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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Zbed4 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1622984 | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of ZBED4 mRNA | CTD | PMID:22206623 | Zbed4 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1622984 | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZBED4 mRNA | CTD | PMID:22206623 | Zbed4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1314283 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZBED4 mRNA | CTD | PMID:22574217 | Zbed4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZBED4 mRNA | CTD | PMID:33387578 | Zbed4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1622984 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZBED4 mRNA | CTD | PMID:21570461 | Zbed4 | Rat | 2-methylcholine | affects expression | ISO | RGD:1314283 | 6480464 | beta-methylcholine affects the expression of ZBED4 mRNA | CTD | PMID:21179406 | Zbed4 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of ZBED4 mRNA | CTD | PMID:28522335 | Zbed4 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Zbed4 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ZBED4 mRNA | CTD | PMID:24780913 | Zbed4 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ZBED4 mRNA | CTD | PMID:30047161 | Zbed4 | Rat | aflatoxin B1 | increases expression | ISO | RGD:1314283 | 6480464 | Aflatoxin B1 results in increased expression of ZBED4 mRNA | CTD | PMID:22100608 | Zbed4 | Rat | aflatoxin B1 | increases methylation | ISO | RGD:1314283 | 6480464 | Aflatoxin B1 results in increased methylation of ZBED4 exon | CTD | PMID:30157460 | Zbed4 | Rat | all-trans-retinoic acid | decreases expression | ISO | RGD:1314283 | 6480464 | Tretinoin results in decreased expression of ZBED4 mRNA | CTD | PMID:33167477 | Zbed4 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ZBED4 mRNA | CTD | PMID:30047161 | Zbed4 | Rat | antirheumatic drug | increases expression | ISO | RGD:1314283 | 6480464 | Antirheumatic Agents results in increased expression of ZBED4 mRNA | CTD | PMID:24449571 | Zbed4 | Rat | atrazine | decreases expression | ISO | RGD:1314283 | 6480464 | Atrazine results in decreased expression of ZBED4 mRNA | CTD | PMID:22378314 | Zbed4 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | RGD:1314283 | 6480464 | Benzo(a)pyrene results in increased mutagenesis of ZBED4 gene | CTD | PMID:25435355 | Zbed4 | Rat | benzo[a]pyrene | affects methylation | ISO | RGD:1314283 | 6480464 | Benzo(a)pyrene affects the methylation of ZBED4 5' UTR; Benzo(a)pyrene affects the methylation of ZBED4 exon; more ... | CTD | PMID:27901495|PMID:30157460 | Zbed4 | Rat | benzo[a]pyrene | increases expression | ISO | RGD:1622984 | 6480464 | Benzo(a)pyrene results in increased expression of ZBED4 mRNA | CTD | PMID:22228805 | Zbed4 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1314283 | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZBED4 mRNA | CTD | PMID:20382639 | Zbed4 | Rat | benzo[e]pyrene | increases methylation | ISO | RGD:1314283 | 6480464 | benzo(e)pyrene results in increased methylation of ZBED4 exon | CTD | PMID:30157460 | Zbed4 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ZBED4 mRNA | CTD | PMID:25181051 | Zbed4 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Zbed4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ZBED4 mRNA | CTD | PMID:30816183|PMID:32528016|PMID:34947998 | Zbed4 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Zbed4 | Rat | cadmium dichloride | decreases expression | ISO | RGD:1314283 | 6480464 | Cadmium Chloride results in decreased expression of ZBED4 mRNA | CTD | PMID:38568856 | Zbed4 | Rat | caffeine | decreases phosphorylation | ISO | RGD:1314283 | 6480464 | Caffeine results in decreased phosphorylation of ZBED4 protein | CTD | PMID:35688186 | Zbed4 | Rat | cisplatin | decreases expression | ISO | RGD:1314283 | 6480464 | Cisplatin results in decreased expression of ZBED4 mRNA | CTD | PMID:27594783 | Zbed4 | Rat | cyclosporin A | increases expression | ISO | RGD:1314283 | 6480464 | Cyclosporine results in increased expression of ZBED4 mRNA | CTD | PMID:20106945 | Zbed4 | Rat | dicrotophos | increases expression | ISO | RGD:1314283 | 6480464 | dicrotophos results in increased expression of ZBED4 mRNA | CTD | PMID:28302478 | Zbed4 | Rat | doxorubicin | decreases expression | ISO | RGD:1314283 | 6480464 | Doxorubicin results in decreased expression of ZBED4 mRNA | CTD | PMID:29803840 | Zbed4 | Rat | epoxiconazole | decreases expression | ISO | RGD:1622984 | 6480464 | epoxiconazole results in decreased expression of ZBED4 mRNA | CTD | PMID:35436446 | Zbed4 | Rat | folic acid | multiple interactions | ISO | RGD:1622984 | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZBED4 mRNA | CTD | PMID:22206623 | Zbed4 | Rat | FR900359 | decreases phosphorylation | ISO | RGD:1314283 | 6480464 | FR900359 results in decreased phosphorylation of ZBED4 protein | CTD | PMID:37730182 | Zbed4 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ZBED4 mRNA | CTD | PMID:33387578 | Zbed4 | Rat | lead(0) | affects expression | ISO | RGD:1314283 | 6480464 | Lead affects the expression of ZBED4 mRNA | CTD | PMID:28903495 | Zbed4 | Rat | methapyrilene | increases methylation | ISO | RGD:1314283 | 6480464 | Methapyrilene results in increased methylation of ZBED4 exon | CTD | PMID:30157460 | Zbed4 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ZBED4 mRNA | CTD | PMID:30047161 | Zbed4 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZBED4 mRNA | CTD | PMID:25729387 | Zbed4 | Rat | p-toluidine | decreases expression | EXP | | 6480464 | 4-toluidine results in decreased expression of ZBED4 mRNA | CTD | PMID:27638505 | Zbed4 | Rat | paracetamol | affects expression | ISO | RGD:1622984 | 6480464 | Acetaminophen affects the expression of ZBED4 mRNA | CTD | PMID:17562736 | Zbed4 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ZBED4 mRNA | CTD | PMID:33387578 | Zbed4 | Rat | pirinixic acid | decreases expression | ISO | RGD:1622984 | 6480464 | pirinixic acid results in decreased expression of ZBED4 mRNA | CTD | PMID:23811191 | Zbed4 | Rat | rotenone | increases expression | ISO | RGD:1622984 | 6480464 | Rotenone results in increased expression of ZBED4 mRNA | CTD | PMID:32937126 | Zbed4 | Rat | sodium arsenite | increases expression | ISO | RGD:1314283 | 6480464 | sodium arsenite results in increased expression of ZBED4 mRNA | CTD | PMID:29301061 | Zbed4 | Rat | sodium arsenite | decreases expression | ISO | RGD:1314283 | 6480464 | sodium arsenite results in decreased expression of ZBED4 mRNA | CTD | PMID:38568856 | Zbed4 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of ZBED4 mRNA | CTD | PMID:30047161 | Zbed4 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ZBED4 mRNA | CTD | PMID:34492290 | Zbed4 | Rat | titanium dioxide | decreases methylation | ISO | RGD:1622984 | 6480464 | titanium dioxide results in decreased methylation of ZBED4 promoter | CTD | PMID:35295148 | Zbed4 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZBED4 mRNA | CTD | PMID:25729387 | Zbed4 | Rat | trimellitic anhydride | increases expression | ISO | RGD:1622984 | 6480464 | trimellitic anhydride results in increased expression of ZBED4 mRNA | CTD | PMID:19042947 | Zbed4 | Rat | triphenyl phosphate | affects expression | ISO | RGD:1314283 | 6480464 | triphenyl phosphate affects the expression of ZBED4 mRNA | CTD | PMID:37042841 | Zbed4 | Rat | urethane | increases expression | ISO | RGD:1314283 | 6480464 | Urethane results in increased expression of ZBED4 mRNA | CTD | PMID:28818685 | Zbed4 | Rat | valproic acid | increases methylation | ISO | RGD:1314283 | 6480464 | Valproic Acid results in increased methylation of ZBED4 gene | CTD | PMID:29154799 | Zbed4 | Rat | valproic acid | affects expression | ISO | RGD:1314283 | 6480464 | Valproic Acid affects the expression of ZBED4 mRNA | CTD | PMID:25979313 | Zbed4 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ZBED4 mRNA | CTD | PMID:23034163 | |