-type voltage-gated calcium channel complex and apical plasma membrane. Orthologous to human CACNB3 (calcium voltage-gated channel auxiliary subunit beta 3); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH ammonium chloride; androgen antagonist; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CAB3; CACH3B; calcium channel subunit beta 3; calcium channel voltage-dependent subunit beta 3; calcium channel, voltage-dependent, beta 3 subunit; voltage-dependent L-type calcium channel subunit beta-3
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07140,311,120 - 140,324,902 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,315,368 - 140,324,902 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X114,814,959 - 114,828,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,384,752 - 137,394,283 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17137,461,187 - 137,470,720 (+)NCBI
Celera7126,277,809 - 126,287,303 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cacnb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2248
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.