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Gene: Txn2 (thioredoxin 2) Rattus norvegicus
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Symbol: Txn2
Name: thioredoxin 2
Description: Contributes to peptide-methionine (R)-S-oxide reductase activity; peptide-methionine (S)-S-oxide reductase activity; and protein disulfide oxidoreductase activity. Involved in several processes, including response to axon injury; response to glucose; and response to hypoxia. Localizes to the dendrite; mitochondrion; and neuronal cell body. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human TXN2 (thioredoxin 2); INTERACTS WITH 1,1'-azobis(N,N-dimethylformamide); acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93312; mt-Trx; MTRX; thioredoxin mitochondrial; thioredoxin, mitochondrial; thioredoxin-2
Orthologs:
Homo sapiens (human) : TXN2 (thioredoxin 2)  HGNC  Alliance
Mus musculus (house mouse) : Txn2 (thioredoxin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txn2 (thioredoxin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TXN2 (thioredoxin 2)
Canis lupus familiaris (dog) : TXN2 (thioredoxin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txn2 (thioredoxin 2)
Sus scrofa (pig) : TXN2 (thioredoxin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07119,144,350 - 119,158,173 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07119,139,112 - 119,152,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47115,833,695 - 115,847,690 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17115,867,761 - 115,881,914 (-)NCBI
Celera7105,837,884 - 105,851,486 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Txn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71040
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-10-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.