 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
Molecular Pathway Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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Gene Annotator (Annotation Comparison) |
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Cellular Component
Molecular Function
Molecular Pathway AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Bruce BD and Churchich J, Eur J Biochem. 1997 May 1;245(3):738-44. |
| 2. | Demand J, etal., Mol Cell Biol 1998 Apr;18(4):2023-8. |
| 3. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | GOA data from the GO Consortium |
| 5. | Hohfeld J, etal., Cell 1995 Nov 17;83(4):589-98. |
| 6. | Irmer H and Hohfeld J, J Biol Chem. 1997 Jan 24;272(4):2230-5. |
| 7. | Li Z, etal., Nat Struct Mol Biol. 2013 Aug;20(8):929-35. doi: 10.1038/nsmb.2608. Epub 2013 Jun 30. |
| 8. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 9. | Prescott J and Coetzee GA, Cancer Lett. 2006 Jan 8;231(1):12-9. |
| 10. | RGD automated data pipeline |
| 11. | RGD automated import pipeline for gene-chemical interactions |
| 12. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 13. | Xilouri M and Stefanis L, Mol Cell Neurosci. 2015 May;66(Pt A):29-36. doi: 10.1016/j.mcn.2015.01.003. Epub 2015 Feb 25. |
| 14. | Zhang QG, etal., Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):E617-24. doi: 10.1073/pnas.1104391108. Epub 2011 Aug 1. |
References - uncuratedGenomics
Candidate Gene StatusComparative Map Data| St13 (Rattus norvegicus - Norway rat) |
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| ST13 (Homo sapiens - human) |
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| St13 (Mus musculus - house mouse) |
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| St13 (Chinchilla lanigera - long-tailed chinchilla) |
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| ST13 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ST13 (Canis lupus familiaris - dog) |
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| St13 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ST13 (Sus scrofa - pig) |
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| ST13 (Chlorocebus sabaeus - African green monkey) |
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| St13 (Heterocephalus glaber - naked mole-rat) |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
| Low | |||||||||||||
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View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_031122 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07058532 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07058533 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07058534 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051846 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051847 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC078804 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473950 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ212434 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ215747 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ228746 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| X82021 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000025925 ⟹ ENSRNOP00000025925 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_031122 ⟹ NP_112384 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GCGTCGACGGGCTTGGCATCGGGCCTCCGCAGCCGCCCACCGCCAGAAGCTTCCAGCCTCACCAhide sequence |
Protein Sequences| Protein RefSeqs | NP_112384 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAH78804 | (Get FASTA) | NCBI Sequence Viewer |
| CAA57546 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM15726 | (Get FASTA) | NCBI Sequence Viewer | |
| P50503 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_112384 ⟸ NM_031122 |
| - UniProtKB: | P50503 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MDPRKVSELRAFVKMCRQDPSVLHTEEMRFLREWVESMGGKVPPATHKAKSEENTKEEKRDKTThide sequence |
| RefSeq Acc Id: | ENSRNOP00000025925 ⟸ ENSRNOT00000025925 |
Protein Domains
STI1
TranscriptomePromoters| RGD ID: | 13695508 | ||||||||
| Promoter ID: | EPDNEW_R6033 | ||||||||
| Type: | initiation region | ||||||||
| Name: | St13_1 | ||||||||
| Description: | ST13, Hsp70 interacting protein | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: Rnor_5.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 7 | 122584152 | 122584153 | G | A | snv | F344/NCrl (KNAW), F344/NRrrc (SOLiD) (KNAW), F344/NHsd (KNAW), F344/NRrrc (Illumina) (KNAW), BUF/N (KNAW), DA/BklArbNsi (KNAW) |
Assembly: Rnor_6.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 7 | 122607606 | 122607607 | G | A | snv | Buf/N (MCW), F344/NRrrc (MCW) |
Assembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 7 | 119700811 | 119700812 | G | A | snv | F344/NRrrc (KNAW), F344/NHsd (ICAHN), F344/NCrl (ICL), DA/BklArbNsi (ICAHN), HCR/1Mco (UMich), HCR/2Mco (UMich), BUF/N (KNAW), LCR/2Mco (UMich) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:621312 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000019070 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000025925 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000025925 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Gene3D-CATH | 1.25.40.10 | UniProtKB/Swiss-Prot |
| IMAGE_CLONE | IMAGE:7109473 | IMAGE-MGC_LOAD |
| InterPro | Hip_N | UniProtKB/Swiss-Prot |
| STI1 | UniProtKB/Swiss-Prot | |
| STI1_HS-bd | UniProtKB/Swiss-Prot | |
| TPR-contain_dom | UniProtKB/Swiss-Prot | |
| TPR-like_helical_dom_sf | UniProtKB/Swiss-Prot | |
| TPR_repeat | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:81800 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:93379 | IMAGE-MGC_LOAD |
| NCBI Gene | 81800 | ENTREZGENE |
| Pfam | HipN | UniProtKB/Swiss-Prot |
| STI1 | UniProtKB/Swiss-Prot | |
| PhenoGen | St13 | PhenoGen |
| PROSITE | TPR | UniProtKB/Swiss-Prot |
| TPR_REGION | UniProtKB/Swiss-Prot | |
| SMART | STI1 | UniProtKB/Swiss-Prot |
| TPR | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF48452 | UniProtKB/Swiss-Prot |
| UniGene | Rn.119613 | ENTREZGENE |
| Rn.8796 | ENTREZGENE | |
| UniProt | F10A1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2017-03-21 | St13 | ST13, Hsp70 interacting protein | St13 | suppression of tumorigenicity 13 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2004-12-14 | St13 | suppression of tumorigenicity 13 | suppression of tumorigenicity 13 (colon carcinoma) Hsp70-interacting protein | Name updated | 1299863 | APPROVED | |
| 2002-08-07 | St13 | suppression of tumorigenicity 13 (colon carcinoma) Hsp70-interacting protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_domains | contains tetratricopeptide repeats | 729993 |
| gene_function | binds the ATPase domains of at least two Hsc70 molecules | 729993 |
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| More on St13 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 621312 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-03-04 |
| Status: | ACTIVE |
