Krt6a (keratin 6A) - Rat Genome Database

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Gene: Krt6a (keratin 6A) Rattus norvegicus
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Symbol: Krt6a
Name: keratin 6A
RGD ID: 41330462
Description: INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cytolysis by host of symbiont cells (ortholog); defense response to Gram-positive bacterium (ortholog); ASSOCIATED WITH pachyonychia congenita (ortholog); Pachyonychia Congenita 3 (ortholog); INTERACTS WITH N-nitrosomorpholine; 1-chloro-2,4-dinitrobenzene (ortholog); 17beta-estradiol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: keratin, type II cytoskeletal 6A
RGD Orthologs
Human
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27132,829,278 - 132,833,665 (-)NCBImRatBN7.2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
Krt6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27132,829,278 - 132,833,665 (-)NCBImRatBN7.2
KRT6A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1252,487,176 - 52,493,257 (-)EnsemblGRCh38hg38GRCh38
GRCh381252,487,176 - 52,493,257 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371252,880,960 - 52,887,041 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,167,225 - 51,173,448 (-)NCBINCBI36hg18NCBI36
Build 341251,167,243 - 51,173,287NCBI
Celera1252,527,198 - 52,533,425 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1249,924,865 - 49,931,092 (-)NCBIHuRef
CHM1_11252,847,818 - 52,854,045 (-)NCBICHM1_1
Krt6a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555472,902,962 - 2,907,670 (-)NCBIChiLan1.0ChiLan1.0
KRT6A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11237,048,390 - 37,054,607 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1237,048,390 - 37,054,607 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01236,270,961 - 36,277,035 (+)NCBIMhudiblu_PPA_v0panPan3
LOC486523
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,609,414 - 2,623,810 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2743,630,209 - 43,644,448 (-)NCBI
ROS_Cfam_1.0272,607,992 - 2,613,493 (+)NCBI
UMICH_Zoey_3.1272,625,515 - 2,631,019 (+)NCBI
UNSW_CanFamBas_1.0272,610,753 - 2,625,394 (+)NCBI
UU_Cfam_GSD_1.02744,028,444 - 44,042,667 (-)NCBI
Krt6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494563,256,954 - 63,261,682 (+)NCBI
SpeTri2.0NW_0049365129,903,206 - 9,908,009 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103238356
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11148,636,023 - 48,643,854 (-)NCBI
ChlSab1.1 Ensembl1148,636,573 - 48,642,096 (-)Ensembl
Vero_WHO_p1.0NW_0236670107 - 5,553 (-)NCBI
Krt6a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624904631,684 - 639,693 (-)NCBI


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_039080392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_039080392   ⟹   XP_038936320
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27132,829,278 - 132,833,665 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038936320 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_038936320   ⟸   XM_039080392


Additional Information

Database Acc Id Source(s)
NCBI Gene Krt6a ENTREZGENE
PhenoGen Krt6a PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-27 Krt6a  keratin 6A      Symbol and Name status set to provisional 70820 PROVISIONAL