Tst (thiosulfate sulfurtransferase) - Rat Genome Database

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Gene: Tst (thiosulfate sulfurtransferase) Rattus norvegicus
Analyze
Symbol: Tst
Name: thiosulfate sulfurtransferase
RGD ID: 3913
Description: Predicted to enable 3-mercaptopyruvate sulfurtransferase activity; 5S rRNA binding activity; and thiosulfate sulfurtransferase activity. Predicted to be involved in epithelial cell differentiation and rRNA import into mitochondrion. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human TST (thiosulfate sulfurtransferase); PARTICIPATES IN cysteine and methionine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: RHODAN; rhodanese; thiosulfate sulfurtransferase, mitochondrial; Thiosulfate sulphurtransferase (rhodanese)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,828,557 - 111,836,980 (-)NCBIGRCr8
mRatBN7.27109,948,061 - 109,955,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,948,062 - 109,957,216 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,697,709 - 111,704,460 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07113,921,242 - 113,927,993 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07113,889,944 - 113,896,691 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,616,323 - 119,623,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,616,324 - 119,623,072 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,606,998 - 119,613,747 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,349,579 - 116,355,921 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,383,866 - 116,390,114 (-)NCBI
Celera7106,286,095 - 106,292,845 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fumonisin B1  (ISO)
hydralazine  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
manganese(II) chloride  (EXP)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methapyrilene  (EXP,ISO)
methidathion  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-nitrosomorpholine  (EXP)
nickel dichloride  (ISO)
nitrofen  (EXP)
Nutlin-3  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctanoic acid  (ISO)
picoxystrobin  (ISO)
potassium cyanide  (ISO)
propiconazole  (EXP)
Propiverine  (EXP)
pyrimidifen  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
XL147  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrial matrix  (IEA,TAS)
mitochondrion  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
9. Molecular cloning, sequencing and characterization of cDNA to rat liver rhodanese, a thiosulphate sulphurtransferase. Weiland KL and Dooley TP, Biochem J 1991 Apr 1;275 ( Pt 1):227-31.
Additional References at PubMed
PMID:7608189   PMID:12477932   PMID:12865426   PMID:14651853   PMID:15489334   PMID:18614015   PMID:20663881   PMID:21492153   PMID:21685364   PMID:23376485   PMID:23580065  


Genomics

Comparative Map Data
Tst
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,828,557 - 111,836,980 (-)NCBIGRCr8
mRatBN7.27109,948,061 - 109,955,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,948,062 - 109,957,216 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,697,709 - 111,704,460 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07113,921,242 - 113,927,993 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07113,889,944 - 113,896,691 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,616,323 - 119,623,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,616,324 - 119,623,072 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,606,998 - 119,613,747 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,349,579 - 116,355,921 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,383,866 - 116,390,114 (-)NCBI
Celera7106,286,095 - 106,292,845 (-)NCBICelera
Cytogenetic Map7q34NCBI
TST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,010,859 - 37,020,183 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,010,859 - 37,020,183 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,406,900 - 37,416,224 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,736,852 - 35,745,437 (-)NCBINCBI36Build 36hg18NCBI36
Build 342235,731,406 - 35,739,991NCBI
Celera2221,208,242 - 21,216,827 (-)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2220,372,028 - 20,390,853 (-)NCBIHuRef
CHM1_12237,366,379 - 37,375,716 (-)NCBICHM1_1
T2T-CHM13v2.02237,470,450 - 37,479,782 (-)NCBIT2T-CHM13v2.0
Tst
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,283,756 - 78,290,065 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,283,756 - 78,290,107 (-)EnsemblGRCm39 Ensembl
GRCm381578,399,556 - 78,405,865 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,399,556 - 78,405,907 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,229,986 - 78,236,289 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,226,811 - 78,233,117 (-)NCBIMGSCv36mm8
Celera1579,862,256 - 79,868,553 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.47NCBI
Tst
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,528,417 - 23,534,979 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,528,468 - 23,534,890 (-)NCBIChiLan1.0ChiLan1.0
TST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22346,867,782 - 46,876,495 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12249,556,361 - 49,565,060 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02217,925,215 - 17,933,919 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12235,761,073 - 35,769,651 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,761,073 - 35,768,992 (-)Ensemblpanpan1.1panPan2
TST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,474,101 - 27,486,603 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,473,764 - 27,486,575 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,427,965 - 27,441,111 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01028,265,478 - 28,278,615 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1028,266,267 - 28,278,613 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,987,062 - 28,000,182 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01028,295,640 - 28,308,756 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,473,581 - 28,486,734 (+)NCBIUU_Cfam_GSD_1.0
Tst
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,870,086 - 10,876,466 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,880,500 - 3,886,950 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,880,545 - 3,886,881 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,746,890 - 10,759,622 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,749,264 - 10,759,623 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.258,348,614 - 8,358,974 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11919,716,295 - 19,724,712 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1919,716,180 - 19,724,589 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045106,137,782 - 106,146,330 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tst
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,765,137 - 10,774,800 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,765,126 - 10,772,159 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tst
49 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:34
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000050511
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
AW553467  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27109,948,305 - 109,948,431 (+)MAPPERmRatBN7.2
Rnor_6.07119,616,565 - 119,616,690NCBIRnor6.0
Rnor_5.07119,607,240 - 119,607,365UniSTSRnor5.0
RGSC_v3.47116,349,821 - 116,349,946UniSTSRGSC3.4
Celera7106,286,337 - 106,286,462UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC088449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000050511   ⟹   ENSRNOP00000039338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7109,948,062 - 109,957,216 (-)Ensembl
Rnor_6.0 Ensembl7119,616,324 - 119,623,072 (-)Ensembl
RefSeq Acc Id: NM_012808   ⟹   NP_036940
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87111,828,560 - 111,835,309 (-)NCBI
mRatBN7.27109,948,064 - 109,954,813 (-)NCBI
Rnor_6.07119,616,323 - 119,623,072 (-)NCBI
Rnor_5.07119,606,998 - 119,613,747 (-)NCBI
RGSC_v3.47116,349,579 - 116,355,921 (-)RGD
Celera7106,286,095 - 106,292,845 (-)RGD
Sequence:
RefSeq Acc Id: XM_063263012   ⟹   XP_063119082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87111,828,557 - 111,836,980 (-)NCBI
RefSeq Acc Id: XM_063263013   ⟹   XP_063119083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87111,828,557 - 111,836,135 (-)NCBI
RefSeq Acc Id: NP_036940   ⟸   NM_012808
- UniProtKB: Q5I0D4 (UniProtKB/Swiss-Prot),   P24329 (UniProtKB/Swiss-Prot),   A6HSJ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039338   ⟸   ENSRNOT00000050511
RefSeq Acc Id: XP_063119082   ⟸   XM_063263012
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QJT5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119083   ⟸   XM_063263013
- Peptide Label: isoform X2
- UniProtKB: Q5I0D4 (UniProtKB/Swiss-Prot),   P24329 (UniProtKB/Swiss-Prot),   A6HSJ7 (UniProtKB/TrEMBL)
Protein Domains
Rhodanese

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P24329-F1-model_v2 AlphaFold P24329 1-297 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695459
Promoter ID:EPDNEW_R5984
Type:initiation region
Name:Tst_1
Description:thiosulfate sulfurtransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07119,623,073 - 119,623,133EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3913 AgrOrtholog
BioCyc Gene G2FUF-32828 BioCyc
BioCyc Pathway PWY-5350 [thiosulfate disproportionation IV (rhodanese)] BioCyc
  PWY-7927 [sulfide oxidation IV (mitochondria)] BioCyc
BioCyc Pathway Image PWY-5350 BioCyc
  PWY-7927 BioCyc
Ensembl Genes ENSRNOG00000000186 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050511.6 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7126617 IMAGE-MGC_LOAD
InterPro Rhodanese-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thiosulphate_STrfase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TST/MPST-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25274 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:95094 IMAGE-MGC_LOAD
NCBI Gene 25274 ENTREZGENE
PANTHER PTHR11364 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THIOSULFATE SULFURTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Rhodanese UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tst PhenoGen
PROSITE RHODANESE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHODANESE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHODANESE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000186 RatGTEx
SMART RHOD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52821 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217570
UniProt A0A8L2QJT5 ENTREZGENE, UniProtKB/TrEMBL
  A6HSJ6_RAT UniProtKB/TrEMBL
  A6HSJ7 ENTREZGENE, UniProtKB/TrEMBL
  P24329 ENTREZGENE
  Q5I0D4 ENTREZGENE
  THTR_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q5I0D4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-02-19 Tst  thiosulfate sulfurtransferase  Tst  thiosulfate sulfurtransferase, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Tst  thiosulfate sulfurtransferase, mitochondrial  Tst  thiosulfate sulfurtransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Tst  thiosulfate sulfurtransferase    Thiosulfate sulphurtransferase (rhodanese)  Name updated 629478 APPROVED
2002-06-10 Tst  Thiosulfate sulphurtransferase (rhodanese)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_evolution DNA sequence appears to be highly conserved among bovines, rodents and primates 729953
gene_homology aa sequence shares 91% identity with bovine Tst 729953