Sstr1 (somatostatin receptor 1) - Rat Genome Database

Name: Sstr1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Sstr1 (somatostatin receptor 1) Rattus norvegicus

Analyze

Symbol:

Sstr1

Name:

somatostatin receptor 1

RGD ID:

3762

Description:

Enables somatostatin receptor activity. Involved in several processes, including brain development; cellular response to estradiol stimulus; and spermatogenesis. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of G protein-coupled receptor heterodimeric complex and G protein-coupled receptor homodimeric complex. Predicted to be active in neuron projection. Orthologous to human SSTR1 (somatostatin receptor 1); PARTICIPATES IN somatostatin signaling pathway; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Gpcrrna; RNGPCRRNA; Somatostatin receptor subtype 1; somatostatin receptor type 1; SRIF-2; SS-1-R; SS1-R; SS1R

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SSTR1 (somatostatin receptor 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Sstr1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sstr1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SSTR1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SSTR1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sstr1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SSTR1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SSTR1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sstr1 (somatostatin receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SSTR1 (somatostatin receptor 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sstr1 (somatostatin receptor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sstr1a (somatostatin receptor 1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	AstC-R1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	npr-16	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	npr-24	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	AstC-R2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	81,567,237 - 81,571,759 (+)	NCBI		GRCr8
mRatBN7.2	6	75,832,292 - 75,836,806 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	75,832,530 - 75,836,802 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	76,235,331 - 76,239,631 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	76,534,673 - 76,538,973 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	75,962,144 - 75,966,444 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	79,252,914 - 79,258,611 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	79,254,339 - 79,258,611 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	88,783,414 - 88,787,997 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	78,803,393 - 78,806,978 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	78,806,518 - 78,810,104 (+)	NCBI
Celera	6	74,603,631 - 74,607,903 (+)	NCBI		Celera
RH 3.4 Map	6	546.4	RGD
Cytogenetic Map	6	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain-Lung-Thyroid Syndrome (ISO)

Experimental Diabetes Mellitus (IEP)

genetic disease (ISO)

neuroendocrine tumor (ISO)

pancreatic cancer (ISO)

status epilepticus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-pilocarpine (EXP)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

amitriptyline (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

bleomycin A2 (EXP)

cadmium dichloride (EXP)

CGP 52608 (ISO)

cocaine (EXP)

dexamethasone (ISO)

dextran sulfate (ISO)

diazinon (EXP)

dibutyl phthalate (EXP)

dichloroacetic acid (ISO)

dinitrogen (ISO)

ethanol (EXP,ISO)

folic acid (ISO)

indometacin (ISO)

iodoacetic acid (ISO)

ketamine (EXP)

Licochalcone B (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nickel atom (ISO)

octreotide (ISO)

ozone (ISO)

pasireotide (ISO)

potassium chromate (ISO)

progesterone (ISO)

silicon dioxide (EXP)

sodium arsenite (ISO)

somatostatin (ISO)

T-2 toxin (EXP)

Tesaglitazar (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to estradiol stimulus (IBA,IEP)

cellular response to leukemia inhibitory factor (ISO)

cerebellum development (IEP)

forebrain development (IEP)

G protein-coupled receptor signaling pathway (ISO)

glutamate receptor signaling pathway (ISO)

negative regulation of growth hormone secretion (ISO)

neuropeptide signaling pathway (IBA,ISO)

response to starvation (IEP)

somatostatin signaling pathway (IEA,ISO)

spermatogenesis (IEP)

T cell differentiation (NAS)

Cellular Component

cytoplasm (ISO)

G protein-coupled receptor heterodimeric complex (ISO)

G protein-coupled receptor homodimeric complex (ISO)

membrane (ISO)

neuron projection (IBA)

plasma membrane (ISO)

Molecular Function

neuropeptide binding (IBA)

protein binding (ISO)

protein heterodimerization activity (ISO)

protein homodimerization activity (ISO)

somatostatin receptor activity (IBA,IMP,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

somatostatin signaling pathway (IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	An intracellular multi-effector complex mediates somatostatin receptor 1 activation of phospho-tyrosine phosphatase eta.	Arena S, etal., Mol Endocrinol. 2007 Jan;21(1):229-46. Epub 2006 Oct 4.
2.	Identification of multiple somatostatin receptors in the rat somatosensory cortex during development.	Bologna E and Leroux P, J Comp Neurol. 2000 May 15;420(4):466-80.
3.	Pituitary and hypothalamic somatostatin receptor subtype messenger ribonucleic acid expression in the food-deprived and diabetic rat.	Bruno JF, etal., Endocrinology. 1994 Nov;135(5):1787-92.
4.	Effect of 17beta-estradiol on somatostatin receptor expression and inhibitory effects on growth hormone and prolactin release in rat pituitary cell cultures.	Djordjijevic D, etal., Endocrinology. 1998 May;139(5):2272-7.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
7.	Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy.	Kumar U, etal., Endocrinology. 1997 Oct;138(10):4473-6.
8.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
9.	Cloning and expression of a rat somatostatin receptor enriched in brain.	Li XJ, etal., J Biol Chem 1992 Oct 25;267(30):21307-12.
10.	Cloning of a cDNA encoding a novel putative G-protein-coupled receptor expressed in specific rat brain regions.	Meyerhof W, etal., DNA Cell Biol 1991 Nov;10(9):689-94.
11.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	GOA pipeline	RGD automated data pipeline
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Activation of rat thymocytes selectively upregulates the expression of somatostatin receptor subtype-1.	Sedqi M, etal., Biochem Mol Biol Int 1996 Feb;38(1):103-12.
16.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
17.	Differential expression of multiple somatostatin receptors in the rat cerebellum during development.	Viollet C, etal., J Neurochem. 1997 Jun;68(6):2263-72.
18.	The localization of messenger ribonucleic acids for somatostatin receptors 1, 2, and 3 in rat testis.	Zhu LJ, etal., Endocrinology. 1998 Jan;139(1):350-7.

Additional References at PubMed

PMID:1346068	PMID:7929134	PMID:9166719	PMID:10734105	PMID:15618885	PMID:16379030	PMID:16543371	PMID:17170097	PMID:17617126	PMID:18566118	PMID:19553459	PMID:20439489
PMID:24368669	PMID:24978951	PMID:25035058	PMID:25926390	PMID:29522573

Genomics

Comparative Map Data

Sstr1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	81,567,237 - 81,571,759 (+)	NCBI		GRCr8
mRatBN7.2	6	75,832,292 - 75,836,806 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	75,832,530 - 75,836,802 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	76,235,331 - 76,239,631 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	76,534,673 - 76,538,973 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	75,962,144 - 75,966,444 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	79,252,914 - 79,258,611 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	79,254,339 - 79,258,611 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	88,783,414 - 88,787,997 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	78,803,393 - 78,806,978 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	78,806,518 - 78,810,104 (+)	NCBI
Celera	6	74,603,631 - 74,607,903 (+)	NCBI		Celera
RH 3.4 Map	6	546.4	RGD
Cytogenetic Map	6	q23	NCBI

SSTR1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	38,207,904 - 38,213,067 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	38,207,904 - 38,213,067 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	38,677,109 - 38,682,272 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	37,746,955 - 37,752,019 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	37,746,954 - 37,752,019	NCBI
Celera	14	18,541,740 - 18,546,804 (+)	NCBI		Celera
Cytogenetic Map	14	q21.1	NCBI
HuRef	14	18,792,180 - 18,797,244 (+)	NCBI		HuRef
CHM1_1	14	38,674,961 - 38,680,025 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	32,396,603 - 32,401,766 (+)	NCBI		T2T-CHM13v2.0

Sstr1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	58,258,524 - 58,262,822 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	58,258,558 - 58,260,673 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	58,211,421 - 58,216,037 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	58,211,772 - 58,214,444 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	59,312,791 - 59,317,023 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	59,129,816 - 59,132,456 (+)	NCBI		MGSCv36	mm8
Celera	12	59,362,952 - 59,367,171 (+)	NCBI		Celera
Cytogenetic Map	12	C1	NCBI
cM Map	12	25.61	NCBI

Sstr1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	22,889,800 - 22,894,480 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	22,889,800 - 22,894,480 (-)	NCBI	ChiLan1.0	ChiLan1.0

SSTR1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	39,532,858 - 39,536,701 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	38,749,551 - 38,753,211 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	18,968,969 - 18,973,560 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	37,327,348 - 37,332,961 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	37,329,309 - 37,330,484 (+)	Ensembl	panpan1.1		panPan2

SSTR1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	16,571,069 - 16,575,730 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	16,377,472 - 16,378,647 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	16,688,125 - 16,691,797 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	16,688,172 - 16,689,347 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	16,381,728 - 16,382,903 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	16,439,948 - 16,441,123 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	16,740,560 - 16,741,735 (+)	NCBI		UU_Cfam_GSD_1.0

Sstr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	48,558,403 - 48,563,242 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936494	12,065,473 - 12,066,648 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936494	12,065,388 - 12,067,759 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SSTR1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	61,890,563 - 61,894,978 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	61,890,560 - 61,900,567 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	66,593,626 - 66,599,948 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SSTR1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	15,000,190 - 15,006,757 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	15,003,116 - 15,004,291 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	4,033,896 - 4,039,724 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sstr1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	7,539,304 - 7,540,479 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624813	7,538,104 - 7,543,836 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sstr1
14 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	224
Count of miRNA genes:	155
Interacting mature miRNAs:	187
Transcripts:	ENSRNOT00000073970
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	33309549	81132889	Rat
1300143	Rf14	Renal function QTL 14	2.92		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	34434137	77102317	Rat
634307	Bp141	Blood pressure QTL 141	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	35230417	80230417	Rat
9590290	Uminl2	Urine mineral level QTL 2	3.96	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	6	38783989	83783989	Rat
9590306	Scort18	Serum corticosterone level QTL 18	2.88	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
9590140	Scort4	Serum corticosterone level QTL 4	14.49	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
634330	Pia16	Pristane induced arthritis QTL 16	3.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	6	45790088	104200226	Rat
4889848	Pur25	Proteinuria QTL 25	14	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	56728562	90198260	Rat
6893332	Cm74	Cardiac mass QTL 74	0.4	0.64	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	57730540	104085867	Rat
1558641	Cm47	Cardiac mass QTL 47	2.9	0.001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	6	57730540	104085867	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	58632962	103632962	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	61747639	106747639	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
1641904	Alcrsp4	Alcohol response QTL 4			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	6	67262953	112262953	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	71201409	116201409	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	72202632	115200186	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72202632	117202632	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72227641	81132889	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	73463459	109394713	Rat

Markers in Region

D6Wox18

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	75,836,455 - 75,836,697 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	79,258,265 - 79,258,506	NCBI	Rnor6.0
Rnor_5.0	6	88,787,651 - 88,787,892	UniSTS	Rnor5.0
RGSC_v3.4	6	78,806,636 - 78,806,877	UniSTS	RGSC3.4
Celera	6	74,607,557 - 74,607,798	UniSTS
Cytogenetic Map	6	q23	UniSTS

D6Wox19

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	75,836,959 - 75,837,048 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	79,258,769 - 79,258,857	NCBI	Rnor6.0
Rnor_5.0	6	88,788,155 - 88,788,243	UniSTS	Rnor5.0
RGSC_v3.4	6	78,807,140 - 78,807,228	UniSTS	RGSC3.4
Celera	6	74,608,061 - 74,608,149	UniSTS
Cytogenetic Map	6	q23	UniSTS

Smstr1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	75,834,189 - 75,834,325 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	79,255,999 - 79,256,134	NCBI	Rnor6.0
Rnor_5.0	6	88,785,385 - 88,785,520	UniSTS	Rnor5.0
RGSC_v3.4	6	78,804,370 - 78,804,505	UniSTS	RGSC3.4
Celera	6	74,605,291 - 74,605,426	UniSTS
Cytogenetic Map	6	q23	UniSTS

RH94712

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	75,835,631 - 75,835,759 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	79,257,441 - 79,257,568	NCBI	Rnor6.0
Rnor_5.0	6	88,786,827 - 88,786,954	UniSTS	Rnor5.0
RGSC_v3.4	6	78,805,812 - 78,805,939	UniSTS	RGSC3.4
Celera	6	74,606,733 - 74,606,860	UniSTS
RH 3.4 Map	6	546.4	UniSTS
Cytogenetic Map	6	q23	UniSTS

RH138685

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	75,835,840 - 75,835,960 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	79,257,650 - 79,257,769	NCBI	Rnor6.0
Rnor_5.0	6	88,787,036 - 88,787,155	UniSTS	Rnor5.0
RGSC_v3.4	6	78,806,021 - 78,806,140	UniSTS	RGSC3.4
Celera	6	74,606,942 - 74,607,061	UniSTS
RH 3.4 Map	6	545.99	UniSTS
Cytogenetic Map	6	q23	UniSTS

UniSTS:495999

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	75,834,180 - 75,834,271 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	79,255,990 - 79,256,080	NCBI	Rnor6.0
Rnor_5.0	6	88,785,376 - 88,785,466	UniSTS	Rnor5.0
RGSC_v3.4	6	78,804,361 - 78,804,451	UniSTS	RGSC3.4
Celera	6	74,605,282 - 74,605,372	UniSTS
Cytogenetic Map	6	q23	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									43
Low	3		2						29		27	11
Below cutoff		35	22	11	14	11	7	9	2	33	7		7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240115	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L02915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M97656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X62314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000073970 ⟹ ENSRNOP00000067355

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	75,832,530 - 75,836,802 (+)	Ensembl
Rnor_6.0 Ensembl	6	79,254,339 - 79,258,611 (+)	Ensembl

RefSeq Acc Id:

NM_012719 ⟹ NP_036851

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	81,567,483 - 81,571,755 (+)	NCBI
mRatBN7.2	6	75,832,530 - 75,836,802 (+)	NCBI
Rnor_6.0	6	79,254,339 - 79,258,611 (+)	NCBI
Rnor_5.0	6	88,783,414 - 88,787,997 (+)	NCBI
RGSC_v3.4	6	78,803,393 - 78,806,978 (+)	RGD
Celera	6	74,603,631 - 74,607,903 (+)	NCBI

Sequence:

show sequence

AGACCTCACAAGCACTTTGCAAGGGCCATCTGGAGACATCGATTTAGGGACCCGACGACCTGAA
ATCTCCAGGTACAGTTTTGAAGAACTGGCAAGCAGGAAAGGAGCTGCTGACGCGATGGTGCTGC
TTATTAATCATTCATCAGTCCAGAGCCTTTCCACTTAATGGATATGTCGCGCTGGGCTCTAGCC
TCTTGACCTCTCCTCTCCTCTTCTTTCCACGCTCCAGTGTATCCAGGACCCCCAGAGCTGCAAG
AGACAGCGCTCAAGCAAGCAGCCGCCGGGCGTTGCGCCAGACGGCCTCAGTTGGAGCCGCGCTC
GCCACAGCTGCTGCGCGCTGCCGGGAGGCGCCAGGCGCCGGTGAGCTGTGAGCTTGGAGCCTTG
AGCCTAGGGAGGGCGCAGGCAGCAAGGGCGCAAGGTGAGCGTCCCAACCGGCGGCCACACCGGC
CCACTTCAGCTGGGATGTTCCCCAATGGCACCGCCCCCTCTCCCACCTCTTCTCCCAGCTCCAG
CCCAGGCGGCTGCGGGGAAGGAGTCTGCAGCAGGGGTCCCGGGTCCGGCGCTGCGGACGGCATG
GAAGAACCTGGACGAAACTCTTCCCAGAACGGGACTTTAAGCGAGGGTCAGGGTAGCGCCATTC
TCATCTCTTTCATCTACTCCGTGGTATGCTTGGTGGGACTGTGTGGGAACTCCATGGTCATTTA
CGTGATCCTGCGCTACGCCAAGATGAAGACCGCAACCAACATCTACATTCTAAACCTGGCCATT
GCTGATGAGCTGCTCATGCTCAGCGTGCCCTTTCTGGTCACTTCCACGCTGTTGCGCCACTGGC
CCTTTGGCGCGCTACTTTGCCGCCTGGTGCTCAGCGTGGATGCAGTCAACATGTTCACCAGCAT
CTACTGTCTGACTGTGCTTAGTGTGGACCGCTATGTGGCTGTGGTGCACCCGATCAAGGCAGCG
CGCTACCGTCGGCCCACTGTGGCCAAAGTAGTGAACCTGGGCGTGTGGGTGCTGTCGCTACTGG
TTATCTTGCCCATCGTGGTCTTCTCACGCACCGCAGCCAACAGCGATGGCACGGTGGCCTGCAA
CATGCTCATGCCCGAGCCCGCCCAGCGCTGGTTGGTGGGCTTCGTCTTATACACATTTCTCATG
GGCTTCCTGCTGCCTGTCGGGGCCATCTGCCTGTGTTACGTGCTCATCATTGCCAAGATGCGCA
TGGTGGCCCTCAAGGCCGGCTGGCAGCAGCGCAAGCGCTCAGAGCGCAAGATCACTCTAATGGT
GATGATGGTGGTGATGGTTTTTGTCATCTGCTGGATGCCTTTCTACGTGGTACAGCTAGTCAAC
GTGTTCGCCGAGCAAGACGACGCCACGGTGAGCCAGTTGTCTGTCATCCTCGGCTATGCCAATA
GCTGTGCCAACCCCATCCTCTACGGCTTCCTGTCGGACAACTTCAAGCGCTCTTTCCAGCGCAT
CCTGTGCCTCAGCTGGATGGATAACGCTGCGGAGGAGCCTGTTGACTACTACGCCACTGCCCTG
AAGAGTCGTGCCTACAGTGTGGAGGACTTCCAGCCTGAGAATCTGGAATCTGGAGGCGTTTTCC
GTAATGGCACCTGCGCTTCCAGGATCAGCACGCTTTGAGGCCGGACGCTAACCGGAGGGGGAGA
GTGGTCAGAAAGGTGGAGAGGGGAAGCAGGTGGGAGGGAATGATAGCCGCACACCAGGTGCTAT
GGGAGTAGTGCGTGACAGCGATGCAGCGCCCCTGTTTAGCAAAGCTATGTGACTAAGGTAAACG
GGAGAGATTTGAGAATGTTTTCGGGCCATCTGGTATTCTGAACTGTGTTCTCCAAACCCGATAA
TTTCCATCCTCCCTCCCAGTTCTGCTAGTACAAACTGCAAACTTAACGTCGCCAACTCCGTTTG
ACCCTTTCCCTCTCAAGCTGTTATTTCTGCTTCTTTAAACTGAGCCATCTTGTGTTTCTTTTGG
GCTGAGTCCCCACCTTGCGCTGAACCCCCTGCGCAGGTCCCCGGGCCAGACTCTTCAGAGCGGC
TACCAGACTGTCCCCAGTTACCGCTCCCCTTTTGCACAGCCTTACTGTCAAGTAAGCCCAGCTC
CAGGATGACCAGGCAACTGGTCTTTTCTACTCTCAAAGAAGGCACCATCTTCCCTTGGGCCCTT
TCTCTGCTTCACTGCATCCAGAGCAGAGCTGGGTGCTTAAGAAAAAGTCCTGTGCCCAGATGGC
CAGACTTGGTGTAGTCCCACCCATTCCCTCCTTTGGAGCACAAAAAGGAGCTAAGAGCCAGCAG
AAGGGCAAGTTTCTAAGATTCCTGGGCTGTGGTTGTGGGTGCCAGAGAAGCCACCCTCCCATAG
AGCTCAGGACCTGAGCACTAGGCTTGGAGGTCCCAGCTAGGGGAGCTCCCGGCTTGTGAATAAC
TTATGCACCCTGGTGTGTGAACCTGAATTGCACAGCAGTTCCCCTTGGAGGTCTCCCTAGAATA
ACAAAGGATTGGGTTGCCTGCTCCCTTTCCTAGTCCAGCTCCTGTTCCAGTGACAAACCGCAGA
GCCCTTGCCAAAGCTGGATGGCTAACTTCAGCTTGTCTGGTCCCTGACATTTTTTGCCTTTCAA
GCGGTGCCTAATAAGTTATTTCTTGTTTGACATATTTATTTATTTATTTATAGTGTTGAAAAAA
AAGTGTGTTTCCACTTTCTTTTTCTGTATTTGCCTAACAGGGCTGTTCTTGAGAATCCTCTGGC
AGGCACGTGGTGGTGTGGAGGTGTGGAGGGGAGCAGGGGTGGAGAAAGTTCTCTCACCCCAAGA
CTCCCTCAGAAGTTTCCCTCTTTTGCACTCCATTGGCCTTTTCTTGATCCTTCTTGGTTTTGCT
TGTGTCCAGTGAAGTTTGGAGATTTTAAAAATATATTTTTACTGTAGTTTTGTCTTGTTAAAAT
AAGTACATGGCAATTTGGTTTAACTTTTGTCAGTGTGGAGTGGAAGGCCTGAATCCCTGGCATC
CCAGAAAACACAGGGGAACAAATCACATGATCCGTGATGTATGTCTGTATATGTGCTGTCACAC
ACAAGTCACATATATACGTGTATATATATATCATATATGTACACACACATATAAAGGTAGATTT
GTCAATCTTGACAACTGTCACTAGTTCATGACAATTATAAGGACACCCACAATGTGTGACCTGA
GCTGTAGCACTCCAGCTGGGATCTGAGAAACGTCAGAGATTGGAGTCGCTGCTGAAGATGCTGC
TGCCTTTTTCTATCCCCTCAGAGGTGATTCTTACCCAGTAAGTCTAGTCACTTTTGTTGAGGAA
TGGAAGCGAAACAATTGTGTCTGCATTTACTGACTACCGTGGAAACCTGAACACGGAAGGACCC
ATCTCTTCACTTGTTGCATTTGCTGTGTTCCTGTGTATGCTCGTTTGTACATAGGGGCCACTGA
AAGGATATCTTGCTTGGTTGTTTAAGGAAGCCAGTGTATATCAGTGGTCTTAGAACAATGAACC
TGGGGTTCTCGGGTCCACAGTGACCTGACATCTAACCTGCAATGGTCGAATGCACTGTTGAAAA
TGGTGTTTTGTGTACATTTGCTTCAAGAACACATCCATGCTTTTCTAAAAGCAGGAACCAAGAG
TTAAACTGTCTCTTCTGTTTTGTTTAAATAAATGAACAAATATGCTTTTGATCATAAGTGAGAA
AGTTTAGATCTTTTCCTAAGAATAGTATATATATATATGTATATATATATACTTTTCTGTTAAT
TAGATTTTTTAACCGATAAGAAGAGTGAACTTTATAAACTGAAATCTCCATCATTATCATCTCG
ACAGGATAAAAATGTAGTGCTCTTACCCTGTAATAGTAACTGAATAAAAAGATGTATTATGCTG
TT

hide sequence

RefSeq Acc Id:

XM_006240115 ⟹ XP_006240177

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	81,567,237 - 81,571,759 (+)	NCBI
mRatBN7.2	6	75,832,292 - 75,836,806 (+)	NCBI
Rnor_6.0	6	79,252,914 - 79,258,611 (+)	NCBI
Rnor_5.0	6	88,783,414 - 88,787,997 (+)	NCBI

Sequence:

show sequence

TACCTTCCTCTCCAACTCACATTCCGCTTCAGGTAAGTGGTTTGTTCAGGTAAAGCAAGGCATT
AAATAGCCCCACTCCTATCAAGTCTGGAATTCCACTCTAACATTTTTTTCTCATGAATAATTCA
GCATCTGTTACACACACTCTTAGGGAGTCTGTGGTCATTGATTTTAATCTGACTGCCTCTGCCA
TCATGGACACCGCACGTGATTCTTTCTCTCCTAGCAGCACTGAGTTTGGGAGAGCGAAGAATCC
ATGTGTAGGCAATTTCTGAGAACAAGCAACAAGCCATTGTTGGATTGATGCTTTACTTTTAATG
CGGTGTCCAACTCTGTGCACTCTAGACTGTCTGGTAGGGACAGCTTCGGTAAATTTGGTTTTAA
ATTTACCTCCTCTTGGTGGAGATGTGAGAGGGAGACTGAGGAAGACAAGCAATTGTGAGCAGCC
CAGCTCCAGGGTGAGCACTGGACTGCAGCGGCCAGTCTTCCTGAGACTTGGCATGCTTCCTGCA
AAGACTTGCAGGGATTTCGTGGAAGGAAATTCCTTTCATGAAAAGGAATAGGTGGTTGAATCAT
TTAGCAGAGAGTAGCTGTAAGGCCAAAGAGACCCTAGGTTCAGAGTCCTGGGAACTCCCAAGGT
CCCTTAAAAATCAACATCCATTCTTTCTCAATCAAGAGCCTGTAGTTCCCAGACTTGGGATGGG
AACTGCAGGTCGATGAGCTTTGAGCCTGGGGCTTTAATAACTATATCTTAATGGTTTTAGCATT
TGGAACACAGAGGGGGTTATCCCTCAAGGCTCTACTATCCCTTAGTATTCCATAGGGGAAAGCT
TGAAAGTCTTGCCACTGTTTCCAGGCTTGATGACAGTCCATCAGTTGCTCAGCCAGCCACGCGT
GGATTAAGAGCTGTCGCGCCTGCCTATTCTGGCCTTGGCGCTCTCCACCTCCATCCCCCACCCC
GCCAACTCTCCCGGGTACAAAGTACAGCCGGGACGCGGCGCGGGAGCAGCTGTTCCAAGCCGCG
CAGCCTAATCTTTCCCCAGTGAACACCTACATGGATTTCCAATACCGCGCCTGGCAGGTTCCGG
AGGGAGTGCCAGCCTCCTCCTGAGCTCTCTGCCCCGCATTCTGACTTCTGCAGTGGATATCCCT
AGGGGAGGTGGGGGGGGGCAGGGCTCAGGGAATTACAAGCTTTGTTAGACAGTCGCAATGGTTC
CACTGAGTCCCCCTGAACACTCCCTGCTGCAGAGTGGAGGGCGATGGATGTTGTAACTCAGCAT
CCCTTAACACACCACTGTAGTCCTCCGTGCTCATAATGCTATTGGCTTAGGTCTGGTTTCCACC
GCTCAGTGTTTGCGTGGGCACTTGTGCAGCAGCCAGCCCCAAAGGGAGTTGGACCTCGCAAAAG
AACGTCAGAGCGCCGCCAGACCTCACAAGCACTTTGCAAGGGCCATCTGGAGACATCGATTTAG
GGACCCGACGACCTGAAATCTCCAGGTACAGTTTTGAAGAACTGGCAAGCAGGAAAGGAGTGTA
TCCAGGACCCCCAGAGCTGCAAGAGACAGCGCTCAAGCAAGCAGCCGCCGGGCGTTGCGCCAGA
CGGCCTCAGTTGGAGCCGCGCTCGCCACAGCTGCTGCGCGCTGCCGGGAGGCGCCAGGCGCCGG
TGAGCTGTGAGCTTGGAGCCTTGAGCCTAGGGAGGGCGCAGGCAGCAAGGGCGCAAGGTGAGCG
TCCCAACCGGCGGCCACACCGGCCCACTTCAGCTGGGATGTTCCCCAATGGCACCGCCCCCTCT
CCCACCTCTTCTCCCAGCTCCAGCCCAGGCGGCTGCGGGGAAGGAGTCTGCAGCAGGGGTCCCG
GGTCCGGCGCTGCGGACGGCATGGAAGAACCTGGACGAAACTCTTCCCAGAACGGGACTTTAAG
CGAGGGTCAGGGTAGCGCCATTCTCATCTCTTTCATCTACTCCGTGGTATGCTTGGTGGGACTG
TGTGGGAACTCCATGGTCATTTACGTGATCCTGCGCTACGCCAAGATGAAGACCGCAACCAACA
TCTACATTCTAAACCTGGCCATTGCTGATGAGCTGCTCATGCTCAGCGTGCCCTTTCTGGTCAC
TTCCACGCTGTTGCGCCACTGGCCCTTTGGCGCGCTACTTTGCCGCCTGGTGCTCAGCGTGGAT
GCAGTCAACATGTTCACCAGCATCTACTGTCTGACTGTGCTTAGTGTGGACCGCTATGTGGCTG
TGGTGCACCCGATCAAGGCAGCGCGCTACCGTCGGCCCACTGTGGCCAAAGTAGTGAACCTGGG
CGTGTGGGTGCTGTCGCTACTGGTTATCTTGCCCATCGTGGTCTTCTCACGCACCGCAGCCAAC
AGCGATGGCACGGTGGCCTGCAACATGCTCATGCCCGAGCCCGCCCAGCGCTGGTTGGTGGGCT
TCGTCTTATACACATTTCTCATGGGCTTCCTGCTGCCTGTCGGGGCCATCTGCCTGTGTTACGT
GCTCATCATTGCCAAGATGCGCATGGTGGCCCTCAAGGCCGGCTGGCAGCAGCGCAAGCGCTCA
GAGCGCAAGATCACTCTAATGGTGATGATGGTGGTGATGGTTTTTGTCATCTGCTGGATGCCTT
TCTACGTGGTACAGCTAGTCAACGTGTTCGCCGAGCAAGACGACGCCACGGTGAGCCAGTTGTC
TGTCATCCTCGGCTATGCCAATAGCTGTGCCAACCCCATCCTCTACGGCTTCCTGTCGGACAAC
TTCAAGCGCTCTTTCCAGCGCATCCTGTGCCTCAGCTGGATGGATAACGCTGCGGAGGAGCCTG
TTGACTACTACGCCACTGCCCTGAAGAGTCGTGCCTACAGTGTGGAGGACTTCCAGCCTGAGAA
TCTGGAATCTGGAGGCGTTTTCCGTAATGGCACCTGCGCTTCCAGGATCAGCACGCTTTGAGGC
CGGACGCTAACCGGAGGGGGAGAGTGGTCAGAAAGGTGGAGAGGGGAAGCAGGTGGGAGGGAAT
GATAGCCGCACACCAGGTGCTATGGGAGTAGTGCGTGACAGCGATGCAGCGCCCCTGTTTAGCA
AAGCTATGTGACTAAGGTAAACGGGAGAGATTTGAGAATGTTTTCGGGCCATCTGGTATTCTGA
ACTGTGTTCTCCAAACCCGATAATTTCCATCCTCCCTCCCAGTTCTGCTAGTACAAACTGCAAA
CTTAACGTCGCCAACTCCGTTTGACCCTTTCCCTCTCAAGCTGTTATTTCTGCTTCTTTAAACT
GAGCCATCTTGTGTTTCTTTTGGGCTGAGTCCCCACCTTGCGCTGAACCCCCTGCGCAGGTCCC
CGGGCCAGACTCTTCAGAGCGGCTACCAGACTGTCCCCAGTTACCGCTCCCCTTTTGCACAGCC
TTACTGTCAAGTAAGCCCAGCTCCAGGATGACCAGGCAACTGGTCTTTTCTACTCTCAAAGAAG
GCACCATCTTCCCTTGGGCCCTTTCTCTGCTTCACTGCATCCAGAGCAGAGCTGGGTGCTTAAG
AAAAAGTCCTGTGCCCAGATGGCCAGACTTGGTGTAGTCCCACCCATTCCCTCCTTTGGAGCAC
AAAAAGGAGCTAAGAGCCAGCAGAAGGGCAAGTTTCTAAGATTCCTGGGCTGTGGTTGTGGGTG
CCAGAGAAGCCACCCTCCCATAGAGCTCAGGACCTGAGCACTAGGCTTGGAGGTCCCAGCTAGG
GGAGCTCCCGGCTTGTGAATAACTTATGCACCCTGGTGTGTGAACCTGAATTGCACAGCAGTTC
CCCTTGGAGGTCTCCCTAGAATAACAAAGGATTGGGTTGCCTGCTCCCTTTCCTAGTCCAGCTC
CTGTTCCAGTGACAAACCGCAGAGCCCTTGCCAAAGCTGGATGGCTAACTTCAGCTTGTCTGGT
CCCTGACATTTTTTGCCTTTCAAGCGGTGCCTAATAAGTTATTTCTTGTTTGACATATTTATTT
ATTTATTTATAGTGTTGAAAAAAAAGTGTGTTTCCACTTTCTTTTTCTGTATTTGCCTAACAGG
GCTGTTCTTGAGAATCCTCTGGCAGGCACGTGGTGGTGTGGAGGTGTGGAGGGGAGCAGGGGTG
GAGAAAGTTCTCTCACCCCAAGACTCCCTCAGAAGTTTCCCTCTTTTGCACTCCATTGGCCTTT
TCTTGATCCTTCTTGGTTTTGCTTGTGTCCAGTGAAGTTTGGAGATTTTAAAAATATATTTTTA
CTGTAGTTTTGTCTTGTTAAAATAAGTACATGGCAATTTGGTTTAACTTTTGTCAGTGTGGAGT
GGAAGGCCTGAATCCCTGGCATCCCAGAAAACACAGGGGAACAAATCACATGATCCGTGATGTA
TGTCTGTATATGTGCTGTCACACACAAGTCACATATATACGTGTATATATATATCATATATGTA
CACACACATATAAAGGTAGATTTGTCAATCTTGACAACTGTCACTAGTTCATGACAATTATAAG
GACACCCACAATGTGTGACCTGAGCTGTAGCACTCCAGCTGGGATCTGAGAAACGTCAGAGATT
GGAGTCGCTGCTGAAGATGCTGCTGCCTTTTTCTATCCCCTCAGAGGTGATTCTTACCCAGTAA
GTCTAGTCACTTTTGTTGAGGAATGGAAGCGAAACAATTGTGTCTGCATTTACTGACTACCGTG
GAAACCTGAACACGGAAGGACCCATCTCTTCACTTGTTGCATTTGCTGTGTTCCTGTGTATGCT
CGTTTGTACATAGGGGCCACTGAAAGGATATCTTGCTTGGTTGTTTAAGGAAGCCAGTGTATAT
CAGTGGTCTTAGAACAATGAACCTGGGGTTCTCGGGTCCACAGTGACCTGACATCTAACCTGCA
ATGGTCGAATGCACTGTTGAAAATGGTGTTTTGTGTACATTTGCTTCAAGAACACATCCATGCT
TTTCTAAAAGCAGGAACCAAGAGTTAAACTGTCTCTTCTGTTTTGTTTAAATAAATGAACAAAT
ATGCTTTTGATCATAAGTGAGAAAGTTTAGATCTTTTCCTAAGAATAGTATATATATATATGTA
TATATATATACTTTTCTGTTAATTAGATTTTTTAACCGATAAGAAGAGTGAACTTTATAAACTG
AAATCTCCATCATTATCATCTCGACAGGATAAAAATGTAGTGCTCTTACCCTGTAATAGTAACT
GAATAAAAAGATGTATTATGCTGTT

hide sequence

RefSeq Acc Id:

XM_063261554 ⟹ XP_063117624

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	81,567,237 - 81,571,759 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_036851	(Get FASTA)	NCBI Sequence Viewer
	XP_006240177	(Get FASTA)	NCBI Sequence Viewer
	XP_063117624	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL76096	(Get FASTA)	NCBI Sequence Viewer
	CAA44193	(Get FASTA)	NCBI Sequence Viewer
	EDM03458	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067355
	ENSRNOP00000067355.1
	ENSRNOP00055019482
	ENSRNOP00060028642
	ENSRNOP00065005333
GenBank Protein	P28646	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_036851 ⟸ NM_012719

- UniProtKB:

P28646 (UniProtKB/Swiss-Prot), A6HBQ4 (UniProtKB/TrEMBL), Q7TT86 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFI
YSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGAL
LCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPI
VVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALK
AGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANP
ILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTC
ASRISTL

hide sequence

RefSeq Acc Id:	XP_006240177 ⟸ XM_006240115
- Peptide Label:	isoform X1
- UniProtKB:	P28646 (UniProtKB/Swiss-Prot), A6HBQ4 (UniProtKB/TrEMBL), Q7TT86 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFI YSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGAL LCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPI VVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALK AGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANP ILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTC ASRISTL hide sequence

RefSeq Acc Id:

ENSRNOP00000067355 ⟸ ENSRNOT00000073970

RefSeq Acc Id:	XP_063117624 ⟸ XM_063261554
- Peptide Label:	isoform X1

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P28646-F1-model_v2	AlphaFold	P28646	1-391	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3762	AgrOrtholog
BioCyc Gene	G2FUF-37401	BioCyc
Ensembl Genes	ENSRNOG00000048145	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055013885	UniProtKB/Swiss-Prot
	ENSRNOG00060020151	UniProtKB/Swiss-Prot
	ENSRNOG00065005236	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000073970	ENTREZGENE
	ENSRNOT00000073970.3	UniProtKB/Swiss-Prot
	ENSRNOT00055023884	UniProtKB/Swiss-Prot
	ENSRNOT00060034887	UniProtKB/Swiss-Prot
	ENSRNOT00065007697	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Somatstn_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Somatstn_rcpt_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25033	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	25033	ENTREZGENE
PANTHER	NEUROPEPTIDES RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SOMATOSTATIN RECEPTOR TYPE 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Sstr1	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SOMATOSTATNR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SOMATOSTTN1R	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000048145	RatGTEx
	ENSRNOG00055013885	RatGTEx
	ENSRNOG00060020151	RatGTEx
	ENSRNOG00065005236	RatGTEx
SMART	7TM_GPCR_Srsx	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC202357
UniProt	A6HBQ4	ENTREZGENE, UniProtKB/TrEMBL
	P28646	ENTREZGENE
	Q7TT86	ENTREZGENE, UniProtKB/TrEMBL
	SSR1_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2003-04-09	Sstr1	somatostatin receptor 1		Somatostatin receptor subtype 1	Symbol and Name updated	629477	APPROVED
2002-06-10	Sstr1	Somatostatin receptor subtype 1			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	preferentially expressed in brain, particularly in cerebral cortex and hippocampus	730160
gene_physical_interaction	binds somatostatin-14	730160
gene_protein	391 amino acids with seven potential transmembrane domains	730160

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations