(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of ITGA5 protein CTD PMID:12851778 1,1-dichloroethene increases expression ISO RGD:10817 6480464 vinylidene chloride results in increased expression of ITGA5 mRNA CTD PMID:26682919 1,2-dimethylhydrazine increases expression ISO RGD:10817 6480464 1, 2-Dimethylhydrazine results in increased expression of ITGA5 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate multiple interactions ISO RGD:1351478 6480464 1-Naphthylisothiocyanate results in increased expression of [ITGB6 protein co-treated with ITGA5 protein] more ... CTD PMID:21037076 1-naphthyl isothiocyanate multiple interactions ISO RGD:10817 6480464 [ITGA5 protein co-treated with ITGB6 protein] promotes the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of SMAD2 protein] CTD PMID:21037076 17beta-estradiol multiple interactions ISO RGD:1351478 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of ITGA5 mRNA, [Progesterone co-treated with Estradiol] results in increased expression of ITGA5 mRNA CTD PMID:20226447 , PMID:30165855 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10817 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of ITGA5 mRNA CTD PMID:16214954 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351478 6480464 [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid 2-methyl-4-o-tolylazophenylamide] results in decreased expression of ITGA5 mRNA CTD PMID:29704546 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10817 6480464 Tetrachlorodibenzodioxin results in decreased expression of ITGA5 mRNA CTD PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1351478 6480464 Tetrachlorodibenzodioxin results in increased expression of ITGA5 mRNA CTD PMID:16051281 , PMID:22902829 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ITGA5 mRNA CTD PMID:21215274 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of ITGA5 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of ITGA5 mRNA CTD PMID:21346803 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1351478 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of ITGA5 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ITGA5 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1351478 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of ITGA5 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol increases expression ISO RGD:10817 6480464 bis4-hydroxyphenylsulfone results in increased expression of ITGA5 mRNA CTD PMID:30951980 4-hydroxynon-2-enal decreases expression ISO RGD:1351478 6480464 4-hydroxy-2-nonenal results in decreased expression of ITGA5 mRNA CTD PMID:12419474 4-vinylcyclohexene dioxide affects expression ISO RGD:10817 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of ITGA5 mRNA CTD PMID:20829426 5-aza-2'-deoxycytidine increases expression ISO RGD:10817 6480464 Decitabine results in increased expression of ITGA5 mRNA CTD PMID:27915011 5-aza-2'-deoxycytidine affects expression ISO RGD:1351478 6480464 Decitabine affects the expression of ITGA5 mRNA CTD PMID:23300844 5-bromo-2'-deoxyuridine increases expression ISO RGD:1351478 6480464 Bromodeoxyuridine results in increased expression of ITGA5 mRNA, Bromodeoxyuridine results in increased expression of ITGA5 protein CTD PMID:7519154 5-chloro-7-iodoquinolin-8-ol multiple interactions ISO RGD:1351478 6480464 ITGA5 protein promotes the reaction [[Clioquinol binds to Copper] which results in increased phosphorylation of EGFR protein] CTD PMID:18346929 acetone increases expression ISO RGD:1351478 6480464 Acetone results in increased expression of ITGA5 mRNA CTD PMID:12720008 acetylsalicylic acid decreases expression ISO RGD:1351478 6480464 Aspirin results in decreased expression of ITGA5 mRNA CTD PMID:15928584 aldehydo-D-glucose decreases expression ISO RGD:1351478 6480464 Glucose results in decreased expression of ITGA5 mRNA CTD PMID:31655124 all-trans-retinoic acid multiple interactions ISO RGD:1351478 6480464 Tretinoin promotes the reaction [rosiglitazone results in increased expression of ITGA5 protein] CTD PMID:19467017 all-trans-retinoic acid multiple interactions ISO RGD:10817 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of ITGA5 mRNA CTD PMID:30951980 aluminium oxide multiple interactions ISO RGD:1351478 6480464 [Aluminum Oxide co-treated with Magnesium] results in increased expression of ITGA5 protein CTD PMID:12209937 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of ITGA5 mRNA CTD PMID:30779732 Arg-Gly-Asp multiple interactions ISO RGD:1351478 6480464 arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol binds to [ITGA5 protein binds to ITGB3 protein]] CTD PMID:16790523 aripiprazole multiple interactions ISO RGD:1351478 6480464 [Aripiprazole co-treated with Ozone] results in increased expression of ITGA5 mRNA CTD PMID:31476115 arsane multiple interactions ISO RGD:1351478 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ITGA5 mRNA CTD PMID:32525701 arsenic atom multiple interactions ISO RGD:1351478 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ITGA5 mRNA CTD PMID:32525701 atrazine multiple interactions ISO RGD:1351478 6480464 Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA5 mRNA] CTD PMID:24211529 benomyl decreases expression ISO RGD:1351478 6480464 Benomyl results in decreased expression of ITGA5 mRNA CTD PMID:25530041 benzene increases expression ISO RGD:1351478 6480464 Benzene results in increased expression of ITGA5 mRNA CTD PMID:19162166 benzo[a]pyrene increases expression ISO RGD:10817 6480464 Benzoapyrene results in increased expression of ITGA5 mRNA CTD PMID:22228805 benzo[e]pyrene increases methylation ISO RGD:1351478 6480464 benzoepyrene results in increased methylation of ITGA5 intron CTD PMID:30157460 beta-naphthoflavone decreases expression ISO RGD:1351478 6480464 beta-Naphthoflavone results in decreased expression of ITGA5 mRNA CTD PMID:32858204 bis(2-chloroethyl) sulfide increases expression ISO RGD:10817 6480464 Mustard Gas results in increased expression of ITGA5 mRNA CTD PMID:15674843 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ITGA5 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:1351478 6480464 bisphenol A results in decreased expression of ITGA5 mRNA CTD PMID:31715268 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ITGA5 mRNA CTD PMID:30816183 bisphenol A increases methylation ISO RGD:10817 6480464 bisphenol A results in increased methylation of ITGA5 promoter CTD PMID:27312807 bisphenol A multiple interactions ISO RGD:1351478 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ITGA5 mRNA CTD PMID:28628672 bisphenol A decreases expression ISO RGD:10817 6480464 bisphenol A results in decreased expression of ITGA5 mRNA CTD PMID:25594700 bisphenol F multiple interactions ISO RGD:10817 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of ITGA5 mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:10817 6480464 bisphenol F results in increased expression of ITGA5 mRNA CTD PMID:30951980 bleomycin A5 increases expression ISO RGD:1351478 6480464 bleomycetin results in increased expression of ITGA5 mRNA CTD PMID:21040473 cadmium atom decreases expression ISO RGD:1351478 6480464 Cadmium results in decreased expression of ITGA5 mRNA CTD PMID:20570719 cadmium atom multiple interactions ISO RGD:1351478 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ITGA5 mRNA CTD PMID:29741670 cadmium atom increases expression ISO RGD:1351478 6480464 Cadmium results in increased expression of ITGA5 mRNA CTD PMID:20570719 cadmium dichloride increases expression ISO RGD:1351478 6480464 Cadmium Chloride results in increased expression of ITGA5 protein CTD PMID:28527916 cadmium dichloride multiple interactions ISO RGD:1351478 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ITGA5 mRNA CTD PMID:29741670 cadmium dichloride decreases expression ISO RGD:1351478 6480464 Cadmium Chloride results in decreased expression of ITGA5 mRNA CTD PMID:26472689 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of ITGA5 mRNA CTD PMID:16278290 carbendazim decreases expression ISO RGD:1351478 6480464 carbendazim results in decreased expression of ITGA5 mRNA CTD PMID:25530041 carbon nanotube increases expression ISO RGD:10817 6480464 Nanotubes more ... CTD PMID:25554681 chlorpyrifos decreases expression ISO RGD:10817 6480464 Chlorpyrifos results in decreased expression of ITGA5 mRNA, Chlorpyrifos results in decreased expression of ITGA5 protein CTD PMID:32440878 cisplatin affects expression ISO RGD:1351478 6480464 Cisplatin affects the expression of ITGA5 mRNA CTD PMID:23300844 cobalt dichloride increases expression ISO RGD:1351478 6480464 cobaltous chloride results in increased expression of ITGA5 protein CTD PMID:16798617 copper atom multiple interactions ISO RGD:1351478 6480464 [Chelating Agents binds to Copper] which results in increased expression of ITGA5 mRNA, ITGA5 protein promotes the reaction [[Clioquinol binds to Copper] which results in increased phosphorylation of EGFR protein] CTD PMID:18346929 , PMID:30911355 copper(0) multiple interactions ISO RGD:1351478 6480464 [Chelating Agents binds to Copper] which results in increased expression of ITGA5 mRNA, ITGA5 protein promotes the reaction [[Clioquinol binds to Copper] which results in increased phosphorylation of EGFR protein] CTD PMID:18346929 , PMID:30911355 cortisol increases expression ISO RGD:1351478 6480464 Hydrocortisone results in increased expression of ITGA5 mRNA CTD PMID:21267416 D-glucose decreases expression ISO RGD:1351478 6480464 Glucose results in decreased expression of ITGA5 mRNA CTD PMID:31655124 DDT increases expression ISO RGD:1351478 6480464 DDT results in increased expression of ITGA5 mRNA CTD PMID:22902829 dexamethasone increases expression ISO RGD:10817 6480464 Dexamethasone results in increased expression of ITGA5 mRNA CTD PMID:22733784 dexamethasone multiple interactions ISO RGD:1351478 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of ITGA5 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ITGA5 mRNA CTD PMID:28628672 dextran sulfate multiple interactions ISO RGD:10817 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGA5 mRNA CTD PMID:29950665 diallyl trisulfide decreases expression ISO RGD:1351478 6480464 diallyl trisulfide results in decreased expression of ITGA5 protein CTD PMID:28741790 diazepam increases expression ISO RGD:1351478 6480464 Diazepam results in increased expression of ITGA5 mRNA CTD PMID:19114084 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ITGA5 mRNA CTD PMID:15829613 , PMID:21266533 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of ITGA5 protein CTD PMID:26476374 dioxygen multiple interactions EXP 6480464 Quercetin inhibits the reaction [Oxygen deficiency results in increased expression of ITGA5 protein] CTD PMID:26476374 disodium selenite increases expression ISO RGD:1351478 6480464 Sodium Selenite results in increased expression of ITGA5 mRNA CTD PMID:18175754 doxorubicin decreases expression ISO RGD:1351478 6480464 Doxorubicin results in decreased expression of ITGA5 mRNA CTD PMID:29803840 endosulfan increases expression ISO RGD:1351478 6480464 Endosulfan results in increased expression of ITGA5 mRNA CTD PMID:22902829 ethanol increases expression ISO RGD:1351478 6480464 Ethanol results in increased expression of ITGA5 mRNA CTD PMID:12720008 fenamidone increases expression ISO RGD:10817 6480464 fenamidone results in increased expression of ITGA5 mRNA CTD PMID:27029645 folic acid affects expression ISO RGD:1351478 6480464 Folic Acid affects the expression of ITGA5 mRNA CTD PMID:16361273 furosemide decreases expression EXP 6480464 Furosemide results in decreased expression of ITGA5 mRNA CTD PMID:16526316 genistein increases expression ISO RGD:10817 6480464 Genistein results in increased expression of ITGA5 mRNA CTD PMID:32186404 glucose decreases expression ISO RGD:1351478 6480464 Glucose results in decreased expression of ITGA5 mRNA CTD PMID:31655124 glyphosate decreases expression ISO RGD:1351478 6480464 glyphosate results in decreased expression of ITGA5 mRNA CTD PMID:31295307 heptachlor increases expression ISO RGD:1351478 6480464 Heptachlor results in increased expression of ITGA5 mRNA CTD PMID:22902829 hydrogen peroxide decreases expression ISO RGD:1351478 6480464 Hydrogen Peroxide results in decreased expression of ITGA5 mRNA CTD PMID:12419474 indometacin multiple interactions ISO RGD:1351478 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of ITGA5 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ITGA5 mRNA CTD PMID:28628672 leuprolide multiple interactions ISO RGD:1351478 6480464 Leuprolide inhibits the reaction [IGF1 protein results in increased expression of and affects the localization of [ITGA5 protein binds to ITGB3 protein]] CTD PMID:17143537 lipopolysaccharide multiple interactions ISO RGD:10817 6480464 +-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of ITGA5 mRNA] CTD PMID:25890327 lipopolysaccharide increases expression ISO RGD:10817 6480464 Lipopolysaccharides results in increased expression of ITGA5 mRNA CTD PMID:25890327 LY294002 multiple interactions ISO RGD:1351478 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein results in increased expression of and affects the localization of [ITGA5 protein binds to ITGB3 protein]] CTD PMID:16465378 magnesium atom multiple interactions ISO RGD:1351478 6480464 [Aluminum Oxide co-treated with Magnesium] results in increased expression of ITGA5 protein CTD PMID:12209937 methapyrilene increases methylation ISO RGD:1351478 6480464 Methapyrilene results in increased methylation of ITGA5 intron CTD PMID:30157460 methotrexate increases expression ISO RGD:1351478 6480464 Methotrexate results in increased expression of ITGA5 mRNA CTD PMID:17400583 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of ITGA5 protein CTD PMID:15119844 ozone multiple interactions ISO RGD:1351478 6480464 [Aripiprazole co-treated with Ozone] results in increased expression of ITGA5 mRNA CTD PMID:31476115 ozone increases expression ISO RGD:1351478 6480464 Ozone results in increased expression of ITGA5 mRNA CTD PMID:31476115 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of ITGA5 mRNA CTD PMID:25710175 perfluorononanoic acid increases expression ISO RGD:1351478 6480464 perfluorononanoic acid results in increased expression of ITGA5 mRNA CTD PMID:32588087 perfluorooctanoic acid multiple interactions ISO RGD:1351478 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] results in decreased expression of ITGA5 mRNA CTD PMID:33325755 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1351478 6480464 Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA5 mRNA] CTD PMID:24211529 phorbol 13-acetate 12-myristate increases expression ISO RGD:1351478 6480464 Tetradecanoylphorbol Acetate results in increased expression of ITGA5 mRNA CTD PMID:24211529 phytoestrogen multiple interactions ISO RGD:1351478 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] results in decreased expression of ITGA5 mRNA CTD PMID:33325755 potassium chromate decreases expression ISO RGD:1351478 6480464 potassium chromateVI results in decreased expression of ITGA5 mRNA CTD PMID:22714537 progesterone multiple interactions ISO RGD:1351478 6480464 [Progesterone co-treated with Estradiol] results in increased expression of ITGA5 mRNA CTD PMID:20226447 progesterone increases expression ISO RGD:1351478 6480464 Progesterone results in increased expression of ITGA5 mRNA CTD PMID:20226447 , PMID:21795739 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Oxygen deficiency results in increased expression of ITGA5 protein] CTD PMID:26476374 quercetin increases expression ISO RGD:1351478 6480464 Quercetin results in increased expression of ITGA5 mRNA CTD PMID:30152185 quinoline multiple interactions ISO RGD:1351478 6480464 quinoline analog binds to and results in decreased activity of [ITGA5 protein binds to ITGB3 protein] CTD PMID:16984141 resveratrol multiple interactions ISO RGD:1351478 6480464 [ITGA5 protein binds to ITGB3 protein] promotes the reaction [resveratrol results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:16790523 resveratrol decreases expression ISO RGD:1351478 6480464 resveratrol results in decreased expression of ITGA5 protein CTD PMID:18089832 resveratrol affects binding ISO RGD:1351478 6480464 resveratrol binds to [ITGA5 protein binds to ITGB3 protein] CTD PMID:16790523 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of ITGA5 mRNA CTD PMID:28374803 silicon dioxide increases expression ISO RGD:1351478 6480464 Silicon Dioxide analog results in increased expression of ITGA5 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO RGD:10817 6480464 Silicon Dioxide results in increased expression of ITGA5 mRNA CTD PMID:19073995 sodium arsenate multiple interactions ISO RGD:1351478 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ITGA5 mRNA CTD PMID:32525701 sodium arsenate decreases expression ISO RGD:10817 6480464 sodium arsenate results in decreased expression of ITGA5 mRNA CTD PMID:21795629 sodium arsenite affects methylation ISO RGD:1351478 6480464 sodium arsenite affects the methylation of ITGA5 gene CTD PMID:28589171 sodium fluoride decreases expression ISO RGD:10817 6480464 Sodium Fluoride results in decreased expression of ITGA5 mRNA CTD PMID:27862939 Soman increases expression EXP 6480464 Soman results in increased expression of ITGA5 mRNA CTD PMID:19281266 sunitinib increases expression ISO RGD:1351478 6480464 Sunitinib results in increased expression of ITGA5 mRNA CTD PMID:31533062 tamoxifen decreases expression ISO RGD:10817 6480464 Tamoxifen results in decreased expression of ITGA5 mRNA CTD PMID:25123088 tert-butyl hydroperoxide decreases expression ISO RGD:1351478 6480464 tert-Butylhydroperoxide results in decreased expression of ITGA5 mRNA CTD PMID:12419474 tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of ITGA5 mRNA CTD PMID:22659508 tetracycline increases expression ISO RGD:1351478 6480464 Tetracycline results in increased expression of ITGA5 mRNA CTD PMID:28882639 titanium dioxide increases expression ISO RGD:10817 6480464 titanium dioxide results in increased expression of ITGA5 mRNA CTD PMID:27760801 , PMID:29264374 titanium dioxide multiple interactions ISO RGD:10817 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGA5 mRNA CTD PMID:29950665 titanium dioxide multiple interactions ISO RGD:1351478 6480464 [Vitallium analog binds to titanium dioxide] which results in increased expression of ITGA5 mRNA CTD PMID:23825117 topotecan affects response to substance ISO RGD:1351478 6480464 ITGA5 protein affects the susceptibility to Topotecan CTD PMID:16217747 trichloroethene decreases expression ISO RGD:10817 6480464 Trichloroethylene results in decreased expression of ITGA5 mRNA CTD PMID:28973375 Triptolide increases expression EXP 6480464 triptolide results in increased expression of ITGA5 protein CTD PMID:32519852 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1351478 6480464 tris2-butoxyethyl phosphate affects the expression of ITGA5 mRNA CTD PMID:29024780 troglitazone increases expression ISO RGD:1351478 6480464 troglitazone results in increased expression of ITGA5 mRNA CTD PMID:19140230 urethane increases expression ISO RGD:1351478 6480464 Urethane results in increased expression of ITGA5 mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:1351478 6480464 Valproic Acid results in decreased expression of ITGA5 mRNA CTD PMID:29154799 , PMID:32623605 valproic acid multiple interactions ISO RGD:1351478 6480464 CEBPA protein affects the reaction [Valproic Acid results in decreased expression of ITGA5 mRNA] CTD PMID:32623605 valproic acid increases expression ISO RGD:10817 6480464 Valproic Acid results in increased expression of ITGA5 mRNA CTD PMID:24896083 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of ITGA5 gene CTD PMID:31079544
