(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of KRT8 mRNA] CTD PMID:31150632 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:735537 6480464 o, p'-DDT results in increased expression of KRT8 mRNA CTD PMID:24096037 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression EXP 6480464 o, p'-DDT results in increased expression of KRT8 mRNA CTD PMID:24096037 1,2-dichloroethane increases expression ISO RGD:735537 6480464 ethylene dichloride results in increased expression of KRT8 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions ISO RGD:735537 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KRT8 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression ISO RGD:735537 6480464 1-Naphthylisothiocyanate results in increased expression of KRT8 mRNA CTD PMID:15913567 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of KRT8 mRNA CTD PMID:17522070 more ... 1-naphthyl isothiocyanate multiple interactions ISO RGD:735537 6480464 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1, 2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of KRT8 mRNA] CTD PMID:15913567 17alpha-ethynylestradiol multiple interactions ISO RGD:735537 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT8 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of KRT8 mRNA CTD PMID:29097150 , PMID:30387366 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of KRT8 mRNA CTD PMID:15576828 more ... 17alpha-ethynylestradiol increases expression ISO RGD:735537 6480464 Ethinyl Estradiol results in increased expression of KRT8 mRNA CTD PMID:17942748 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of KRT8 mRNA CTD PMID:17522070 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of KRT8 mRNA CTD PMID:26496021 17beta-estradiol increases expression ISO RGD:735537 6480464 Estradiol results in increased expression of KRT8 mRNA CTD PMID:15289156 , PMID:19484750 17beta-estradiol increases expression ISO RGD:735536 6480464 Estradiol results in increased expression of KRT8 mRNA CTD PMID:14605097 17beta-estradiol decreases expression ISO RGD:735536 6480464 Estradiol results in decreased expression of KRT8 mRNA CTD PMID:16705744 17beta-estradiol multiple interactions ISO RGD:735536 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA more ... CTD PMID:20061804 , PMID:20823114 17beta-estradiol 3-benzoate increases methylation EXP 6480464 estradiol 3-benzoate results in increased methylation of KRT8 promoter CTD PMID:27415467 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:735536 6480464 Metribolone results in increased expression of KRT8 mRNA, Metribolone results in increased expression of KRT8 protein CTD PMID:17010196 , PMID:17152098 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:735536 6480464 Dihydrotestosterone results in increased expression of KRT8 mRNA CTD PMID:29581250 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of KRT8 mRNA CTD PMID:21602191 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735537 6480464 Tetrachlorodibenzodioxin results in increased expression of KRT8 mRNA CTD PMID:17035482 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735537 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT8 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735537 6480464 Tetrachlorodibenzodioxin affects the expression of KRT8 mRNA CTD PMID:12215675 , PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of KRT8 mRNA CTD PMID:20959002 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KRT8 mRNA CTD PMID:21724226 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of KRT8 mRNA CTD PMID:21346803 2-acetamidofluorene multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of KRT8 mRNA, [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of KRT8 mRNA CTD PMID:14656948 , PMID:16158176 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO RGD:735537 6480464 3 more ... CTD PMID:10751352 3,5-diethoxycarbonyl-1,4-dihydrocollidine decreases response to substance ISO RGD:735537 6480464 KRT8 protein results in decreased susceptibility to 3 more ... CTD PMID:10751352 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of KRT8 protein CTD PMID:26597043 4,4'-diaminodiphenylmethane decreases expression ISO RGD:735537 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of KRT8 mRNA CTD PMID:18648102 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of KRT8 mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol increases expression ISO RGD:735537 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of KRT8 mRNA CTD PMID:30951980 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of KRT8 mRNA CTD PMID:21346803 4-hydroxyphenyl retinamide increases expression ISO RGD:735536 6480464 Fenretinide results in increased expression of KRT8 protein CTD PMID:17387344 4-hydroxyphenyl retinamide increases expression ISO RGD:735537 6480464 Fenretinide results in increased expression of KRT8 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine affects expression ISO RGD:735536 6480464 Decitabine affects the expression of KRT8 protein CTD PMID:19294695 5-aza-2'-deoxycytidine multiple interactions ISO RGD:735536 6480464 [trichostatin A co-treated with Decitabine] results in decreased expression of KRT8 protein CTD PMID:19294695 5-azacytidine multiple interactions ISO RGD:735536 6480464 Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA] CTD PMID:20823114 5-azacytidine increases expression ISO RGD:735536 6480464 Azacitidine results in increased expression of KRT8 mRNA CTD PMID:20823114 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of KRT8 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of KRT8 mRNA CTD PMID:19483382 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of KRT8 mRNA CTD PMID:25825206 7,12-dimethyltetraphene multiple interactions EXP 6480464 [9 more ... CTD PMID:22248470 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:22248470 9-cis-retinoic acid increases expression ISO RGD:735536 6480464 Alitretinoin results in increased expression of KRT8 mRNA CTD PMID:17034753 acetamide increases expression EXP 6480464 acetamide results in increased expression of KRT8 mRNA CTD PMID:31881176 acrolein increases metabolic processing ISO RGD:735536 6480464 Acrolein results in increased metabolism of KRT8 protein CTD PMID:20015449 acrolein increases phosphorylation ISO RGD:735536 6480464 Acrolein results in increased phosphorylation of KRT8 protein CTD PMID:24594012 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of KRT8 mRNA CTD PMID:28959563 aflatoxin B1 decreases methylation ISO RGD:735536 6480464 Aflatoxin B1 results in decreased methylation of KRT8 gene CTD PMID:27153756 all-trans-4-oxoretinoic acid increases expression ISO RGD:735536 6480464 4-oxoretinoic acid results in increased expression of KRT8 mRNA CTD PMID:17034753 all-trans-4-oxoretinol increases expression ISO RGD:735536 6480464 4-oxoretinol results in increased expression of KRT8 mRNA CTD PMID:17034753 all-trans-retinoic acid increases expression ISO RGD:735536 6480464 Tretinoin results in increased expression of KRT8 mRNA, Tretinoin results in increased expression of KRT8 protein CTD PMID:17034753 more ... all-trans-retinoic acid multiple interactions ISO RGD:735537 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of KRT8 mRNA CTD PMID:30951980 all-trans-retinoic acid increases expression ISO RGD:735537 6480464 Tretinoin results in increased expression of KRT8 mRNA, Tretinoin results in increased expression of KRT8 protein CTD PMID:16236135 , PMID:7201471 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of KRT8 mRNA CTD PMID:24977338 all-trans-retinol increases expression ISO RGD:735536 6480464 Vitamin A results in increased expression of KRT8 mRNA CTD PMID:17034753 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of KRT8 mRNA CTD PMID:19483382 arachidonic acid multiple interactions ISO RGD:735536 6480464 [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein CTD PMID:17034788 arsane decreases expression ISO RGD:735536 6480464 Arsenic results in decreased expression of KRT8 mRNA CTD PMID:11134558 , PMID:12773770 arsenic atom decreases expression ISO RGD:735536 6480464 Arsenic results in decreased expression of KRT8 mRNA CTD PMID:11134558 , PMID:12773770 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of KRT8 protein CTD PMID:21344382 arsenous acid decreases expression ISO RGD:735536 6480464 Arsenic Trioxide results in decreased expression of KRT8 protein CTD PMID:25419056 arsenous acid decreases response to substance ISO RGD:735536 6480464 KRT8 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of KRT8 mRNA CTD PMID:19483382 benzo[a]pyrene increases expression ISO RGD:735536 6480464 Benzo(a)pyrene results in increased expression of KRT8 mRNA, Benzo(a)pyrene results in increased expression of KRT8 protein CTD PMID:17292933 , PMID:32234424 benzo[a]pyrene decreases methylation ISO RGD:735536 6480464 Benzo(a)pyrene results in decreased methylation of KRT8 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:735537 6480464 Benzo(a)pyrene results in increased expression of KRT8 mRNA CTD PMID:27195522 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of KRT8 protein CTD PMID:16456883 benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [sodium arsenite results in decreased expression of KRT8 protein], sodium arsenite promotes the reaction [Benzo(a)pyrene results in decreased expression of KRT8 protein] CTD PMID:16456883 beta-carotene decreases expression ISO RGD:735536 6480464 beta Carotene results in decreased expression of KRT8 mRNA CTD PMID:17034753 bis(2-ethylhexyl) phthalate increases expression ISO RGD:735536 6480464 Diethylhexyl Phthalate results in increased expression of KRT8 mRNA CTD PMID:31163220 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of KRT8 mRNA CTD PMID:26496021 bisphenol A increases expression ISO RGD:735537 6480464 bisphenol A results in increased expression of KRT8 mRNA CTD PMID:30951980 bisphenol A affects expression ISO RGD:735536 6480464 bisphenol A affects the expression of KRT8 mRNA CTD PMID:30903817 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of KRT8 mRNA CTD PMID:29097150 , PMID:30387366 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of KRT8 mRNA CTD PMID:25181051 bisphenol F multiple interactions ISO RGD:735537 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of KRT8 mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:735537 6480464 bisphenol F results in increased expression of KRT8 mRNA CTD PMID:30951980 bucladesine multiple interactions ISO RGD:735536 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA, Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA] CTD PMID:20823114 Butylparaben increases expression ISO RGD:735536 6480464 butylparaben results in increased expression of KRT8 mRNA CTD PMID:17121429 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of KRT8 mRNA CTD PMID:19167457 cadmium atom decreases response to substance EXP 6480464 KRT8 protein results in decreased susceptibility to Cadmium CTD PMID:17332340 cadmium dichloride increases expression ISO RGD:735536 6480464 Cadmium Chloride results in increased expression of KRT8 protein CTD PMID:26220685 calciol decreases expression ISO RGD:735537 6480464 Cholecalciferol results in decreased expression of KRT8 mRNA CTD PMID:16508948 carbon nanotube affects expression ISO RGD:735536 6480464 Nanotubes, Carbon affects the expression of KRT8 protein CTD PMID:22001959 carbon nanotube increases expression ISO RGD:735537 6480464 Nanotubes, Carbon analog results in increased expression of KRT8 mRNA, Nanotubes, Carbon results in increased expression of KRT8 mRNA CTD PMID:25554681 carbon nanotube decreases expression ISO RGD:735537 6480464 Nanotubes, Carbon analog results in decreased expression of KRT8 mRNA CTD PMID:25620056 carmustine affects response to substance ISO RGD:735536 6480464 KRT8 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 chloroform increases expression EXP 6480464 Chloroform results in increased expression of KRT8 mRNA CTD PMID:17522070 choline multiple interactions ISO RGD:735537 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KRT8 mRNA CTD PMID:20938992 chromium(6+) affects expression ISO RGD:735537 6480464 chromium hexavalent ion affects the expression of KRT8 mRNA CTD PMID:24374135 ciprofibrate increases expression ISO RGD:735537 6480464 ciprofibrate results in increased expression of KRT8 mRNA CTD PMID:12771043 clofibrate multiple interactions ISO RGD:735537 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of KRT8 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of KRT8 mRNA] CTD PMID:17585979 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of KRT8 mRNA CTD PMID:17522070 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of KRT8 mRNA CTD PMID:19483382 cobalt dichloride decreases expression ISO RGD:735536 6480464 cobaltous chloride results in decreased expression of KRT8 mRNA CTD PMID:19376846 copper atom affects binding ISO RGD:735536 6480464 KRT8 protein binds to Copper CTD PMID:14534351 copper atom decreases expression EXP 6480464 Copper results in decreased expression of KRT8 mRNA CTD PMID:30556269 copper(0) affects binding ISO RGD:735536 6480464 KRT8 protein binds to Copper CTD PMID:14534351 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of KRT8 mRNA CTD PMID:30556269 copper(II) sulfate increases expression ISO RGD:735536 6480464 Copper Sulfate results in increased expression of KRT8 mRNA CTD PMID:19549813 cumene multiple interactions ISO RGD:735537 6480464 [cumene co-treated with KRAS gene mutant form] results in decreased expression of KRT8 mRNA CTD PMID:18648096 cyclophosphamide decreases expression ISO RGD:735537 6480464 Cyclophosphamide results in decreased expression of KRT8 mRNA CTD PMID:21621594 cyclosporin A increases expression ISO RGD:735536 6480464 Cyclosporine results in increased expression of KRT8 mRNA CTD PMID:21163907 cytarabine decreases expression ISO RGD:735536 6480464 Cytarabine results in decreased expression of KRT8 mRNA CTD PMID:21198554 daunorubicin increases expression EXP 6480464 Daunorubicin results in increased expression of KRT8 protein CTD PMID:2444108 DDT decreases expression ISO RGD:735536 6480464 DDT results in decreased expression of KRT8 protein CTD PMID:26186133 dexamethasone increases expression ISO RGD:735537 6480464 Dexamethasone results in increased expression of KRT8 mRNA CTD PMID:21621594 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of KRT8 mRNA CTD PMID:17522070 diallyl trisulfide decreases expression ISO RGD:735536 6480464 diallyl trisulfide results in decreased expression of KRT8 protein CTD PMID:16344271 diarsenic trioxide decreases response to substance ISO RGD:735536 6480464 KRT8 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 diarsenic trioxide decreases expression ISO RGD:735536 6480464 Arsenic Trioxide results in decreased expression of KRT8 protein CTD PMID:25419056 dibenz[a,h]anthracene decreases expression ISO RGD:735537 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of KRT8 mRNA CTD PMID:21266533 dichloroacetic acid increases expression ISO RGD:735537 6480464 Dichloroacetic Acid results in increased expression of KRT8 mRNA CTD PMID:28962523 diethylstilbestrol increases expression ISO RGD:735537 6480464 Diethylstilbestrol results in increased expression of KRT8 mRNA CTD PMID:15289156 diethylstilbestrol decreases expression ISO RGD:735537 6480464 Diethylstilbestrol results in decreased expression of KRT8 mRNA CTD PMID:15171707 , PMID:22467019 dimethylarsinic acid increases expression ISO RGD:735537 6480464 Cacodylic Acid results in increased expression of KRT8 mRNA, Cacodylic Acid results in increased expression of KRT8 protein CTD PMID:32052077 dioxygen multiple interactions ISO RGD:735537 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of KRT8 mRNA CTD PMID:30529165 diuron decreases expression EXP 6480464 Diuron results in decreased expression of KRT8 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin affects expression ISO RGD:735536 6480464 Doxorubicin affects the expression of KRT8 protein CTD PMID:29385562 doxorubicin increases expression ISO RGD:735536 6480464 Doxorubicin results in increased expression of KRT8 mRNA CTD PMID:29803840 elemental selenium increases expression ISO RGD:735536 6480464 Selenium results in increased expression of KRT8 mRNA CTD PMID:19244175 entinostat increases expression ISO RGD:735536 6480464 entinostat results in increased expression of KRT8 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA CTD PMID:27188386 ethanol multiple interactions ISO RGD:735536 6480464 [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein CTD PMID:17034788 fenofibrate multiple interactions ISO RGD:735537 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein CTD PMID:18978307 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of KRT8 mRNA CTD PMID:23962444 flavone increases expression ISO RGD:735536 6480464 flavone results in increased expression of KRT8 protein CTD PMID:14750173 flutamide increases expression EXP 6480464 Flutamide results in increased expression of KRT8 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:735537 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 fulvestrant multiple interactions ISO RGD:735536 6480464 KRT8 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]], KRT8 protein promotes the reaction [fulvestrant results in increased degradation of ESR1 protein] CTD PMID:20061804 fumonisin B1 increases expression ISO RGD:735537 6480464 fumonisin B1 results in increased expression of KRT8 mRNA CTD PMID:16221962 furan affects binding EXP 6480464 furan binds to KRT8 protein CTD PMID:22240984 furan increases expression EXP 6480464 furan results in increased expression of KRT8 mRNA CTD PMID:25539665 , PMID:26194646 gemcitabine decreases expression ISO RGD:735536 6480464 gemcitabine results in decreased expression of KRT8 mRNA CTD PMID:17039268 genistein decreases expression ISO RGD:735536 6480464 Genistein results in decreased expression of KRT8 mRNA CTD PMID:16705744 genistein increases expression ISO RGD:735537 6480464 Genistein results in increased expression of KRT8 mRNA CTD PMID:15289156 , PMID:24365114 genistein increases expression ISO RGD:735536 6480464 Genistein results in increased expression of KRT8 protein CTD PMID:20884965 genistein multiple interactions ISO RGD:735536 6480464 ESR1 promotes the reaction [Genistein results in increased expression of KRT8 protein], ESR2 promotes the reaction [Genistein results in increased expression of KRT8 protein] CTD PMID:20884965 griseofulvin increases phosphorylation ISO RGD:735537 6480464 Griseofulvin results in increased phosphorylation of KRT8 protein CTD PMID:20643122 griseofulvin increases expression ISO RGD:735537 6480464 Griseofulvin results in increased expression of KRT8 mRNA, Griseofulvin results in increased expression of KRT8 protein CTD PMID:10952237 more ... hexadecanoic acid decreases phosphorylation ISO RGD:735536 6480464 Palmitic Acid results in decreased phosphorylation of KRT8 protein CTD PMID:28073184 hydrazine increases expression EXP 6480464 hydrazine results in increased expression of KRT8 protein CTD PMID:15370871 iron(III) nitrilotriacetate multiple interactions ISO RGD:735536 6480464 [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein CTD PMID:17034788 isoflavones multiple interactions EXP 6480464 [9 more ... CTD PMID:22248470 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of KRT8 mRNA CTD PMID:19483382 L-methionine multiple interactions ISO RGD:735537 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KRT8 mRNA CTD PMID:20938992 medroxyprogesterone acetate multiple interactions ISO RGD:735536 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA, Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA] CTD PMID:20823114 megestrol acetate increases expression ISO RGD:735536 6480464 Megestrol Acetate results in increased expression of KRT8 protein CTD PMID:16939895 menadione multiple interactions ISO RGD:735536 6480464 Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein], U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein] CTD PMID:15939799 menadione increases phosphorylation ISO RGD:735536 6480464 Vitamin K 3 results in increased phosphorylation of KRT8 protein CTD PMID:15939799 mercury dibromide increases expression ISO RGD:735536 6480464 mercuric bromide results in increased expression of KRT8 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA CTD PMID:27188386 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of KRT8 mRNA CTD PMID:28935588 , PMID:30467583 methapyrilene affects expression EXP 6480464 Methapyrilene affects the expression of KRT8 protein CTD PMID:30467583 methotrexate decreases expression ISO RGD:735537 6480464 Methotrexate results in decreased expression of KRT8 mRNA CTD PMID:21621594 methotrexate decreases expression ISO RGD:735536 6480464 Methotrexate results in decreased expression of KRT8 protein CTD PMID:24736981 methylmercury chloride decreases expression ISO RGD:735536 6480464 methylmercuric chloride results in decreased expression of KRT8 mRNA CTD PMID:23179753 methylmercury chloride increases expression ISO RGD:735536 6480464 methylmercuric chloride results in increased expression of KRT8 mRNA CTD PMID:28001369 methylparaben increases expression ISO RGD:735536 6480464 methylparaben results in increased expression of KRT8 mRNA CTD PMID:17121429 microcystin-LR multiple interactions ISO RGD:735536 6480464 cyanoginosin LR results in increased phosphorylation of and affects the expression of KRT8 protein more ... CTD PMID:22960429 microcystin-LR increases expression ISO RGD:735537 6480464 cyanoginosin LR results in increased expression of KRT8 mRNA CTD PMID:17654400 Monobutylphthalate affects expression ISO RGD:735537 6480464 monobutyl phthalate affects the expression of KRT8 mRNA CTD PMID:19162170 morphine multiple interactions EXP 6480464 Morphine deficiency affects the reaction [Morphine deficiency affects the reaction [Morphine results in decreased expression of KRT8 protein]], Morphine deficiency affects the reaction [Morphine results in decreased expression of KRT8 protein] CTD PMID:23056601 morphine decreases expression EXP 6480464 Morphine results in decreased expression of KRT8 protein CTD PMID:23056601 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:735536 6480464 N more ... CTD PMID:18778698 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:735536 6480464 TP53 mutant form inhibits the reaction [N more ... CTD PMID:18778698 N-acetyl-L-cysteine multiple interactions ISO RGD:735536 6480464 Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein] CTD PMID:15939799 N-butyl-N-(4-hydroxybutyl)nitrosamine decreases expression ISO RGD:735537 6480464 Butylhydroxybutylnitrosamine results in decreased expression of KRT8 protein CTD PMID:24998975 N-nitrosodiethylamine multiple interactions ISO RGD:735537 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT8 protein, [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein CTD PMID:18978307 , PMID:20101389 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of KRT8 mRNA CTD PMID:19638242 N-nitrosodiethylamine increases expression ISO RGD:735537 6480464 Diethylnitrosamine results in increased expression of KRT8 mRNA CTD PMID:12771043 N-nitrosodiethylamine multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of KRT8 mRNA more ... CTD PMID:14656948 more ... N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of KRT8 mRNA CTD PMID:17072980 , PMID:25380136 N-nitrosomorpholine affects expression EXP 6480464 N-nitrosomorpholine affects the expression of KRT8 protein CTD PMID:19716841 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of KRT8 mRNA CTD PMID:24136188 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of KRT8 mRNA CTD PMID:24136188 nystatin increases expression ISO RGD:735537 6480464 Nystatin results in increased expression of KRT8 mRNA CTD PMID:22863853 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of KRT8 mRNA CTD PMID:19483382 orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of KRT8 mRNA CTD PMID:23665939 p-chloromercuribenzoic acid increases expression ISO RGD:735536 6480464 p-Chloromercuribenzoic Acid results in increased expression of KRT8 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA CTD PMID:27188386 panobinostat multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:735536 6480464 panobinostat results in increased expression of KRT8 mRNA CTD PMID:26272509 paracetamol decreases expression ISO RGD:735536 6480464 Acetaminophen results in decreased expression of KRT8 mRNA, Acetaminophen results in decreased expression of KRT8 protein CTD PMID:21420995 , PMID:22230336 paracetamol multiple interactions ISO RGD:735537 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of KRT8 mRNA more ... CTD PMID:17585979 , PMID:25499718 paracetamol affects expression ISO RGD:735537 6480464 Acetaminophen affects the expression of KRT8 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:735536 6480464 Acetaminophen results in increased expression of KRT8 protein CTD PMID:22230336 pentachlorophenol increases expression ISO RGD:735537 6480464 Pentachlorophenol results in increased expression of KRT8 mRNA CTD PMID:23892564 perfluorododecanoic acid increases expression EXP 6480464 perfluorododecanoic acid results in increased expression of KRT8 protein CTD PMID:26168851 perfluorooctane-1-sulfonic acid increases expression ISO RGD:735537 6480464 perfluorooctane sulfonic acid results in increased expression of KRT8 protein CTD PMID:26178269 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of KRT8 mRNA CTD PMID:19162173 phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of and results in increased phosphorylation of KRT8 protein more ... CTD PMID:19409407 , PMID:20935162 phenobarbital increases expression ISO RGD:735537 6480464 Phenobarbital results in increased expression of KRT8 mRNA CTD PMID:19482888 phenobarbital multiple interactions ISO RGD:735537 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of KRT8 mRNA] CTD PMID:19482888 phenobarbital affects expression ISO RGD:735536 6480464 Phenobarbital affects the expression of KRT8 mRNA CTD PMID:19159669 phenylmercury acetate increases expression ISO RGD:735536 6480464 Phenylmercuric Acetate results in increased expression of KRT8 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:735537 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA, [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein CTD PMID:16368122 phosgene affects expression ISO RGD:735537 6480464 Phosgene affects the expression of KRT8 mRNA CTD PMID:16300373 piperonyl butoxide multiple interactions ISO RGD:735537 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT8 protein CTD PMID:20101389 pirinixic acid multiple interactions ISO RGD:735537 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of KRT8 mRNA] CTD PMID:20059764 pirinixic acid increases expression ISO RGD:735537 6480464 pirinixic acid results in increased expression of KRT8 mRNA CTD PMID:16221962 more ... pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of KRT8 mRNA CTD PMID:19483382 prednisolone increases expression ISO RGD:735537 6480464 Prednisolone results in increased expression of KRT8 mRNA CTD PMID:21621594 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of KRT8 mRNA CTD PMID:19162173 progesterone decreases expression ISO RGD:735536 6480464 Progesterone results in decreased expression of KRT8 mRNA CTD PMID:21540246 propiconazole increases expression ISO RGD:735537 6480464 propiconazole results in increased expression of KRT8 mRNA CTD PMID:21278054 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of KRT8 mRNA CTD PMID:17103110 quercetin increases expression ISO RGD:735536 6480464 Quercetin results in increased expression of KRT8 protein CTD PMID:14750173 quercetin decreases expression ISO RGD:735536 6480464 Quercetin results in decreased expression of KRT8 protein CTD PMID:15748282 rac-1,2-dichloropropane multiple interactions ISO RGD:735537 6480464 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of KRT8 protein] CTD PMID:32435916 rac-1,2-dichloropropane decreases expression ISO RGD:735537 6480464 propylene dichloride results in decreased expression of KRT8 protein CTD PMID:32435916 rotenone affects expression EXP 6480464 Rotenone affects the expression of KRT8 mRNA CTD PMID:28374803 SB 203580 multiple interactions ISO RGD:735536 6480464 SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein] CTD PMID:22960429 SB 431542 multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SB 431542 increases expression ISO RGD:735536 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of KRT8 protein CTD PMID:25670856 selenium atom increases expression ISO RGD:735536 6480464 Selenium results in increased expression of KRT8 mRNA CTD PMID:19244175 silicon dioxide affects secretion ISO RGD:735536 6480464 Silicon Dioxide analog affects the secretion of KRT8 protein CTD PMID:25895662 sodium arsenite increases expression ISO RGD:735536 6480464 sodium arsenite results in increased expression of KRT8 mRNA, sodium arsenite results in increased expression of KRT8 protein CTD PMID:12016162 , PMID:19524636 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of KRT8 protein CTD PMID:29459688 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of KRT8 protein CTD PMID:16456883 sodium arsenite multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [sodium arsenite results in decreased expression of KRT8 protein], sodium arsenite promotes the reaction [Benzo(a)pyrene results in decreased expression of KRT8 protein] CTD PMID:16456883 sodium arsenite decreases expression ISO RGD:735536 6480464 sodium arsenite results in decreased expression of KRT8 mRNA CTD PMID:12634122 sodium arsenite increases expression ISO RGD:735537 6480464 sodium arsenite results in increased expression of KRT8 mRNA, sodium arsenite results in increased expression of KRT8 protein CTD PMID:14691202 more ... sodium arsenite multiple interactions ISO RGD:735537 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA, [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein CTD PMID:16368122 sodium arsenite affects expression ISO RGD:735537 6480464 sodium arsenite affects the expression of KRT8 mRNA CTD PMID:16507464 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of KRT8 mRNA CTD PMID:25993096 sodium dodecyl sulfate decreases expression ISO RGD:735537 6480464 Sodium Dodecyl Sulfate results in decreased expression of KRT8 mRNA CTD PMID:21621594 sodium fluoride decreases expression ISO RGD:735537 6480464 Sodium Fluoride results in decreased expression of KRT8 mRNA, Sodium Fluoride results in decreased expression of KRT8 protein CTD PMID:27548804 , PMID:27862939 SU6656 increases expression ISO RGD:735536 6480464 SU 6656 results in increased expression of KRT8 protein CTD PMID:23527294 sulforaphane decreases expression ISO RGD:735536 6480464 sulforafan results in decreased expression of KRT8 mRNA CTD PMID:31838189 sulforaphane increases methylation ISO RGD:735536 6480464 sulforafan results in increased methylation of KRT8 gene CTD PMID:31838189 sunitinib decreases expression ISO RGD:735536 6480464 Sunitinib results in decreased expression of KRT8 mRNA CTD PMID:31533062 T-2 Toxin affects expression EXP 6480464 T-2 Toxin affects the expression of KRT8 protein CTD PMID:26141394 tamoxifen increases expression ISO RGD:735537 6480464 Tamoxifen results in increased expression of KRT8 mRNA CTD PMID:19400957 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of KRT8 mRNA CTD PMID:19400957 temozolomide affects response to substance ISO RGD:735536 6480464 KRT8 mRNA affects the susceptibility to temozolomide CTD PMID:16365179 tetrachloromethane affects expression ISO RGD:735537 6480464 Carbon Tetrachloride affects the expression of KRT8 mRNA CTD PMID:17484886 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of KRT8 mRNA] CTD PMID:31150632 tetrachloromethane increases expression ISO RGD:735537 6480464 Carbon Tetrachloride results in increased expression of KRT8 mRNA CTD PMID:27339419 , PMID:31919559 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of KRT8 mRNA CTD PMID:17522070 , PMID:31150632 tetracycline increases expression EXP 6480464 Tetracycline results in increased expression of KRT8 mRNA CTD PMID:17522070 thapsigargin decreases expression ISO RGD:735536 6480464 Thapsigargin results in decreased expression of KRT8 protein CTD PMID:21692457 theophylline increases expression EXP 6480464 Theophylline results in increased expression of KRT8 mRNA CTD PMID:17522070 thioacetamide multiple interactions ISO RGD:735537 6480464 Thioacetamide results in increased expression of and results in increased phosphorylation of KRT8 protein CTD PMID:18395095 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of KRT8 mRNA CTD PMID:28943392 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of KRT8 mRNA CTD PMID:23411599 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of KRT8 mRNA CTD PMID:19483382 thioacetamide increases expression ISO RGD:735537 6480464 Thioacetamide results in increased expression of KRT8 mRNA CTD PMID:18395095 titanium dioxide increases expression ISO RGD:735537 6480464 titanium dioxide results in increased expression of KRT8 mRNA CTD PMID:23409001 , PMID:27760801 titanium dioxide decreases expression ISO RGD:735537 6480464 titanium dioxide results in decreased expression of KRT8 mRNA CTD PMID:23557971 trichostatin A affects expression ISO RGD:735536 6480464 trichostatin A affects the expression of KRT8 protein CTD PMID:19294695 trichostatin A increases expression ISO RGD:735536 6480464 trichostatin A results in increased expression of KRT8 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:19294695 , PMID:27188386 troglitazone decreases expression ISO RGD:735536 6480464 troglitazone results in decreased expression of KRT8 mRNA CTD PMID:19140230 tunicamycin increases expression ISO RGD:735536 6480464 Tunicamycin results in increased expression of KRT8 mRNA CTD PMID:29453283 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of KRT8 mRNA CTD PMID:24136188 valproic acid increases expression ISO RGD:735537 6480464 Valproic Acid results in increased expression of KRT8 mRNA CTD PMID:19136453 valproic acid multiple interactions ISO RGD:735536 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:735536 6480464 Valproic Acid results in increased expression of KRT8 mRNA CTD PMID:23179753 more ... vancomycin decreases expression ISO RGD:735537 6480464 Vancomycin results in decreased expression of KRT8 mRNA CTD PMID:18930951 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of KRT8 mRNA CTD PMID:19015723 zinc atom increases expression ISO RGD:735537 6480464 Zinc deficiency results in increased expression of KRT8 mRNA CTD PMID:20857495 zinc(0) increases expression ISO RGD:735537 6480464 Zinc deficiency results in increased expression of KRT8 mRNA CTD PMID:20857495 zoledronic acid decreases expression ISO RGD:735536 6480464 zoledronic acid results in decreased expression of KRT8 mRNA CTD PMID:24714768
Gene-Chemical Interaction Annotations
