Naga (alpha-N-acetylgalactosaminidase) - Rat Genome Database

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Gene: Naga (alpha-N-acetylgalactosaminidase) Rattus norvegicus
Analyze
Symbol: Naga
Name: alpha-N-acetylgalactosaminidase
RGD ID: 1306025
Description: Predicted to enable alpha-N-acetylgalactosaminidase activity; alpha-galactosidase activity; and protein homodimerization activity. Predicted to be involved in several processes, including glycolipid catabolic process; glycoside catabolic process; and oligosaccharide metabolic process. Predicted to be located in lysosome and membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Kanzaki disease; Schindler disease type 1; angiokeratoma; and neuroaxonal dystrophy. Orthologous to human NAGA (alpha-N-acetylgalactosaminidase); PARTICIPATES IN globoside metabolic pathway; INTERACTS WITH (+)-schisandrin B; 4,4'-sulfonyldiphenol; aconitine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha-galactosidase B; LOC315165; N-acetyl galactosaminidase, alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,726,438 - 115,735,494 (-)NCBIGRCr8
mRatBN7.27113,846,358 - 113,855,430 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,846,374 - 113,855,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,602,301 - 115,610,513 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,825,818 - 117,834,032 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,795,268 - 117,803,480 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,563,047 - 123,572,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,563,059 - 123,572,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,547,766 - 123,556,889 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,706,129 - 120,714,429 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17120,740,375 - 120,748,659 (-)NCBI
Celera7110,161,450 - 110,169,578 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRatangiokeratoma  ISONAGA (Homo sapiens)1600558Kanzaki Disease more ...RGD 
NagaRatCOVID-19  ISONAGA (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
NagaRatneuroaxonal dystrophy  ISONAGA (Homo sapiens)1600557Schindler disease more ...RGD 
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRatadenylosuccinase lyase deficiency  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Adenylosuccinate lyase deficiencyClinVarPMID:28492532
NagaRatcommon variable immunodeficiency 4  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency more ...ClinVarPMID:19666484 and PMID:28492532
NagaRatDevelopmental Delay with Variable Intellectual Impairment and Behavioral Abnormalities  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental delay with variable intellectual impairment and behavioral abnormalitiesClinVarPMID:30819258 and PMID:31690835
NagaRatfetal akinesia deformation sequence syndrome 1  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Fetal akinesia deformation sequence 1ClinVarPMID:25741868 and PMID:31680123
NagaRatgenetic disease  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:11251574 more ...
NagaRatintellectual disability  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
NagaRatKanzaki disease  ISONAGA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11251574 more ...
NagaRatSchindler disease  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Alpha-N-acetylgalactosaminidase deficiencyClinVarPMID:11251574 more ...
NagaRatSchindler disease type 1  ISONAGA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11251574 more ...
NagaRatSchindler disease type 3  ISONAGA (Homo sapiens)8554872ClinVar Annotator: match by term: Alpha-N-acetylgalactosaminidase deficiency type 3ClinVarPMID:11251574 more ...
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRatneuroaxonal dystrophy  ISONAGA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:2243144
NagaRatSchindler disease type 1  ISONAGA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:2243144 and PMID:19683538
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRatKanzaki disease  ISONAGA (Homo sapiens)7240710 OMIM 
NagaRatSchindler disease type 1  ISONAGA (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRat(+)-catechin multiple interactionsISONAGA (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of NAGA mRNACTDPMID:24763279
NagaRat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NAGA mRNA]CTDPMID:31150632
NagaRat17alpha-ethynylestradiol increases expressionISONaga (Mus musculus)6480464Ethinyl Estradiol results in increased expression of NAGA mRNACTDPMID:17942748
NagaRat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISONAGA (Homo sapiens)64804642 more ...CTDPMID:31675489
NagaRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONaga (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NAGA mRNACTDPMID:21570461
NagaRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISONaga (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of NAGA mRNACTDPMID:33956508
NagaRat3,3',5,5'-tetrabromobisphenol A decreases expressionISONAGA (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of NAGA proteinCTDPMID:31675489
NagaRat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NAGA mRNACTDPMID:36041667
NagaRataconitine decreases expressionEXP 6480464Aconitine results in decreased expression of NAGA proteinCTDPMID:33236894
NagaRatacrylamide decreases expressionISONAGA (Homo sapiens)6480464Acrylamide results in decreased expression of NAGA mRNACTDPMID:32763439
NagaRataflatoxin B1 increases methylationISONAGA (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of NAGA intronCTDPMID:30157460
NagaRatall-trans-retinoic acid increases expressionISONAGA (Homo sapiens)6480464Tretinoin results in increased expression of NAGA mRNACTDPMID:33167477
NagaRatantirheumatic drug decreases expressionISONAGA (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of NAGA mRNACTDPMID:24449571
NagaRataristolochic acid A decreases expressionISONAGA (Homo sapiens)6480464aristolochic acid I results in decreased expression of NAGA mRNACTDPMID:33212167
NagaRatarsane multiple interactionsISONAGA (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NAGA mRNACTDPMID:39836092
NagaRatarsenic atom multiple interactionsISONAGA (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NAGA mRNACTDPMID:39836092
NagaRatbenzo[a]pyrene affects methylationISONAGA (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of NAGA exonCTDPMID:27901495
NagaRatbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of NAGA mRNACTDPMID:25181051
NagaRatbisphenol A increases expressionISONAGA (Homo sapiens)6480464bisphenol A results in increased expression of NAGA proteinCTDPMID:34186270 and PMID:37567409
NagaRatbisphenol A affects expressionISONaga (Mus musculus)6480464bisphenol A affects the expression of NAGA mRNACTDPMID:35341816

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRatbiological_process  ND 15984073/2007: no relevant rat dataRGD 
NagaRatcarbohydrate catabolic process involved_inISSUniProtKB:P170501600115GO_REF:0000024UniProtGO_REF:0000024
NagaRatcarbohydrate catabolic process involved_inISONAGA (Homo sapiens)1624291 PMID:19683538RGDPMID:19683538
NagaRatcarbohydrate catabolic process involved_inIEAUniProtKB:P17050 and ensembl:ENSP000003796801600115GO_REF:0000107EnsemblGO_REF:0000107
NagaRatcarbohydrate metabolic process involved_inIEAInterPro:IPR000111 and InterPro:IPR0022411600115GO_REF:0000002InterProGO_REF:0000002
NagaRatglycolipid catabolic process involved_inISSUniProtKB:P170501600115GO_REF:0000024UniProtGO_REF:0000024
NagaRatglycolipid catabolic process involved_inISONAGA (Homo sapiens)1624291 PMID:9741689RGDPMID:9741689
NagaRatglycolipid catabolic process involved_inIEAUniProtKB:P17050 and ensembl:ENSP000003796801600115GO_REF:0000107EnsemblGO_REF:0000107
NagaRatglycoside catabolic process involved_inIBAPANTHER:PTN000155295 and WB:WBGene000110951600115GO_REF:0000033GO_CentralGO_REF:0000033
NagaRatlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
NagaRatoligosaccharide metabolic process involved_inIBAPANTHER:PTN000155295 and UniProtKB:P062801600115GO_REF:0000033GO_CentralGO_REF:0000033
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRatcytoplasm is_active_inIBAMGI:1347344 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
NagaRatlysosome located_inIEAUniProtKB-SubCell:SL-01581600115GO_REF:0000044UniProtGO_REF:0000044
NagaRatlysosome located_inIEAUniProtKB-KW:KW-04581600115GO_REF:0000043UniProtGO_REF:0000043
NagaRatmembrane located_inIEAGO:00193771600115GO_REF:0000108GOCGO_REF:0000108

Molecular Function
1 to 10 of 10 rows

  
Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
NagaRatalpha-galactosidase activity enablesIBAMGI:1347344 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
NagaRatalpha-N-acetylgalactosaminidase activity enablesISSUniProtKB:P170501600115GO_REF:0000024UniProtGO_REF:0000024
NagaRatalpha-N-acetylgalactosaminidase activity enablesIEAEC:3.2.1.491600115GO_REF:0000003UniProtGO_REF:0000003
NagaRatalpha-N-acetylgalactosaminidase activity enablesIEAUniProtKB:P17050 and ensembl:ENSP000003796801600115GO_REF:0000107EnsemblGO_REF:0000107
NagaRatalpha-N-acetylgalactosaminidase activity enablesISONAGA (Homo sapiens)1624291 PMID:19683538RGDPMID:19683538
NagaRathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
NagaRathydrolase activity, acting on glycosyl bonds enablesIEAUniProtKB-KW:KW-03261600115GO_REF:0000043UniProtGO_REF:0000043
NagaRathydrolase activity, hydrolyzing O-glycosyl compounds enablesIEAInterPro:IPR000111 and InterPro:IPR0022411600115GO_REF:0000002InterProGO_REF:0000002
NagaRatprotein homodimerization activity enablesISONAGA (Homo sapiens)1624291UniProtKB:P17050 and PMID:19683538RGDPMID:19683538
NagaRatprotein homodimerization activity enablesIEAUniProtKB:P17050 and ensembl:ENSP000003796801600115GO_REF:0000107EnsemblGO_REF:0000107
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Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NagaRatgloboside metabolic pathway  IEA 6907045 KEGGrno:00603

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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Schindler disease: the molecular lesion in the alpha-N-acetylgalactosaminidase gene that causes an infantile neuroaxonal dystrophy. Wang AM, etal., J Clin Invest. 1990 Nov;86(5):1752-6.
11. The molecular lesion in the alpha-N-acetylgalactosaminidase gene that causes angiokeratoma corporis diffusum with glycopeptiduria. Wang AM, etal., J Clin Invest. 1994 Aug;94(2):839-45.
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PMID:9741689   PMID:12477932   PMID:15489334   PMID:19683538   PMID:23376485   PMID:23533145  



Naga
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,726,438 - 115,735,494 (-)NCBIGRCr8
mRatBN7.27113,846,358 - 113,855,430 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,846,374 - 113,855,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,602,301 - 115,610,513 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,825,818 - 117,834,032 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,795,268 - 117,803,480 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,563,047 - 123,572,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,563,059 - 123,572,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,547,766 - 123,556,889 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,706,129 - 120,714,429 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17120,740,375 - 120,748,659 (-)NCBI
Celera7110,161,450 - 110,169,578 (-)NCBICelera
Cytogenetic Map7q34NCBI
NAGA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382242,058,334 - 42,070,842 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2242,058,334 - 42,070,842 (-)EnsemblGRCh38hg38GRCh38
GRCh372242,454,338 - 42,466,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,784,331 - 40,796,719 (-)NCBINCBI36Build 36hg18NCBI36
Build 342240,778,884 - 40,791,273NCBI
Celera2226,260,520 - 26,273,049 (-)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2225,420,503 - 25,433,033 (-)NCBIHuRef
CHM1_12242,414,453 - 42,426,959 (-)NCBICHM1_1
T2T-CHM13v2.02242,537,918 - 42,550,425 (-)NCBIT2T-CHM13v2.0
Naga
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391582,213,746 - 82,222,983 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1582,213,733 - 82,223,126 (-)EnsemblGRCm39 Ensembl
GRCm381582,329,532 - 82,338,884 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,329,532 - 82,338,925 (-)EnsemblGRCm38mm10GRCm38
MGSCv371582,159,962 - 82,169,256 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361582,157,307 - 82,166,570 (-)NCBIMGSCv36mm8
Celera1584,453,684 - 84,462,981 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.56NCBI
Naga
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541327,461,998 - 27,472,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541327,463,931 - 27,472,273 (-)NCBIChiLan1.0ChiLan1.0
NAGA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22351,888,980 - 51,901,548 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12254,588,144 - 54,600,693 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02222,951,723 - 22,964,278 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12241,035,622 - 41,046,431 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2241,035,622 - 41,046,431 (-)Ensemblpanpan1.1panPan2
NAGA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,303,950 - 23,312,409 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,304,354 - 23,396,068 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,236,291 - 23,248,260 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,046,730 - 24,058,681 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,048,856 - 24,140,741 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11023,764,333 - 23,776,295 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,085,173 - 24,097,124 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,259,163 - 24,271,114 (+)NCBIUU_Cfam_GSD_1.0
Naga
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049456,924,320 - 6,938,883 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493671837,135 - 48,893 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493671831,946 - 55,822 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAGA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl56,571,020 - 6,588,055 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.156,580,141 - 6,587,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.253,969,705 - 3,986,467 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAGA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,589,133 - 24,607,753 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1924,592,409 - 24,607,682 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045100,787,749 - 100,800,152 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Naga
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247526,675,255 - 6,692,231 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247526,682,272 - 6,689,491 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Naga
42 total Variants

Predicted Target Of
Summary Value
Count of predictions:282
Count of miRNA genes:161
Interacting mature miRNAs:186
Transcripts:ENSRNOT00000068020
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000068020   ⟹   ENSRNOP00000060590
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,846,374 - 113,855,315 (-)Ensembl
Rnor_6.0 Ensembl7123,563,059 - 123,572,082 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097900   ⟹   ENSRNOP00000096846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,846,521 - 113,855,287 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107846   ⟹   ENSRNOP00000089333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,851,035 - 113,855,315 (-)Ensembl
RefSeq Acc Id: NM_001012120   ⟹   NP_001012120
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,726,601 - 115,734,818 (-)NCBI
mRatBN7.27113,846,521 - 113,854,738 (-)NCBI
Rnor_6.07123,563,203 - 123,571,420 (-)NCBI
Rnor_5.07123,547,766 - 123,556,889 (-)NCBI
RGSC_v3.47120,706,129 - 120,714,429 (-)RGD
Celera7110,161,450 - 110,169,578 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242087   ⟹   XP_006242149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,726,438 - 115,735,437 (-)NCBI
mRatBN7.27113,846,358 - 113,855,391 (-)NCBI
Rnor_6.07123,563,047 - 123,572,060 (-)NCBI
Rnor_5.07123,547,766 - 123,556,889 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242088   ⟹   XP_006242150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,726,438 - 115,735,494 (-)NCBI
mRatBN7.27113,846,358 - 113,855,430 (-)NCBI
Rnor_6.07123,563,047 - 123,572,074 (-)NCBI
Rnor_5.07123,547,766 - 123,556,889 (-)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001012120 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242149 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242150 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH82084 (Get FASTA)   NCBI Sequence Viewer  
  EDM15661 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000060590
  ENSRNOP00000060590.1
  ENSRNOP00000096846
GenBank Protein Q66H12 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_001012120   ⟸   NM_001012120
- Peptide Label: precursor
- UniProtKB: Q66H12 (UniProtKB/Swiss-Prot),   A6HT60 (UniProtKB/TrEMBL),   A0A8I6B4W8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242150   ⟸   XM_006242088
- Peptide Label: isoform X1
- UniProtKB: Q66H12 (UniProtKB/Swiss-Prot),   A6HT60 (UniProtKB/TrEMBL),   A0A8I6B4W8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242149   ⟸   XM_006242087
- Peptide Label: isoform X1
- UniProtKB: Q66H12 (UniProtKB/Swiss-Prot),   A6HT60 (UniProtKB/TrEMBL),   A0A8I6B4W8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060590   ⟸   ENSRNOT00000068020
Ensembl Acc Id: ENSRNOP00000089333   ⟸   ENSRNOT00000107846
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H12-F1-model_v2 AlphaFold Q66H12 1-415 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695532
Promoter ID:EPDNEW_R6057
Type:initiation region
Name:Naga_1
Description:alpha-N-acetylgalactosaminidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07123,571,970 - 123,572,030EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-32630 BioCyc
Ensembl Genes ENSRNOG00000008064 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000068020 ENTREZGENE
  ENSRNOT00000068020.3 UniProtKB/Swiss-Prot
  ENSRNOT00000097900 ENTREZGENE
Gene3D-CATH 2.60.40.1180 UniProtKB/Swiss-Prot
  3.20.20.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7133636 IMAGE-MGC_LOAD
InterPro Aldolase_TIM UniProtKB/Swiss-Prot
  Glyco_hydro_27 UniProtKB/Swiss-Prot
  Glyco_hydro_27/36_CS UniProtKB/Swiss-Prot
  Glyco_hydro_b UniProtKB/Swiss-Prot
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot
  Melibiase/NAGA_C UniProtKB/Swiss-Prot
KEGG Report rno:315165 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95262 IMAGE-MGC_LOAD
NCBI Gene 315165 ENTREZGENE
PANTHER ALPHA-N-ACETYLGALACTOSAMINIDASE UniProtKB/Swiss-Prot
  PTHR11452 UniProtKB/Swiss-Prot
Pfam Melibiase_2 UniProtKB/Swiss-Prot
  Melibiase_2_C UniProtKB/Swiss-Prot
PhenoGen Naga PhenoGen
PRINTS GLHYDRLASE27 UniProtKB/Swiss-Prot
PROSITE ALPHA_GALACTOSIDASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008064 RatGTEx
Superfamily-SCOP Glycosyl hydrolase domain UniProtKB/Swiss-Prot
  SSF51445 UniProtKB/Swiss-Prot
UniProt A0A8I6ABQ1_RAT UniProtKB/TrEMBL
  A0A8I6B4W8 ENTREZGENE, UniProtKB/TrEMBL
  A6HT60 ENTREZGENE, UniProtKB/TrEMBL
  NAGAB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-18 Naga  alpha-N-acetylgalactosaminidase  Naga  N-acetyl galactosaminidase, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Naga  N-acetyl galactosaminidase, alpha  Naga_predicted  N-acetyl galactosaminidase, alpha (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Naga_predicted  N-acetyl galactosaminidase, alpha (predicted)      Symbol and Name status set to approved 70820 APPROVED