Gene: Il2rb (interleukin 2 receptor subunit beta) Rattus norvegicus
Symbol: Il2rb
Name: interleukin 2 receptor subunit beta
Description: ENCODES a protein that exhibits interleukin-2 binding; interleukin-2 receptor activity; INVOLVED IN cytokine-mediated signaling pathway; natural killer cell activation; negative regulation of apoptotic process (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Arthritis, Rheumatoid (ortholog); Asthma (ortholog); Autoimmune Diseases (ortholog); FOUND IN cell surface; external side of plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; beta-naphthoflavone; bisphenol A
Type: protein-coding
Also known as: high affinity IL-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; IL2RBC; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; interleukin-2 receptor subunit beta; P70-75
Homo sapiens (human) : IL2RB (interleukin 2 receptor subunit beta)  HGNC  AGR
Mus musculus (house mouse) : Il2rb (interleukin 2 receptor, beta chain)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Il2rb (interleukin 2 receptor subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : IL2RB (interleukin 2 receptor subunit beta)
Canis lupus familiaris (dog) : IL2RB (interleukin 2 receptor subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il2rb (interleukin 2 receptor subunit beta)
more info ...
Is Marker For: QTLs:   MAMTS6_H   MAMTS5_H   MAMTS4_H  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07119,701,338 - 119,716,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07119,690,375 - 119,705,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera7106,371,243 - 106,385,925 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Il2rb
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2896
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE