Chkb (choline kinase beta) - Rat Genome Database

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Gene: Chkb (choline kinase beta) Rattus norvegicus
Analyze
Symbol: Chkb
Name: choline kinase beta
RGD ID: 61826
Description: Enables choline kinase activity. Predicted to be involved in CDP-choline pathway and phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within muscle organ development. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (choline kinase beta); PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Chetk; Chkl; choline kinase-like; choline/ethanolamine kinase; choline/ethanolamine kinase beta; CK; CKB; CKEKB; EK; ethanolamine kinase
RGD Orthologs
Human
Mouse
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27120,500,960 - 120,504,359 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7120,500,984 - 120,504,461 (-)Ensembl
Rnor_6.07130,404,818 - 130,408,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,404,832 - 130,408,187 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07130,089,639 - 130,093,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,746,749 - 127,750,104 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17127,780,978 - 127,784,334 (-)NCBI
Celera7116,973,588 - 116,976,943 (-)NCBICelera
RH 3.4 Map7949.5RGD
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Complementary DNA sequence for a 42 kDa rat kidney choline/ethanolamine kinase. Aoyama C, etal., Biochim Biophys Acta 1998 Feb 5;1390(1):1-7.
2. Expression of brain-type creatine kinase and ubiquitous mitochondrial creatine kinase in the fetal rat brain: evidence for a nuclear energy shuttle. Chen L, etal., J Comp Neurol. 1995 Dec 18;363(3):389-401.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Complete purification of choline kinase from rat kidney and preparation of rabbit antibody against rat kidney choline kinase. Ishidate K, etal., J Biol Chem. 1984 Dec 10;259(23):14706-10.
5. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
6. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. A congenital muscular dystrophy with mitochondrial structural abnormalities caused by defective de novo phosphatidylcholine biosynthesis. Mitsuhashi S, etal., Am J Hum Genet. 2011 Jun 10;88(6):845-51.
9. Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy. Mitsuhashi S, etal., Hum Mol Genet. 2011 Oct 1;20(19):3841-51. Epub 2011 Jul 12.
10. Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Miyagawa T, etal., Nat Genet. 2008 Nov;40(11):1324-8. Epub 2008 Sep 28.
11. Polymorphism located between CPT1B and CHKB, and HLA-DRB1*1501-DQB1*0602 haplotype confer susceptibility to CNS hypersomnias (essential hypersomnia). Miyagawa T, etal., PLoS One. 2009;4(4):e5394. Epub 2009 Apr 30.
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
18. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:15489334   PMID:16371353   PMID:19915674   PMID:22871113  


Genomics

Comparative Map Data
Chkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27120,500,960 - 120,504,359 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7120,500,984 - 120,504,461 (-)Ensembl
Rnor_6.07130,404,818 - 130,408,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,404,832 - 130,408,187 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07130,089,639 - 130,093,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,746,749 - 127,750,104 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17127,780,978 - 127,784,334 (-)NCBI
Celera7116,973,588 - 116,976,943 (-)NCBICelera
RH 3.4 Map7949.5RGD
Cytogenetic Map7q34NCBI
CHKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382250,578,963 - 50,582,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2250,578,959 - 50,601,455 (-)EnsemblGRCh38hg38GRCh38
GRCh372251,017,392 - 51,021,278 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,364,253 - 49,368,260 (-)NCBINCBI36hg18NCBI36
Celera2234,893,420 - 34,897,461 (-)NCBI
Cytogenetic Map22q13.33NCBI
HuRef2233,908,386 - 33,912,427 (-)NCBIHuRef
CHM1_12250,976,120 - 50,980,161 (-)NCBICHM1_1
T2T-CHM13v2.02251,089,491 - 51,093,377 (-)NCBI
Gm44502
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,300,608 - 89,314,130 (-)NCBIGRCm39mm39
GRCm39 Ensembl1589,300,608 - 89,313,899 (-)Ensembl
GRCm381589,416,405 - 89,429,927 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,416,405 - 89,429,696 (-)EnsemblGRCm38mm10GRCm38
MGSCv371589,246,836 - 89,260,127 (-)NCBIGRCm37mm9NCBIm37
Celera1591,545,496 - 91,558,759 (-)NCBICelera
Cytogenetic Map15E3NCBI
Chkb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,310,552 - 89,314,130 (-)NCBIGRCm39mm39
GRCm39 Ensembl1589,310,563 - 89,314,111 (-)Ensembl
GRCm381589,426,349 - 89,429,927 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,426,360 - 89,429,908 (-)EnsemblGRCm38mm10GRCm38
MGSCv371589,256,798 - 89,260,330 (-)NCBIGRCm37mm9NCBIm37
MGSCv361589,254,134 - 89,257,666 (-)NCBImm8
Celera1591,555,430 - 91,558,962 (-)NCBICelera
Cytogenetic Map15E3NCBI
Chkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541333,588,600 - 33,591,758 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541333,588,375 - 33,592,054 (-)NCBIChiLan1.0ChiLan1.0
CHKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12249,936,470 - 49,940,625 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,936,470 - 49,940,625 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02230,825,128 - 30,829,203 (-)NCBIMhudiblu_PPA_v0panPan3
CHKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11016,733,071 - 16,736,797 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1016,733,095 - 16,736,758 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1016,710,701 - 16,714,430 (+)NCBI
ROS_Cfam_1.01017,459,391 - 17,463,120 (+)NCBI
ROS_Cfam_1.0 Ensembl1017,459,328 - 17,463,931 (+)Ensembl
UMICH_Zoey_3.11017,183,779 - 17,187,508 (+)NCBI
UNSW_CanFamBas_1.01017,506,808 - 17,510,537 (+)NCBI
UU_Cfam_GSD_1.01017,638,970 - 17,642,699 (+)NCBI
Chkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945242,891 - 246,731 (+)NCBI
SpeTri2.0NW_004936629242,876 - 246,806 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5151,638 - 155,176 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15151,638 - 155,176 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CHKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11933,055,296 - 33,059,442 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1933,055,294 - 33,059,230 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604592,282,539 - 92,286,806 (+)NCBIVero_WHO_p1.0
Chkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752187,956 - 191,137 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624752187,544 - 191,330 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AU046862  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,505,069 - 120,505,409 (+)MAPPERmRatBN7.2
Rnor_6.07130,408,928 - 130,409,265NCBIRnor6.0
Rnor_5.07130,093,749 - 130,094,086UniSTSRnor5.0
RGSC_v3.47127,750,845 - 127,751,182UniSTSRGSC3.4
Celera7116,977,684 - 116,978,021UniSTS
Cytogenetic Map7q34UniSTS
Chetk  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,501,074 - 120,501,250 (+)MAPPERmRatBN7.2
Rnor_6.07130,404,933 - 130,405,108NCBIRnor6.0
Rnor_5.07130,089,754 - 130,089,929UniSTSRnor5.0
RGSC_v3.47127,746,850 - 127,747,025UniSTSRGSC3.4
Celera7116,973,689 - 116,973,864UniSTS
RH 3.4 Map7949.5UniSTS
Cytogenetic Map7q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7116677010124049952Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)7116677189127103496Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:49
Interacting mature miRNAs:55
Transcripts:ENSRNOT00000015374
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 38 56 40 19 40 1 4 74 35 39 11 1
Low 5 1 1 1 7 7 2 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000015374   ⟹   ENSRNOP00000015374
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7120,500,984 - 120,504,461 (-)Ensembl
Rnor_6.0 Ensembl7130,404,832 - 130,408,187 (-)Ensembl
RefSeq Acc Id: NM_017177   ⟹   NP_058873
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27120,500,974 - 120,504,329 (-)NCBI
Rnor_6.07130,404,832 - 130,408,187 (-)NCBI
Rnor_5.07130,089,639 - 130,093,008 (-)NCBI
RGSC_v3.47127,746,749 - 127,750,104 (-)RGD
Celera7116,973,588 - 116,976,943 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242181   ⟹   XP_006242243
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27120,500,964 - 120,504,359 (-)NCBI
Rnor_6.07130,404,818 - 130,408,813 (-)NCBI
Rnor_5.07130,089,639 - 130,093,008 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765677   ⟹   XP_008763899
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27120,500,964 - 120,504,358 (-)NCBI
Rnor_6.07130,404,830 - 130,408,812 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078574   ⟹   XP_038934502
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27120,500,964 - 120,504,355 (-)NCBI
RefSeq Acc Id: XM_039078575   ⟹   XP_038934503
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27120,500,960 - 120,503,916 (-)NCBI
RefSeq Acc Id: XM_039078576   ⟹   XP_038934504
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27120,500,960 - 120,503,708 (-)NCBI
RefSeq Acc Id: XM_039078577   ⟹   XP_038934505
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27120,500,960 - 120,503,854 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_058873   ⟸   NM_017177
- UniProtKB: O54783 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006242243   ⟸   XM_006242181
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008763899   ⟸   XM_008765677
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000015374   ⟸   ENSRNOT00000015374
RefSeq Acc Id: XP_038934503   ⟸   XM_039078575
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934505   ⟸   XM_039078577
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038934504   ⟸   XM_039078576
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038934502   ⟸   XM_039078574
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54783-F1-model_v2 AlphaFold O54783 1-394 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695589
Promoter ID:EPDNEW_R6113
Type:initiation region
Name:Chkb_1
Description:choline kinase beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07130,408,208 - 130,408,268EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61826 AgrOrtholog
BioCyc Gene G2FUF-32434 BioCyc
BioCyc Pathway PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY3O-450 [phosphatidylcholine biosynthesis I] BioCyc
  PWY4FS-6 [phosphatidylethanolamine biosynthesis II] BioCyc
Ensembl Genes ENSRNOG00000011404 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000015374 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015374 ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5598184 IMAGE-MGC_LOAD
InterPro Cho/Etha_kinase UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:29367 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72507 IMAGE-MGC_LOAD
NCBI Gene 29367 ENTREZGENE
PANTHER PTHR22603:SF35 UniProtKB/Swiss-Prot
PhenoGen Chkb PhenoGen
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
TIGR TC204929
UniProt CHKB_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Chkb  choline kinase beta  Chetk  choline/ethanolamine kinase  Symbol and Name updated 1299863 APPROVED
2002-06-10 Chetk  choline/ethanolamine kinase      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in kidney 61550
gene_protein 394 amino acid predicted protein 61550