Tuba1b (tubulin, alpha 1B) - Rat Genome Database

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Gene: Tuba1b (tubulin, alpha 1B) Rattus norvegicus
Analyze
Symbol: Tuba1b (Ensembl: Tuba1a)
Name: tubulin, alpha 1B (Ensembl:tubulin, alpha 1A)
RGD ID: 1565476
Description: Predicted to enable several functions, including GTP binding activity; GTPase activity; and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within cellular response to interleukin-4. Located in membrane raft. Orthologous to human TUBA1B (tubulin alpha 1b); PARTICIPATES IN docetaxel pharmacodynamics pathway; tyrosinemia type III pathway; vinblastine pharmacodynamics pathway; INTERACTS WITH (S)-colchicine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Alpha-tubulin 1; alpha-tubulin 2; LOC500929; RGD1565476; similar to Tubulin alpha-2 chain (Alpha-tubulin 2); Tuba1; Tuba1a; Tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-1B chain; tubulin alpha-2 chain
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Tuba1b-ps1   Tuba1b-ps2  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87131,969,606 - 131,972,587 (-)NCBIGRCr8
mRatBN7.27130,090,663 - 130,093,644 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,081,032 - 130,196,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7131,895,962 - 131,898,943 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,121,536 - 134,124,517 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,034,040 - 134,037,021 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07140,614,746 - 140,617,721 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,614,752 - 140,617,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,121,815 - 115,124,065 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,706,858 - 137,709,839 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7126,575,851 - 126,578,847 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-colchicine  (EXP)
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
elemental selenium  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenbuconazole  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lovastatin  (ISO)
maneb  (ISO)
methamphetamine  (EXP)
miconazole  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-D-aspartic acid  (ISO)
Nivalenol  (ISO)
octadecanoic acid  (ISO)
ozone  (ISO)
paraquat  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
picoxystrobin  (ISO)
pinosylvin  (ISO)
raloxifene  (ISO)
rotenone  (EXP,ISO)
selenium atom  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
theophylline  (ISO)
thiram  (ISO)
trans-pinosylvin  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
vincaleukoblastine  (EXP)
vincristine  (EXP,ISO)
vitamin E  (ISO)
warfarin  (ISO)
zinc dichloride  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A revised nomenclature for the human and rodent alpha-tubulin gene family. Khodiyar VK, etal., Genomics. 2007 May 31;.
3. Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Ledesma MD, etal., Brain Res. 2003 Oct 10;987(1):107-16.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3753592   PMID:6269058   PMID:9798653   PMID:12477932   PMID:15489334   PMID:16418269   PMID:16854843   PMID:17634366   PMID:19103752   PMID:20131911   PMID:21266579   PMID:21525035  
PMID:21753002   PMID:23376485   PMID:31686426   PMID:32357304   PMID:34274903   PMID:35352799  


Genomics

Comparative Map Data
Tuba1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87131,969,606 - 131,972,587 (-)NCBIGRCr8
mRatBN7.27130,090,663 - 130,093,644 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,081,032 - 130,196,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7131,895,962 - 131,898,943 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,121,536 - 134,124,517 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,034,040 - 134,037,021 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07140,614,746 - 140,617,721 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,614,752 - 140,617,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,121,815 - 115,124,065 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,706,858 - 137,709,839 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7126,575,851 - 126,578,847 (-)NCBICelera
Cytogenetic Map7q36NCBI
TUBA1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,127,782 - 49,131,395 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,127,782 - 49,131,397 (-)EnsemblGRCh38hg38GRCh38
GRCh371249,521,565 - 49,525,178 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,807,832 - 47,811,571 (-)NCBINCBI36Build 36hg18NCBI36
Celera1248,315,719 - 48,319,458 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1246,552,484 - 46,556,221 (-)NCBIHuRef
CHM1_11249,487,375 - 49,491,114 (-)NCBICHM1_1
T2T-CHM13v2.01249,089,954 - 49,093,567 (-)NCBIT2T-CHM13v2.0
Tuba1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,829,310 - 98,832,271 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,829,306 - 98,832,446 (-)EnsemblGRCm39 Ensembl
GRCm381598,931,429 - 98,934,390 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,931,425 - 98,934,565 (-)EnsemblGRCm38mm10GRCm38
MGSCv371598,761,860 - 98,764,821 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361598,759,463 - 98,762,458 (-)NCBIMGSCv36mm8
Celera15101,080,871 - 101,083,832 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1555.21NCBI
LOC103782837
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21045,053,688 - 45,057,391 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11245,050,450 - 45,054,153 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01239,619,964 - 39,623,611 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11240,498,933 - 40,502,630 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,498,933 - 40,502,630 (+)Ensemblpanpan1.1panPan2
LOC106557476
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,407,906 - 5,412,265 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,407,906 - 5,463,809 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,844,807 - 40,849,166 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0275,459,258 - 5,463,625 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,459,258 - 5,515,230 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,423,976 - 5,428,332 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,413,310 - 5,417,672 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,237,770 - 41,242,127 (-)NCBIUU_Cfam_GSD_1.0
LOC101973055
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,234,375 - 66,238,196 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365126,926,820 - 6,930,307 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365126,926,634 - 6,930,481 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TUBA1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,149,099 - 15,153,620 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,150,229 - 15,153,620 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,556,615 - 15,560,002 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103238260
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,365,071 - 45,368,807 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1145,364,873 - 45,368,752 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037200,771,441 - 200,775,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tuba1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248163,047,272 - 3,050,777 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tuba1b
10 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
D5Arb10  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.17137,893,337 - 137,893,591RGD
Cytogenetic Map7q36UniSTS
PMC154451P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q36UniSTS
RH78682  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.04209,800,159 - 209,800,341UniSTSRnor5.0
Rnor_5.02218,687,079 - 218,687,261UniSTSRnor5.0
Cytogenetic Map7q36UniSTS
Cytogenetic Map9q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001044270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC076379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V01226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000081355   ⟹   ENSRNOP00000070868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,090,668 - 130,196,186 (-)Ensembl
Rnor_6.0 Ensembl7140,614,752 - 140,617,721 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083156   ⟹   ENSRNOP00000075232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,090,665 - 130,093,644 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107560   ⟹   ENSRNOP00000094561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,081,032 - 130,116,326 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110990   ⟹   ENSRNOP00000097331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,113,199 - 130,116,912 (-)Ensembl
RefSeq Acc Id: NM_001044270   ⟹   NP_001037735
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87131,969,606 - 131,972,587 (-)NCBI
mRatBN7.27130,090,663 - 130,093,644 (-)NCBI
Rnor_6.07140,614,746 - 140,617,721 (-)NCBI
RGSC_v3.47137,706,858 - 137,709,839 (-)RGD
Sequence:
RefSeq Acc Id: NP_001037735   ⟸   NM_001044270
- UniProtKB: Q6P9V9 (UniProtKB/Swiss-Prot),   A0A8I6ALV8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070868   ⟸   ENSRNOT00000081355
Ensembl Acc Id: ENSRNOP00000094561   ⟸   ENSRNOT00000107560
Ensembl Acc Id: ENSRNOP00000097331   ⟸   ENSRNOT00000110990
Ensembl Acc Id: ENSRNOP00000075232   ⟸   ENSRNOT00000083156
Protein Domains
Tubulin/FtsZ 2-layer sandwich   Tubulin/FtsZ GTPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P9V9-F1-model_v2 AlphaFold Q6P9V9 1-451 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695635
Promoter ID:EPDNEW_R6160
Type:multiple initiation site
Name:Tuba1b_1
Description:tubulin, alpha 1B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07140,617,719 - 140,617,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565476 AgrOrtholog
BioCyc Gene G2FUF-32103 BioCyc
Ensembl Genes ENSRNOG00000053468 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055029831 UniProtKB/Swiss-Prot
  ENSRNOG00060009018 UniProtKB/Swiss-Prot
  ENSRNOG00065020736 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000081355.2 UniProtKB/TrEMBL
  ENSRNOT00000083156.2 UniProtKB/TrEMBL
  ENSRNOT00000107560.1 UniProtKB/TrEMBL
  ENSRNOT00000110990.1 UniProtKB/TrEMBL
  ENSRNOT00055051685 UniProtKB/Swiss-Prot
  ENSRNOT00060015107 UniProtKB/Swiss-Prot
  ENSRNOT00065035161 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.600 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1330.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.1440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6920989 IMAGE-MGC_LOAD
  IMAGE:7106502 IMAGE-MGC_LOAD
InterPro Alpha_tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tub_FtsZ_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin/FtsZ-like_C UniProtKB/TrEMBL
  Tubulin/FtsZ_2-layer-sand-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin/FtsZ_C_sf UniProtKB/Swiss-Prot
  Tubulin/FtsZ_GTPase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_FtsZ_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:500929 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72839 IMAGE-MGC_LOAD
  MGC:93444 IMAGE-MGC_LOAD
NCBI Gene 500929 ENTREZGENE
PANTHER PTHR11588 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUBULIN ALPHA-1A CHAIN UniProtKB/TrEMBL
  TUBULIN ALPHA-1B CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tuba1b PhenoGen
PRINTS ALPHATUBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TUBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053468 RatGTEx
  ENSRNOG00055029831 RatGTEx
  ENSRNOG00060009018 RatGTEx
  ENSRNOG00065020736 RatGTEx
SMART Tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52490 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55307 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6ALV8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B5M1_RAT UniProtKB/TrEMBL
  A0A8L2R402_RAT UniProtKB/TrEMBL
  A0A8L2RAD9_RAT UniProtKB/TrEMBL
  Q6P9V9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2007-05-17 Tuba1b  tubulin, alpha 1B  RGD1565476_predicted  similar to Tubulin alpha-2 chain (Alpha-tubulin 2) (predicted)  Symbol and Name updated 1624988 APPROVED
2006-03-07 RGD1565476_predicted  similar to Tubulin alpha-2 chain (Alpha-tubulin 2) (predicted)  LOC500929  similar to Tubulin alpha-2 chain (Alpha-tubulin 2)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500929  similar to Tubulin alpha-2 chain (Alpha-tubulin 2)      Symbol and Name status set to provisional 70820 PROVISIONAL