Gene: Oprk1 (opioid receptor, kappa 1) Rattus norvegicus
Symbol: Oprk1
Name: opioid receptor, kappa 1
Description: ENCODES a protein that exhibits receptor serine/threonine kinase binding; dynorphin receptor activity (ortholog); opioid receptor activity (ortholog); INVOLVED IN behavioral response to cocaine; cellular response to glucose stimulus; cellular response to lipopolysaccharide; PARTICIPATES IN nalbuphine pharmacodynamics pathway; ASSOCIATED WITH Cardiac Arrhythmias; conditioned taste aversion; Diabetes Mellitus, Experimental ; FOUND IN axon terminus; dendrite; integral component of postsynaptic membrane; INTERACTS WITH (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin; (R)-noradrenaline; (R,R)-tramadol
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: K-OR-1; kappa-type opioid receptor; KOR-1
Homo sapiens (human) : OPRK1 (opioid receptor kappa 1)  HGNC  Alliance
Mus musculus (house mouse) : Oprk1 (opioid receptor, kappa 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oprk1 (opioid receptor kappa 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPRK1 (opioid receptor kappa 1)
Canis lupus familiaris (dog) : OPRK1 (opioid receptor kappa 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oprk1 (opioid receptor kappa 1)
Sus scrofa (pig) : OPRK1 (opioid receptor kappa 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0513,742,655 - 13,760,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0518,519,763 - 18,534,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4514,040,848 - 14,055,273 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1514,037,659 - 14,055,460 (-)NCBI
Celera513,240,420 - 13,258,214 (-)NCBICelera
Cytogenetic Map5q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Oprk1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69426
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE