Gene: Itga5 (integrin subunit alpha 5) Rattus norvegicus
Analyze
Symbol: Itga5
Name: integrin subunit alpha 5
Description: ENCODES a protein that exhibits cell adhesion molecule binding; epidermal growth factor receptor binding; integrin binding; INVOLVED IN cell adhesion; female pregnancy; integrin-mediated signaling pathway; PARTICIPATES IN integrin mediated signaling pathway; altered integrin mediated signaling pathway; myocardial infarction pathway; ASSOCIATED WITH Hyperalgesia; Gliosis (ortholog); Neoplasm Invasiveness (ortholog); FOUND IN cytoplasm; integrin complex; cell surface (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
AGR Description: Exhibits epidermal growth factor receptor binding activity and integrin binding activity; involved in several processes, including cell adhesion, female pregnancy, and integrin-mediated signaling pathway; localizes to the cytoplasm and integrin complex; predicted to colocalize with the cell-cell junction and ruffle membrane; orthologous to human ITGA5 (integrin subunit alpha 5).
Merged Description: Exhibits epidermal growth factor receptor binding activity and integrin binding activity; involved in several processes, including cell adhesion, female pregnancy, and integrin-mediated signaling pathway; localizes to the cytoplasm and integrin complex; predicted to colocalize with the cell-cell junction and ruffle membrane; orthologous to human ITGA5 (integrin subunit alpha 5); PARTICIPATES IN integrin mediated signaling pathway; altered integrin mediated signaling pathway; myocardial infarction pathway; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); integrin alpha 5 (mapped); integrin alpha-5; integrin, alpha 5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Itga5_mapped; Itga5_retired
Orthologs:
Homo sapiens (human) : ITGA5 (integrin subunit alpha 5)  HGNC  Alliance
Mus musculus (house mouse) : Itga5 (integrin alpha 5 (fibronectin receptor alpha))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga5 (integrin subunit alpha 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA5 (integrin subunit alpha 5)
Canis lupus familiaris (dog) : ITGA5 (integrin subunit alpha 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga5 (integrin subunit alpha 5)
Sus scrofa (pig) : ITGA5 (integrin subunit alpha 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07144,970,444 - 144,993,652 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07142,749,459 - 142,773,323 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,254,256 - 142,277,464 (-)NCBIRGSC3.4rn4RGSC3.4
Celera7130,903,975 - 130,927,190 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Itga5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2925
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.