Sstr1 (somatostatin receptor 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sstr1 (somatostatin receptor 1) Rattus norvegicus
Analyze
Symbol: Sstr1
Name: somatostatin receptor 1
RGD ID: 3762
Description: Enables somatostatin receptor activity. Involved in several processes, including brain development; cellular response to estradiol stimulus; and spermatogenesis. Located in cytoplasm and plasma membrane. Orthologous to human SSTR1 (somatostatin receptor 1); PARTICIPATES IN somatostatin signaling pathway; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gpcrrna; RNGPCRRNA; Somatostatin receptor subtype 1; somatostatin receptor type 1; SRIF-2; SS-1-R; SS1-R; SS1R
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2675,832,292 - 75,836,806 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl675,832,530 - 75,836,802 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx676,235,331 - 76,239,631 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0676,534,673 - 76,538,973 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0675,962,144 - 75,966,444 (+)NCBIRnor_WKY
Rnor_6.0679,252,914 - 79,258,611 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl679,254,339 - 79,258,611 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0688,783,414 - 88,787,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4678,803,393 - 78,806,978 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1678,806,518 - 78,810,104 (+)NCBI
Celera674,603,631 - 74,607,903 (+)NCBICelera
RH 3.4 Map6546.4RGD
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. An intracellular multi-effector complex mediates somatostatin receptor 1 activation of phospho-tyrosine phosphatase eta. Arena S, etal., Mol Endocrinol. 2007 Jan;21(1):229-46. Epub 2006 Oct 4.
2. Identification of multiple somatostatin receptors in the rat somatosensory cortex during development. Bologna E and Leroux P, J Comp Neurol. 2000 May 15;420(4):466-80.
3. Pituitary and hypothalamic somatostatin receptor subtype messenger ribonucleic acid expression in the food-deprived and diabetic rat. Bruno JF, etal., Endocrinology. 1994 Nov;135(5):1787-92.
4. Effect of 17beta-estradiol on somatostatin receptor expression and inhibitory effects on growth hormone and prolactin release in rat pituitary cell cultures. Djordjijevic D, etal., Endocrinology. 1998 May;139(5):2272-7.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy. Kumar U, etal., Endocrinology. 1997 Oct;138(10):4473-6.
8. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
9. Cloning and expression of a rat somatostatin receptor enriched in brain. Li XJ, etal., J Biol Chem 1992 Oct 25;267(30):21307-12.
10. Cloning of a cDNA encoding a novel putative G-protein-coupled receptor expressed in specific rat brain regions. Meyerhof W, etal., DNA Cell Biol 1991 Nov;10(9):689-94.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Activation of rat thymocytes selectively upregulates the expression of somatostatin receptor subtype-1. Sedqi M, etal., Biochem Mol Biol Int 1996 Feb;38(1):103-12.
16. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
17. Differential expression of multiple somatostatin receptors in the rat cerebellum during development. Viollet C, etal., J Neurochem. 1997 Jun;68(6):2263-72.
18. The localization of messenger ribonucleic acids for somatostatin receptors 1, 2, and 3 in rat testis. Zhu LJ, etal., Endocrinology. 1998 Jan;139(1):350-7.
Additional References at PubMed
PMID:1346068   PMID:7929134   PMID:9166719   PMID:10734105   PMID:15618885   PMID:16379030   PMID:16543371   PMID:17170097   PMID:17617126   PMID:18566118   PMID:19553459   PMID:20439489  
PMID:24368669   PMID:24978951   PMID:25035058   PMID:25926390   PMID:29522573  


Genomics

Comparative Map Data
Sstr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2675,832,292 - 75,836,806 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl675,832,530 - 75,836,802 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx676,235,331 - 76,239,631 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0676,534,673 - 76,538,973 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0675,962,144 - 75,966,444 (+)NCBIRnor_WKY
Rnor_6.0679,252,914 - 79,258,611 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl679,254,339 - 79,258,611 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0688,783,414 - 88,787,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4678,803,393 - 78,806,978 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1678,806,518 - 78,810,104 (+)NCBI
Celera674,603,631 - 74,607,903 (+)NCBICelera
RH 3.4 Map6546.4RGD
Cytogenetic Map6q23NCBI
SSTR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381438,207,904 - 38,213,067 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1438,207,904 - 38,213,067 (+)EnsemblGRCh38hg38GRCh38
GRCh371438,677,109 - 38,682,272 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361437,746,955 - 37,752,019 (+)NCBINCBI36Build 36hg18NCBI36
Build 341437,746,954 - 37,752,019NCBI
Celera1418,541,740 - 18,546,804 (+)NCBICelera
Cytogenetic Map14q21.1NCBI
HuRef1418,792,180 - 18,797,244 (+)NCBIHuRef
CHM1_11438,674,961 - 38,680,025 (+)NCBICHM1_1
T2T-CHM13v2.01432,396,603 - 32,401,766 (+)NCBIT2T-CHM13v2.0
Sstr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391258,258,230 - 58,262,822 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1258,258,558 - 58,261,230 (+)EnsemblGRCm39 Ensembl
GRCm381258,211,421 - 58,216,037 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1258,211,772 - 58,214,444 (+)EnsemblGRCm38mm10GRCm38
MGSCv371259,312,791 - 59,317,023 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361259,129,816 - 59,132,456 (+)NCBIMGSCv36mm8
Celera1259,362,952 - 59,367,171 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1225.61NCBI
Sstr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540922,889,800 - 22,894,480 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540922,889,800 - 22,894,480 (-)NCBIChiLan1.0ChiLan1.0
SSTR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11437,327,348 - 37,332,961 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1437,329,309 - 37,330,484 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01418,968,969 - 18,973,560 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SSTR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1816,571,069 - 16,575,730 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha816,377,472 - 16,378,647 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0816,688,125 - 16,691,797 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl816,688,172 - 16,689,347 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1816,381,728 - 16,382,903 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0816,439,948 - 16,441,123 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0816,740,560 - 16,741,735 (+)NCBIUU_Cfam_GSD_1.0
Sstr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864048,558,403 - 48,563,242 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649412,065,473 - 12,066,648 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493649412,065,388 - 12,067,759 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSTR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl761,890,563 - 61,894,978 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1761,890,560 - 61,900,567 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2766,593,626 - 66,599,948 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SSTR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12415,000,190 - 15,006,757 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2415,003,116 - 15,004,291 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660534,033,896 - 4,039,724 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sstr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248137,539,304 - 7,540,479 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248137,538,104 - 7,543,836 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sstr1
11 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:224
Count of miRNA genes:155
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000073970
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)67222764181132889Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat

Markers in Region
D6Wox18  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,836,455 - 75,836,697 (+)MAPPERmRatBN7.2
Rnor_6.0679,258,265 - 79,258,506NCBIRnor6.0
Rnor_5.0688,787,651 - 88,787,892UniSTSRnor5.0
RGSC_v3.4678,806,636 - 78,806,877UniSTSRGSC3.4
Celera674,607,557 - 74,607,798UniSTS
Cytogenetic Map6q23UniSTS
D6Wox19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,836,959 - 75,837,048 (+)MAPPERmRatBN7.2
Rnor_6.0679,258,769 - 79,258,857NCBIRnor6.0
Rnor_5.0688,788,155 - 88,788,243UniSTSRnor5.0
RGSC_v3.4678,807,140 - 78,807,228UniSTSRGSC3.4
Celera674,608,061 - 74,608,149UniSTS
Cytogenetic Map6q23UniSTS
Smstr1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,834,189 - 75,834,325 (+)MAPPERmRatBN7.2
Rnor_6.0679,255,999 - 79,256,134NCBIRnor6.0
Rnor_5.0688,785,385 - 88,785,520UniSTSRnor5.0
RGSC_v3.4678,804,370 - 78,804,505UniSTSRGSC3.4
Celera674,605,291 - 74,605,426UniSTS
Cytogenetic Map6q23UniSTS
RH94712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,835,631 - 75,835,759 (+)MAPPERmRatBN7.2
Rnor_6.0679,257,441 - 79,257,568NCBIRnor6.0
Rnor_5.0688,786,827 - 88,786,954UniSTSRnor5.0
RGSC_v3.4678,805,812 - 78,805,939UniSTSRGSC3.4
Celera674,606,733 - 74,606,860UniSTS
RH 3.4 Map6546.4UniSTS
Cytogenetic Map6q23UniSTS
RH138685  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,835,840 - 75,835,960 (+)MAPPERmRatBN7.2
Rnor_6.0679,257,650 - 79,257,769NCBIRnor6.0
Rnor_5.0688,787,036 - 88,787,155UniSTSRnor5.0
RGSC_v3.4678,806,021 - 78,806,140UniSTSRGSC3.4
Celera674,606,942 - 74,607,061UniSTS
RH 3.4 Map6545.99UniSTS
Cytogenetic Map6q23UniSTS
UniSTS:495999  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,834,180 - 75,834,271 (+)MAPPERmRatBN7.2
Rnor_6.0679,255,990 - 79,256,080NCBIRnor6.0
Rnor_5.0688,785,376 - 88,785,466UniSTSRnor5.0
RGSC_v3.4678,804,361 - 78,804,451UniSTSRGSC3.4
Celera674,605,282 - 74,605,372UniSTS
Cytogenetic Map6q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43
Low 3 2 29 27 11
Below cutoff 35 22 11 14 11 7 9 2 33 7 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000073970   ⟹   ENSRNOP00000067355
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl675,832,530 - 75,836,802 (+)Ensembl
Rnor_6.0 Ensembl679,254,339 - 79,258,611 (+)Ensembl
RefSeq Acc Id: NM_012719   ⟹   NP_036851
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2675,832,530 - 75,836,802 (+)NCBI
Rnor_6.0679,254,339 - 79,258,611 (+)NCBI
Rnor_5.0688,783,414 - 88,787,997 (+)NCBI
RGSC_v3.4678,803,393 - 78,806,978 (+)RGD
Celera674,603,631 - 74,607,903 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240115   ⟹   XP_006240177
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2675,832,292 - 75,836,806 (+)NCBI
Rnor_6.0679,252,914 - 79,258,611 (+)NCBI
Rnor_5.0688,783,414 - 88,787,997 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_036851 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240177 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL76096 (Get FASTA)   NCBI Sequence Viewer  
  CAA44193 (Get FASTA)   NCBI Sequence Viewer  
  EDM03458 (Get FASTA)   NCBI Sequence Viewer  
  P28646 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_036851   ⟸   NM_012719
- UniProtKB: P28646 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240177   ⟸   XM_006240115
- Peptide Label: isoform X1
- UniProtKB: P28646 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067355   ⟸   ENSRNOT00000073970

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28646-F1-model_v2 AlphaFold P28646 1-391 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3762 AgrOrtholog
BioCyc Gene G2FUF-37401 BioCyc
Ensembl Genes ENSRNOG00000048145 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000067355 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000073970 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Somatstn_rcpt UniProtKB/Swiss-Prot
  Somatstn_rcpt_1 UniProtKB/Swiss-Prot
KEGG Report rno:25033 UniProtKB/Swiss-Prot
NCBI Gene 25033 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Sstr1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  SOMATOSTATNR UniProtKB/Swiss-Prot
  SOMATOSTTN1R UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
TIGR TC202357
UniProt P28646 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Sstr1  somatostatin receptor 1    Somatostatin receptor subtype 1  Symbol and Name updated 629477 APPROVED
2002-06-10 Sstr1  Somatostatin receptor subtype 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression preferentially expressed in brain, particularly in cerebral cortex and hippocampus 730160
gene_physical_interaction binds somatostatin-14 730160
gene_protein 391 amino acids with seven potential transmembrane domains 730160