PMM1 (phosphomannomutase 1) - Rat Genome Database

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Gene: PMM1 (phosphomannomutase 1) Canis lupus familiaris
Analyze
Symbol: PMM1
Name: phosphomannomutase 1
RGD ID: 12229093
Description: ENCODES a protein that exhibits isomerase activity (inferred); metal ion binding (inferred); phosphomannomutase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); common variable immunodeficiency 4 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); neuronal cell body (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,699,476 - 23,706,716 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,700,387 - 23,706,547 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,629,920 - 23,639,439 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,442,035 - 24,451,570 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,442,045 - 24,451,565 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,158,621 - 24,168,390 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,480,091 - 24,489,609 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,654,164 - 24,663,696 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PMM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,699,476 - 23,706,716 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,700,387 - 23,706,547 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,629,920 - 23,639,439 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,442,035 - 24,451,570 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,442,045 - 24,451,565 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,158,621 - 24,168,390 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,480,091 - 24,489,609 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,654,164 - 24,663,696 (+)NCBIUU_Cfam_GSD_1.0
PMM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,576,900 - 41,589,840 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,576,900 - 41,589,871 (-)EnsemblGRCh38hg38GRCh38
GRCh372241,972,904 - 41,985,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,302,858 - 40,315,759 (-)NCBINCBI36Build 36hg18NCBI36
Build 342240,297,411 - 40,310,313NCBI
Celera2225,779,317 - 25,792,298 (-)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2224,938,706 - 24,951,582 (-)NCBIHuRef
CHM1_12241,933,029 - 41,946,009 (-)NCBICHM1_1
T2T-CHM13v2.02242,055,771 - 42,068,712 (-)NCBIT2T-CHM13v2.0
Pmm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,835,307 - 81,845,131 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,835,309 - 81,845,131 (-)EnsemblGRCm39 Ensembl
GRCm381581,951,106 - 81,960,930 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,951,108 - 81,960,930 (-)EnsemblGRCm38mm10GRCm38
MGSCv371581,781,536 - 81,791,297 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,778,367 - 81,788,119 (-)NCBIMGSCv36mm8
Celera1584,073,154 - 84,082,920 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.3NCBI
Pmm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,346,767 - 115,357,137 (-)NCBIGRCr8
mRatBN7.27113,466,632 - 113,477,004 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,466,632 - 113,477,022 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,229,302 - 115,239,546 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,452,796 - 117,463,040 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,422,239 - 117,432,483 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,183,504 - 123,193,874 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,183,506 - 123,193,761 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,158,885 - 123,169,142 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,323,808 - 120,334,065 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17120,358,039 - 120,368,295 (-)NCBI
Celera7109,782,496 - 109,792,754 (-)NCBICelera
Cytogenetic Map7q34NCBI
Pmm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541327,090,291 - 27,097,088 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541327,090,291 - 27,097,088 (-)NCBIChiLan1.0ChiLan1.0
PMM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22351,408,349 - 51,422,735 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12254,107,618 - 54,120,592 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02222,472,067 - 22,485,029 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12240,558,733 - 40,571,811 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,558,733 - 40,571,811 (-)Ensemblpanpan1.1panPan2
Pmm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,347,295 - 7,357,622 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936492357,665 - 372,008 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936492357,732 - 368,042 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PMM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl56,964,999 - 6,975,904 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.156,964,999 - 6,975,904 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,336,774 - 4,347,697 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PMM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,115,717 - 24,128,869 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1924,118,481 - 24,128,830 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045101,285,073 - 101,296,826 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pmm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,039,789 - 7,047,069 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247527,039,781 - 7,047,069 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PMM1
65 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000001607   ⟹   ENSCAFP00000001479
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1023,700,387 - 23,706,547 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845029470   ⟹   ENSCAFP00845023152
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1024,442,045 - 24,451,565 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845029533   ⟹   ENSCAFP00845023198
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1024,442,045 - 24,451,565 (+)Ensembl
RefSeq Acc Id: XM_038488493   ⟹   XP_038344421
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11024,158,621 - 24,168,390 (+)NCBI
RefSeq Acc Id: XM_038550419   ⟹   XP_038406347
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01024,654,164 - 24,663,696 (+)NCBI
RefSeq Acc Id: XM_038614385   ⟹   XP_038470313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01024,480,091 - 24,489,609 (+)NCBI
RefSeq Acc Id: XM_038638277   ⟹   XP_038494205
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1023,629,920 - 23,639,439 (+)NCBI
RefSeq Acc Id: XM_038679728   ⟹   XP_038535656
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01024,442,035 - 24,451,570 (+)NCBI
Ensembl Acc Id: ENSCAFP00000001479   ⟸   ENSCAFT00000001607
RefSeq Acc Id: XP_038344421   ⟸   XM_038488493
RefSeq Acc Id: XP_038470313   ⟸   XM_038614385
RefSeq Acc Id: XP_038535656   ⟸   XM_038679728
- UniProtKB: A0A8C0PF48 (UniProtKB/TrEMBL),   A0A8C0JMF0 (UniProtKB/TrEMBL),   A0A8I3P0K5 (UniProtKB/TrEMBL),   A0A8C0SVI4 (UniProtKB/TrEMBL),   A0A8I3P5G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038494205   ⟸   XM_038638277
- UniProtKB: A0A8C0PF48 (UniProtKB/TrEMBL),   A0A8C0JMF0 (UniProtKB/TrEMBL),   A0A8I3P0K5 (UniProtKB/TrEMBL),   A0A8C0SVI4 (UniProtKB/TrEMBL),   A0A8I3P5G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406347   ⟸   XM_038550419
- UniProtKB: A0A8C0JMF0 (UniProtKB/TrEMBL),   A0A8C0PF48 (UniProtKB/TrEMBL),   A0A8C0SVI4 (UniProtKB/TrEMBL),   A0A8I3P0K5 (UniProtKB/TrEMBL),   A0A8I3P5G2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845023198   ⟸   ENSCAFT00845029533
Ensembl Acc Id: ENSCAFP00845023152   ⟸   ENSCAFT00845029470


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001049 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030023255 UniProtKB/TrEMBL
  ENSCAFG00040017131 UniProtKB/TrEMBL
  ENSCAFG00845016625 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000001607.6 UniProtKB/TrEMBL
  ENSCAFT00030042746.1 UniProtKB/TrEMBL
  ENSCAFT00030042789.1 UniProtKB/TrEMBL
  ENSCAFT00040031648.1 UniProtKB/TrEMBL
  ENSCAFT00040031730.1 UniProtKB/TrEMBL
  ENSCAFT00845029470.1 UniProtKB/TrEMBL
  ENSCAFT00845029533 ENTREZGENE
  ENSCAFT00845029533.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1240.20 UniProtKB/TrEMBL
  3.40.50.1000 UniProtKB/TrEMBL
InterPro HAD-like_sf UniProtKB/TrEMBL
  HAD-SF_hydro_IIB UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  PMM UniProtKB/TrEMBL
  PMM_cap UniProtKB/TrEMBL
NCBI Gene PMM1 ENTREZGENE
PANTHER PHOSPHOMANNOMUTASE 1 UniProtKB/TrEMBL
  PTHR10466 UniProtKB/TrEMBL
Pfam PMM UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/TrEMBL
UniProt A0A8C0JMF0 ENTREZGENE
  A0A8C0PF48 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SVI4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P0K5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P5G2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44733 ENTREZGENE