Prph (peripherin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Prph (peripherin) Rattus norvegicus
Analyze
Symbol: Prph
Name: peripherin
RGD ID: 3414
Description: Predicted to be a structural constituent of cytoskeleton. Involved in intermediate filament cytoskeleton organization. Located in neuronal cell body; terminal bouton; and type III intermediate filament. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 1. Orthologous to human PRPH (peripherin); PARTICIPATES IN amyotrophic lateral sclerosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Perf; peripherin 1; Prph1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27130,218,149 - 130,222,136 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,218,357 - 130,222,136 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,028,577 - 132,032,350 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07134,254,151 - 134,257,924 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07134,166,656 - 134,170,429 (+)NCBIRnor_WKY
Rnor_6.07140,742,406 - 140,746,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,742,418 - 140,746,197 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,247,151 - 115,251,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,836,152 - 137,839,931 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17137,912,601 - 137,916,363 (+)NCBI
Celera7126,703,099 - 126,706,878 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Correlation between genetic and cytogenetic maps of the rat. Andoh Y, etal., Mamm Genome 1998 Apr;9(4):287-93.
2. Heterodimeric associations between neuronal intermediate filament proteins. Athlan ES and Mushynski WE, J Biol Chem. 1997 Dec 5;272(49):31073-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Translation initiation and assembly of peripherin in cultured cells. Ho CL, etal., Eur J Cell Biol 1995 Oct;68(2):103-12.
6. The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons. Leung CL, etal., J Cell Biol. 1999 Feb 8;144(3):435-46.
7. Peripherin immunoreactivity labels small diameter vestibular 'bouton' afferents in rodents. Lysakowski A, etal., Hear Res. 1999 Jul;133(1-2):149-54.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members. Shah NM, etal., Cell. 1996 May 3;85(3):331-43.
16. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
17. Structure of the gene encoding peripherin, an NGF-regulated neuronal-specific type III intermediate filament protein. Thompson MA and Ziff EB, Neuron 1989 Jan;2(1):1043-53.
Additional References at PubMed
PMID:3272173   PMID:3339087   PMID:3418352   PMID:9453548   PMID:10221457   PMID:10414956   PMID:12107488   PMID:12477932   PMID:12642616   PMID:16029194   PMID:17268851   PMID:17569669  
PMID:17964735   PMID:18434031   PMID:19913522   PMID:19946888   PMID:22183407   PMID:23106098   PMID:23533145   PMID:24582971   PMID:24625528   PMID:25113441  


Genomics

Comparative Map Data
Prph
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27130,218,149 - 130,222,136 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,218,357 - 130,222,136 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,028,577 - 132,032,350 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07134,254,151 - 134,257,924 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07134,166,656 - 134,170,429 (+)NCBIRnor_WKY
Rnor_6.07140,742,406 - 140,746,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,742,418 - 140,746,197 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,247,151 - 115,251,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,836,152 - 137,839,931 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17137,912,601 - 137,916,363 (+)NCBI
Celera7126,703,099 - 126,706,878 (+)NCBICelera
Cytogenetic Map7q36NCBI
PRPH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,295,147 - 49,298,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1249,295,147 - 49,298,686 (+)EnsemblGRCh38hg38GRCh38
GRCh371249,688,930 - 49,692,469 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,975,176 - 47,978,748 (+)NCBINCBI36Build 36hg18NCBI36
Build 341247,975,250 - 47,978,732NCBI
Celera1248,481,731 - 48,485,303 (+)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1246,719,777 - 46,723,549 (+)NCBIHuRef
CHM1_11249,654,607 - 49,658,179 (+)NCBICHM1_1
T2T-CHM13v2.01249,257,338 - 49,260,877 (+)NCBIT2T-CHM13v2.0
Prph
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,951,452 - 98,956,859 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,953,055 - 98,956,859 (+)EnsemblGRCm39 Ensembl
GRCm381599,053,579 - 99,058,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,055,174 - 99,058,978 (+)EnsemblGRCm38mm10GRCm38
MGSCv371598,885,605 - 98,889,409 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361598,883,241 - 98,886,704 (+)NCBIMGSCv36mm8
Celera15101,208,902 - 101,212,694 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1555.72NCBI
Prph
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555008,107,847 - 8,117,290 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555008,106,371 - 8,117,221 (+)NCBIChiLan1.0ChiLan1.0
PRPH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11240,337,626 - 40,342,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,337,626 - 40,342,611 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01239,451,832 - 39,456,800 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PRPH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,314,815 - 5,320,270 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,314,807 - 5,320,089 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,928,170 - 40,941,768 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0275,366,381 - 5,380,010 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,366,389 - 5,371,465 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,331,470 - 5,344,950 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,320,895 - 5,334,284 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,321,186 - 41,334,583 (+)NCBIUU_Cfam_GSD_1.0
Prph
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,113,872 - 66,118,583 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,047,253 - 7,051,007 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365127,046,275 - 7,050,958 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRPH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,285,294 - 15,288,798 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,283,399 - 15,288,800 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,146,476 - 16,176,379 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRPH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,520,506 - 45,525,548 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1145,522,059 - 45,525,212 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037200,604,408 - 200,624,925 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prph
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,873,690 - 2,877,238 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,873,689 - 2,877,335 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prph
24 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:49
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000021010
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
D7Wox24  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X115,250,056 - 115,250,191NCBIRnor5.0
RGSC_v3.47137,838,850 - 137,838,984RGDRGSC3.4
RGSC_v3.17137,915,287 - 137,915,421RGD
RH 3.4 Map71132.72UniSTS
RH 3.4 Map71132.72RGD
RH 2.0 Map7825.6RGD
Cytogenetic Map7q34UniSTS
D7Mit9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,221,005 - 130,221,281 (+)MAPPERmRatBN7.2
Rnor_6.07140,745,067 - 140,745,342NCBIRnor6.0
Rnor_5.0X115,250,008 - 115,250,283UniSTSRnor5.0
RGSC_v3.47137,838,800 - 137,839,076RGDRGSC3.4
RGSC_v3.47137,838,801 - 137,839,076UniSTSRGSC3.4
RGSC_v3.17137,915,237 - 137,915,513RGD
Celera7126,705,748 - 126,706,023UniSTS
RH 3.4 Map71075.1UniSTS
RH 3.4 Map71075.1RGD
RH 2.0 Map7786.2RGD
SHRSP x BN Map786.2099RGD
Cytogenetic Map7q34UniSTS
RH133745  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,221,976 - 130,222,134 (+)MAPPERmRatBN7.2
Rnor_6.07140,746,038 - 140,746,195NCBIRnor6.0
Rnor_5.0X115,250,979 - 115,251,136UniSTSRnor5.0
RGSC_v3.47137,839,772 - 137,839,929UniSTSRGSC3.4
Celera7126,706,719 - 126,706,876UniSTS
RH 3.4 Map71087.6UniSTS
Cytogenetic Map7q34UniSTS
RH94483  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,222,046 - 130,222,222 (+)MAPPERmRatBN7.2
Rnor_6.07140,746,108 - 140,746,283NCBIRnor6.0
Rnor_5.0X115,251,049 - 115,251,224UniSTSRnor5.0
RGSC_v3.47137,839,842 - 137,840,017UniSTSRGSC3.4
Celera7126,706,789 - 126,706,964UniSTS
Cytogenetic Map7q34UniSTS
PMC104164P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,219,958 - 130,220,612 (+)MAPPERmRatBN7.2
Rnor_6.07140,744,020 - 140,744,673NCBIRnor6.0
Rnor_5.0X115,248,961 - 115,249,614UniSTSRnor5.0
RGSC_v3.47137,837,754 - 137,838,407UniSTSRGSC3.4
Celera7126,704,701 - 126,705,354UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 8 38 20
Low 1 35 51 38 14 38 8 11 36 32 17 11 8
Below cutoff 6 3 5 3 3 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000089211   ⟹   ENSRNOP00000072008
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,218,357 - 130,222,136 (+)Ensembl
Rnor_6.0 Ensembl7140,742,418 - 140,746,197 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094354   ⟹   ENSRNOP00000097710
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,218,357 - 130,222,136 (+)Ensembl
RefSeq Acc Id: NM_012633   ⟹   NP_036765
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,218,357 - 130,222,136 (+)NCBI
Rnor_6.07140,742,418 - 140,746,197 (+)NCBI
Rnor_5.0X115,247,151 - 115,251,138 (+)NCBI
RGSC_v3.47137,836,152 - 137,839,931 (+)RGD
Celera7126,703,099 - 126,706,878 (+)RGD
Sequence:
RefSeq Acc Id: XM_006257321   ⟹   XP_006257383
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,218,149 - 130,222,136 (+)NCBI
Rnor_6.07140,742,406 - 140,746,193 (+)NCBI
Rnor_5.0X115,247,151 - 115,251,138 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006257322   ⟹   XP_006257384
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,218,149 - 130,222,136 (+)NCBI
Rnor_6.07140,742,406 - 140,746,193 (+)NCBI
Rnor_5.0X115,247,151 - 115,251,138 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765669   ⟹   XP_008763891
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,218,149 - 130,222,136 (+)NCBI
Rnor_6.07140,742,406 - 140,746,197 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078428   ⟹   XP_038934356
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,218,149 - 130,222,136 (+)NCBI
RefSeq Acc Id: XM_039078429   ⟹   XP_038934357
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,218,149 - 130,222,136 (+)NCBI
RefSeq Acc Id: XM_039078430   ⟹   XP_038934358
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,218,149 - 130,220,927 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_036765   ⟸   NM_012633
- Sequence:
RefSeq Acc Id: XP_006257383   ⟸   XM_006257321
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006257384   ⟸   XM_006257322
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008763891   ⟸   XM_008765669
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AT59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072008   ⟸   ENSRNOT00000089211
RefSeq Acc Id: XP_038934356   ⟸   XM_039078428
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934357   ⟸   XM_039078429
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038934358   ⟸   XM_039078430
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000097710   ⟸   ENSRNOT00000094354
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P21807-F1-model_v2 AlphaFold P21807 1-468 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695638
Promoter ID:EPDNEW_R6163
Type:single initiation site
Name:Prph_1
Description:peripherin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07140,742,412 - 140,742,472EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3414 AgrOrtholog
BioCyc Gene G2FUF-32088 BioCyc
Ensembl Genes ENSRNOG00000052880 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000072008 ENTREZGENE
  ENSRNOP00000072008.1 UniProtKB/TrEMBL
  ENSRNOP00000097710 ENTREZGENE
  ENSRNOP00000097710.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000089211 ENTREZGENE
  ENSRNOT00000089211.2 UniProtKB/TrEMBL
  ENSRNOT00000094354 ENTREZGENE
  ENSRNOT00000094354.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7936222 IMAGE-MGC_LOAD
InterPro IF_conserved UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Intermed_filament_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Keratin_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRPH/Plasticin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24688 UniProtKB/TrEMBL
MGC_CLONE MGC:124633 IMAGE-MGC_LOAD
NCBI Gene 24688 ENTREZGENE
PANTHER PTHR45652:SF14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Filament_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prph PhenoGen
PRINTS TYPE1KERATIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC228365
UniProt A0A8I6AT59 ENTREZGENE, UniProtKB/TrEMBL
  F1M7P4_RAT UniProtKB/TrEMBL
  P21807 ENTREZGENE, UniProtKB/Swiss-Prot
  Q496Z5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-17 Prph  peripherin  Prph1  peripherin 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Prph1  peripherin 1  Prph  Peripherin  Symbol and Name updated 629477 APPROVED
2002-06-10 Prph  Peripherin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain 633740
gene_regulation expression is regulated by NGF 633741