ST13 (ST13 Hsp70 interacting protein) - Rat Genome Database

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Gene: ST13 (ST13 Hsp70 interacting protein) Homo sapiens
Analyze
Symbol: ST13
Name: ST13 Hsp70 interacting protein
RGD ID: 733794
HGNC Page HGNC
Description: Predicted to have heat shock protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein-containing complex assembly. Localizes to cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AAG2; aging-associated protein 2; FAM10A1; FAM10A4; FLJ27260; heat shock 70kD protein binding protein; HIP; HOP; hsc70-interacting protein; Hsp70-interacting protein; HSPABP; HSPABP1; MGC129952; P48; PRO0786; progesterone receptor-associated p48 protein; putative tumor suppressor ST13; renal carcinoma antigen NY-REN-33; SNC6; suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein); suppression of tumorigenicity 13 (colon carcinoma) hsp70-interacting protein; suppression of tumorigenicity 13 protein; testis secretory sperm-binding protein Li 233m
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: ST13P1   ST13P10   ST13P11   ST13P12   ST13P13   ST13P14   ST13P15   ST13P16   ST13P17   ST13P18   ST13P19   ST13P2   ST13P20   ST13P21   ST13P22   ST13P3   ST13P4   ST13P5   ST13P6   ST13P7   ST13P8   ST13P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2240,824,535 - 40,856,639 (-)EnsemblGRCh38hg38GRCh38
GRCh382240,824,535 - 40,856,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,220,539 - 41,252,643 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,550,545 - 39,582,633 (-)NCBINCBI36hg18NCBI36
Build 342239,545,102 - 39,577,187NCBI
Celera2225,024,269 - 25,056,358 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,182,572 - 24,215,046 (-)NCBIHuRef
CHM1_12241,179,290 - 41,211,764 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
acrolein  (EXP)
acrylamide  (EXP)
albendazole  (EXP)
alpha-pinene  (EXP)
amiodarone  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arsenous acid  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
butanal  (EXP)
cadmium dichloride  (EXP)
caffeine  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clomipramine  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (EXP)
CU-O LINKAGE  (EXP)
cyclophosphamide  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
disodium selenite  (EXP)
doxorubicin  (EXP)
elemental selenium  (ISO)
enzyme inhibitor  (EXP)
ethanol  (ISO)
felbamate  (ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (ISO)
gabapentin  (ISO)
gamma-linolenic acid  (EXP)
imipramine  (ISO)
ivermectin  (EXP)
ketoconazole  (ISO)
kojic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
methamphetamine  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
ochratoxin A  (EXP)
ozone  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenytoin  (ISO)
quercetin  (EXP)
resveratrol  (EXP)
SCH 23390  (ISO)
selenium atom  (ISO)
Soman  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8721986   PMID:8887650   PMID:8889548   PMID:9292708   PMID:9387309   PMID:9452498   PMID:9594214   PMID:9857057   PMID:9925927   PMID:10508479   PMID:10591208   PMID:10642522  
PMID:10702249   PMID:10781595   PMID:11093761   PMID:11559757   PMID:11687574   PMID:11741305   PMID:11751889   PMID:12477932   PMID:15071092   PMID:15174051   PMID:15231748   PMID:15461802  
PMID:15489334   PMID:15637739   PMID:15647277   PMID:15664198   PMID:15845543   PMID:16169070   PMID:16358374   PMID:16807684   PMID:17013759   PMID:17081983   PMID:17324930   PMID:17535810  
PMID:18654987   PMID:19056867   PMID:19322201   PMID:19738201   PMID:19875381   PMID:20193743   PMID:20458337   PMID:20512919   PMID:20534503   PMID:20936779   PMID:21163940   PMID:21240662  
PMID:21319273   PMID:21728385   PMID:21767636   PMID:21873635   PMID:21875946   PMID:21900206   PMID:22504172   PMID:22863883   PMID:22939629   PMID:23125081   PMID:23376485   PMID:23383273  
PMID:23414517   PMID:23824909   PMID:25036637   PMID:25192599   PMID:25616159   PMID:25864199   PMID:25921289   PMID:25959826   PMID:26344197   PMID:26414348   PMID:26549023   PMID:26641092  
PMID:27371349   PMID:27708256   PMID:28298427   PMID:28443643   PMID:28700943   PMID:29395067   PMID:29845934   PMID:30442662   PMID:30463901   PMID:30585729   PMID:30833792   PMID:30948266  
PMID:31300519   PMID:31995728   PMID:32203420   PMID:32791689   PMID:32814053   PMID:32877691  


Genomics

Comparative Map Data
ST13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2240,824,535 - 40,856,639 (-)EnsemblGRCh38hg38GRCh38
GRCh382240,824,535 - 40,856,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,220,539 - 41,252,643 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,550,545 - 39,582,633 (-)NCBINCBI36hg18NCBI36
Build 342239,545,102 - 39,577,187NCBI
Celera2225,024,269 - 25,056,358 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,182,572 - 24,215,046 (-)NCBIHuRef
CHM1_12241,179,290 - 41,211,764 (-)NCBICHM1_1
St13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,247,869 - 81,283,951 (-)NCBIGRCm39mm39
GRCm39 Ensembl1581,247,870 - 81,284,278 (-)Ensembl
GRCm381581,365,044 - 81,399,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,363,669 - 81,400,077 (-)EnsemblGRCm38mm10GRCm38
MGSCv371581,195,474 - 81,230,124 (-)NCBIGRCm37mm9NCBIm37
MGSCv361581,192,299 - 81,226,949 (-)NCBImm8
Celera1583,483,114 - 83,517,731 (-)NCBICelera
Cytogenetic Map15E1NCBI
St13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27112,891,007 - 112,925,727 (-)NCBI
Rnor_6.0 Ensembl7122,585,771 - 122,635,731 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07122,585,770 - 122,635,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07122,561,392 - 122,612,277 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,694,123 - 119,728,936 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17119,728,353 - 119,763,166 (-)NCBI
Celera7109,210,016 - 109,245,175 (-)NCBICelera
Cytogenetic Map7q34NCBI
St13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,476,469 - 26,507,671 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,478,579 - 26,507,671 (-)NCBIChiLan1.0ChiLan1.0
ST13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12239,815,337 - 39,848,049 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2239,815,337 - 39,848,049 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02221,719,713 - 21,751,912 (-)NCBIMhudiblu_PPA_v0panPan3
ST13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,379,997 - 24,411,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1024,379,997 - 24,411,766 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1024,314,161 - 24,345,833 (+)NCBI
ROS_Cfam_1.01025,127,715 - 25,159,445 (+)NCBI
UMICH_Zoey_3.11024,842,961 - 24,874,594 (+)NCBI
UNSW_CanFamBas_1.01025,163,854 - 25,195,541 (+)NCBI
UU_Cfam_GSD_1.01025,338,235 - 25,369,960 (+)NCBI
St13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,966,770 - 7,998,826 (+)NCBI
SpeTri2.0NW_004936492976,928 - 1,010,748 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,577,970 - 7,617,762 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,583,074 - 7,617,766 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,763,686 - 4,796,346 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ST13
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11923,373,970 - 23,413,054 (-)NCBI
ChlSab1.1 Ensembl1923,375,723 - 23,412,742 (-)Ensembl
St13
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247527,634,910 - 7,663,135 (+)NCBI

Position Markers
RH92006  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372241,253,755 - 41,253,908UniSTSGRCh37
Build 362239,583,701 - 39,583,854RGDNCBI36
Celera2225,057,426 - 25,057,579RGD
Cytogenetic Map22q13.2UniSTS
HuRef2224,215,789 - 24,215,942UniSTS
GeneMap99-GB4 RH Map22118.5UniSTS
D22S980E.1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372241,221,320 - 41,221,442UniSTSGRCh37
GRCh372188,692,282 - 188,692,409UniSTSGRCh37
Build 362188,400,527 - 188,400,654RGDNCBI36
Celera2182,288,054 - 182,288,181RGD
Celera2225,024,990 - 25,025,112UniSTS
Cytogenetic Map22q13.2UniSTS
HuRef2224,183,353 - 24,183,475UniSTS
HuRef2180,551,560 - 180,551,687UniSTS
RH118753  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377132,822,277 - 132,822,557UniSTSGRCh37
Build 367132,472,817 - 132,473,097RGDNCBI36
Celera7127,573,819 - 127,574,099RGD
HuRef7127,138,133 - 127,138,413UniSTS
CRA_TCAGchr7v27132,161,830 - 132,162,110UniSTS
TNG Radiation Hybrid Map760181.0UniSTS
ST13_2133  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372241,220,496 - 41,221,348UniSTSGRCh37
Build 362239,550,442 - 39,551,294RGDNCBI36
Celera2225,024,166 - 25,025,018RGD
HuRef2224,182,529 - 24,183,381UniSTS
G19794  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372241,221,207 - 41,221,427UniSTSGRCh37
Build 362239,551,153 - 39,551,373RGDNCBI36
Celera2225,024,877 - 25,025,097RGD
Cytogenetic Map22q13.2UniSTS
HuRef2224,183,240 - 24,183,460UniSTS
A001Y34  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372241,221,207 - 41,221,427UniSTSGRCh37
Build 362239,551,153 - 39,551,373RGDNCBI36
Celera2225,024,877 - 25,025,097RGD
Cytogenetic Map22q13.2UniSTS
HuRef2224,183,240 - 24,183,460UniSTS
GeneMap99-GB4 RH Map22137.41UniSTS
NCBI RH Map22195.9UniSTS
D12S1174E  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q13.2UniSTS
GDB:451586  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q13.2UniSTS
UniSTS:484527  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378134,420,231 - 134,421,385UniSTSGRCh37
GRCh377132,854,140 - 132,855,290UniSTSGRCh37
Celera7127,605,671 - 127,606,822UniSTS
Celera8130,597,615 - 130,598,769UniSTS
HuRef7127,169,806 - 127,170,957UniSTS
HuRef8129,739,197 - 129,740,350UniSTS
CRA_TCAGchr7v27132,193,531 - 132,194,682UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2021
Count of miRNA genes:989
Interacting mature miRNAs:1157
Transcripts:ENST00000216218, ENST00000411695, ENST00000413424, ENST00000455824, ENST00000480048, ENST00000495652
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1 4
Medium 2439 2943 1726 624 1947 465 4356 2154 3734 417 1456 1613 175 1 1204 2788 6 2
Low 48 4 43 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001278589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF116650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK130770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY513286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY826824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY826825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC071629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC121107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC121108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC139724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG706239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM679025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR456586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM005646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U28918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z98048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000216218   ⟹   ENSP00000216218
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2240,824,535 - 40,856,639 (-)Ensembl
RefSeq Acc Id: ENST00000411695   ⟹   ENSP00000392067
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2240,832,652 - 40,854,598 (-)Ensembl
RefSeq Acc Id: ENST00000413424   ⟹   ENSP00000412049
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2240,830,875 - 40,844,890 (-)Ensembl
RefSeq Acc Id: ENST00000455824   ⟹   ENSP00000397062
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2240,827,221 - 40,856,616 (-)Ensembl
RefSeq Acc Id: ENST00000480048
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2240,827,150 - 40,835,905 (-)Ensembl
RefSeq Acc Id: ENST00000495652
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2240,835,393 - 40,835,949 (-)Ensembl
RefSeq Acc Id: ENST00000620312   ⟹   ENSP00000481328
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2240,826,421 - 40,856,565 (-)Ensembl
RefSeq Acc Id: NM_001278589   ⟹   NP_001265518
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382240,824,535 - 40,856,639 (-)NCBI
HuRef2224,182,572 - 24,215,046 (-)NCBI
CHM1_12241,179,290 - 41,211,764 (-)NCBI
Sequence:
RefSeq Acc Id: NM_003932   ⟹   NP_003923
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382240,824,535 - 40,856,639 (-)NCBI
GRCh372241,220,539 - 41,253,012 (-)NCBI
Build 362239,550,545 - 39,582,633 (-)NCBI Archive
HuRef2224,182,572 - 24,215,046 (-)NCBI
CHM1_12241,179,290 - 41,211,764 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_003923   ⟸   NM_003932
- Peptide Label: isoform 1
- UniProtKB: P50502 (UniProtKB/Swiss-Prot),   A0A140VKA6 (UniProtKB/TrEMBL),   Q0IJ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001265518   ⟸   NM_001278589
- Peptide Label: isoform 2
- UniProtKB: B4E0U6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000481328   ⟸   ENST00000620312
RefSeq Acc Id: ENSP00000392067   ⟸   ENST00000411695
RefSeq Acc Id: ENSP00000216218   ⟸   ENST00000216218
RefSeq Acc Id: ENSP00000412049   ⟸   ENST00000413424
RefSeq Acc Id: ENSP00000397062   ⟸   ENST00000455824
Protein Domains
HipN   STI1   TPR_REGION

Promoters
RGD ID:6800396
Promoter ID:HG_KWN:42944
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Jurkat
Transcripts:OTTHUMT00000321762
Position:
Human AssemblyChrPosition (strand)Source
Build 362239,571,436 - 39,571,936 (-)MPROMDB
RGD ID:6800496
Promoter ID:HG_KWN:42946
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000321759,   OTTHUMT00000321760,   OTTHUMT00000322201,   OTTHUMT00000322205,   UC003AZF.1,   UC003AZG.1,   UC003AZI.1
Position:
Human AssemblyChrPosition (strand)Source
Build 362239,582,076 - 39,583,132 (+)MPROMDB
RGD ID:6850702
Promoter ID:EP73145
Type:initiation region
Name:HS_ST13
Description:Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70interacting protein).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 362239,582,589 - 39,582,649EPD
RGD ID:13604222
Promoter ID:EPDNEW_H28295
Type:initiation region
Name:ST13_1
Description:ST13, Hsp70 interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28298  EPDNEW_H28323  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382240,856,639 - 40,856,699EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 22q13.2(chr22:40832364-41076954)x1 copy number loss See cases [RCV000051369] Chr22:40832364..41076954 [GRCh38]
Chr22:41228368..41472958 [GRCh37]
Chr22:39558314..39802904 [NCBI36]
Chr22:22q13.2
pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:37061769-50738932)x3 copy number gain See cases [RCV000051684] Chr22:37061769..50738932 [GRCh38]
Chr22:37457809..51177360 [GRCh37]
Chr22:35787755..49524226 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q13.1-13.2(chr22:37721797-40860953)x3 copy number gain See cases [RCV000051685] Chr22:37721797..40860953 [GRCh38]
Chr22:38117804..41256957 [GRCh37]
Chr22:36447750..39586903 [NCBI36]
Chr22:22q13.1-13.2
pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:33768441-50739977)x3 copy number gain See cases [RCV000051682] Chr22:33768441..50739977 [GRCh38]
Chr22:34164428..51178405 [GRCh37]
Chr22:32494428..49525271 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 copy number gain See cases [RCV000133646] Chr22:16916608..50739836 [GRCh38]
Chr22:17397498..51178264 [GRCh37]
Chr22:15777498..49525130 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 copy number gain See cases [RCV000134730] Chr22:16916743..50739785 [GRCh38]
Chr22:17397633..51178213 [GRCh37]
Chr22:15777633..49525079 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q13.1-13.33(chr22:40202014-50735806)x3 copy number gain See cases [RCV000134513] Chr22:40202014..50735806 [GRCh38]
Chr22:40598018..51174234 [GRCh37]
Chr22:38927964..49521100 [NCBI36]
Chr22:22q13.1-13.33
pathogenic
GRCh38/hg38 22q13.2(chr22:40769910-41360090)x3 copy number gain See cases [RCV000134514] Chr22:40769910..41360090 [GRCh38]
Chr22:41165914..41756094 [GRCh37]
Chr22:39495860..40086040 [NCBI36]
Chr22:22q13.2
uncertain significance
GRCh38/hg38 22q13.2(chr22:40732506-40892856)x3 copy number gain See cases [RCV000135853] Chr22:40732506..40892856 [GRCh38]
Chr22:41128510..41288860 [GRCh37]
Chr22:39458456..39618806 [NCBI36]
Chr22:22q13.2
benign
GRCh38/hg38 22q13.1-13.2(chr22:40431454-40934348)x3 copy number gain See cases [RCV000137666] Chr22:40431454..40934348 [GRCh38]
Chr22:40827458..41330352 [GRCh37]
Chr22:39157404..39660298 [NCBI36]
Chr22:22q13.1-13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237518)x3 copy number gain See cases [RCV000240091] Chr22:16054691..51237518 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q12.3-13.33(chr22:35728929-51220961)x3 copy number gain See cases [RCV000240469] Chr22:35728929..51220961 [GRCh37]
Chr22:22q12.3-13.33
pathogenic
GRCh37/hg19 22q13.1-13.33(chr22:40425714-51220961)x3 copy number gain See cases [RCV000240459] Chr22:40425714..51220961 [GRCh37]
Chr22:22q13.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51220902)x3 copy number gain See cases [RCV000446956] Chr22:16054691..51220902 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:41223048-41278147)x3 copy number gain See cases [RCV000447587] Chr22:41223048..41278147 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237463)x3 copy number gain See cases [RCV000448847] Chr22:16054691..51237463 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.1-13.2(chr22:40233644-41655673)x3 copy number gain See cases [RCV000448955] Chr22:40233644..41655673 [GRCh37]
Chr22:22q13.1-13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838) copy number gain See cases [RCV000510873] Chr22:16888900..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838)x3 copy number gain See cases [RCV000512333] Chr22:16888900..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054667-51243435)x3 copy number gain not provided [RCV000741689] Chr22:16054667..51243435 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51195728)x3 copy number gain not provided [RCV000741691] Chr22:16114244..51195728 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51211392)x3 copy number gain not provided [RCV000741692] Chr22:16114244..51211392 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.1-13.33(chr22:40502364-51197838)x3 copy number gain not provided [RCV001007502] Chr22:40502364..51197838 [GRCh37]
Chr22:22q13.1-13.33
pathogenic
GRCh37/hg19 22q12.2-13.33(chr22:30654764-51197838)x3 copy number gain not provided [RCV001007181] Chr22:30654764..51197838 [GRCh37]
Chr22:22q12.2-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16888899-51197838)x3 copy number gain not provided [RCV000846344] Chr22:16888899..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
NM_003932.5(ST13):c.875A>G (p.Asn292Ser) single nucleotide variant not provided [RCV000887299] Chr22:40827202 [GRCh38]
Chr22:41223206 [GRCh37]
Chr22:22q13.2
benign
GRCh37/hg19 22q13.1-13.2(chr22:40665986-41370008)x3 copy number gain not provided [RCV001007190] Chr22:40665986..41370008 [GRCh37]
Chr22:22q13.1-13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16197005-51224252)x3 copy number gain See cases [RCV001263056] Chr22:16197005..51224252 [GRCh37]
Chr22:22q11.1-13.33
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11343 AgrOrtholog
COSMIC ST13 COSMIC
Ensembl Genes ENSG00000100380 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000216218 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000392067 UniProtKB/TrEMBL
  ENSP00000397062 UniProtKB/TrEMBL
  ENSP00000412049 UniProtKB/TrEMBL
  ENSP00000481328 UniProtKB/TrEMBL
Ensembl Transcript ENST00000216218 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000411695 UniProtKB/TrEMBL
  ENST00000413424 UniProtKB/TrEMBL
  ENST00000455824 UniProtKB/TrEMBL
  ENST00000620312 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000100380 GTEx
HGNC ID HGNC:11343 ENTREZGENE
Human Proteome Map ST13 Human Proteome Map
InterPro Hip_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STI1_HS-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-contain_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:6767 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 6767 ENTREZGENE
OMIM 606796 OMIM
Pfam HipN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
PharmGKB PA36167 PharmGKB
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART STI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140VKA6 ENTREZGENE, UniProtKB/TrEMBL
  B4E0U6 ENTREZGENE, UniProtKB/TrEMBL
  F10A1_HUMAN UniProtKB/Swiss-Prot
  F6VDH7_HUMAN UniProtKB/TrEMBL
  F8WAQ7_HUMAN UniProtKB/TrEMBL
  H7C3I1_HUMAN UniProtKB/TrEMBL
  P50502 ENTREZGENE
  Q0IJ56 ENTREZGENE, UniProtKB/TrEMBL
  Q3KNR6_HUMAN UniProtKB/TrEMBL
  Q9P1I4_HUMAN UniProtKB/TrEMBL
UniProt Secondary O14999 UniProtKB/Swiss-Prot
  Q2TU77 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 ST13  ST13 Hsp70 interacting protein    ST13, Hsp70 interacting protein  Symbol and/or name change 5135510 APPROVED
2017-03-07 ST13  ST13, Hsp70 interacting protein    suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)  Symbol and/or name change 5135510 APPROVED
2011-08-16 ST13  suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)  ST13  suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)  Symbol and/or name change 5135510 APPROVED