Pde1b (phosphodiesterase 1B) - Rat Genome Database

Name: Pde1b
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Pde1b (phosphodiesterase 1B) Rattus norvegicus

Analyze

Symbol:

Pde1b

Name:

phosphodiesterase 1B

RGD ID:

3278

Description:

Enables 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in cellular response to cytokine stimulus; monocyte differentiation; and signal transduction. Predicted to act upstream of or within several processes, including response to amphetamine; serotonin metabolic process; and visual learning. Located in neuronal cell body. Biomarker of Parkinsonism. Orthologous to human PDE1B (phosphodiesterase 1B); PARTICIPATES IN protein kinase A (PKA) signaling pathway; calcium/calcium-mediated signaling pathway; purine metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; C60 fullerene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Pde1b1; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; phosphodiesterase IB, calmodulin-dependent

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PDE1B (phosphodiesterase 1B)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pde1b (phosphodiesterase 1B, Ca2+-calmodulin dependent)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pde1b (phosphodiesterase 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PDE1B (phosphodiesterase 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PDE1B (phosphodiesterase 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pde1b (phosphodiesterase 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PDE1B (phosphodiesterase 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PDE1B (phosphodiesterase 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pde1b (phosphodiesterase 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PDE1C (phosphodiesterase 1C)	HGNC	PhylomeDB
Alliance orthologs ³
Homo sapiens (human):	PDE1B (phosphodiesterase 1B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pde1b (phosphodiesterase 1B, Ca2+-calmodulin dependent)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PDE2	Alliance	DIOPT (Ensembl Compara\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Pde1c	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pde-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pde1b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	134,627,378 - 134,654,581 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	134,627,322 - 134,654,580 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	136,382,888 - 136,409,313 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	7	138,612,263 - 138,638,684 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	7	138,598,329 - 138,624,285 (+)	NCBI	Rnor_WKY
Rnor_6.0	7	145,117,951 - 145,147,711 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	145,117,951 - 145,145,376 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	142,899,029 - 142,925,733 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	142,401,489 - 142,427,626 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	142,481,677 - 142,507,815 (+)	NCBI
Celera	7	131,051,310 - 131,077,552 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

learning disability (ISO)

Parkinsonism (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

C60 fullerene (EXP)

CGP 52608 (ISO)

choline (ISO)

clofibrate (ISO)

clozapine (ISO)

colforsin daropate hydrochloride (ISO)

copper atom (EXP)

copper(0) (EXP)

cytarabine (ISO)

disodium selenite (ISO)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

haloperidol (EXP,ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

maneb (ISO)

melatonin (ISO)

methamphetamine (ISO)

methotrexate (ISO)

nitrofen (EXP)

p-menthan-3-ol (ISO)

paracetamol (ISO)

paraquat (ISO)

phorbol 13-acetate 12-myristate (ISO)

pirinixic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

trichloroethene (EXP)

triclosan (ISO)

trovafloxacin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to granulocyte macrophage colony-stimulating factor stimulus (ISO)

cellular response to macrophage colony-stimulating factor stimulus (ISO)

locomotory behavior (ISO)

monocyte differentiation (ISO)

regulation of dopamine metabolic process (ISO)

regulation of neurotransmitter levels (ISO)

response to amphetamine (ISO)

serotonin metabolic process (ISO)

signal transduction (IBA,IEA,ISO)

visual learning (ISO)

Cellular Component

cytosol (ISO,ISS)

neuronal cell body (IBA,IDA)

Molecular Function

3',5'-cyclic-AMP phosphodiesterase activity (IDA,ISO)

3',5'-cyclic-GMP phosphodiesterase activity (ISO)

3',5'-cyclic-nucleotide phosphodiesterase activity (IEA)

calmodulin binding (IEA)

calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity (IBA)

calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity (ISO,ISS)

cyclic-nucleotide phosphodiesterase activity (IDA)

metal ion binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (IEA)

protein kinase A (PKA) signaling pathway (ISO)

purine metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling.	Conti M and Beavo J, Annu Rev Biochem. 2007;76:481-511.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase.	Repaske DR, etal., J Biol Chem 1992 Sep 15;267(26):18683-8.
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Down-regulation of nitrergic transmission in the rat striatum after chronic nigrostriatal deafferentation.	Sancesario G, etal., Eur J Neurosci. 2004 Aug;20(4):989-1000.
12.	Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina.	Santone R, etal., J Neurosci Res. 2006 Oct;84(5):1020-6.

Additional References at PubMed

PMID:12077213	PMID:14687666	PMID:17010100	PMID:17559891	PMID:19292454	PMID:33444639

Genomics

Comparative Map Data

Pde1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	134,627,378 - 134,654,581 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	134,627,322 - 134,654,580 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	136,382,888 - 136,409,313 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	7	138,612,263 - 138,638,684 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	7	138,598,329 - 138,624,285 (+)	NCBI	Rnor_WKY
Rnor_6.0	7	145,117,951 - 145,147,711 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	145,117,951 - 145,145,376 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	142,899,029 - 142,925,733 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	142,401,489 - 142,427,626 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	142,481,677 - 142,507,815 (+)	NCBI
Celera	7	131,051,310 - 131,077,552 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

PDE1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	54,549,601 - 54,579,239 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	12	54,549,601 - 54,579,239 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	54,943,385 - 54,973,023 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	53,229,671 - 53,259,290 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	53,229,670 - 53,259,290	NCBI
Celera	12	54,595,042 - 54,624,893 (+)	NCBI		Celera
Cytogenetic Map	12	q13.2	NCBI
HuRef	12	51,981,948 - 52,011,831 (+)	NCBI		HuRef
CHM1_1	12	54,909,885 - 54,939,730 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	54,516,175 - 54,545,790 (+)	NCBI		T2T-CHM13v2.0

Pde1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	103,411,461 - 103,438,483 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	103,411,461 - 103,438,479 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	103,503,034 - 103,530,056 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	103,503,034 - 103,530,052 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	103,333,729 - 103,360,483 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	103,331,333 - 103,358,086 (+)	NCBI		MGSCv36	mm8
Celera	15	105,661,285 - 105,688,050 (+)	NCBI		Celera
Cytogenetic Map	15	F3	NCBI

Pde1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	1,791,090 - 1,821,813 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955458	1,791,090 - 1,819,261 (+)	NCBI	ChiLan1.0	ChiLan1.0

PDE1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	12	39,592,337 - 39,622,028 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	34,167,801 - 34,198,049 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	34,896,362 - 34,926,223 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

PDE1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	772,741 - 800,967 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	772,056 - 800,375 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	45,453,293 - 45,480,837 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	771,740 - 798,788 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	771,072 - 798,938 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	763,412 - 791,180 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	771,568 - 799,618 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	45,857,507 - 45,884,981 (+)	NCBI		UU_Cfam_GSD_1.0

Pde1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	61,398,566 - 61,425,617 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	11,739,213 - 11,768,190 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936512	11,739,219 - 11,766,264 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDE1B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	19,725,415 - 19,752,888 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	19,725,346 - 19,752,892 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	20,582,610 - 20,612,210 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PDE1B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	50,664,801 - 50,694,887 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	50,664,844 - 50,692,971 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	195,341,788 - 195,371,575 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pde1b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624904	2,580,322 - 2,607,961 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624904	2,580,055 - 2,607,961 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pde1b
88 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	181
Count of miRNA genes:	114
Interacting mature miRNAs:	143
Transcripts:	ENSRNOT00000055272
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	91281130	135012528	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	96670164	135012528	Rat
731174	Uae23	Urinary albumin excretion QTL 23	2.4	0.0042	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	7	104603555	135012528	Rat
2306821	Bp335	Blood pressure QTL 335		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	106571501	135012528	Rat
631663	Bw6	Body weight QTL 6	3.4		body mass (VT:0001259)	body weight (CMO:0000012)	7	111075573	134976056	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	111182207	135012528	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	119513385	135012528	Rat

Markers in Region

RH127463

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	134,654,201 - 134,654,408 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	145,146,104 - 145,146,310	NCBI	Rnor6.0
Rnor_5.0	7	142,925,354 - 142,925,560	UniSTS	Rnor5.0
RGSC_v3.4	7	142,428,354 - 142,428,560	UniSTS	RGSC3.4
Celera	7	131,078,280 - 131,078,486	UniSTS
RH 3.4 Map	7	1063.5	UniSTS
Cytogenetic Map	7	q36	UniSTS

BE120220

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	134,648,502 - 134,648,665 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	145,140,408 - 145,140,570	NCBI	Rnor6.0
Rnor_5.0	7	142,919,658 - 142,919,820	UniSTS	Rnor5.0
RGSC_v3.4	7	142,422,658 - 142,422,820	UniSTS	RGSC3.4
Celera	7	131,072,584 - 131,072,746	UniSTS
RH 3.4 Map	7	1063.5	UniSTS
Cytogenetic Map	7	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									74		14
Low	3	43	22	6	19	6	8	11		35	24	10	8
Below cutoff			33	33		33					3	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242386	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF327905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF327906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF327907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M94537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000055272 ⟹ ENSRNOP00000052147

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	134,627,322 - 134,654,580 (+)	Ensembl
Rnor_6.0 Ensembl	7	145,117,951 - 145,145,376 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099138 ⟹ ENSRNOP00000095772

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	134,639,118 - 134,654,580 (+)	Ensembl

RefSeq Acc Id:

NM_022710 ⟹ NP_073201

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	134,627,378 - 134,653,474 (+)	NCBI
Rnor_6.0	7	145,117,951 - 145,145,376 (+)	NCBI
Rnor_5.0	7	142,899,029 - 142,925,733 (+)	NCBI
RGSC_v3.4	7	142,401,489 - 142,427,626 (+)	RGD
Celera	7	131,051,310 - 131,077,552 (+)	RGD

Sequence:

show sequence

AGCCCTGCTAGCTTGGGCCGATCCCAGACACACCGGCCTGGCTAGTCCACGCCAGCCGCAGACG
GTGGCTGAGCATGGAGCTGTCCCCCCGCAGTCCTCCAGAGATGCTGGAGTCGGATTGCCCGTCA
CCCCTGGAGCTGAAGTCAGCCCCCAGCAAGAAGATGTGGATTAAGCTACGGTCTCTGCTGCGCT
ACATGGTGAAGCAGTTGGAGAATGGGGAGGTTAACATCGAGGAGCTGAAGAAAAACCTGGAATA
CACAGCTTCCCTGCTGGAAGCTGTCTACATTGATGAGACAAGGCAAATCTTGGACACTGAAGAT
GAGCTTCGGGAACTTCGGTCAGATGCCGTGCCTTCAGAGGTGCGGGACTGGCTGGCCTCCACCT
TCACCCAGCAGACCCGAGCCAAAGGTCGCAGGGCAGAAGAGAAACCCAAGTTCCGAAGCATTGT
GCACGCTGTGCAGGCTGGGATCTTCGTGGAGCGGATGTTCCGGAGAACGTATACCGCTGTGGGT
CCCACGTATTCTACTGCAGTCCACAACTGTCTCAAGAACCTGGACGTCTGGTGCTTCGATGTCT
TCTCTTTGAACCGGGCAGCTGATGACCACGCTCTGAGGACCATTGTTTTTGAGTTGCTGACTCG
GCATAGCCTCATCAGCCGCTTCAAGATTCCCACAGTGTTTCTGATGAGTTTTCTGGAGGCCTTA
GAGACAGGCTACGGGAAATATAAGAACCCTTACCACAACCAGATCCATGCCGCTGACGTGACCC
AGACTGTCCATTGCTTCCTGCTCCGCACAGGCATGGTGCACTGCCTGTCAGAGATTGAGGTCTT
GGCCATCATCTTCGCGGCAGCCATCCATGACTATGAGCACACAGGCACAACCAACAGCTTCCAC
ATCCAGACCAAGTCAGAATGCGCCATCCTGTACAATGACCGATCGGTGCTGGAGAATCACCACA
TCAGCTCTGTTTTCCGAATGATGCAGGATGATGAGATGAACATTTTTATCAATCTCACCAAGGA
TGAATTCGTAGAGCTGCGGGCCCTGGTCATTGAGATGGTGTTAGCCACAGACATGTCCTGCCAT
TTCCAGCAAGTGAAGACTATGAAGACAGCCCTGCAGCAGCTTGAAAGGATTGACAAATCCAAGG
CCCTGTCTCTTCTGCTTCATGCTGCTGACATCAGCCACCCAACCAAGCAGTGGTCAGTCCACAG
CCGCTGGACCAAGGCCCTAATGGAAGAGTTCTTCCGCCAGGGTGACAAGGAGGCAGAGCTGGGC
TTGCCCTTCTCTCCACTCTGTGACCGCACCTCCACATTGGTGGCCCAGTCCCAGATAGGTTTCA
TTGACTTCATTGTGGAGCCCACCTTCTCTGTGCTGACTGATGTGGCAGAAAAGAGTGTCCAGCC
CTTGACAGATGATGATTCCAAGTCTAAAAGTCAGCCCAGCTTCCAGTGGCGCCAGCCTTCTTTA
GATGTGGACGTAGGAGACCCCAACCCTGATGTGGTCAGTTTCCGCTCCACCTGGACCAAGTACA
TTCAAGAGAATAAACAGAAGTGGAAGGAACGGGCAGCGAGTGGCATCACCAACCAGATGTCCAT
TGATGAACTGTCCCCCTGTGAGGAAGAAGCCCCATCCTCCCCTGCAGAAGATGAGCACAACCAG
AATGGGAATCTGGATTAGGGAACTGGGAGCTGGCCAGGTCCTCACTGAGTCCAAAGTCTTCGAT
GTCATTAGCACTATCCATCAGGACTGGTTCCCCCATCTGCTCCAAGGGAGTGTGTTGGTTGTGA
TAGAGACAGCCCACCTGAGAGCCAAATGTTGGAGCAGGT

hide sequence

RefSeq Acc Id:

XM_006242386 ⟹ XP_006242448

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	134,638,954 - 134,654,581 (+)	NCBI
Rnor_6.0	7	145,129,119 - 145,147,711 (+)	NCBI
Rnor_5.0	7	142,899,029 - 142,925,733 (+)	NCBI

Sequence:

show sequence

GCCAGTCCCCGCCCACCCCCTCCATTCTCTTTGTTCAAACAAATTCCCCCGTGACTTTTCACTC
ACGATGGAGTGGGATGCACTTCTCTTTGTCTGTGAGCCTTCTCTGGCCTCTAACCTCTGCAAGC
CCCTTCCCAAGTGCAAGTAATTTTGTGGGGCCCTCCTGCCTTGAGCATTCTCTCAGGTGCACTA
AGGATCCTGGACGGTTCTAGAAGAAGCCAGAATTTGCAGGAGCTGGATCGCTGCTTAGCCTCTC
TGGTTTCTGGCTGGGTCCCTTCCACTCCTACCATAGACTTCTCTGTGACAAATTCAGGATGGTT
CCCTGTCCCTGCCTCCGGACATTGCTTGCTAATCCCTTTTTCCCAAAGAGGAGCCCCACCTCCT
TAGAGCAAGGGGCTGGCCTGTGCTATTTCTGGCCTTTCTGGGACTCTTCTGACAGATTCTTGTT
TTCAGTCTGATTCAGATGTGAAACTTTTCCCGAGGCCTCTCACCCAGTTCCTGTGGGCTAGGTC
TCTGTCTCATCACCCCTCTAGCCAGGCCCTTTCCGTTTCACAAAGTGCTCTCTGGTCAGTTTCT
CTGTTCTGCTGGGACCTGGAAGAGGAAGTCCCGGGTTCAAGAGGGAGTTGTTCCCCAGTAGGGG
CCCTTGTGCCCTGGGGTCAGTCTTTTGATACTTTGAAGTAGGGAACTTTGATTTCCATGGCAAA
CCCTGTTCCTGTCCAGAGGAGCCACCTCCAGGGCCCCATCCTCAGGCTGCGCTACATGGTGAAG
CAGTTGGAGAATGGGGAGGTTAACATCGAGGAGCTGAAGAAAAACCTGGAATACACAGCTTCCC
TGCTGGAAGCTGTCTACATTGATGAGACAAGGCAAATCTTGGACACTGAAGATGAGCTTCGGGA
ACTTCGGTCAGATGCCGTGCCTTCAGAGGTGCGGGACTGGCTGGCCTCCACCTTCACCCAGCAG
ACCCGAGCCAAAGGTCGCAGGGCAGAAGAGAAACCCAAGTTCCGAAGCATTGTGCACGCTGTGC
AGGCTGGGATCTTCGTGGAGCGGATGTTCCGGAGAACGTATACCGCTGTGGGTCCCACGTATTC
TACTGCAGTCCACAACTGTCTCAAGAACCTGGACGTCTGGTGCTTCGATGTCTTCTCTTTGAAC
CGGGCAGCTGATGACCACGCTCTGAGGACCATTGTTTTTGAGTTGCTGACTCGGCATAGCCTCA
TCAGCCGCTTCAAGATTCCCACAGTGTTTCTGATGAGTTTTCTGGAGGCCTTAGAGACAGGCTA
CGGGAAATATAAGAACCCTTACCACAACCAGATCCATGCCGCTGACGTGACCCAGACTGTCCAT
TGCTTCCTGCTCCGCACAGGCATGGTGCACTGCCTGTCAGAGATTGAGGTCTTGGCCATCATCT
TCGCGGCAGCCATCCATGACTATGAGCACACAGGCACAACCAACAGCTTCCACATCCAGACCAA
GTCAGAATGCGCCATCCTGTACAATGACCGATCGGTGCTGGAGAATCACCACATCAGCTCTGTT
TTCCGAATGATGCAGGATGATGAGATGAACATTTTTATCAATCTCACCAAGGATGAATTCGTAG
AGCTGCGGGCCCTGGTCATTGAGATGGTGTTAGCCACAGACATGTCCTGCCATTTCCAGCAAGT
GAAGACTATGAAGACAGCCCTGCAGCAGCTTGAAAGGATTGACAAATCCAAGGCCCTGTCTCTT
CTGCTTCATGCTGCTGACATCAGCCACCCAACCAAGCAGTGGTCAGTCCACAGCCGCTGGACCA
AGGCCCTAATGGAAGAGTTCTTCCGCCAGGGTGACAAGGAGGCAGAGCTGGGCTTGCCCTTCTC
TCCACTCTGTGACCGCACCTCCACATTGGTGGCCCAGTCCCAGATAGGTTTCATTGACTTCATT
GTGGAGCCCACCTTCTCTGTGCTGACTGATGTGGCAGAAAAGAGTGTCCAGCCCTTGACAGATG
ATGATTCCAAGTCTAAAAGTCAGCCCAGCTTCCAGTGGCGCCAGCCTTCTTTAGATGTGGACGT
AGGAGACCCCAACCCTGATGTGGTCAGTTTCCGCTCCACCTGGACCAAGTACATTCAAGAGAAT
AAACAGAAGTGGAAGGAACGGGCAGCGAGTGGCATCACCAACCAGATGTCCATTGATGAACTGT
CCCCCTGTGAGGAAGAAGCCCCATCCTCCCCTGCAGAAGATGAGCACAACCAGAATGGGAATCT
GGATTAGGGAACTGGGAGCTGGCCAGGTCCTCACTGAGTCCAAAGTCTTCGATGTCATTAGCAC
TATCCATCAGGACTGGTTCCCCCATCTGCTCCAAGGGAGTGTGTTGGTTGTGATAGAGACAGCC
CACCTGAGAGCCAAATGTTGGAGCAGGTGGGGTGTGGGAAGGGCCCCTCTCCACCCACAGGCCC
CCAGTGGTCATTGTGCCCATCCCTTGCCTCTGGACTCCCTCCTTGGCCAGGTGGCCACTTGGGA
GGAGTAAACCCCCTGCAGGCTTCCTACAGTCTGGAGGGGAGGGTCAGAGACGCCAGCCCCCTGG
GCCCTCCCCATCCTTCTTGCCTCCAAGTTTCTAAGCAATACATTTTGGGGGTTCCCTCAGTCCC
CCACCCCAGATCTTAGCTGGCAGGTCTGGGTTTTCTTTCTCTTCCCCAAGAAAGGGCCAGAAAT
AGGATAGGAAGCTGGCAGTTTTCAAAGCCCTGCATGGGAGGGCAGGTGTCCCTTCAGGTTCCTT
CCTAGGATGGTGTGGGGGACGTCCTCTTGACCCCATACCTGCACTTCTTCAGTCCAGTCCCTTG
CAAAGTCTCTTTCTCCTGTGCCCAGACAGTGGCTGGGAGAGGAGAGGAGCCATTGGGATTCTGT
CTGAGGGAAATCTTTCCCGGAGTCCTCAAGAACTTGGGGATGGTCTGGGCTTGGTGGGCTTGTA
ACAAAAAGGGTTTTGGCCCTTTGCTTCCTTCCTGTCCCCGGGAACTCATCCGACCAATGTCTGT
AAATGCTCCGAGGTCTTCCTTCAGGATGTATCTTATGAGCAAAGGAAGGAGAGAGCAGCTAGCC
CCAGTGCAATCAGGGTAAAGTATTACCCAGTAATCCATGTTGTCACAGAGCAGGTCCTTCCTGA
CTCCCTTCTCCCAGAACTGGCCCACTAAGAGAGTCCCCTCCCCTGGGCCCCCGGTGGGTGGAAG
GCAGATGGGGAGGGGCTCAGGGCTGTTGCAACTTGGAGCACCCAGAGCAGAGTGCAGCCAGGTA
AAGCCTCTTCCTGTCCTCAGGCTCCTTGTCCCACCTCACCCCATATAAGGCCAAGTCCAGGTGA
CTGCCTTCTCCTCTCTTGTAAATACATGCATTTGTACAGTGGGCCCTGTTCTTGTGAAGTCCAT
CTCCATGGTCATTAGACCTGACACTCCAAATCGCATGTGACTCCCCCATGCTCTTGGTCTCCCA
GGCCCCTGCTATAGCCAGAGATCAATAAAGAAGGGAGACTGGCTGGATGTGTGTGGTGTTCATT
AGGTAGAAGCTCTCTCACGTGTCATTTATAGTTATCTTCCTAAGCTAGACAGAACTCTGCCATG
GTATTCTCCATGAGTGTTGAAGCGGGGATTCAAGTAAAGCCTATCTGGGGGTGGGGGTGGGGCG
CTACGGCACACAGTCCTTCACTGCCCAGGCTATGCTCTTCTTAGCTATGTGGTACTGCTGAAGA
AAAGGGGACGAAAGAGTCTTCCTTCTCCCTCCATCTCTTTAATTCTTTGGGAAAATCAGAATCA
GCAGCAGAAGCCTGGCTAGAATCAGAGACCACTTCTCCATTTGTGCATGGTGTTAGTCTTGCCC
TGACCTTAGTAGGTAGGACAATGGAAGAGGGGTTTCTAGTCACTGGGTTTTCTGACAGTCTTTG
TTGTCAGGTTAGAATAAGGAACAGTGCCACACAATTGGAACCAGATTCCAAATACTCCCTTTGT
CAGGGGTTTCGGGACAAGATGCACTTCCCATTTATGTCCAGCAGATGGTGCTATAGCAAGCCCT
CGCTGGTCTGGGTATCTGCTTTAGAGTGGCAGTCTCCCAAGTAGGCGGCCCTGCTACGTGGGCG
GAGCTTTCCACAGTAAGAAAGGAAAGCCTTGAAGTGATCTCCTACTTCCACACTCCTCTTTTTC
TTTATGCTAGTAGAGGCTAGGCTTCAGTCAGTTTCCTATTTCCTAGCTTAGTTGGTCCTGAGGG
TGGGGGCTGTGGGGTGCAGACAAGAGCCGAGGGAGGAAGGAATCCCCAGGCTGGAAAGAAGAAA
AGCACCAAGGACCTAACACCAAATTTATCACGTTTAAAAACAAGAGATTAAGAAACATCCAGTG
TCCATGAACTTCCACACTCACTGGCGATCCCCGGATGTCAACTTCTGTCAGACCTGTTTCGGGG
GAGGAAAGGGGAGGTGACTGAAGGGTCATAGGCTCATCCTTCTGGTCAGCCCAGCCTCTGGGGG
AGTCCTGCTATGGATCTCAGTCTAAGCCCCTTCTCTTCTAAGCCCACAGTACTTTGGTTCCAAC
TGCCGTTTATTAAAAAATAAAATTAGTTCTATGTTCTATTTCCATCACCTGTTCCAGAAGGTCT
ACACAACAAAGTCTCCATTGGATCCTTCCTGCAGTCACTTAATCCCTCCTCTCTGTCAGAGGGC
GTCTCTTAGCACAAAGGCTAACTTATTAGTGACCAAATAAAGCTGCTCCTTTGTCTGTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_073201	(Get FASTA)	NCBI Sequence Viewer
	XP_006242448	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA16530	(Get FASTA)	NCBI Sequence Viewer
	AAK15739	(Get FASTA)	NCBI Sequence Viewer
	AAK15740	(Get FASTA)	NCBI Sequence Viewer
	AAK15741	(Get FASTA)	NCBI Sequence Viewer
	EDL86779	(Get FASTA)	NCBI Sequence Viewer
	EDL86780	(Get FASTA)	NCBI Sequence Viewer
	Q01066	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_073201 ⟸ NM_022710

- UniProtKB:

Q548L3 (UniProtKB/Swiss-Prot), Q01066 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLEYTAS
LLEAVYIDETRQILDTEDELRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPKFRSIVHAV
QAGIFVERMFRRTYTAVGPTYSTAVHNCLKNLDVWCFDVFSLNRAADDHALRTIVFELLTRHSL
ISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIEVLAII
FAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQDDEMNIFINLTKDEFV
ELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKSKALSLLLHAADISHPTKQWSVHSRWT
KALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLTD
DDSKSKSQPSFQWRQPSLDVDVGDPNPDVVSFRSTWTKYIQENKQKWKERAASGITNQMSIDEL
SPCEEEAPSSPAEDEHNQNGNLD

hide sequence

RefSeq Acc Id:	XP_006242448 ⟸ XM_006242386
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ANV0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MANPVPVQRSHLQGPILRLRYMVKQLENGEVNIEELKKNLEYTASLLEAVYIDETRQILDTEDE LRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTAVGP TYSTAVHNCLKNLDVWCFDVFSLNRAADDHALRTIVFELLTRHSLISRFKIPTVFLMSFLEALE TGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHI QTKSECAILYNDRSVLENHHISSVFRMMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHF QQVKTMKTALQQLERIDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGL PFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLTDDDSKSKSQPSFQWRQPSLD VDVGDPNPDVVSFRSTWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPSSPAEDEHNQN GNLD hide sequence

RefSeq Acc Id:

ENSRNOP00000052147 ⟸ ENSRNOT00000055272

RefSeq Acc Id:

ENSRNOP00000095772 ⟸ ENSRNOT00000099138

Protein Domains

3'5'-cyclic nucleotide phosphodiesterase N-terminal PDEase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q01066-F1-model_v2	AlphaFold	Q01066	1-535	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695719

Promoter ID:

EPDNEW_R6244

Type:

multiple initiation site

Name:

Pde1b_1

Description:

phosphodiesterase 1B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	145,117,856 - 145,117,916	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3278	AgrOrtholog
BioCyc Gene	G2FUF-31868	BioCyc
Ensembl Genes	ENSRNOG00000036828	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000052147	ENTREZGENE
	ENSRNOP00000052147.1	UniProtKB/Swiss-Prot
	ENSRNOP00000095772	ENTREZGENE
	ENSRNOP00000095772.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000055272	ENTREZGENE
	ENSRNOT00000055272.4	UniProtKB/Swiss-Prot
	ENSRNOT00000099138	ENTREZGENE
	ENSRNOT00000099138.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1300.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	HD/PDEase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PDEase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PDEase_catalytic_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PDEase_catalytic_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PDEase_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PDEase_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29691	UniProtKB/Swiss-Prot
NCBI Gene	29691	ENTREZGENE
PANTHER	CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	PDEase_I	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PDEase_I_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pde1b	PhenoGen
PRINTS	PDIESTERASE1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	PDEASE_I_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PDEASE_I_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	HDc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	HD-domain/PDEase-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6ANV0	ENTREZGENE, UniProtKB/TrEMBL
	PDE1B_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q548L3	ENTREZGENE
	Q99MN4_RAT	UniProtKB/TrEMBL
	Q99MN5_RAT	UniProtKB/TrEMBL
UniProt Secondary	Q548L3	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-30	Pde1b	phosphodiesterase 1B	Pde1b	phosphodiesterase 1B, calmodulin-dependent	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-08-29	Pde1b	phosphodiesterase 1B, calmodulin-dependent	Pde1b	phosphodiesterase 1B, Ca2+calmodulin dependent	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Pde1b	phosphodiesterase 1B, Ca2+calmodulin dependent		phosphodiesterase 1B	Name updated	1299863	APPROVED
2002-06-10	Pde1b	phosphodiesterase 1B			Name updated	70584	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)