Pycr3 (pyrroline-5-carboxylate reductase 3) - Rat Genome Database

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Gene: Pycr3 (pyrroline-5-carboxylate reductase 3) Rattus norvegicus
Analyze
Symbol: Pycr3
Name: pyrroline-5-carboxylate reductase 3
RGD ID: 1309115
Description: Predicted to enable identical protein binding activity and pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Predicted to be located in cytosol; intercellular bridge; and mitotic spindle. Orthologous to human PYCR3 (pyrroline-5-carboxylate reductase 3); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; astemizole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC300035; P5C reductase 3; P5CR 3; Pycrl; pyrroline-5-carboxylate reductase-like; pyrroline-5-carboxylate reductase-like protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27107,603,543 - 107,608,831 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7107,581,930 - 107,608,799 (-)Ensembl
Rnor_6.07116,949,882 - 116,955,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,949,879 - 116,955,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,842,453 - 116,847,953 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,895,788 - 113,926,200 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17113,930,019 - 113,960,430 (-)NCBI
Celera7103,960,547 - 103,965,815 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2722838   PMID:11591653   PMID:12477932   PMID:23024808  


Genomics

Comparative Map Data
Pycr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27107,603,543 - 107,608,831 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7107,581,930 - 107,608,799 (-)Ensembl
Rnor_6.07116,949,882 - 116,955,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,949,879 - 116,955,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,842,453 - 116,847,953 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,895,788 - 113,926,200 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17113,930,019 - 113,960,430 (-)NCBI
Celera7103,960,547 - 103,965,815 (-)NCBICelera
Cytogenetic Map7q34NCBI
PYCR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,603,210 - 143,609,575 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8143,603,210 - 143,609,773 (-)EnsemblGRCh38hg38GRCh38
GRCh378144,685,380 - 144,691,745 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,757,532 - 144,762,887 (-)NCBINCBI36hg18NCBI36
Build 348144,757,531 - 144,762,887NCBI
Celera8140,996,326 - 141,002,023 (-)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8139,937,358 - 139,943,055 (-)NCBIHuRef
CHM1_18144,726,322 - 144,732,023 (-)NCBICHM1_1
T2T-CHM13v2.08144,752,622 - 144,758,991 (-)NCBI
Pycrl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,788,312 - 75,793,409 (-)NCBIGRCm39mm39
GRCm39 Ensembl1575,788,326 - 75,793,409 (-)Ensembl
GRCm381575,916,463 - 75,921,560 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,916,477 - 75,921,560 (-)EnsemblGRCm38mm10GRCm38
MGSCv371575,746,893 - 75,751,990 (-)NCBIGRCm37mm9NCBIm37
MGSCv361575,743,732 - 75,748,815 (-)NCBImm8
Celera1577,417,474 - 77,422,576 (-)NCBICelera
Cytogenetic Map15D3NCBI
Pycr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,305,485 - 2,311,280 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,305,485 - 2,311,280 (-)NCBIChiLan1.0ChiLan1.0
PYCR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18143,372,465 - 143,378,032 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8143,371,748 - 143,378,032 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08140,356,586 - 140,362,972 (-)NCBIMhudiblu_PPA_v0panPan3
PYCR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,259,139 - 37,264,337 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,259,139 - 37,264,337 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,215,627 - 37,220,822 (-)NCBI
ROS_Cfam_1.01337,730,959 - 37,736,154 (-)NCBI
ROS_Cfam_1.0 Ensembl1337,730,962 - 37,736,140 (-)Ensembl
UMICH_Zoey_3.11337,405,229 - 37,410,424 (-)NCBI
UNSW_CanFamBas_1.01337,522,197 - 37,527,386 (-)NCBI
UU_Cfam_GSD_1.01338,003,432 - 38,008,627 (-)NCBI
Pycr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,101,848 - 1,105,689 (+)NCBI
SpeTri2.0NW_0049364708,527,896 - 8,531,788 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PYCR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4959,710 - 964,192 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14959,709 - 964,195 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.241,012,808 - 1,014,006 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PYCR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,823,685 - 137,830,630 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,826,293 - 137,830,546 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660392,062,896 - 2,068,829 (+)NCBIVero_WHO_p1.0
Pycr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473513,136,287 - 13,142,051 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH134115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27107,603,551 - 107,603,743 (+)MAPPERmRatBN7.2
Rnor_6.07116,949,885 - 116,950,076NCBIRnor6.0
Rnor_5.07116,842,456 - 116,842,647UniSTSRnor5.0
RGSC_v3.47113,895,791 - 113,895,982UniSTSRGSC3.4
Celera7103,960,550 - 103,960,741UniSTS
RH 3.4 Map7785.1UniSTS
Cytogenetic Map7q34UniSTS
AI169002  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27107,603,830 - 107,604,010 (+)MAPPERmRatBN7.2
Rnor_6.07116,950,164 - 116,950,343NCBIRnor6.0
Rnor_5.07116,842,735 - 116,842,914UniSTSRnor5.0
RGSC_v3.47113,896,070 - 113,896,249UniSTSRGSC3.4
Celera7103,960,829 - 103,961,008UniSTS
Cytogenetic Map7q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 7 10 74 35 36 11 7
Low 6 1 1 5 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000087328   ⟹   ENSRNOP00000071183
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,949,879 - 116,955,148 (-)Ensembl
RefSeq Acc Id: NM_001011993   ⟹   NP_001011993
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27107,603,549 - 107,608,817 (-)NCBI
Rnor_6.07116,949,882 - 116,955,150 (-)NCBI
Rnor_5.07116,842,453 - 116,847,953 (-)NCBI
RGSC_v3.47113,895,788 - 113,926,200 (-)RGD
Celera7103,960,547 - 103,965,815 (-)RGD
Sequence:
RefSeq Acc Id: XM_039078820   ⟹   XP_038934748
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27107,603,543 - 107,608,831 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001011993 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934748 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87166 (Get FASTA)   NCBI Sequence Viewer  
  EDM16035 (Get FASTA)   NCBI Sequence Viewer  
  Q5PQJ6 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001011993   ⟸   NM_001011993
- UniProtKB: Q5PQJ6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071183   ⟸   ENSRNOT00000087328
RefSeq Acc Id: XP_038934748   ⟸   XM_039078820
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PQJ6-F1-model_v2 AlphaFold Q5PQJ6 1-274 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695395
Promoter ID:EPDNEW_R5919
Type:initiation region
Name:Pycr3_1
Description:pyrroline-5-carboxylate reductase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07116,955,111 - 116,955,171EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309115 AgrOrtholog
BioCyc Gene G2FUF-32974 BioCyc
BioCyc Pathway ARG-PRO-PWY [L-arginine degradation VI (arginase 2 pathway)] BioCyc
Ensembl Genes ENSRNOG00000021638 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000054724 Ensembl
Ensembl Protein ENSRNOP00000034828.5 UniProtKB/TrEMBL
  ENSRNOP00000071183 ENTREZGENE
  ENSRNOP00000071183.2 UniProtKB/TrEMBL
  ENSRNOP00000076544.1 UniProtKB/TrEMBL
  ENSRNOP00000081329.1 UniProtKB/TrEMBL
  ENSRNOP00000084037.1 UniProtKB/TrEMBL
  ENSRNOP00000087171.1 UniProtKB/TrEMBL
  ENSRNOP00000092090.1 UniProtKB/TrEMBL
  ENSRNOP00000096307.1 UniProtKB/TrEMBL
  ENSRNOP00000097149.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029456.6 UniProtKB/TrEMBL
  ENSRNOT00000087328 ENTREZGENE
  ENSRNOT00000087328.2 UniProtKB/TrEMBL
  ENSRNOT00000094330.1 UniProtKB/TrEMBL
  ENSRNOT00000098616.1 UniProtKB/TrEMBL
  ENSRNOT00000106771.1 UniProtKB/TrEMBL
  ENSRNOT00000110570.1 UniProtKB/TrEMBL
  ENSRNOT00000111979.1 UniProtKB/TrEMBL
  ENSRNOT00000112184.1 UniProtKB/TrEMBL
  ENSRNOT00000117537.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.60 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135468 IMAGE-MGC_LOAD
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  eEF-1beta-like_sf UniProtKB/TrEMBL
  EF-1_beta_acid_region_euk UniProtKB/TrEMBL
  EF1B_bsu/dsu_GNE UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P5C_Rdtase_cat_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P5CR_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pyrroline-COOH_reductase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EF1B/ribosomal_S6 UniProtKB/TrEMBL
  Transl_elong_EF1B_B/D_CS UniProtKB/TrEMBL
KEGG Report rno:300035 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95331 IMAGE-MGC_LOAD
NCBI Gene 300035 ENTREZGENE
PANTHER PTHR11645 UniProtKB/Swiss-Prot
Pfam EF-1_beta_acid UniProtKB/TrEMBL
  EF1_GNE UniProtKB/TrEMBL
  F420_oxidored UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P5CR_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pycr3 PhenoGen
PIRSF Pyrrol-5-carb_rd UniProtKB/Swiss-Prot
PROSITE EF1BD_2 UniProtKB/TrEMBL
SMART EF-1_beta_acid UniProtKB/TrEMBL
  EF1_GNE UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54984 UniProtKB/TrEMBL
TIGRFAMs proC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y6S6_RAT UniProtKB/TrEMBL
  A0A8I5ZUU1_RAT UniProtKB/TrEMBL
  A0A8I5ZWY7_RAT UniProtKB/TrEMBL
  A0A8I6AQM3_RAT UniProtKB/TrEMBL
  A0A8I6ARB5_RAT UniProtKB/TrEMBL
  A0A8I6GFR4_RAT UniProtKB/TrEMBL
  A0A8I6GJH3_RAT UniProtKB/TrEMBL
  A0A8L2QI22_RAT UniProtKB/TrEMBL
  A0A8L2UQA6_RAT UniProtKB/TrEMBL
  P5CR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-29 Pycr3  pyrroline-5-carboxylate reductase 3  Pycrl  pyrroline-5-carboxylate reductase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pycrl  pyrroline-5-carboxylate reductase-like  Pycrl_predicted  pyrroline-5-carboxylate reductase-like (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pycrl_predicted  pyrroline-5-carboxylate reductase-like (predicted)      Symbol and Name status set to approved 70820 APPROVED