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Gene: Mchr1 (melanin-concentrating hormone receptor 1) Rattus norvegicus
Symbol: Mchr1
Name: melanin-concentrating hormone receptor 1
RGD ID: 619841
Description: Exhibits hormone binding activity; melanin-concentrating hormone receptor activity; and protein C-terminus binding activity. Involved in cell surface receptor signaling pathway; positive regulation of calcium ion transport; and positive regulation of cytosolic calcium ion concentration. Localizes to plasma membrane. Biomarker of obesity. Human ortholog(s) of this gene implicated in morbid obesity. Orthologous to human MCHR1 (melanin concentrating hormone receptor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
Also known as: G protein-coupled receptor 24; G-protein coupled receptor 24; Gpr24; MCH receptor 1; Mch-1r; MCH-R1; MCH1R; MCHR; MCHR-1; SLC-1; Slc1; somatostatin receptor-like protein
Homo sapiens (human) : MCHR1 (melanin concentrating hormone receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Mchr1 (melanin-concentrating hormone receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mchr1 (melanin concentrating hormone receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MCHR1 (melanin concentrating hormone receptor 1)
Canis lupus familiaris (dog) : MCHR1 (melanin concentrating hormone receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mchr1 (melanin concentrating hormone receptor 1)
Sus scrofa (pig) : MCHR1 (melanin concentrating hormone receptor 1)
Chlorocebus sabaeus (African green monkey) : MCHR1 (melanin concentrating hormone receptor 1)
Heterocephalus glaber (naked mole-rat) : Mchr1 (melanin concentrating hormone receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07122,456,846 - 122,459,324 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,456,799 - 122,459,960 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,432,538 - 122,435,016 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,557,141 - 119,559,619 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17119,591,370 - 119,593,849 (+)NCBI
Celera7109,080,262 - 109,082,740 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mchr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619841
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.