Tef (TEF transcription factor, PAR bZIP family member) - Rat Genome Database

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Gene: Tef (TEF transcription factor, PAR bZIP family member) Rattus norvegicus
Analyze
Symbol: Tef
Name: TEF transcription factor, PAR bZIP family member
RGD ID: 3841
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human TEF (TEF transcription factor, PAR bZIP family member); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100910463; TEF, PAR bZIP transcription factor; thyrotroph embryonic factor; thyrotrophic embryonic factor; uncharacterized LOC100910463
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,197,180 - 115,221,930 (+)NCBIGRCr8
mRatBN7.27113,317,191 - 113,341,783 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,317,283 - 113,341,783 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,089,146 - 115,104,243 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,312,643 - 117,327,740 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,282,081 - 117,297,178 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,033,971 - 123,058,606 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,043,503 - 123,058,604 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,005,635 - 123,034,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,164,881 - 120,179,984 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17120,199,287 - 120,211,043 (+)NCBI
Celera7109,645,394 - 109,660,497 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
butanal  (ISO)
C60 fullerene  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlordecone  (ISO)
chloroprene  (EXP,ISO)
choline  (ISO)
chrysene  (ISO)
clobetasol  (ISO)
clothianidin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
Erionite  (ISO)
ethanol  (ISO)
fipronil  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
graphene oxide  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lead diacetate  (EXP)
levofloxacin  (EXP)
methamphetamine  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
styrene  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
tremolite asbestos  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP,ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins. Drolet DW, etal., Genes Dev 1991 Oct;5(10):1739-53.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:24147051  


Genomics

Comparative Map Data
Tef
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,197,180 - 115,221,930 (+)NCBIGRCr8
mRatBN7.27113,317,191 - 113,341,783 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,317,283 - 113,341,783 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,089,146 - 115,104,243 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,312,643 - 117,327,740 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,282,081 - 117,297,178 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,033,971 - 123,058,606 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,043,503 - 123,058,604 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,005,635 - 123,034,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,164,881 - 120,179,984 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17120,199,287 - 120,211,043 (+)NCBI
Celera7109,645,394 - 109,660,497 (+)NCBICelera
Cytogenetic Map7q34NCBI
TEF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,367,455 - 41,399,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,367,333 - 41,399,326 (+)EnsemblGRCh38hg38GRCh38
GRCh372241,763,459 - 41,795,330 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,107,909 - 40,125,276 (+)NCBINCBI36Build 36hg18NCBI36
Build 342240,102,462 - 40,119,828NCBI
Celera2225,569,791 - 25,601,729 (+)NCBICelera
Cytogenetic Map22q13.2ENTREZGENE
HuRef2224,729,737 - 24,761,736 (+)NCBIHuRef
CHM1_12241,723,259 - 41,755,245 (+)NCBICHM1_1
T2T-CHM13v2.02241,846,283 - 41,878,148 (+)NCBIT2T-CHM13v2.0
Tef
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,686,874 - 81,711,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,686,622 - 81,711,064 (+)EnsemblGRCm39 Ensembl
GRCm381581,802,673 - 81,826,863 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,802,421 - 81,826,863 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,633,103 - 81,657,293 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,630,072 - 81,654,118 (+)NCBIMGSCv36mm8
Celera1583,921,481 - 83,945,730 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.25NCBI
Tef
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,956,285 - 26,979,045 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,956,285 - 26,978,734 (+)NCBIChiLan1.0ChiLan1.0
TEF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22351,199,380 - 51,231,981 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12253,899,206 - 53,931,265 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02222,263,607 - 22,295,750 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12240,350,470 - 40,382,724 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,348,770 - 40,382,724 (+)Ensemblpanpan1.1panPan2
TEF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,852,551 - 23,878,353 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,838,788 - 23,878,190 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,785,052 - 23,810,494 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,597,068 - 24,622,524 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,579,743 - 24,622,510 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,313,806 - 24,339,243 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,634,699 - 24,660,129 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,809,157 - 24,834,606 (-)NCBIUU_Cfam_GSD_1.0
Tef
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,495,566 - 7,517,734 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936492505,906 - 528,384 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936492505,978 - 528,087 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,119,359 - 7,144,498 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,119,354 - 7,135,171 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TEF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11923,910,015 - 23,939,935 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1923,910,119 - 23,940,043 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045101,479,795 - 101,510,399 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tef
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,159,362 - 7,186,022 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247527,159,791 - 7,186,043 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tef
25 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:424
Count of miRNA genes:230
Interacting mature miRNAs:301
Transcripts:ENSRNOT00000026258
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
RH66783  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27113,338,421 - 113,338,597 (+)MAPPERmRatBN7.2
Rnor_6.07123,055,245 - 123,055,420NCBIRnor6.0
Rnor_5.07123,031,024 - 123,031,199UniSTSRnor5.0
RGSC_v3.47120,176,623 - 120,176,798UniSTSRGSC3.4
Celera7109,657,136 - 109,657,311UniSTS
Cytogenetic Map7q34UniSTS
RH130255  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27113,341,519 - 113,341,737 (+)MAPPERmRatBN7.2
Rnor_6.07123,058,343 - 123,058,560NCBIRnor6.0
Rnor_5.07123,034,122 - 123,034,339UniSTSRnor5.0
RGSC_v3.47120,179,721 - 120,179,938UniSTSRGSC3.4
Celera7109,660,234 - 109,660,451UniSTS
RH 3.4 Map7887.2UniSTS
Cytogenetic Map7q34UniSTS
RH141466  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27113,331,540 - 113,331,725 (+)MAPPERmRatBN7.2
Rnor_6.07123,048,333 - 123,048,517NCBIRnor6.0
Rnor_5.07123,024,112 - 123,024,296UniSTSRnor5.0
RGSC_v3.47120,169,711 - 120,169,895UniSTSRGSC3.4
Celera7109,650,224 - 109,650,408UniSTS
RH 3.4 Map5902.0UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000026258   ⟹   ENSRNOP00000026258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,326,711 - 113,341,779 (+)Ensembl
Rnor_6.0 Ensembl7123,043,503 - 123,058,604 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086355   ⟹   ENSRNOP00000072259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7123,043,584 - 123,055,783 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107707   ⟹   ENSRNOP00000081617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,317,283 - 113,341,783 (+)Ensembl
RefSeq Acc Id: NM_019194   ⟹   NP_062067
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,206,827 - 115,221,930 (+)NCBI
mRatBN7.27113,326,711 - 113,341,783 (+)NCBI
Rnor_6.07123,043,503 - 123,058,606 (+)NCBI
Rnor_5.07123,005,635 - 123,034,385 (+)NCBI
RGSC_v3.47120,164,881 - 120,179,984 (+)RGD
Celera7109,645,394 - 109,660,497 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242068   ⟹   XP_006242130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,197,180 - 115,221,930 (+)NCBI
mRatBN7.27113,317,191 - 113,341,783 (+)NCBI
Rnor_6.07123,033,971 - 123,058,606 (+)NCBI
Rnor_5.07123,005,635 - 123,034,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594699   ⟹   XP_017450188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,197,659 - 115,221,930 (+)NCBI
mRatBN7.27113,317,550 - 113,341,783 (+)NCBI
Rnor_6.07123,034,275 - 123,058,606 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078573   ⟹   XP_038934501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,206,411 - 115,214,129 (+)NCBI
mRatBN7.27113,326,666 - 113,331,892 (+)NCBI
RefSeq Acc Id: XM_063263117   ⟹   XP_063119187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,197,871 - 115,221,930 (+)NCBI
RefSeq Acc Id: NP_062067   ⟸   NM_019194
- UniProtKB: Q3T1I8 (UniProtKB/Swiss-Prot),   P41224 (UniProtKB/Swiss-Prot),   A6HT20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242130   ⟸   XM_006242068
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZT24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450188   ⟸   XM_017594699
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000026258   ⟸   ENSRNOT00000026258
Ensembl Acc Id: ENSRNOP00000072259   ⟸   ENSRNOT00000086355
RefSeq Acc Id: XP_038934501   ⟸   XM_039078573
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000081617   ⟸   ENSRNOT00000107707
RefSeq Acc Id: XP_063119187   ⟸   XM_063263117
- Peptide Label: isoform X3
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P41224-F1-model_v2 AlphaFold P41224 1-301 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695517
Promoter ID:EPDNEW_R6041
Type:multiple initiation site
Name:Tef_1
Description:TEF, PAR bZIP transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07123,043,491 - 123,043,551EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3841 AgrOrtholog
BioCyc Gene G2FUF-32662 BioCyc
Ensembl Genes ENSRNOG00000019383 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055028339 UniProtKB/Swiss-Prot
  ENSRNOG00060030458 UniProtKB/Swiss-Prot
  ENSRNOG00065028597 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026258.7 UniProtKB/Swiss-Prot
  ENSRNOT00000107707.1 UniProtKB/TrEMBL
  ENSRNOT00055049056 UniProtKB/Swiss-Prot
  ENSRNOT00060052882 UniProtKB/Swiss-Prot
  ENSRNOT00065049295 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7932583 IMAGE-MGC_LOAD
InterPro bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAR_bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29362 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:124618 IMAGE-MGC_LOAD
NCBI Gene 29362 ENTREZGENE
PANTHER PTHR11988 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11988:SF24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam bZIP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tef PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019383 RatGTEx
  ENSRNOG00055028339 RatGTEx
  ENSRNOG00060030458 RatGTEx
  ENSRNOG00065028597 RatGTEx
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57959 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZT24 ENTREZGENE, UniProtKB/TrEMBL
  A6HT19_RAT UniProtKB/TrEMBL
  A6HT20 ENTREZGENE, UniProtKB/TrEMBL
  P41224 ENTREZGENE
  Q3T1I8 ENTREZGENE
  TEF_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q3T1I8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 Tef  TEF transcription factor, PAR bZIP family member  Tef  TEF, PAR bZIP transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-05 Tef  TEF, PAR bZIP transcription factor  Tef  thyrotrophic embryonic factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Tef  thyrotrophic embryonic factor  LOC100910463  uncharacterized LOC100910463  Data merged from RGD:6498257 737654 PROVISIONAL
2012-07-05 LOC100910463  uncharacterized LOC100910463      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-10-23 Tef  thyrotrophic embryonic factor  Tef  thyrotroph embryonic factor   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Tef  thyrotroph embryonic factor       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains DNA-binding and dimerization domains 70036
gene_expression mRNA expressed specifically in the anterior pituitary gland 70036
gene_physical_interaction binds thyroid-stimulating hormone beta (Tshb), albumin D box-binding protein (Dbp), able to homodimerize 70036
gene_product member of the proline and acidic amino acid-rich (PAR) subfamily of basic region/leucine zipper (bZIP) transcription factors 70036