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Gene: Oprk1 (opioid receptor, kappa 1) Rattus norvegicus
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Symbol: Oprk1
Name: opioid receptor, kappa 1
Description: Exhibits receptor serine/threonine kinase binding activity. Involved in several processes, including conditioned place preference; positive regulation of ion transport; and response to alkaloid. Localizes to several cellular components, including the integral component of synaptic membrane; integral component of synaptic vesicle membrane; and perikaryon. Used to study heroin dependence; myocardial infarction; and withdrawal disorder. Orthologous to human OPRK1 (opioid receptor kappa 1); PARTICIPATES IN nalbuphine pharmacodynamics pathway; INTERACTS WITH (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin; (R)-noradrenaline; (R,R)-tramadol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: K-OR-1; kappa-type opioid receptor; KOR-1
Orthologs:
Homo sapiens (human) : OPRK1 (opioid receptor kappa 1)  HGNC  Alliance
Mus musculus (house mouse) : Oprk1 (opioid receptor, kappa 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oprk1 (opioid receptor kappa 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPRK1 (opioid receptor kappa 1)
Canis lupus familiaris (dog) : OPRK1 (opioid receptor kappa 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oprk1 (opioid receptor kappa 1)
Sus scrofa (pig) : OPRK1 (opioid receptor kappa 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0513,742,655 - 13,760,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl513,744,658 - 13,760,305 (-)Ensembl
Rnor_5.0518,519,763 - 18,534,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4514,040,848 - 14,055,273 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1514,037,659 - 14,055,460 (-)NCBI
Celera513,240,420 - 13,258,214 (-)NCBICelera
Cytogenetic Map5q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Oprk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69426
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.