Kidm55 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Kidm55 (Kidney mass QTL 55) Rattus norvegicus

Symbol: Kidm55
Name: Kidney mass QTL 55
RGD ID: 10450862
Trait: kidney mass   (VT:0002707)    
Measurement Type: kidney weight   (CMO:0000081)    
LOD Score: 4.9
P Value: Not Available
Variance: 36.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2770,840,118 - 72,474,897RGD_MAPPER_PIPELINE
Rnor_6.0778,758,303 - 80,297,776RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0778,786,126 - 80,323,758RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4775,357,125 - 77,004,148RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SHR.BN-(D8Mit5-D8Mgh6)/Ipcv BXH2/Cub 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait
kidney mass  (IDA)

Rat Strain

References

References - curated
1. Hodulova M, etal., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
68376Dpysdihydropyrimidinase77876991878847941Rat
9298404LOC103692892uncharacterized LOC10369289277883880778863932Rat
1304943Lrp12LDL receptor related protein 1277885978478930850Rat
1565735RGD1565735similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12)77899119778992177Rat
9196150LOC103692893uncharacterized LOC10369289377914873979165245Rat
9421126LOC103692894uncharacterized LOC10369289477917833779192638Rat
11420341LOC108351484uncharacterized LOC10835148477935677279400406Rat
11463877LOC108351485uncharacterized LOC10835148577945938079485461Rat
1306021Zfpm2zinc finger protein, multitype 277947127779964405Rat
7655393LOC102556196uncharacterized LOC10255619678019450180244543Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
42833D7Rat20622977875830378758526Ratregion
41558D7Rat14212577962911879629245Ratregion
60579D7Got5218778029759080297776Ratregion
1631587D7Got23418677974545079745635Ratregion
1634664D7Got22222077909154079091865Ratregion
1634664D7Got22222077909154079091758Ratregion
5073880RH13769216977877006378770231Ratregion
5061092AW53222915877964643179646589Ratregion
5504550PMC303372P148577996360479964088Ratregion
5500230AI84882913977885985578859993Ratregion
Position Markers

Flank 1: (D7Rat206)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2770,840,118 - 70,840,342 (+)MAPPER
Rnor_6.0778,758,303 - 78,758,526NCBI
Rnor_5.0778,786,126 - 78,786,349UniSTS
RGSC_v3.4775,357,125 - 75,357,349RGD
RGSC_v3.4775,357,126 - 75,357,349UniSTS
RGSC_v3.1775,377,855 - 75,378,079RGD
Celera767,893,790 - 67,894,013UniSTS
SHRSP x BN Map745.53RGD
SHRSP x BN Map745.53UniSTS
Flank 2: (D7Got52)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2772,474,710 - 72,474,897 (+)MAPPER
Rnor_6.0780,297,590 - 80,297,776NCBI
Rnor_5.0780,323,572 - 80,323,758UniSTS
RGSC_v3.4777,003,961 - 77,004,147RGD
RGSC_v3.4777,003,962 - 77,004,148UniSTS
RGSC_v3.1777,024,691 - 77,024,877RGD
Celera769,493,553 - 69,493,739UniSTS
RH 3.4 Map7633.3RGD
RH 3.4 Map7633.3UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)72920071124838025Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)712328467106995532Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72536563393155402Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)73586772980867729Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)73586772993155402Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73854770683547706Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)74087268285872682Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)74087268285872682Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74530157390301573Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)748118835128611831Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)75025210395252103Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)750704769128085642Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)75079381895793818Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)751251919118477612Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)751251919145729302Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)751252005111589099Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)75320034498200344Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)75425951299259512Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)755072862123602998Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)755072862123602998Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)755072862123602998Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)755495689100495689Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)755495689100495689Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)755495689100495689Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)755495689100495689Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)755495689100495689Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)755495689100495689Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)755495689100495689Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)761047589113228378Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)768518460113518460Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)769399586111043530Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)769399586111043530Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)770421228115421228Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)771448715145729302Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)777428105127748511Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)777428234122421148Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)77875830380297776Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)77875830380297776Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general 9 genes are present in this region  
qtl_general number of animals used: 8-13 males, 4 month old from 15 PXO recombinant inbred strains 10402111
qtl_general software used: STATISTICA 10 CZ; ANOVA 10402111
qtl_general confidence interval: 74,492-76,763 Kbp 10402111
qtl_general measurement method: 4 month old male rats were fed high-sucrose diet for 1 week; the rats were sacrificed and kidney weight taken