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Gene: Arsa (arylsulfatase A) Rattus norvegicus
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Symbol: Arsa
Name: arylsulfatase A
Description: Exhibits arylsulfatase activity. Involved in several processes, including response to estrogen; response to ethanol; and response to methylmercury. Localizes to several cellular components, including the cytoplasmic vesicle; extrinsic component of external side of plasma membrane; and lysosome. Used to study hypothyroidism. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human ARSA (arylsulfatase A); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC315222; MGC125207
Orthologs:
Homo sapiens (human) : ARSA (arylsulfatase A)  HGNC  Alliance
Mus musculus (house mouse) : Arsa (arylsulfatase A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arsa (arylsulfatase A)
Pan paniscus (bonobo/pygmy chimpanzee) : ARSA (arylsulfatase A)
Canis lupus familiaris (dog) : ARSA (arylsulfatase A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arsa (arylsulfatase A)
Sus scrofa (pig) : ARSA (arylsulfatase A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07130,446,644 - 130,452,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,446,668 - 130,451,283 (-)Ensembl
Rnor_5.07130,131,465 - 130,137,453 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,790,208 - 127,792,734 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17127,824,434 - 127,826,966 (-)NCBI
Celera7117,017,039 - 117,019,565 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Arsa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310381
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.