Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SLC8A2 (solute carrier family 8 member A2) Homo sapiens
Analyze
Symbol: SLC8A2
Name: solute carrier family 8 member A2
Description: Predicted to have calcium:sodium antiporter activity. Predicted to be involved in several processes, including inorganic cation transmembrane transport; learning or memory; and regulation of synaptic plasticity. Predicted to localize to the integral component of plasma membrane. Biomarker of Alzheimer's disease; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 5-aza-2'-deoxycytidine; antirheumatic drug; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Na(+)/Ca(2+)-exchange protein 2; Na+/Ca2+-exchanging protein Nac2; NCX2; sodium-calcium exchanger 2; sodium/calcium exchanger 2; solute carrier family 8 (sodium-calcium exchanger), member 2; solute carrier family 8 (sodium/calcium exchanger), member 2; solute carrier family 8 member 2
Orthologs:
Mus musculus (house mouse) : Slc8a2 (solute carrier family 8 (sodium/calcium exchanger), member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc8a2 (solute carrier family 8 member A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc8a2 (solute carrier family 8 member A2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC8A2 (solute carrier family 8 member A2)
Canis lupus familiaris (dog) : SLC8A2 (solute carrier family 8 member A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc8a2 (solute carrier family 8 member A2)
Sus scrofa (pig) : SLC8A2 (solute carrier family 8 member A2)
Chlorocebus sabaeus (green monkey) : SLC8A2 (solute carrier family 8 member A2)
Heterocephalus glaber (naked mole-rat) : Slc8a2 (solute carrier family 8 member A2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1947,428,017 - 47,471,893 (-)Ensembl
GRCh381947,428,017 - 47,471,893 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371947,931,274 - 47,975,307 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361952,623,735 - 52,666,934 (-)NCBINCBI36hg18NCBI36
Build 341952,623,734 - 52,666,934NCBI
Celera1944,737,047 - 44,781,071 (-)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1944,359,692 - 44,403,467 (-)NCBIHuRef
CHM1_11947,933,461 - 47,977,474 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC8A2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731774
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.