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Gene: Myh9 (myosin, heavy chain 9) Rattus norvegicus
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Symbol: Myh9
Name: myosin, heavy chain 9
Description: Exhibits several functions, including G-protein alpha-subunit binding activity; follicle-stimulating hormone receptor binding activity; and scaffold protein binding activity. Predicted to contribute to actin filament binding activity and actin-dependent ATPase activity. Involved in several processes, including actin cytoskeleton organization; positive regulation of cell communication; and regulation of vesicle-mediated transport. Localizes to several cellular components, including the actin filament; brush border; and lateral plasma membrane. Colocalizes with the endosome and phagocytic vesicle. Biomarker of metabolic acidosis. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autosomal dominant Alport syndrome; blood platelet disease (multiple); end stage renal failure; and proteinuria. Orthologous to human MYH9 (myosin heavy chain 9); PARTICIPATES IN follicle-stimulating hormone signaling pathway; myocarditis pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cellular myosin heavy chain, type A; Myh9l1; myosin heavy chain 9; myosin heavy chain, non-muscle IIa; Myosin heavy polypeptide 9 non-muscle; myosin, heavy chain 9, non-muscle; myosin, heavy chain 9, non-muscle-like 1; myosin, heavy polypeptide 9; Myosin, heavy polypeptide 9, non-muscle; myosin-9; NMIIA; NMMHC II-a; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain A; non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain-A; nonmuscle myosin IIA
Orthologs:
Homo sapiens (human) : MYH9 (myosin heavy chain 9)  HGNC  Alliance
Mus musculus (house mouse) : Myh9 (myosin, heavy polypeptide 9, non-muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh9 (myosin heavy chain 9)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH9 (myosin heavy chain 9)
Canis lupus familiaris (dog) : MYH9 (myosin heavy chain 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh9 (myosin heavy chain 9)
Sus scrofa (pig) : MYH9 (myosin heavy chain 9)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: Gene ID:100911597 and GeneID:25745 on Rnor_6.0 are nearly identical to each other, and are both annotated on chromosome 7. This duplication is likely the result of a genome assembly error, and GeneID:100911597 is thought to better represent the Myh9 locus. [06 Apr 2015]; Note: Gene ID:100911597 and GeneID:25745 on Rnor_6.0 are nearly identical to each other, and are both annotated on chromosome 7. This duplication is likely the result of a genome assembly error, and GeneID:100911597 is thought to better represent the Myh9 locus. [08 Apr 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07118,740,005 - 118,792,507 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,741,110 - 118,792,625 (-)Ensembl
Rnor_5.07118,737,555 - 118,797,086 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47115,681,459 - 115,732,774 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17115,715,686 - 115,767,004 (-)NCBI
Celera7105,684,430 - 105,736,878 (-)NCBICelera
Cytogenetic Map7q34NCBI
RH 3.4 Map7811.2RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Myh9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3140
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.