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Gene: Tspo (translocator protein) Rattus norvegicus
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Symbol: Tspo
Name: translocator protein
Description: Exhibits androgen binding activity and benzodiazepine receptor activity. Involved in several processes, including neurogenesis; positive regulation of cell death; and regulation of reactive oxygen species metabolic process. Localizes to the mitochondrial outer membrane. Orthologous to human TSPO (translocator protein); PARTICIPATES IN heme biosynthetic pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: benzodiazepin receptor; Benzodiazepin receptor (peripheral); benzodiazepine receptor, peripheral; Bzrp; MBR; mitochondrial benzodiazepine receptor; PBR; peripheral-type benzodiazepine receptor; PKBS; Ptbzr; PTBZR02; RATPTBZR02
Orthologs:
Homo sapiens (human) : TSPO (translocator protein)  HGNC  Alliance
Mus musculus (house mouse) : Tspo (translocator protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tspo (translocator protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TSPO (translocator protein)
Canis lupus familiaris (dog) : TSPO (translocator protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tspo (translocator protein)
Sus scrofa (pig) : TSPO (translocator protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07124,460,358 - 124,470,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07124,449,361 - 124,459,090 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,597,084 - 121,599,342 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17121,631,313 - 121,633,572 (+)NCBI
Celera7111,031,561 - 111,041,788 (+)NCBICelera
Cytogenetic Map7q34NCBI
RH 3.4 Map7906.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tspo
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2228
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.