Sstr1 (somatostatin receptor 1) - Rat Genome Database

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Gene: Sstr1 (somatostatin receptor 1) Rattus norvegicus
Analyze
Symbol: Sstr1
Name: somatostatin receptor 1
RGD ID: 3762
Description: Exhibits somatostatin receptor activity. Involved in several processes, including brain development; cellular response to estradiol stimulus; and spermatogenesis. Localizes to cytoplasm and plasma membrane. Orthologous to human SSTR1 (somatostatin receptor 1); PARTICIPATES IN somatostatin signaling pathway; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gpcrrna; RNGPCRRNA; Somatostatin receptor subtype 1; somatostatin receptor type 1; SRIF-2; SS-1-R; SS1-R; SS1R
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2675,832,292 - 75,836,806 (+)NCBI
Rnor_6.0 Ensembl679,254,339 - 79,258,611 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0679,252,914 - 79,258,611 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0688,783,414 - 88,787,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4678,803,393 - 78,806,978 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1678,806,518 - 78,810,104 (+)NCBI
Celera674,603,631 - 74,607,903 (+)NCBICelera
RH 3.4 Map6546.4RGD
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1346068   PMID:7929134   PMID:9166719   PMID:10734105   PMID:15618885   PMID:16379030   PMID:16543371   PMID:17170097   PMID:17617126   PMID:18566118   PMID:19553459   PMID:20439489  
PMID:24368669   PMID:24978951   PMID:25035058   PMID:25926390   PMID:29522573  


Genomics

Comparative Map Data
Sstr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2675,832,292 - 75,836,806 (+)NCBI
Rnor_6.0 Ensembl679,254,339 - 79,258,611 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0679,252,914 - 79,258,611 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0688,783,414 - 88,787,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4678,803,393 - 78,806,978 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1678,806,518 - 78,810,104 (+)NCBI
Celera674,603,631 - 74,607,903 (+)NCBICelera
RH 3.4 Map6546.4RGD
Cytogenetic Map6q23NCBI
SSTR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1438,207,904 - 38,213,067 (+)EnsemblGRCh38hg38GRCh38
GRCh381438,207,904 - 38,213,067 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371438,677,109 - 38,682,272 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361437,746,955 - 37,752,019 (+)NCBINCBI36hg18NCBI36
Build 341437,746,954 - 37,752,019NCBI
Celera1418,541,740 - 18,546,804 (+)NCBI
Cytogenetic Map14q21.1NCBI
HuRef1418,792,180 - 18,797,244 (+)NCBIHuRef
CHM1_11438,674,961 - 38,680,025 (+)NCBICHM1_1
Sstr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391258,258,230 - 58,262,822 (+)NCBIGRCm39mm39
GRCm39 Ensembl1258,258,558 - 58,261,230 (+)Ensembl
GRCm381258,211,421 - 58,216,037 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1258,211,772 - 58,214,444 (+)EnsemblGRCm38mm10GRCm38
MGSCv371259,312,791 - 59,317,023 (+)NCBIGRCm37mm9NCBIm37
MGSCv361259,129,816 - 59,132,456 (+)NCBImm8
Celera1259,362,952 - 59,367,171 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1225.61NCBI
Sstr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540922,889,800 - 22,894,480 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540922,889,800 - 22,894,480 (-)NCBIChiLan1.0ChiLan1.0
SSTR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11437,327,348 - 37,332,961 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1437,329,309 - 37,330,484 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01418,968,969 - 18,973,560 (+)NCBIMhudiblu_PPA_v0panPan3
SSTR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1816,571,069 - 16,575,730 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha816,377,472 - 16,378,647 (+)NCBI
ROS_Cfam_1.0816,688,125 - 16,691,797 (+)NCBI
UMICH_Zoey_3.1816,381,728 - 16,382,903 (+)NCBI
UNSW_CanFamBas_1.0816,439,948 - 16,441,123 (+)NCBI
UU_Cfam_GSD_1.0816,740,560 - 16,741,735 (+)NCBI
Sstr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864048,558,403 - 48,563,242 (+)NCBI
SpeTri2.0NW_00493649412,065,388 - 12,067,759 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSTR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl761,890,563 - 61,894,978 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1761,890,560 - 61,900,567 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2766,593,626 - 66,599,948 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SSTR1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12415,000,190 - 15,006,757 (+)NCBI
ChlSab1.1 Ensembl2415,003,116 - 15,004,291 (+)Ensembl
Sstr1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248137,538,104 - 7,543,836 (+)NCBI

Position Markers
D6Wox18  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,836,455 - 75,836,697 (+)MAPPER
Rnor_6.0679,258,265 - 79,258,506NCBIRnor6.0
Rnor_5.0688,787,651 - 88,787,892UniSTSRnor5.0
RGSC_v3.4678,806,636 - 78,806,877UniSTSRGSC3.4
Celera674,607,557 - 74,607,798UniSTS
Cytogenetic Map6q23UniSTS
D6Wox19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,836,959 - 75,837,048 (+)MAPPER
Rnor_6.0679,258,769 - 79,258,857NCBIRnor6.0
Rnor_5.0688,788,155 - 88,788,243UniSTSRnor5.0
RGSC_v3.4678,807,140 - 78,807,228UniSTSRGSC3.4
Celera674,608,061 - 74,608,149UniSTS
Cytogenetic Map6q23UniSTS
Smstr1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,834,189 - 75,834,325 (+)MAPPER
Rnor_6.0679,255,999 - 79,256,134NCBIRnor6.0
Rnor_5.0688,785,385 - 88,785,520UniSTSRnor5.0
RGSC_v3.4678,804,370 - 78,804,505UniSTSRGSC3.4
Celera674,605,291 - 74,605,426UniSTS
Cytogenetic Map6q23UniSTS
RH94712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,835,631 - 75,835,759 (+)MAPPER
Rnor_6.0679,257,441 - 79,257,568NCBIRnor6.0
Rnor_5.0688,786,827 - 88,786,954UniSTSRnor5.0
RGSC_v3.4678,805,812 - 78,805,939UniSTSRGSC3.4
Celera674,606,733 - 74,606,860UniSTS
RH 3.4 Map6546.4UniSTS
Cytogenetic Map6q23UniSTS
RH138685  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,835,840 - 75,835,960 (+)MAPPER
Rnor_6.0679,257,650 - 79,257,769NCBIRnor6.0
Rnor_5.0688,787,036 - 88,787,155UniSTSRnor5.0
RGSC_v3.4678,806,021 - 78,806,140UniSTSRGSC3.4
Celera674,606,942 - 74,607,061UniSTS
RH 3.4 Map6545.99UniSTS
Cytogenetic Map6q23UniSTS
UniSTS:495999  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2675,834,180 - 75,834,271 (+)MAPPER
Rnor_6.0679,255,990 - 79,256,080NCBIRnor6.0
Rnor_5.0688,785,376 - 88,785,466UniSTSRnor5.0
RGSC_v3.4678,804,361 - 78,804,451UniSTSRGSC3.4
Celera674,605,282 - 74,605,372UniSTS
Cytogenetic Map6q23UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)62537030111715717Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)67009971115379601Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62204285484763421Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62204285484763421Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63436743680490628Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63626028884763275Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63810630883106308Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64167904686679046Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64167904686679046Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64167904686679046Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)648432758108268790Rat
4889848Pur25Proteinuria QTL 25140.003total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65980306594001333Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)660606431108154445Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)660606431108154445Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)662263348107263348Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)666129520111129520Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)671206251116206251Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)675449871120449871Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)675623277120276465Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)675623277120623277Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)675623277136143011Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)675623277136426962Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)67562339384763275Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)675623393136142742Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)675623393136142742Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)676902247114203334Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:224
Count of miRNA genes:155
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000073970
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43
Low 3 2 29 27 11
Below cutoff 35 22 11 14 11 7 9 2 33 7 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000073970   ⟹   ENSRNOP00000067355
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl679,254,339 - 79,258,611 (+)Ensembl
RefSeq Acc Id: NM_012719   ⟹   NP_036851
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2675,832,530 - 75,836,802 (+)NCBI
Rnor_6.0679,254,339 - 79,258,611 (+)NCBI
Rnor_5.0688,783,414 - 88,787,997 (+)NCBI
RGSC_v3.4678,803,393 - 78,806,978 (+)RGD
Celera674,603,631 - 74,607,903 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240115   ⟹   XP_006240177
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2675,832,292 - 75,836,806 (+)NCBI
Rnor_6.0679,252,914 - 79,258,611 (+)NCBI
Rnor_5.0688,783,414 - 88,787,997 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_036851 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240177 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL76096 (Get FASTA)   NCBI Sequence Viewer  
  CAA44193 (Get FASTA)   NCBI Sequence Viewer  
  EDM03458 (Get FASTA)   NCBI Sequence Viewer  
  P28646 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_036851   ⟸   NM_012719
- UniProtKB: P28646 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240177   ⟸   XM_006240115
- Peptide Label: isoform X1
- UniProtKB: P28646 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067355   ⟸   ENSRNOT00000073970

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3762 AgrOrtholog
Ensembl Genes ENSRNOG00000048145 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000067355 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000073970 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Somatstn_rcpt UniProtKB/Swiss-Prot
  Somatstn_rcpt_1 UniProtKB/Swiss-Prot
KEGG Report rno:25033 UniProtKB/Swiss-Prot
NCBI Gene 25033 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Sstr1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  SOMATOSTATNR UniProtKB/Swiss-Prot
  SOMATOSTTN1R UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
TIGR TC202357
UniProt P28646 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Sstr1  somatostatin receptor 1    Somatostatin receptor subtype 1  Symbol and Name updated 629477 APPROVED
2002-06-10 Sstr1  Somatostatin receptor subtype 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression preferentially expressed in brain, particularly in cerebral cortex and hippocampus 730160
gene_physical_interaction binds somatostatin-14 730160
gene_protein 391 amino acids with seven potential transmembrane domains 730160