Exhibits several functions, including anion binding activity; chaperone binding activity; and identical protein binding activity. Involved in several processes, including response to lipopolysaccharide; thyroid hormone generation; and transcytosis. Localizes to several cellular components, including Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Used to study hypothyroidism and isolated growth hormone deficiency. Human ortholog(s) of this gene implicated in Graves' disease; autoimmune thyroiditis; and goiter. Orthologous to human TG (thyroglobulin); PARTICIPATES IN thyroid hormone biosynthetic pathway; autoimmune thyroiditis pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
[Clofibrate co-treated with Acetaminophen] affects the expression of TG mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TG mRNA]
[Clofibrate co-treated with Acetaminophen] affects the expression of TG mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TG mRNA]
BRAF protein mutant form affects the reaction [vorinostat affects the reaction [[TSHB protein co-treated with vemurafenib] affects the expression of TG mRNA]] more ...
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
The genomic region containing this gene has been resequenced in the Fisher 344 rat cell line PCCl3 by Dr. Daniel Christophe's group at Universite Libre de Bruxelles. The unknown sequence between genomic positions 104042649 and 104042698 has now been determined to be aaagatttgagTTAAAATTCTCTTTATCAGCCTTTATCATTAATTACTATGTTTGtcttgtcttctt
Gene-Chemical Interaction Annotations
