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Gene: Itga5 (integrin subunit alpha 5) Rattus norvegicus
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Symbol: Itga5
Name: integrin subunit alpha 5
Description: Exhibits epidermal growth factor receptor binding activity and integrin binding activity. Involved in several processes, including female pregnancy; integrin-mediated signaling pathway; and positive regulation of cell-substrate adhesion. Localizes to cytoplasm and integrin complex. Predicted to colocalize with cell-cell junction; focal adhesion; and ruffle membrane. Orthologous to human ITGA5 (integrin subunit alpha 5); PARTICIPATES IN integrin mediated signaling pathway; altered integrin mediated signaling pathway; myocardial infarction pathway; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); integrin alpha 5 (mapped); integrin alpha-5; integrin, alpha 5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Itga5_mapped; Itga5_retired
Orthologs:
Homo sapiens (human) : ITGA5 (integrin subunit alpha 5)  HGNC  Alliance
Mus musculus (house mouse) : Itga5 (integrin alpha 5 (fibronectin receptor alpha))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga5 (integrin subunit alpha 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA5 (integrin subunit alpha 5)
Canis lupus familiaris (dog) : ITGA5 (integrin subunit alpha 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga5 (integrin subunit alpha 5)
Sus scrofa (pig) : ITGA5 (integrin subunit alpha 5)
Chlorocebus sabaeus (African green monkey) : ITGA5 (integrin subunit alpha 5)
Heterocephalus glaber (naked mole-rat) : Itga5 (integrin subunit alpha 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07144,970,444 - 144,993,652 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,970,444 - 144,993,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,749,459 - 142,773,323 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,254,256 - 142,277,464 (-)NCBIRGSC3.4rn4RGSC3.4
Celera7130,903,975 - 130,927,190 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itga5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2925
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.