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Gene: Kcnq3 (potassium voltage-gated channel subfamily Q member 3) Rattus norvegicus
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Symbol: Kcnq3
Name: potassium voltage-gated channel subfamily Q member 3
Description: Exhibits several functions, including calmodulin binding activity; enzyme binding activity; and ion channel binding activity. Involved in cellular response to ammonium ion; nervous system development; and potassium ion transmembrane transport. Localizes to several cellular components, including axon initial segment; membrane raft; and voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KQT-like 3; potassium channel subunit alpha KvLQT3; potassium channel, voltage-gated KQT-like subfamily Q, member 3; potassium voltage-gated channel subfamily KQT member 3; potassium voltage-gated channel, KQT-like subfamily, member 3; potassium voltage-gated channel, subfamily Q, member 3; voltage-gated potassium channel subunit Kv7.3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07106,714,479 - 107,009,639 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7106,717,229 - 107,009,330 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07106,662,621 - 106,956,409 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47103,325,185 - 103,627,045 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17103,359,425 - 103,661,275 (-)NCBI
Celera794,285,105 - 94,579,630 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnq3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69222
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.