Racgap1 (Rac GTPase-activating protein 1) - Rat Genome Database

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Gene: Racgap1 (Rac GTPase-activating protein 1) Rattus norvegicus
Analyze
Symbol: Racgap1
Name: Rac GTPase-activating protein 1
RGD ID: 1305912
Description: Predicted to enable several functions, including GTPase activator activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and tubulin binding activity. Predicted to be involved in several processes, including cytoskeleton-dependent cytokinesis; mitotic spindle midzone assembly; and regulation of cell cycle process. Predicted to be located in several cellular components, including cytoplasmic side of plasma membrane; mitotic spindle; and nucleoplasm. Predicted to be part of centralspindlin complex. Predicted to be active in several cellular components, including cleavage furrow; midbody; and spindle midzone. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type IIIb. Orthologous to human RACGAP1 (Rac GTPase activating protein 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC103690014; LOC315298; rac GTPase-activating protein 1-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,629,789 - 132,659,738 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7132,620,595 - 132,659,738 (-)EnsemblGRCr8
mRatBN7.27130,750,936 - 130,780,891 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,750,936 - 130,780,831 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7132,555,040 - 132,584,440 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,780,620 - 134,810,026 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,693,146 - 134,722,541 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,277,303 - 141,308,849 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,277,312 - 141,307,233 (-)Ensemblrn6Rnor6.0
Rnor_5.07138,713,215 - 138,728,271 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47138,366,356 - 138,395,716 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7127,232,693 - 127,262,334 (-)NCBICelera
RGSC_v3.17138,443,204 - 138,463,026 (-)NCBI
Cytogenetic Map7q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
AM-251  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-D-glucosamine  (EXP)
beta-lapachone  (ISO)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gallic acid  (ISO)
genistein  (ISO)
geraniol  (ISO)
hexadecanoic acid  (ISO)
indometacin  (ISO)
isoflavones  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
lithium atom  (EXP)
lithium hydride  (EXP)
lucanthone  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methimazole  (EXP)
methylphenidate  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nickel dichloride  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
PhIP  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
acrosomal vesicle  (IEA)
centralspindlin complex  (IBA,IEA,ISO)
cleavage furrow  (IBA,IEA,ISO)
cytoplasm  (IEA)
cytoplasmic side of plasma membrane  (IEA,ISO)
cytoplasmic vesicle  (IEA)
cytoskeleton  (IEA)
Flemming body  (IEA)
membrane  (IEA)
midbody  (IBA,IEA,ISO)
mitochondrion  (ISO)
mitotic spindle  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
plasma membrane  (IEA)
spindle  (IEA,ISO)
spindle midzone  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10493933   PMID:10979956   PMID:11085985   PMID:11278976   PMID:11287179   PMID:11782313   PMID:12477932   PMID:12590651   PMID:15642749   PMID:16103226   PMID:16129829   PMID:16236794  
PMID:18511905   PMID:19199708   PMID:19468302   PMID:23235882   PMID:34800366  


Genomics

Comparative Map Data
Racgap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,629,789 - 132,659,738 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7132,620,595 - 132,659,738 (-)EnsemblGRCr8
mRatBN7.27130,750,936 - 130,780,891 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,750,936 - 130,780,831 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7132,555,040 - 132,584,440 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,780,620 - 134,810,026 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,693,146 - 134,722,541 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,277,303 - 141,308,849 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,277,312 - 141,307,233 (-)Ensemblrn6Rnor6.0
Rnor_5.07138,713,215 - 138,728,271 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47138,366,356 - 138,395,716 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7127,232,693 - 127,262,334 (-)NCBICelera
RGSC_v3.17138,443,204 - 138,463,026 (-)NCBI
Cytogenetic Map7q36NCBI
RACGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,989,162 - 50,033,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,976,923 - 50,033,136 (-)Ensemblhg38GRCh38
GRCh371250,382,945 - 50,419,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,669,212 - 48,705,488 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341248,669,211 - 48,705,488NCBI
Celera1249,179,065 - 49,215,304 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,414,446 - 47,451,548 (-)NCBIHuRef
CHM1_11250,349,102 - 50,385,463 (-)NCBICHM1_1
T2T-CHM13v2.01249,952,172 - 49,996,504 (-)NCBIT2T-CHM13v2.0
Racgap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,518,377 - 99,549,504 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,518,377 - 99,549,537 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381599,620,496 - 99,651,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,620,496 - 99,651,656 (-)Ensemblmm10GRCm38
MGSCv371599,450,927 - 99,482,052 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361599,448,530 - 99,479,655 (-)NCBIMGSCv36mm8
Celera15101,775,878 - 101,807,252 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Racgap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547581,134 - 616,087 (-)Ensembl
ChiLan1.0NW_004955547584,885 - 615,883 (-)NCBIChiLan1.0ChiLan1.0
RACGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,163,317 - 44,199,581 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,160,108 - 44,196,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,729,885 - 38,766,063 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,625,763 - 39,660,040 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,625,796 - 39,672,256 (+)EnsemblpanPan2panpan1.1
RACGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,689,914 - 4,718,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,689,483 - 4,727,933 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2741,541,242 - 41,569,279 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0274,737,980 - 4,766,051 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,738,129 - 4,775,802 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,702,991 - 4,731,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,692,808 - 4,720,859 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,935,897 - 41,964,171 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Racgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,468,262 - 65,499,692 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,665,208 - 7,689,112 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,665,144 - 7,696,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RACGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,904,712 - 15,943,609 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1515,894,314 - 15,943,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,400,485 - 16,403,961 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RACGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,218,987 - 46,260,477 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1146,220,090 - 46,254,602 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037199,866,951 - 199,902,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Racgap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,273,856 - 2,303,375 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248162,268,879 - 2,303,305 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Racgap1
330 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:97
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000024796, ENSRNOT00000071885
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)7132099939137014596Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
RH128358  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q36UniSTS
RH131552  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,751,103 - 130,751,303 (+)MAPPERmRatBN7.2
Rnor_6.07141,277,471 - 141,277,670NCBIRnor6.0
Rnor_6.07139,571,006 - 139,571,205NCBIRnor6.0
Rnor_5.07138,712,841 - 138,713,040UniSTSRnor5.0
Rnor_5.0X115,782,174 - 115,782,373UniSTSRnor5.0
RGSC_v3.47138,365,982 - 138,366,181UniSTSRGSC3.4
Celera7127,232,319 - 127,232,518UniSTS
RH 3.4 Map71076.3UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 91 59 6 355 191 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000071885   ⟹   ENSRNOP00000067834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7132,629,807 - 132,659,738 (-)Ensembl
mRatBN7.2 Ensembl7130,750,936 - 130,780,831 (-)Ensembl
Rnor_6.0 Ensembl7141,277,312 - 141,307,233 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097336   ⟹   ENSRNOP00000081316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7132,620,595 - 132,659,738 (-)Ensembl
mRatBN7.2 Ensembl7130,750,936 - 130,773,854 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000121619   ⟹   ENSRNOP00000105034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7132,630,331 - 132,659,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123541   ⟹   ENSRNOP00000110421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7132,630,331 - 132,659,738 (-)Ensembl
RefSeq Acc Id: NM_001108112   ⟹   NP_001101582
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87132,630,331 - 132,659,738 (-)NCBI
mRatBN7.27130,751,478 - 130,780,891 (-)NCBI
Rnor_6.07141,277,845 - 141,307,298 (-)NCBI
Rnor_5.07138,713,215 - 138,728,271 (-)NCBI
RGSC_v3.47138,366,356 - 138,395,716 (-)RGD
Celera7127,232,693 - 127,262,334 (-)RGD
Sequence:
RefSeq Acc Id: XM_006257400   ⟹   XP_006257462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87132,629,789 - 132,659,689 (-)NCBI
mRatBN7.27130,750,936 - 130,780,855 (-)NCBI
Rnor_6.07141,277,303 - 141,307,250 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079329   ⟹   XP_038935257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87132,629,789 - 132,645,628 (-)NCBI
mRatBN7.27130,750,936 - 130,766,740 (-)NCBI
RefSeq Acc Id: NP_001101582   ⟸   NM_001108112
- UniProtKB: B2GV02 (UniProtKB/TrEMBL),   M0RDX1 (UniProtKB/TrEMBL),   A0A9K3Y6X7 (UniProtKB/TrEMBL),   A0A8I5ZS98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257462   ⟸   XM_006257400
- Peptide Label: isoform X1
- UniProtKB: B2GV02 (UniProtKB/TrEMBL),   M0RDX1 (UniProtKB/TrEMBL),   A0A9K3Y6X7 (UniProtKB/TrEMBL),   A0A8I5ZS98 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067834   ⟸   ENSRNOT00000071885
RefSeq Acc Id: XP_038935257   ⟸   XM_039079329
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000081316   ⟸   ENSRNOT00000097336
Ensembl Acc Id: ENSRNOP00000110421   ⟸   ENSRNOT00000123541
Ensembl Acc Id: ENSRNOP00000105034   ⟸   ENSRNOT00000121619
Protein Domains
Phorbol-ester/DAG-type   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GV02-F1-model_v2 AlphaFold B2GV02 1-626 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695647
Promoter ID:EPDNEW_R6172
Type:multiple initiation site
Name:Racgap1_1
Description:Rac GTPase-activating protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07141,307,227 - 141,307,287EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305912 AgrOrtholog
BioCyc Gene G2FUF-32064 BioCyc
Ensembl Genes ENSRNOG00000049033 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071885 ENTREZGENE
  ENSRNOT00000071885.3 UniProtKB/TrEMBL
  ENSRNOT00000097336.1 UniProtKB/TrEMBL
  ENSRNOT00000123541 ENTREZGENE
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9090730 IMAGE-MGC_LOAD
InterPro C1-like_sf UniProtKB/TrEMBL
  Prot_Kinase_C-like_PE/DAG-bd UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
KEGG Report rno:315298 UniProtKB/TrEMBL
MGC_CLONE MGC:187874 IMAGE-MGC_LOAD
NCBI Gene 315298 ENTREZGENE
PANTHER RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
  RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PhenoGen Racgap1 PhenoGen
PROSITE RHOGAP UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049033 RatGTEx
SMART RhoGAP UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP Rho_GAP UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A8I5ZS98 ENTREZGENE, UniProtKB/TrEMBL
  A0A9K3Y6X7 ENTREZGENE, UniProtKB/TrEMBL
  B2GV02 ENTREZGENE, UniProtKB/TrEMBL
  M0RDX1 ENTREZGENE
UniProt Secondary M0RDX1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Racgap1  Rac GTPase-activating protein 1  LOC103690014  rac GTPase-activating protein 1-like  Data merged from RGD:9270228 737654 PROVISIONAL
2014-08-25 LOC103690014  rac GTPase-activating protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Racgap1  Rac GTPase-activating protein 1   Racgap1_predicted  Rac GTPase-activating protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Racgap1_predicted  Rac GTPase-activating protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED