Sstr3 (somatostatin receptor 3) - Rat Genome Database

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Gene: Sstr3 (somatostatin receptor 3) Rattus norvegicus
Analyze
Symbol: Sstr3
Name: somatostatin receptor 3
RGD ID: 620308
Description: Predicted to enable G protein-coupled receptor activity; neuropeptide binding activity; and signaling receptor binding activity. Involved in several processes, including brain development; cellular response to estradiol stimulus; and cellular response to glucocorticoid stimulus. Predicted to be located in ciliary membrane and non-motile cilium. Predicted to be active in neuron projection and plasma membrane. Orthologous to human SSTR3 (somatostatin receptor 3); INTERACTS WITH (+)-pilocarpine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Smstr28; somatostatin receptor 28; somatostatin receptor subtype 3; somatostatin receptor type 3; SS-3-R; SS3-R; SS3R; SSR-28; SSTR
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,973,049 - 111,980,250 (-)NCBIGRCr8
mRatBN7.27110,092,563 - 110,109,043 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,092,575 - 110,099,769 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,843,786 - 111,850,977 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,067,323 - 114,074,514 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,035,025 - 114,042,224 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,760,881 - 119,768,082 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,760,888 - 119,768,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,749,191 - 119,756,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,495,750 - 116,502,948 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,529,980 - 116,537,178 (-)NCBI
Celera7106,430,574 - 106,437,768 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
Ampullosporin  (EXP)
aristolochic acid A  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
corn oil  (EXP)
Cuprizon  (EXP)
D-gluconic acid  (EXP)
D-glucose  (EXP)
deoxycholic acid  (EXP)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
dichlorine  (EXP)
dieldrin  (EXP)
disodium selenite  (ISO)
endosulfan  (EXP)
ethylparaben  (ISO)
fentin chloride  (EXP)
flunitrazepam  (EXP)
formaldehyde  (EXP)
glucose  (EXP)
ketamine  (EXP)
lanreotide  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (EXP)
oxybenzone  (EXP)
ozone  (EXP)
paracetamol  (EXP)
pasireotide  (ISO)
PCB138  (ISO)
Soman  (EXP)
somatostatin  (ISO)
Tesaglitazar  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (EXP)
triclosan  (ISO)
troglitazone  (EXP)
vinclozolin  (EXP)
zolpidem  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Identification of multiple somatostatin receptors in the rat somatosensory cortex during development. Bologna E and Leroux P, J Comp Neurol. 2000 May 15;420(4):466-80.
2. Expression changes of somatostatin receptor subtypes sst2A, sst2B, sst3 and sst4 after a cortical contusion trauma in rats. Braun H, etal., Brain Res. 2002 Mar 15;930(1-2):191-9.
3. Pituitary and hypothalamic somatostatin receptor subtype messenger ribonucleic acid expression in the food-deprived and diabetic rat. Bruno JF, etal., Endocrinology. 1994 Nov;135(5):1787-92.
4. Effect of 17beta-estradiol on somatostatin receptor expression and inhibitory effects on growth hormone and prolactin release in rat pituitary cell cultures. Djordjijevic D, etal., Endocrinology. 1998 May;139(5):2272-7.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy. Kumar U, etal., Endocrinology. 1997 Oct;138(10):4473-6.
8. Molecular cloning of a somatostatin-28 receptor and comparison of its expression pattern with that of a somatostatin-14 receptor in rat brain. Meyerhof W, etal., Proc Natl Acad Sci U S A 1992 Nov 1;89(21):10267-71.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. Role of glucocorticoids in the regulation of pituitary somatostatin receptor subtype (sst1-sst5) mRNA levels: evidence for direct and somatostatin-mediated effects. Park S, etal., Neuroendocrinology. 2003 Sep;78(3):163-75.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Differential expression of multiple somatostatin receptors in the rat cerebellum during development. Viollet C, etal., J Neurochem. 1997 Jun;68(6):2263-72.
16. The localization of messenger ribonucleic acids for somatostatin receptors 1, 2, and 3 in rat testis. Zhu LJ, etal., Endocrinology. 1998 Jan;139(1):350-7.
Additional References at PubMed
PMID:9295322   PMID:11935411   PMID:16543371   PMID:17617126   PMID:18334641   PMID:18702662   PMID:18793718   PMID:18992731   PMID:19071123   PMID:22179047   PMID:22718903   PMID:22832925  
PMID:23029470   PMID:23351594   PMID:25926390   PMID:28154160   PMID:28176050   PMID:29522573  


Genomics

Comparative Map Data
Sstr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,973,049 - 111,980,250 (-)NCBIGRCr8
mRatBN7.27110,092,563 - 110,109,043 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,092,575 - 110,099,769 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,843,786 - 111,850,977 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,067,323 - 114,074,514 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,035,025 - 114,042,224 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,760,881 - 119,768,082 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,760,888 - 119,768,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,749,191 - 119,756,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,495,750 - 116,502,948 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,529,980 - 116,537,178 (-)NCBI
Celera7106,430,574 - 106,437,768 (-)NCBICelera
Cytogenetic Map7q34NCBI
SSTR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,204,237 - 37,220,548 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,204,237 - 37,212,477 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,600,277 - 37,608,517 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,932,191 - 35,938,299 (-)NCBINCBI36Build 36hg18NCBI36
Build 342235,926,744 - 35,932,853NCBI
Celera2221,403,286 - 21,409,394 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2220,565,266 - 20,573,403 (-)NCBIHuRef
CHM1_12237,559,498 - 37,567,635 (-)NCBICHM1_1
T2T-CHM13v2.02237,664,155 - 37,680,477 (-)NCBIT2T-CHM13v2.0
Sstr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,421,214 - 78,433,565 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,421,208 - 78,428,885 (-)EnsemblGRCm39 Ensembl
GRCm381578,537,014 - 78,549,365 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,537,008 - 78,544,685 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,367,445 - 78,374,775 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,364,270 - 78,371,600 (-)NCBIMGSCv36mm8
Celera1579,999,612 - 80,006,947 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.55NCBI
Sstr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,677,693 - 23,683,939 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,677,693 - 23,683,939 (-)NCBIChiLan1.0ChiLan1.0
SSTR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,059,524 - 47,067,881 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12249,748,109 - 49,756,461 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,116,993 - 18,125,170 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12235,951,884 - 35,960,143 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,954,232 - 35,955,488 (-)Ensemblpanpan1.1panPan2
SSTR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,324,067 - 27,332,570 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,329,174 - 27,330,451 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,284,056 - 27,285,333 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01028,116,305 - 28,124,854 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1028,116,601 - 28,124,837 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,843,123 - 27,844,400 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01028,151,844 - 28,153,121 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,329,709 - 28,330,986 (+)NCBIUU_Cfam_GSD_1.0
Sstr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,736,153 - 10,741,916 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,748,135 - 3,751,089 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,745,455 - 3,752,330 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSTR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,581,912 - 10,589,982 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,581,814 - 10,593,796 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.258,177,095 - 8,184,839 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SSTR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11919,908,562 - 19,916,787 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1919,910,898 - 19,912,154 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045105,910,866 - 105,919,617 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sstr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,619,078 - 10,626,754 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,623,360 - 10,626,759 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sstr3
147 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:394
Count of miRNA genes:228
Interacting mature miRNAs:259
Transcripts:ENSRNOT00000009612
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
D7Wox45  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,100,824 - 110,100,972 (+)MAPPERmRatBN7.2
Rnor_6.07119,769,138 - 119,769,285NCBIRnor6.0
Rnor_5.07119,757,448 - 119,757,595UniSTSRnor5.0
RGSC_v3.47116,504,004 - 116,504,151UniSTSRGSC3.4
Celera7106,438,824 - 106,438,971UniSTS
Cytogenetic Map7q34UniSTS
RH137873  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,092,590 - 110,092,713 (+)MAPPERmRatBN7.2
Rnor_6.07119,760,904 - 119,761,026NCBIRnor6.0
Rnor_5.07119,749,214 - 119,749,336UniSTSRnor5.0
RGSC_v3.47116,495,770 - 116,495,892UniSTSRGSC3.4
Celera7106,430,594 - 106,430,716UniSTS
RH 3.4 Map7815.1UniSTS
Cytogenetic Map7q34UniSTS
Smstr3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,094,513 - 110,094,652 (+)MAPPERmRatBN7.2
Rnor_6.07119,762,827 - 119,762,965NCBIRnor6.0
Rnor_5.07119,751,137 - 119,751,275UniSTSRnor5.0
RGSC_v3.47116,497,693 - 116,497,831UniSTSRGSC3.4
Celera7106,432,517 - 106,432,655UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 6 48 105 89 88 57 25 57 6 210 94 85 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000009612   ⟹   ENSRNOP00000009612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,092,575 - 110,099,769 (-)Ensembl
Rnor_6.0 Ensembl7119,760,888 - 119,768,082 (-)Ensembl
RefSeq Acc Id: NM_133522   ⟹   NP_598206
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87111,973,052 - 111,980,250 (-)NCBI
mRatBN7.27110,092,571 - 110,099,769 (-)NCBI
Rnor_6.07119,760,884 - 119,768,082 (-)NCBI
Rnor_5.07119,749,191 - 119,756,392 (-)NCBI
RGSC_v3.47116,495,750 - 116,502,948 (-)RGD
Celera7106,430,574 - 106,437,768 (-)RGD
Sequence:
RefSeq Acc Id: XM_063262947   ⟹   XP_063119017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87111,973,049 - 111,979,394 (-)NCBI
Protein Sequences
Protein RefSeqs NP_598206 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119017 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD21009 (Get FASTA)   NCBI Sequence Viewer  
  CAA45130 (Get FASTA)   NCBI Sequence Viewer  
  EDM15860 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009612
  ENSRNOP00000009612.2
GenBank Protein P30936 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_598206   ⟸   NM_133522
- UniProtKB: P30936 (UniProtKB/Swiss-Prot),   A6HSL2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009612   ⟸   ENSRNOT00000009612
RefSeq Acc Id: XP_063119017   ⟸   XM_063262947
- Peptide Label: isoform X1
- UniProtKB: P30936 (UniProtKB/Swiss-Prot),   A6HSL2 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30936-F1-model_v2 AlphaFold P30936 1-428 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620308 AgrOrtholog
BioCyc Gene G2FUF-32807 BioCyc
Ensembl Genes ENSRNOG00000007332 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009612 ENTREZGENE
  ENSRNOT00000009612.4 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Somatstn_rcpt UniProtKB/Swiss-Prot
  Somatstn_rcpt_3 UniProtKB/Swiss-Prot
KEGG Report rno:171044 UniProtKB/Swiss-Prot
NCBI Gene 171044 ENTREZGENE
PANTHER NEUROPEPTIDES RECEPTOR UniProtKB/Swiss-Prot
  SOMATOSTATIN RECEPTOR TYPE 3 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Sstr3 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  SOMATOSTATNR UniProtKB/Swiss-Prot
  SOMATOSTTN3R UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007332 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A6HSL2 ENTREZGENE, UniProtKB/TrEMBL
  P30936 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-08 Sstr3  somatostatin receptor 3  SSTR  hypothetical gene supported by NM_133522  Data merged from RGD:1583749 1643240 APPROVED
2006-11-19 SSTR  hypothetical gene supported by NM_133522      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Sstr3  somatostatin receptor 3  Smstr28  somatostatin receptor 28  Symbol and Name updated 1299863 APPROVED
2002-08-07 Smstr28  somatostatin receptor 28      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expressed in the granular and Purkinje cell layers of the cerebellum also expressed in the large cells of the hypoglossal nucleus of the brain stem 634172
gene_physical_interaction has a high binding affinity for somatostatin-28 and somatostatin-14 634172
gene_protein protein is 428 amino acids in size and has a mass of 47 kDa 634172