Dmc1 (DNA meiotic recombinase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dmc1 (DNA meiotic recombinase 1) Rattus norvegicus
Analyze
Symbol: Dmc1
Name: DNA meiotic recombinase 1
RGD ID: 1307611
Description: Predicted to enable DNA binding activity; catalytic activity, acting on DNA; and identical protein binding activity. Predicted to be involved in DNA recombination and chromosome organization involved in meiotic cell cycle. Predicted to act upstream of or within germ cell development; meiosis I; and ovarian follicle development. Predicted to be located in chromosome, telomeric region and nucleus. Predicted to be active in condensed nuclear chromosome. Orthologous to human DMC1 (DNA meiotic recombinase 1); INTERACTS WITH bisphenol A; formaldehyde; trichloroethene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: disrupted meiotic cDNA 1 homolog; disrupted meiotic cDNA 1 homolog (yeast); DMC1 dosage suppressor of mck1 homolog; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast); Dmc1h; LOC362960; meiotic recombination protein DMC1/LIM15 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27111,124,888 - 111,167,465 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,124,888 - 111,167,952 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,872,520 - 112,915,092 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07115,096,054 - 115,138,630 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07115,065,426 - 115,108,004 (-)NCBIRnor_WKY
Rnor_6.07120,796,217 - 120,840,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,796,217 - 120,839,577 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,789,043 - 120,833,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,476,702 - 117,520,670 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,514,418 - 117,553,900 (+)NCBI
Celera7107,456,300 - 107,498,828 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12855593   PMID:15640358   PMID:15928951   PMID:17696610   PMID:18283110   PMID:18316482   PMID:20336070   PMID:20551173   PMID:22164254   PMID:22190708   PMID:22530760   PMID:22549958  
PMID:22711701   PMID:22899867   PMID:25416956   PMID:25502805   PMID:27760146   PMID:31515488  


Genomics

Comparative Map Data
Dmc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27111,124,888 - 111,167,465 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,124,888 - 111,167,952 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,872,520 - 112,915,092 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07115,096,054 - 115,138,630 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07115,065,426 - 115,108,004 (-)NCBIRnor_WKY
Rnor_6.07120,796,217 - 120,840,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,796,217 - 120,839,577 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,789,043 - 120,833,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,476,702 - 117,520,670 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,514,418 - 117,553,900 (+)NCBI
Celera7107,456,300 - 107,498,828 (-)NCBICelera
Cytogenetic Map7q34NCBI
DMC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,509,147 - 38,570,183 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2238,518,948 - 38,570,204 (-)EnsemblGRCh38hg38GRCh38
GRCh372238,914,953 - 38,966,188 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,244,900 - 37,296,135 (-)NCBINCBI36Build 36hg18NCBI36
Build 342237,239,453 - 37,290,689NCBI
Celera2222,720,538 - 22,771,771 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,880,996 - 21,931,997 (-)NCBIHuRef
CHM1_12238,873,735 - 38,925,022 (-)NCBICHM1_1
T2T-CHM13v2.02238,983,205 - 39,034,438 (-)NCBIT2T-CHM13v2.0
Dmc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,445,698 - 79,489,362 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,445,698 - 79,489,310 (-)EnsemblGRCm39 Ensembl
GRCm381579,561,497 - 79,605,159 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,561,497 - 79,605,109 (-)EnsemblGRCm38mm10GRCm38
MGSCv371579,391,930 - 79,435,514 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,388,755 - 79,432,339 (-)NCBIMGSCv36mm8
Celera1581,685,957 - 81,730,849 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.79NCBI
Dmc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,684,073 - 24,724,344 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,685,311 - 24,724,269 (-)NCBIChiLan1.0ChiLan1.0
DMC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12237,253,609 - 37,305,769 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,253,609 - 37,305,769 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02219,433,989 - 19,485,804 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
DMC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,228,662 - 26,265,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,230,428 - 26,264,820 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,184,319 - 26,220,549 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,019,568 - 27,056,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,019,605 - 27,056,226 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,741,166 - 26,777,610 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,052,510 - 27,089,151 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,229,297 - 27,265,765 (+)NCBIUU_Cfam_GSD_1.0
Dmc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,742,723 - 9,778,354 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364922,754,694 - 2,788,249 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DMC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,431,177 - 9,470,113 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,431,236 - 9,470,333 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,712,304 - 6,750,854 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DMC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,179,495 - 21,230,078 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,180,194 - 21,228,120 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,535,164 - 104,586,450 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dmc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247529,548,015 - 9,585,958 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247529,547,327 - 9,585,549 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH137666  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:426
Count of miRNA genes:239
Interacting mature miRNAs:279
Transcripts:ENSRNOT00000018526
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8
Low 68 21 11
Below cutoff 3 5 9 2 1 1 6 30 12 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000018526   ⟹   ENSRNOP00000018526
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7111,124,888 - 111,167,465 (-)Ensembl
Rnor_6.0 Ensembl7120,796,217 - 120,839,577 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099897   ⟹   ENSRNOP00000093514
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7111,124,888 - 111,167,952 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117960   ⟹   ENSRNOP00000093519
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7111,124,888 - 111,167,465 (-)Ensembl
RefSeq Acc Id: NM_001130567   ⟹   NP_001124039
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27111,124,888 - 111,167,465 (-)NCBI
Rnor_6.07120,796,217 - 120,839,577 (-)NCBI
Rnor_5.07120,789,043 - 120,833,600 (-)NCBI
RGSC_v3.47117,476,702 - 117,520,670 (+)RGD
Celera7107,456,300 - 107,498,828 (-)RGD
Sequence:
RefSeq Acc Id: XM_017594987   ⟹   XP_017450476
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27111,125,049 - 111,166,526 (-)NCBI
Rnor_6.07120,797,083 - 120,840,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079586   ⟹   XP_038935514
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27111,125,049 - 111,161,691 (-)NCBI
RefSeq Acc Id: XM_039079587   ⟹   XP_038935515
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27111,125,049 - 111,161,691 (-)NCBI
RefSeq Acc Id: XM_039079588   ⟹   XP_038935516
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27111,125,049 - 111,158,344 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001124039   ⟸   NM_001130567
- UniProtKB: D3ZJ85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450476   ⟸   XM_017594987
- Peptide Label: isoform X1
- UniProtKB: D3ZJ85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018526   ⟸   ENSRNOT00000018526
RefSeq Acc Id: XP_038935514   ⟸   XM_039079586
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038935515   ⟸   XM_039079587
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038935516   ⟸   XM_039079588
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000093514   ⟸   ENSRNOT00000099897
RefSeq Acc Id: ENSRNOP00000093519   ⟸   ENSRNOT00000117960
Protein Domains
RECA_2   RECA_3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJ85-F1-model_v2 AlphaFold D3ZJ85 1-340 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307611 AgrOrtholog
BioCyc Gene G2FUF-32756 BioCyc
Ensembl Genes ENSRNOG00000013807 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000018526 ENTREZGENE
  ENSRNOP00000018526.4 UniProtKB/TrEMBL
  ENSRNOP00000093514.1 UniProtKB/TrEMBL
  ENSRNOP00000093519.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018526 ENTREZGENE
  ENSRNOT00000018526.6 UniProtKB/TrEMBL
  ENSRNOT00000099897.1 UniProtKB/TrEMBL
  ENSRNOT00000117960.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  DMC1_rcmbase UniProtKB/TrEMBL
  DNA_recomb/repair_Rad51_C UniProtKB/TrEMBL
  DNA_recomb/repair_RecA-like UniProtKB/TrEMBL
  DNA_recomb_RecA/RadB_ATP-bd UniProtKB/TrEMBL
  DNA_repair_Rad51/TF_NusA_a-hlx UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Rad51_DMC1_RadA UniProtKB/TrEMBL
  RecA_monomer-monomer_interface UniProtKB/TrEMBL
KEGG Report rno:362960 UniProtKB/TrEMBL
NCBI Gene 362960 ENTREZGENE
Pfam Rad51 UniProtKB/TrEMBL
PhenoGen Dmc1 PhenoGen
PIRSF Rad51 UniProtKB/TrEMBL
PROSITE RECA_2 UniProtKB/TrEMBL
  RECA_3 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP Rad51_N UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
TIGRFAMs recomb_DMC1 UniProtKB/TrEMBL
UniProt A0A8I6AK83_RAT UniProtKB/TrEMBL
  A0A8I6GKP7_RAT UniProtKB/TrEMBL
  D3ZJ85 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-22 Dmc1  DNA meiotic recombinase 1  Dmc1  DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Dmc1  DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)  Dmc1h_predicted  disrupted meiotic cDNA 1 homolog (yeast) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dmc1h_predicted  disrupted meiotic cDNA 1 homolog (yeast) (predicted)    disrupted meiotic cDNA 1 homolog (predicted)  Name updated 1299863 APPROVED
2005-01-12 Dmc1h_predicted  disrupted meiotic cDNA 1 homolog (predicted)      Symbol and Name status set to approved 70820 APPROVED