Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ago2 (argonaute RISC catalytic component 2) Rattus norvegicus
Analyze
Symbol: Ago2
Name: argonaute RISC catalytic component 2
Description: Predicted to have several functions, including RNA binding activity; nuclease activity; and protein C-terminus binding activity. Involved in negative regulation of amyloid precursor protein biosynthetic process. Localizes to the mitochondrion. Orthologous to human AGO2 (argonaute RISC catalytic component 2); PARTICIPATES IN microRNA pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: argonaute 2, RISC catalytic component; argonaute2; eIF-2C 2; eIF2C 2; Eif2c2; eukaryotic translation initiation factor 2C 2; eukaryotic translation initiation factor 2C, 2; Gerp95; golgi ER protein 95 kDa; protein argonaute-2; protein slicer
Orthologs:
Homo sapiens (human) : AGO2 (argonaute RISC catalytic component 2)  HGNC  Alliance
Mus musculus (house mouse) : Ago2 (argonaute RISC catalytic subunit 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago2 (argonaute RISC catalytic component 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO2 (argonaute RISC catalytic component 2)
Canis lupus familiaris (dog) : AGO2 (argonaute RISC catalytic component 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ago2 (argonaute RISC catalytic component 2)
Sus scrofa (pig) : AGO2 (argonaute RISC catalytic component 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07114,339,607 - 114,377,277 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07114,274,582 - 114,312,135 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47110,827,857 - 110,865,589 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17110,862,086 - 110,899,819 (-)NCBI
Celera7101,439,261 - 101,476,737 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ago2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621255
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.