Alg10 (ALG10, alpha-1,2-glucosyltransferase)

Gene: Alg10 (ALG10, alpha-1,2-glucosyltransferase) Rattus norvegicus

Analyze

Symbol:

Alg10

Name:

ALG10, alpha-1,2-glucosyltransferase

RGD ID:

708500

Description:

Predicted to enable dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity. Involved in potassium ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in long QT syndrome 2. Orthologous to several human genes including ALG10 (ALG10 alpha-1,2-glucosyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Alg10b; alpha-1,2-glucosyltransferase ALG10-A; alpha-2-glucosyltransferase ALG10-B; asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase); asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog; asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B; asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (S. pombe); asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast); asparagine-linked glycosylation protein 10 homolog B; KCR1; LOC245960; potassium channel regulator 1; putative alpha-1,2-glucosyltransferase ALG10-B; putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ALG10 (ALG10 alpha-1,2-glucosyltransferase)	HGNC	Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):	LOC102004837 (dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100971669 (dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Alg10 (ALG10 alpha-1,2-glucosyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	LOC101710247 (dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ALG10B (ALG10 alpha-1,2-glucosyltransferase B)	HGNC	EggNOG, Ensembl, Inparanoid, OrthoDB, Panther, PhylomeDB, Treefam
Alliance orthologs ³
Homo sapiens (human):	ALG10B (ALG10 alpha-1,2-glucosyltransferase B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ALG10 (ALG10 alpha-1,2-glucosyltransferase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Alg10b (ALG10 alpha-1,2-glucosyltransferase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	alg10 (ALG10 alpha-1,2-mannosyltransferase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Alg10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DIE2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tag-179	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	alg10	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	123,214,636 - 123,225,104 (+)	NCBI		GRCr8
mRatBN7.2	7	121,335,048 - 121,345,517 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	121,335,042 - 121,340,308 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	123,130,038 - 123,135,298 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	125,356,097 - 125,361,357 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	125,292,610 - 125,297,871 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	131,330,913 - 131,336,183 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	131,330,913 - 131,336,183 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	131,010,627 - 131,015,654 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	128,613,369 - 128,618,635 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	128,647,598 - 128,659,656 (+)	NCBI
Celera	7	117,794,570 - 117,799,842 (+)	NCBI		Celera
Cytogenetic Map	7	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

long QT syndrome 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3H-1,2-dithiole-3-thione (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

nickel atom (ISO)

perfluorooctanoic acid (EXP)

quercetin (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (EXP,ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

auditory receptor cell development (IEA)

dolichol-linked oligosaccharide biosynthetic process (IEA)

potassium ion transmembrane transport (IDA)

protein N-linked glycosylation (IBA)

sensory perception of sound (IEA)

Cellular Component

endoplasmic reticulum (IBA)

plasma membrane (IEA)

Molecular Function

dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity (IBA)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

N-linked glycan biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels.	Hoshi N, etal., J Biol Chem 1998 Sep 4;273(36):23080-5.
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:14525949	PMID:18231597	PMID:24303013

Genomics

Comparative Map Data

Alg10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	123,214,636 - 123,225,104 (+)	NCBI		GRCr8
mRatBN7.2	7	121,335,048 - 121,345,517 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	121,335,042 - 121,340,308 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	123,130,038 - 123,135,298 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	125,356,097 - 125,361,357 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	125,292,610 - 125,297,871 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	131,330,913 - 131,336,183 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	131,330,913 - 131,336,183 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	131,010,627 - 131,015,654 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	128,613,369 - 128,618,635 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	128,647,598 - 128,659,656 (+)	NCBI
Celera	7	117,794,570 - 117,799,842 (+)	NCBI		Celera
Cytogenetic Map	7	q35	NCBI

ALG10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	34,022,377 - 34,028,302 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	34,022,468 - 34,029,694 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	34,175,431 - 34,181,237 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	34,066,483 - 34,072,504 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	34,066,482 - 34,072,501	NCBI
Celera	12	13,983,778 - 13,989,799 (+)	NCBI		Celera
Cytogenetic Map	12	p11.1	NCBI
HuRef	12	33,915,997 - 33,922,020 (+)	NCBI		HuRef
CHM1_1	12	34,140,208 - 34,146,227 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	33,899,971 - 33,905,896 (+)	NCBI		T2T-CHM13v2.0

LOC102004837
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955505	1,844,005 - 1,854,229 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100971669
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	62,693,193 - 62,707,171 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	62,682,413 - 62,703,474 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	52,142,613 - 52,178,585 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	54,773,993 - 54,781,456 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	54,776,822 - 54,781,149 (-)	Ensembl	panpan1.1		panPan2

Alg10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	75,565,697 - 75,576,407 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936607	2,404,592 - 2,409,774 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC101710247
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624778	2,131,698 - 2,136,026 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624778	2,126,488 - 2,135,971 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Alg10
69 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	391
Count of miRNA genes:	231
Interacting mature miRNAs:	273
Transcripts:	ENSRNOT00000019672
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	84257275	129257275	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	84257275	129257275	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	86983365	131983365	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	91281130	135012528	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	91412594	129807172	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	96670164	135012528	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	102297359	133492884	Rat
731174	Uae23	Urinary albumin excretion QTL 23	2.4	0.0042	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	7	104603555	135012528	Rat
2306821	Bp335	Blood pressure QTL 335		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	106571501	135012528	Rat
631663	Bw6	Body weight QTL 6	3.4		body mass (VT:0001259)	body weight (CMO:0000012)	7	111075573	134976056	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	111182207	135012528	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	112308254	133492884	Rat
1357339	Stl14	Serum triglyceride level QTL 14	3.45	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	112729683	133492707	Rat
1582240	Sffal1	Serum free fatty acids level QTL 1	3.4	0.0021	blood free fatty acid amount (VT:0001553)	serum free fatty acids level (CMO:0000547)	7	116677010	124049952	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	116677189	127103496	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	119513385	135012528	Rat

Markers in Region

D7Wox49

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	7	131,336,217 - 131,336,315	NCBI	Rnor6.0
Cytogenetic Map	7	q34	UniSTS

BF398723

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	121,334,503 - 121,334,696 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	131,330,375 - 131,330,567	NCBI	Rnor6.0
Rnor_5.0	7	131,010,089 - 131,010,281	UniSTS	Rnor5.0
RGSC_v3.4	7	128,612,831 - 128,613,023	UniSTS	RGSC3.4
Celera	7	117,794,032 - 117,794,224	UniSTS
RH 3.4 Map	7	965.0	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH137265

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	121,345,127 - 121,345,311 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	131,341,241 - 131,341,424	NCBI	Rnor6.0
Rnor_5.0	7	131,020,698 - 131,020,881	UniSTS	Rnor5.0
RGSC_v3.4	7	128,625,038 - 128,625,221	UniSTS	RGSC3.4
Celera	7	117,804,614 - 117,804,797	UniSTS
RH 3.4 Map	7	964.9	UniSTS
Cytogenetic Map	7	q34	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		27	48	32	17	32	5	5	73	30	36	9	5
Low	3	16	9	9	2	9	3	6	1	5	5	2	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_139101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U78090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000019672 ⟹ ENSRNOP00000019672

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	121,335,042 - 121,340,308 (+)	Ensembl
Rnor_6.0 Ensembl	7	131,330,913 - 131,336,183 (+)	Ensembl

RefSeq Acc Id:

NM_139101 ⟹ NP_620801

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	123,214,636 - 123,225,104 (+)	NCBI
mRatBN7.2	7	121,335,048 - 121,345,517 (+)	NCBI
Rnor_6.0	7	131,330,913 - 131,336,183 (+)	NCBI
Rnor_5.0	7	131,010,627 - 131,015,654 (+)	NCBI
RGSC_v3.4	7	128,613,369 - 128,618,635 (+)	RGD
Celera	7	117,794,570 - 117,799,842 (+)	RGD

Sequence:

show sequence

CCCGCTGTACTTCACCAGGCAGTACTAGGCCATAGATCCCGTGTTCCGGGCTCGGCGCTCCGGG
CTTCCCAGGGCTGGGCCCGGGACGCGGCCTCCCGCCATGGCGCAGCTGGAGGGTTATTACTTCT
CGGCCGCCTTGAGCTGCACCTTCCTGGTGTCCTGCCTGCTCTTCTCCGCCTTCAGCCGCGCTCT
GCGTGAGCCTTACATGGACGAGATCTTCCACCTGCCGCAGGCGCAGCGCTACTGCGAGGGCCGC
TTCTCACTGTCACAGTGGGATCCTATGATTACTACATTACCTGGCCTGTACCTGGTGTCGGTCG
GAGTGGTCAAACCTGCCAGCTGGATCCTTGGCTGGTCTGAGCATGTCGTCTGCTCCATCGGAAT
GCTCAGATTTGTCAATCTTCTCTTCAGTGTTGGCAACTTCTATTTGCTGTATTTGCTCTTCAGG
AAGATACAGCCCAGAAACAAGGCTTCTTCAAGTATCCAGAGAATCTTGTCAACATTAACCCTAG
CAGTATTTCCAACCCTCTATTTTTTTAACTTTCTTTACTATACAGAAGCCGGCTCTGTATTCTT
TACTCTTTTTGCTTATTTGATGTGTCTTTACGGCAACCATAGGACTTCGGCCTTGCTTGGGTTT
TGTGGCTTCATGTTTCGTCAGACCAATATCATCTGGGCTGCCTTCTGTGCAGGACACATCATTG
CACAGAAGTGCAGTGAAGCCTGGAAGACTGAACTACAGAAGAAGAAGGAAGAGAGGCTTCCCCC
GGCTAAAGGACCGCTCTCGGAACTCAGAAGAGTTCTTCAGTTTCTGCTGATGTACTCCATGTCC
CTTAAGAACCTGAGTATGCTTTTCCTTTTGACCTGGCCCTACATGCTTCTGCTGTTGGCATTTT
TCGTTTTTGTGGTGGTTAATGGTGGGATTGTCGTGGGTGATCGGAGTAGTCATGAGGCCTGCCT
CCATTTTCCTCAGTTGTTCTACTTCTTCTCCTTTACTGCCTTTTTTTCCTTTCCTCACCTACTT
TCTCCGACCAAAGTCAAGACTTTTCTTAGCTTAGTTTGGAAACGTAGAGTTCAGTTCTCTGTGA
TTACTTTAGTCTCGGTATTTTTGGTTTGGAAATTCACTTACGTCCATAAGTATTTACTGGCAGA
CAATAGGCATTACACGTTTTATGTGTGGAAAAGAGTATTTCAGAGACATGAAATTGTCAAGTAT
TTATTAGTTCCAGCCTACATGTTTGCTGGTTGGGCTGTAGCTGACTCTTTAAAATCAAAGTCAA
TTTTCTGGAATTTAATGTTTTTTGTATGCTTGGTTGCTTCTACGGTTCCTCAGAAACTACTAGA
ATTCCGTTACTTCATTTTACCATACATTATTTATAGGCTCAACATGCCTCTGCCACCCATATCT
AGACTTGTTTGTGAACTGGGTTGCTATGCAGTTGTCAATTTTCTAACTTTTTACATCTTTCTGA
ACAAGACTTTTCAGTGGTCGGATAGTCATGACATCCAAAGGTTTATGTGGTAGTGGCAGGGCTA
TTTTGAACTCTAAGAGCCTATTTCTACAACAGATGACTGGGTAAAGGAGTGTGGATTTCTTTTA
AGTAAATTCAGGGAGACGAAAAGAATTACATTTGAGGCTAGCCTAAAAGCTTAGATAATGCTAA
TAAATTTGCTTGCAGTTGTCTTGAGAATCTTTTCAGAAGTTTGGGGATTTTCCGTGTATGTAGG
GGACTGGGTGAGCTCCGTAGCACCAGAACCTGTCAACCAACTTCCTTTGTAAAGAACAGTGAAG
AATGTGAAAACTGTTTACAAATAAATGACCTAGTGGTATTTCTGAGCAAAATTGCCAGATATTG
CAGTAAATATAGCTCTGGTCTTAGTAACTTATGAACGAGATTCTGGGATGTCTATCTAGGAATT
GGGTATTTTAACTAAGAATATAGAAGTGATGAAGCCATTTGAACTAACTCCTTATTTGAAGGTT
TTGCAGGCCGAAGGTAAGCTGTGCTGATTATGACACCTTTTATAGATAATCTTTCTGAAATACT
GCTCTGTTAGTTGTCCAGGGCTCCTGCACAAAACTGACCATAAACCTTGTGGCTTCAGAGTTTT
TTCTCACATACGAATAAGCAGCACCTAAACTCGAGTGCTGGCAGAGCTCCTAAACTCGAGTGCT
GGCAGAGCTCGCTCCTTCAGGAGACAAGAGTTCATTGTTCCTGTTCAGCTCACTCCTTAGAGGG
GCCTTACTTTTAGACAGGTCCCTCCAGTCTGTCTGTGTCTGCACAGGACTGTCTCCACCGGCTT
CTTGTGCAGTTAATGCCATTGGCTTTAGGGATCCTCTGATTCAGGGTAACGGTACCTGGAGACC
CT

hide sequence

Protein Sequences


Protein RefSeqs	NP_620801	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC34249	(Get FASTA)	NCBI Sequence Viewer
	EDL76589	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019672
	ENSRNOP00000019672.2
	ENSRNOP00055016732
	ENSRNOP00060008215
GenBank Protein	O88788	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_620801 ⟸ NM_139101

- UniProtKB:

O88788 (UniProtKB/Swiss-Prot), A6K7P5 (UniProtKB/TrEMBL), A6K7P6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQLEGYYFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGRFSLSQWDPMITT
LPGLYLVSVGVVKPASWILGWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFRKIQPRNKASSSI
QRILSTLTLAVFPTLYFFNFLYYTEAGSVFFTLFAYLMCLYGNHRTSALLGFCGFMFRQTNIIW
AAFCAGHIIAQKCSEAWKTELQKKKEERLPPAKGPLSELRRVLQFLLMYSMSLKNLSMLFLLTW
PYMLLLLAFFVFVVVNGGIVVGDRSSHEACLHFPQLFYFFSFTAFFSFPHLLSPTKVKTFLSLV
WKRRVQFSVITLVSVFLVWKFTYVHKYLLADNRHYTFYVWKRVFQRHEIVKYLLVPAYMFAGWA
VADSLKSKSIFWNLMFFVCLVASTVPQKLLEFRYFILPYIIYRLNMPLPPISRLVCELGCYAVV
NFLTFYIFLNKTFQWSDSHDIQRFMW

hide sequence

RefSeq Acc Id:

ENSRNOP00000019672 ⟸ ENSRNOT00000019672

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O88788-F1-model_v2	AlphaFold	O88788	1-474	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695595

Promoter ID:

EPDNEW_R6119

Type:

initiation region

Name:

Alg10_1

Description:

ALG10, alpha-1,2-glucosyltransferase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	131,330,919 - 131,330,979	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708500	AgrOrtholog
BioCyc Gene	G2FUF-32414	BioCyc
BioCyc Pathway	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS [protein N-glycosylation initial phase (eukaryotic)]	BioCyc
BioCyc Pathway Image	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS	BioCyc
Ensembl Genes	ENSRNOG00000014511	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055012199	UniProtKB/Swiss-Prot
	ENSRNOG00060006725	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000019672	ENTREZGENE
	ENSRNOT00000019672.6	UniProtKB/Swiss-Prot
	ENSRNOT00055020746	UniProtKB/Swiss-Prot
	ENSRNOT00060011015	UniProtKB/Swiss-Prot
InterPro	Alg10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:245960	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	245960	ENTREZGENE
PANTHER	ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10	UniProtKB/TrEMBL
	DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR12989	UniProtKB/Swiss-Prot
Pfam	DIE2_ALG10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Alg10	PhenoGen
PIRSF	Alpha1_2_glucosyltferase_Alg10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014511	RatGTEx
	ENSRNOG00055012199	RatGTEx
	ENSRNOG00060006725	RatGTEx
UniProt	A6K7P5	ENTREZGENE, UniProtKB/TrEMBL
	A6K7P6	ENTREZGENE, UniProtKB/TrEMBL
	AG10B_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-03-20	Alg10	ALG10, alpha-1,2-glucosyltransferase	Alg10	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-20	Alg10	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe)	Alg10b	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (S. pombe)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-20	Alg10b	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (S. pombe)	Alg10b	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-02-04	Alg10b	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)	Alg10b	asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-25	Alg10b	asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase)	LOC245960	potassium channel regulator 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-09-30	LOC245960				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways