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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pmm1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PMM1 mRNA | CTD | PMID:36331819 | Pmm1 | Rat | 1,2-dichloroethane | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of PMM1 mRNA | CTD | PMID:28960355 | Pmm1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PMM1 mRNA | CTD | PMID:22206623 | Pmm1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PMM1 mRNA] | CTD | PMID:22206623 | Pmm1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of PMM1 mRNA | CTD | PMID:17942748 | Pmm1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PMM1 mRNA | CTD | PMID:17942748 | Pmm1 | Rat | 17beta-estradiol | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of PMM1 mRNA | CTD | PMID:31614463 | Pmm1 | Rat | 1H-pyrazole | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | pyrazole results in increased expression of PMM1 mRNA | CTD | PMID:17945193 | Pmm1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of PMM1 mRNA more ... | CTD | PMID:16214954 more ... | Pmm1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PMM1 mRNA | CTD | PMID:18796159 more ... | Pmm1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PMM1 mRNA | CTD | PMID:18691609 more ... | Pmm1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pmm1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PMM1 mRNA | CTD | PMID:20702594 more ... | Pmm1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | PMM1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PMM1 mRNA | CTD | PMID:22298810 | Pmm1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PMM1 mRNA | CTD | PMID:22298810 and PMID:34747641 | Pmm1 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | ISO | Pmm1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:20702594 | Pmm1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of PMM1 mRNA | CTD | PMID:21346803 | Pmm1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of PMM1 mRNA | CTD | PMID:21346803 | Pmm1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PMM1 mRNA | CTD | PMID:30851411 | Pmm1 | Rat | 2-nitrofluorene | increases expression | EXP | | 6480464 | 2-nitrofluorene results in increased expression of PMM1 mRNA | CTD | PMID:22484513 | Pmm1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | affects expression | ISO | Pmm1 (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:20702594 | Pmm1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:32119087 | Pmm1 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | PMM1 (Homo sapiens) | 6480464 | Decitabine affects the expression of PMM1 mRNA | CTD | PMID:23300844 | Pmm1 | Rat | aflatoxin B1 | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PMM1 mRNA | CTD | PMID:19770486 | Pmm1 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of PMM1 mRNA | CTD | PMID:22484513 | Pmm1 | Rat | all-trans-retinoic acid | decreases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Tretinoin results in decreased expression of PMM1 mRNA | CTD | PMID:16604517 | Pmm1 | Rat | amiodarone | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Amiodarone results in increased expression of PMM1 mRNA | CTD | PMID:24489787 | Pmm1 | Rat | aristolochic acid A | increases expression | ISO | PMM1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PMM1 mRNA | CTD | PMID:33212167 | Pmm1 | Rat | arsenous acid | decreases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of PMM1 mRNA | CTD | PMID:35676786 | Pmm1 | Rat | benzo[a]pyrene | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of PMM1 mRNA] and Benzo(a)pyrene promotes the reaction [AHR protein binds to PMM1 promoter] | CTD | PMID:15034205 and PMID:19654925 | Pmm1 | Rat | benzo[a]pyrene | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PMM1 mRNA | CTD | PMID:15034205 more ... | Pmm1 | Rat | Benzo[k]fluoranthene | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in increased expression of PMM1 mRNA | CTD | PMID:26377693 | Pmm1 | Rat | bisphenol A | decreases expression | ISO | Pmm1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PMM1 mRNA | CTD | PMID:26063408 and PMID:35598803 | Pmm1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PMM1 mRNA | CTD | PMID:25181051 | Pmm1 | Rat | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of PMM1 protein | CTD | PMID:28903499 | Pmm1 | Rat | cadmium atom | multiple interactions | ISO | PMM1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PMM1 mRNA | CTD | PMID:35301059 | Pmm1 | Rat | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of PMM1 mRNA | CTD | PMID:22110744 | Pmm1 | Rat | cadmium dichloride | multiple interactions | ISO | PMM1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PMM1 mRNA | CTD | PMID:35301059 | Pmm1 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of PMM1 mRNA | CTD | PMID:33453195 | Pmm1 | Rat | caffeine | increases phosphorylation | ISO | PMM1 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of PMM1 protein | CTD | PMID:35688186 | Pmm1 | Rat | ciglitazone | multiple interactions | ISO | PMM1 (Homo sapiens) | 6480464 | [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PMM1 mRNA | CTD | PMID:16197558 | Pmm1 | Rat | cisplatin | increases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of PMM1 mRNA | CTD | PMID:27594783 | Pmm1 | Rat | cisplatin | affects expression | ISO | PMM1 (Homo sapiens) | 6480464 | Cisplatin affects the expression of PMM1 mRNA | CTD | PMID:23300844 | Pmm1 | Rat | clofibrate | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Clofibrate results in increased expression of PMM1 mRNA | CTD | PMID:23811191 | Pmm1 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PMM1 mRNA | CTD | PMID:24386269 | Pmm1 | Rat | copper(II) sulfate | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PMM1 mRNA | CTD | PMID:19549813 | Pmm1 | Rat | cyclosporin A | increases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PMM1 mRNA | CTD | PMID:20106945 | Pmm1 | Rat | cyclosporin A | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PMM1 mRNA | CTD | PMID:27989131 | Pmm1 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of PMM1 mRNA | CTD | PMID:23640034 | Pmm1 | Rat | diarsenic trioxide | decreases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of PMM1 mRNA | CTD | PMID:35676786 | Pmm1 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of PMM1 mRNA | CTD | PMID:21266533 | Pmm1 | Rat | dichloroacetic acid | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of PMM1 mRNA | CTD | PMID:28962523 | Pmm1 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of PMM1 mRNA | CTD | PMID:37077353 | Pmm1 | Rat | dioxygen | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PMM1 mRNA | CTD | PMID:30529165 | Pmm1 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of PMM1 mRNA | CTD | PMID:24136188 | Pmm1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of PMM1 mRNA | CTD | PMID:24136188 | Pmm1 | Rat | folic acid | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PMM1 mRNA] | CTD | PMID:22206623 | Pmm1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PMM1 mRNA | CTD | PMID:33387578 | Pmm1 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of PMM1 mRNA | CTD | PMID:21396975 | Pmm1 | Rat | inulin | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PMM1 mRNA | CTD | PMID:36331819 | Pmm1 | Rat | ketoconazole | increases expression | EXP | | 6480464 | Ketoconazole results in increased expression of PMM1 mRNA | CTD | PMID:37077353 | Pmm1 | Rat | leflunomide | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of PMM1 mRNA | CTD | PMID:28988120 | Pmm1 | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of PMM1 mRNA | CTD | PMID:24136188 | Pmm1 | Rat | methyl methanesulfonate | increases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PMM1 mRNA | CTD | PMID:23649840 | Pmm1 | Rat | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of PMM1 mRNA | CTD | PMID:19638242 | Pmm1 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of PMM1 mRNA | CTD | PMID:28943392 | Pmm1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of PMM1 mRNA | CTD | PMID:25729387 | Pmm1 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of PMM1 mRNA | CTD | PMID:25729387 | Pmm1 | Rat | paracetamol | affects expression | ISO | Pmm1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PMM1 mRNA | CTD | PMID:17562736 | Pmm1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PMM1 mRNA | CTD | PMID:33387578 | Pmm1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PMM1 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PMM1 mRNA | CTD | PMID:36331819 | Pmm1 | Rat | pirinixic acid | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of PMM1 mRNA and PPARA protein promotes the reaction [pirinixic acid results in increased expression of PMM1 mRNA] | CTD | PMID:20059764 and PMID:20813756 | Pmm1 | Rat | pirinixic acid | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PMM1 mRNA | CTD | PMID:17426115 more ... | Pmm1 | Rat | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of PMM1 mRNA | CTD | PMID:22484513 | Pmm1 | Rat | rac-lactic acid | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PMM1 mRNA | CTD | PMID:30851411 | Pmm1 | Rat | rimonabant | multiple interactions | ISO | Pmm1 (Mus musculus) | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PMM1 mRNA] | CTD | PMID:19030233 | Pmm1 | Rat | silicon dioxide | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of PMM1 mRNA | CTD | PMID:25895662 | Pmm1 | Rat | sodium arsenite | increases expression | ISO | PMM1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PMM1 mRNA | CTD | PMID:38568856 | Pmm1 | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of PMM1 mRNA | CTD | PMID:25993096 | Pmm1 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of PMM1 mRNA | CTD | PMID:19281266 | Pmm1 | Rat | temozolomide | decreases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of PMM1 mRNA | CTD | PMID:31758290 | Pmm1 | Rat | tetrachloromethane | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PMM1 mRNA | CTD | PMID:27339419 and PMID:31919559 | Pmm1 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PMM1 mRNA | CTD | PMID:31150632 | Pmm1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PMM1 mRNA | CTD | PMID:23411599 and PMID:34492290 | Pmm1 | Rat | thioacetamide | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of PMM1 mRNA | CTD | PMID:28943392 | Pmm1 | Rat | titanium dioxide | decreases expression | ISO | Pmm1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PMM1 mRNA | CTD | PMID:23557971 | Pmm1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of PMM1 mRNA | CTD | PMID:25729387 | Pmm1 | Rat | trichloroethene | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of PMM1 mRNA | CTD | PMID:25549359 | Pmm1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PMM1 mRNA | CTD | PMID:33387578 | Pmm1 | Rat | trimellitic anhydride | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of PMM1 mRNA | CTD | PMID:19042947 | Pmm1 | Rat | triphenyl phosphate | affects expression | ISO | PMM1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PMM1 mRNA | CTD | PMID:37042841 | Pmm1 | Rat | triptonide | decreases expression | ISO | Pmm1 (Mus musculus) | 6480464 | triptonide results in decreased expression of PMM1 mRNA | CTD | PMID:33045310 | Pmm1 | Rat | tungsten | increases expression | ISO | Pmm1 (Mus musculus) | 6480464 | Tungsten results in increased expression of PMM1 mRNA | CTD | PMID:30912803 | Pmm1 | Rat | tunicamycin | increases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of PMM1 mRNA | CTD | PMID:22378314 | Pmm1 | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of PMM1 mRNA | CTD | PMID:24136188 | Pmm1 | Rat | valproic acid | increases expression | ISO | PMM1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PMM1 mRNA | CTD | PMID:23179753 and PMID:29154799 | Pmm1 | Rat | valproic acid | affects expression | ISO | PMM1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PMM1 mRNA | CTD | PMID:25979313 | |