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Gene: Sp7 (Sp7 transcription factor) Rattus norvegicus
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Symbol: Sp7
Name: Sp7 transcription factor
Description: Predicted to have DEAD/H-box RNA helicase binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in several processes, including hematopoietic stem cell differentiation; osteoblast differentiation; and positive regulation of stem cell differentiation. Predicted to localize to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 12. Orthologous to human SP7 (Sp7 transcription factor); INTERACTS WITH 5-formyltetrahydrofolic acid; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: osterix; Osx; Transcription factor Sp7
Orthologs:
Homo sapiens (human) : SP7 (Sp7 transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Sp7 (Sp7 transcription factor 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp7 (Sp7 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP7 (Sp7 transcription factor)
Canis lupus familiaris (dog) : SP7 (Sp7 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp7 (Sp7 transcription factor)
Sus scrofa (pig) : SP7 (Sp7 transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07143,957,316 - 143,967,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07141,753,826 - 141,762,790 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,109,771 - 141,118,397 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17141,186,207 - 141,194,213 (-)NCBI
Celera7129,919,226 - 129,927,844 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

Comparative Map Data
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QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
Protein Sequences
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Sp7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631377
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.