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Gene: TXN2 (thioredoxin 2) Homo sapiens
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Symbol: TXN2
Name: thioredoxin 2
Description: Predicted to have peptide-methionine (R)-S-oxide reductase activity; peptide-methionine (S)-S-oxide reductase activity; and protein disulfide oxidoreductase activity. Predicted to be involved in sulfur amino acid catabolic process. Localizes to mitochondrion and nucleolus. Implicated in combined oxidative phosphorylation deficiency 29.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: COXPD29; mitochondrial thioredoxin; MT-TRX; MTRX; thioredoxin, mitochondrial; thioredoxin-2; TRX2; TXN
Orthologs:
Mus musculus (house mouse) : Txn2 (thioredoxin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Txn2 (thioredoxin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txn2 (thioredoxin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TXN2 (thioredoxin 2)
Canis lupus familiaris (dog) : TXN2 (thioredoxin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txn2 (thioredoxin 2)
Sus scrofa (pig) : TXN2 (thioredoxin 2)
Chlorocebus sabaeus (African green monkey) : TXN2 (thioredoxin 2)
Heterocephalus glaber (naked mole-rat) : Txn2 (thioredoxin 2)
more info ...
Related Pseudogenes: TXN2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2236,467,046 - 36,481,640 (-)EnsemblGRCh38hg38GRCh38
GRCh382236,467,036 - 36,481,672 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372236,863,083 - 36,878,072 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,193,039 - 35,207,633 (-)NCBINCBI36hg18NCBI36
Build 342235,187,592 - 35,202,187NCBI
Celera2220,665,238 - 20,679,833 (-)NCBI
Cytogenetic Map22q12.3NCBI
HuRef2219,831,327 - 19,845,504 (-)NCBIHuRef
CHM1_12236,822,047 - 36,836,640 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TXN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737462
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.