Hdac7 (histone deacetylase 7) - Rat Genome Database

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Gene: Hdac7 (histone deacetylase 7) Rattus norvegicus
Analyze
Symbol: Hdac7
Name: histone deacetylase 7
RGD ID: 619982
Description: Predicted to enable several functions, including 14-3-3 protein binding activity; protein kinase C binding activity; and transcription corepressor activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of neuron death; and neuron apoptotic process. Predicted to be located in cytosol and nucleus. Predicted to be part of histone deacetylase complex. Orthologous to human HDAC7 (histone deacetylase 7); PARTICIPATES IN histone modification pathway; hypoxia inducible factor pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HD7; HD7a; Hdac7a; histone deacetylase 7A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27128,923,918 - 128,962,025 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7128,923,920 - 128,962,072 (-)Ensembl
Rnor_6.07139,280,396 - 139,319,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7139,281,187 - 139,318,455 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07139,471,977 - 139,510,581 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,501,738 - 136,523,073 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17136,593,467 - 136,597,288 (-)NCBI
Celera7125,415,230 - 125,435,773 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
cytoplasm  (ISO,ISS,TAS)
cytosol  (ISO)
histone deacetylase complex  (IEA,TAS)
nucleus  (ISO,ISS,TAS)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:16109736   PMID:16260608   PMID:16873063   PMID:16980613   PMID:17360565   PMID:17997710   PMID:19351956   PMID:20188095   PMID:20590529   PMID:25411248   PMID:25916381   PMID:30538141  
PMID:32106109  


Genomics

Comparative Map Data
Hdac7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27128,923,918 - 128,962,025 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7128,923,920 - 128,962,072 (-)Ensembl
Rnor_6.07139,280,396 - 139,319,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7139,281,187 - 139,318,455 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07139,471,977 - 139,510,581 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,501,738 - 136,523,073 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17136,593,467 - 136,597,288 (-)NCBI
Celera7125,415,230 - 125,435,773 (-)NCBICelera
Cytogenetic Map7q36NCBI
HDAC7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,782,722 - 47,821,344 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1247,782,722 - 47,833,132 (-)EnsemblGRCh38hg38GRCh38
GRCh371248,176,505 - 48,213,686 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,462,772 - 46,499,924 (-)NCBINCBI36hg18NCBI36
Build 341246,462,775 - 46,479,190NCBI
Celera1246,974,055 - 47,011,314 (-)NCBI
Cytogenetic Map12q13.11NCBI
HuRef1245,207,665 - 45,244,811 (-)NCBIHuRef
CHM1_11248,142,408 - 48,179,666 (-)NCBICHM1_1
Hdac7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,690,542 - 97,742,383 (-)NCBIGRCm39mm39
GRCm39 Ensembl1597,690,545 - 97,742,383 (-)Ensembl
GRCm381597,792,661 - 97,844,502 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,792,664 - 97,844,502 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,623,112 - 97,662,102 (-)NCBIGRCm37mm9NCBIm37
MGSCv361597,620,715 - 97,659,705 (-)NCBImm8
Celera1599,920,309 - 99,939,192 (-)NCBICelera
Cytogenetic Map15F1NCBI
Hdac7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555006,693,668 - 6,709,864 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555006,692,656 - 6,707,453 (-)NCBIChiLan1.0ChiLan1.0
HDAC7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11241,788,202 - 41,825,123 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1241,789,367 - 41,825,123 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01240,913,301 - 40,950,542 (+)NCBIMhudiblu_PPA_v0panPan3
HDAC7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,941,287 - 6,968,370 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,929,829 - 6,979,317 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2739,338,114 - 39,375,845 (-)NCBI
ROS_Cfam_1.0276,998,714 - 7,036,476 (+)NCBI
ROS_Cfam_1.0 Ensembl276,997,822 - 7,036,540 (+)Ensembl
UMICH_Zoey_3.1276,935,774 - 6,973,459 (+)NCBI
UNSW_CanFamBas_1.0276,971,287 - 7,008,847 (+)NCBI
UU_Cfam_GSD_1.02739,626,577 - 39,664,313 (-)NCBI
Hdac7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494567,447,349 - 67,482,511 (+)NCBI
SpeTri2.0NW_0049365125,680,564 - 5,701,182 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDAC7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl578,150,558 - 78,186,072 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1578,150,554 - 78,186,051 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2581,388,011 - 81,393,534 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HDAC7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11144,002,616 - 44,040,766 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1144,003,736 - 44,039,902 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037202,340,868 - 202,378,940 (+)NCBIVero_WHO_p1.0
Hdac7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248164,441,543 - 4,476,520 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D7Rat117  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27128,940,074 - 128,940,200 (+)MAPPERmRatBN7.2
Rnor_6.07139,296,547 - 139,296,672NCBIRnor6.0
Rnor_5.07139,488,296 - 139,488,421UniSTSRnor5.0
RGSC_v3.47136,625,918 - 136,626,043UniSTSRGSC3.4
RGSC_v3.47136,519,124 - 136,519,250RGDRGSC3.4
RGSC_v3.47136,519,125 - 136,519,250UniSTSRGSC3.4
RGSC_v3.47136,625,917 - 136,626,043RGDRGSC3.4
RGSC_v3.17136,702,355 - 136,702,480RGD
RH 3.4 Map71096.1RGD
RH 3.4 Map71096.1UniSTS
RH 2.0 Map7778.4RGD
SHRSP x BN Map786.2099RGD
Cytogenetic Map7q36UniSTS
RH130958  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27128,923,707 - 128,923,900 (+)MAPPERmRatBN7.2
Rnor_6.07139,280,183 - 139,280,375NCBIRnor6.0
Rnor_5.07139,471,765 - 139,471,957UniSTSRnor5.0
RGSC_v3.47136,500,906 - 136,501,098UniSTSRGSC3.4
Celera7125,415,017 - 125,415,209UniSTS
RH 3.4 Map71096.1UniSTS
Cytogenetic Map7q36UniSTS
MARC_6513-6514:996689732:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27128,927,261 - 128,928,046 (+)MAPPERmRatBN7.2
Rnor_6.07139,283,736 - 139,284,520NCBIRnor6.0
Rnor_5.07139,475,318 - 139,476,102UniSTSRnor5.0
RGSC_v3.47136,504,459 - 136,505,243UniSTSRGSC3.4
Celera7125,418,570 - 125,419,354UniSTS
Cytogenetic Map7q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:318
Count of miRNA genes:88
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000011159, ENSRNOT00000011322, ENSRNOT00000071974, ENSRNOT00000072948
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 34 22 6 15 6 63 28 32 11
Low 9 35 35 4 35 8 11 11 7 9 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000092029   ⟹   ENSRNOP00000073744
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7128,923,920 - 128,962,072 (-)Ensembl
Rnor_6.0 Ensembl7139,281,187 - 139,318,455 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094130   ⟹   ENSRNOP00000086506
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7128,923,920 - 128,941,801 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100053   ⟹   ENSRNOP00000096380
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7128,923,920 - 128,942,587 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106809   ⟹   ENSRNOP00000089609
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7128,923,920 - 128,962,072 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118593   ⟹   ENSRNOP00000084448
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7128,923,920 - 128,941,801 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119709   ⟹   ENSRNOP00000080988
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7128,925,137 - 128,944,545 (-)Ensembl
RefSeq Acc Id: XM_006242364   ⟹   XP_006242426
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27128,923,918 - 128,943,938 (-)NCBI
Rnor_6.07139,280,396 - 139,301,009 (-)NCBI
Rnor_5.07139,471,977 - 139,510,581 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242365   ⟹   XP_006242427
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27128,923,918 - 128,943,938 (-)NCBI
Rnor_6.07139,280,396 - 139,301,009 (-)NCBI
Rnor_5.07139,471,977 - 139,510,581 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242366   ⟹   XP_006242428
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27128,923,918 - 128,943,938 (-)NCBI
Rnor_6.07139,280,396 - 139,301,009 (-)NCBI
Rnor_5.07139,471,977 - 139,510,581 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242367   ⟹   XP_006242429
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27128,923,918 - 128,943,938 (-)NCBI
Rnor_6.07139,280,396 - 139,301,009 (-)NCBI
Rnor_5.07139,471,977 - 139,510,581 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765843   ⟹   XP_008764065
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27128,923,918 - 128,962,025 (-)NCBI
Rnor_6.07139,280,396 - 139,319,108 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039080354   ⟹   XP_038936282
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27128,923,918 - 128,957,721 (-)NCBI
RefSeq Acc Id: XM_039080355   ⟹   XP_038936283
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27128,931,714 - 128,943,938 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_006242427   ⟸   XM_006242365
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006242426   ⟸   XM_006242364
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006242429   ⟸   XM_006242367
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006242428   ⟸   XM_006242366
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008764065   ⟸   XM_008765843
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K6B1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073744   ⟸   ENSRNOT00000092029
RefSeq Acc Id: XP_038936282   ⟸   XM_039080354
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038936283   ⟸   XM_039080355
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000096380   ⟸   ENSRNOT00000100053
RefSeq Acc Id: ENSRNOP00000080988   ⟸   ENSRNOT00000119709
RefSeq Acc Id: ENSRNOP00000086506   ⟸   ENSRNOT00000094130
RefSeq Acc Id: ENSRNOP00000084448   ⟸   ENSRNOT00000118593
RefSeq Acc Id: ENSRNOP00000089609   ⟸   ENSRNOT00000106809
Protein Domains
Hist_deacetyl

Protein Structures
Name Modeller Protein Id AA Range Protein Structure Video
AF-Q99P96-F1-model_v2 AlphaFold Q99P96 1-238 view protein structure  

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695631
Promoter ID:EPDNEW_R6142
Type:initiation region
Name:Hdac7_1
Description:histone deacetylase 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07139,318,400 - 139,318,460EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 139298210 139298211 G A snv CDR, COP/CrCrl (MCW & UW), CDS


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 139489959 139489960 G A snv COP/CrCrl (MCW & UW), ZF (KyushuU), DOB/Oda (KyushuU), LE/OrlBarth (UDEL)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619982 AgrOrtholog
BioCyc Gene G2FUF-32175 BioCyc
Ensembl Genes ENSRNOG00000055597 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000073744 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000084448 ENTREZGENE
  ENSRNOP00000086506 ENTREZGENE
  ENSRNOP00000096380 ENTREZGENE
Ensembl Transcript ENSRNOT00000092029 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000094130 ENTREZGENE
  ENSRNOT00000100053 ENTREZGENE
  ENSRNOT00000118593 ENTREZGENE
Gene3D-CATH 3.40.800.20 UniProtKB/TrEMBL
InterPro HDAC4/7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_deacetylse UniProtKB/TrEMBL
  His_deacetylse_dom UniProtKB/TrEMBL
  His_deacetylse_dom_sf UniProtKB/TrEMBL
  Histone_deAcase_II_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ureohydrolase_domain UniProtKB/TrEMBL
NCBI Gene 84582 ENTREZGENE
PANTHER PTHR45364 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45364:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hist_deacetyl UniProtKB/TrEMBL
PhenoGen Hdac7 PhenoGen
PIRSF HDAC_II_euk UniProtKB/TrEMBL
PRINTS HDASUPER UniProtKB/TrEMBL
Superfamily-SCOP SSF52768 UniProtKB/TrEMBL
UniProt A0A0G2K6B1 ENTREZGENE, UniProtKB/TrEMBL
  HDAC7_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-04-14 Hdac7  histone deacetylase 7  Hdac7a  histone deacetylase 7A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Hdac7a  histone deacetylase 7A    histone deacetylase 7  Name updated 1299863 APPROVED
2004-09-10 Hdac7a  histone deacetylase 7  Hdac7    Symbol and Name updated 1299863 APPROVED
2002-08-07 Hdac7  histone deacetylase 7      Symbol and Name status set to provisional 70820 PROVISIONAL