Mchr1 (melanin-concentrating hormone receptor 1) - Rat Genome Database

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Gene: Mchr1 (melanin-concentrating hormone receptor 1) Rattus norvegicus
Analyze
Symbol: Mchr1
Name: melanin-concentrating hormone receptor 1
RGD ID: 619841
Description: Enables hormone binding activity and melanin-concentrating hormone receptor activity. Involved in cell surface receptor signaling pathway; positive regulation of calcium ion transport; and positive regulation of cytosolic calcium ion concentration. Predicted to be located in ciliary membrane and non-motile cilium. Predicted to be active in neuron projection and plasma membrane. Biomarker of obesity. Human ortholog(s) of this gene implicated in morbid obesity. Orthologous to human MCHR1 (melanin concentrating hormone receptor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: G protein-coupled receptor 24; G-protein coupled receptor 24; Gpr24; MCH receptor 1; Mch-1r; MCH-R1; MCH1R; MCHR; MCHR-1; SLC-1; Slc1; somatostatin receptor-like protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,641,721 - 114,644,913 (+)NCBIGRCr8
mRatBN7.27112,761,554 - 112,764,746 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,761,554 - 112,764,032 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7114,524,098 - 114,526,580 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,747,649 - 116,750,131 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,717,002 - 116,719,482 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,456,846 - 122,459,324 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,456,799 - 122,459,960 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,432,538 - 122,435,016 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,557,141 - 119,559,619 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17119,591,370 - 119,593,849 (+)NCBI
Celera7109,080,262 - 109,082,740 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MIZIP, a highly conserved, vertebrate specific melanin-concentrating hormone receptor 1 interacting zinc-finger protein. Bachner D, etal., FEBS Lett 2002 Aug 28;526(1-3):124-8.
2. Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity. Bell CG, etal., Diabetes. 2005 Oct;54(10):3049-55.
3. Increases in melanin-concentrating hormone and MCH receptor levels in the hypothalamus of dietary-obese rats. Elliott JC, etal., Brain Res Mol Brain Res. 2004 Sep 28;128(2):150-9.
4. Interaction of neurochondrin with the melanin-concentrating hormone receptor 1 interferes with G protein-coupled signal transduction but not agonist-mediated internalization. Francke F, etal., J Biol Chem. 2006 Oct 27;281(43):32496-507. Epub 2006 Aug 31.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Cloning of the rat brain cDNA encoding for the SLC-1 G protein-coupled receptor reveals the presence of an intron in the gene. Lakaye B, etal., Biochim Biophys Acta 1998 Feb 4;1401(2):216-20.
8. The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor. Lembo PM, etal., Nat Cell Biol. 1999 Sep;1(5):267-71.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
12. GOA pipeline RGD automated data pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Functional role of N-linked glycosylation on the rat melanin-concentrating hormone receptor 1. Saito Y, etal., FEBS Lett 2003 Jan 2;533(1-3):29-34.
15. The basic residues in the membrane-proximal C-terminal tail of the rat melanin-concentrating hormone receptor 1 are required for receptor function. Tetsuka M, etal., Endocrinology. 2004 Aug;145(8):3712-23. Epub 2004 Apr 29.
Additional References at PubMed
PMID:8977118   PMID:10421368   PMID:12620396   PMID:15476926   PMID:15590649   PMID:15845622   PMID:15950311   PMID:16359819   PMID:18062961   PMID:18334641   PMID:18760349   PMID:18849359  
PMID:19428776   PMID:21925200   PMID:21946196   PMID:22139371   PMID:22209364   PMID:23029470   PMID:23351594   PMID:25617691   PMID:26456505   PMID:27579857   PMID:28154160   PMID:32530066  
PMID:33197527   PMID:36565982  


Genomics

Comparative Map Data
Mchr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,641,721 - 114,644,913 (+)NCBIGRCr8
mRatBN7.27112,761,554 - 112,764,746 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,761,554 - 112,764,032 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7114,524,098 - 114,526,580 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,747,649 - 116,750,131 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,717,002 - 116,719,482 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,456,846 - 122,459,324 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,456,799 - 122,459,960 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,432,538 - 122,435,016 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,557,141 - 119,559,619 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17119,591,370 - 119,593,849 (+)NCBI
Celera7109,080,262 - 109,082,740 (+)NCBICelera
Cytogenetic Map7q34NCBI
MCHR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,679,484 - 40,682,812 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,679,273 - 40,682,812 (+)EnsemblGRCh38hg38GRCh38
GRCh372241,075,488 - 41,078,816 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,405,128 - 39,408,764 (+)NCBINCBI36Build 36hg18NCBI36
Build 342239,399,736 - 39,403,318NCBI
Celera2224,878,864 - 24,882,500 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2224,037,016 - 24,040,650 (+)NCBIHuRef
CHM1_12241,035,201 - 41,038,835 (+)NCBICHM1_1
T2T-CHM13v2.02241,151,449 - 41,154,777 (+)NCBIT2T-CHM13v2.0
Mchr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,119,700 - 81,123,165 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,119,700 - 81,123,165 (+)EnsemblGRCm39 Ensembl
GRCm381581,235,499 - 81,238,964 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,235,499 - 81,238,964 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,065,929 - 81,069,394 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,063,029 - 81,065,367 (+)NCBIMGSCv36mm8
Celera1583,352,799 - 83,356,252 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.02NCBI
Mchr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,343,759 - 26,347,520 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,343,771 - 26,347,374 (+)NCBIChiLan1.0ChiLan1.0
MCHR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22350,512,835 - 50,516,718 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12253,212,725 - 53,216,607 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02221,577,190 - 21,581,062 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12239,673,698 - 39,677,517 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2239,673,698 - 39,677,517 (+)Ensemblpanpan1.1panPan2
MCHR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,526,687 - 24,560,948 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1024,526,693 - 24,559,836 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1024,462,281 - 24,464,655 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01025,276,788 - 25,311,181 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1025,276,794 - 25,280,056 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,990,613 - 24,992,985 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01025,312,293 - 25,314,664 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01025,486,758 - 25,489,135 (-)NCBIUU_Cfam_GSD_1.0
Mchr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049458,143,469 - 8,147,147 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364921,153,651 - 1,157,142 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364921,153,895 - 1,156,980 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCHR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,735,825 - 7,738,701 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,735,752 - 7,752,006 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,916,103 - 4,918,861 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCHR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11923,240,509 - 23,245,553 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1923,241,487 - 23,243,950 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045102,341,335 - 102,346,097 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mchr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,801,948 - 7,805,635 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247527,801,867 - 7,805,791 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mchr1
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:65
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000025564
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 15
Low 1 3 6 49 4 32 1 3
Below cutoff 2 17 33 22 6 22 5 5 10 27 7 8 5

Sequence


RefSeq Acc Id: ENSRNOT00000025564   ⟹   ENSRNOP00000025564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7112,761,554 - 112,764,032 (+)Ensembl
Rnor_6.0 Ensembl7122,456,799 - 122,459,960 (+)Ensembl
RefSeq Acc Id: NM_031758   ⟹   NP_113946
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,641,721 - 114,644,199 (+)NCBI
mRatBN7.27112,761,554 - 112,764,032 (+)NCBI
Rnor_6.07122,456,846 - 122,459,324 (+)NCBI
Rnor_5.07122,432,538 - 122,435,016 (+)NCBI
RGSC_v3.47119,557,141 - 119,559,619 (+)RGD
Celera7109,080,262 - 109,082,740 (+)RGD
Sequence:
RefSeq Acc Id: XM_039079955   ⟹   XP_038935883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,641,829 - 114,644,913 (+)NCBI
mRatBN7.27112,761,712 - 112,764,746 (+)NCBI
RefSeq Acc Id: NP_113946   ⟸   NM_031758
- UniProtKB: A0A140TAD3 (UniProtKB/Swiss-Prot),   P97639 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025564   ⟸   ENSRNOT00000025564
RefSeq Acc Id: XP_038935883   ⟸   XM_039079955
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97639-F1-model_v2 AlphaFold P97639 1-353 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619841 AgrOrtholog
BioCyc Gene G2FUF-32685 BioCyc
Ensembl Genes ENSRNOG00000018895 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055032055 UniProtKB/Swiss-Prot
  ENSRNOG00060028081 UniProtKB/Swiss-Prot
  ENSRNOG00065029882 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025564 ENTREZGENE
  ENSRNOT00000025564.7 UniProtKB/Swiss-Prot
  ENSRNOT00055055434 UniProtKB/Swiss-Prot
  ENSRNOT00060048761 UniProtKB/Swiss-Prot
  ENSRNOT00065051613 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  MCH1_rcpt UniProtKB/Swiss-Prot
  MCH_rcpt UniProtKB/Swiss-Prot
KEGG Report rno:83567 UniProtKB/Swiss-Prot
NCBI Gene 83567 ENTREZGENE
PANTHER NEUROPEPTIDES RECEPTOR UniProtKB/Swiss-Prot
  PTHR24229:SF91 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Mchr1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  MCH1RECEPTOR UniProtKB/Swiss-Prot
  MCHRECEPTOR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018895 RatGTEx
  ENSRNOG00055032055 RatGTEx
  ENSRNOG00060028081 RatGTEx
  ENSRNOG00065029882 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0A140TAD3 ENTREZGENE
  MCHR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0A140TAD3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Mchr1  melanin-concentrating hormone receptor 1  Gpr24  G protein-coupled receptor 24  Symbol and Name updated 1299863 APPROVED
2004-12-14 Gpr24  G protein-coupled receptor 24    somatostatin receptor-like protein  Name updated 1299863 APPROVED
2002-08-07 Gpr24  somatostatin receptor-like protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_pathway involves in the Ca2+, cAMP and MAP kinases signaling pathways 628540
gene_protein all three N-linked glycosylation sites are glycosylated in vivo 628540
gene_regulation N-glycosylation at Asn23 is important for cell surface expression, ligand binding and signal transduction 628540