Gene: Nr4a1 (nuclear receptor subfamily 4, group A, member 1) Rattus norvegicus
Symbol: Nr4a1
Name: nuclear receptor subfamily 4, group A, member 1
Description: ENCODES a protein that exhibits glucocorticoid receptor binding; protein heterodimerization activity; proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific; INVOLVED IN positive regulation of transcription by RNA polymerase II; regulation of type B pancreatic cell proliferation; apoptotic process (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH abnormal renal glomerular filtration; albuminuria; ASSOCIATED WITH blood pressure trait; blood urea nitrogen amount; cholesterol amount; FOUND IN nucleus; cytosol (ortholog); nuclear membrane (ortholog); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HMR; immediate early gene transcription factor NGFI-B; nerve growth factor induced protein I-B; nerve growth factor-induced protein I-B; Ngfi-b; nuclear receptor subfamily 4 group A member 1; Nur77; Orphan nuclear receptor HMR
Homo sapiens (human) : NR4A1 (nuclear receptor subfamily 4 group A member 1)  HGNC  Alliance
Mus musculus (house mouse) : Nr4a1 (nuclear receptor subfamily 4, group A, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Canis lupus familiaris (dog) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
more info ...
Allele / Splice: Nr4a1m1Mcwi  
Genetic Models: FHH-Nr4a1m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07142,899,358 - 142,920,216 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07140,700,242 - 140,721,073 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,012,807 - 140,020,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,089,243 - 140,097,024 (+)NCBI
Celera7128,846,928 - 128,854,640 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
Experimental Data Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Nr4a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620029
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE