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Gene: Lima1 (LIM domain and actin binding 1) Rattus norvegicus
Symbol: Lima1
Name: LIM domain and actin binding 1
RGD ID: 1564050
Description: Predicted to have actin filament binding activity and actin monomer binding activity. Predicted to be involved in several processes, including cholesterol homeostasis; intestinal cholesterol absorption; and negative regulation of actin filament depolymerization. Predicted to localize to several cellular components, including brush border membrane; focal adhesion; and stress fiber. Orthologous to human LIMA1 (LIM domain and actin binding 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epithelial protein lost in neoplasm; eplin; LIM domain and actin-binding protein 1
Homo sapiens (human) : LIMA1 (LIM domain and actin binding 1)  HGNC  Alliance
Mus musculus (house mouse) : Lima1 (LIM domain and actin binding 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lima1 (LIM domain and actin binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMA1 (LIM domain and actin binding 1)
Canis lupus familiaris (dog) : LIMA1 (LIM domain and actin binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lima1 (LIM domain and actin binding 1)
Sus scrofa (pig) : LIMA1 (LIM domain and actin binding 1)
Chlorocebus sabaeus (African green monkey) : LIMA1 (LIM domain and actin binding 1)
Heterocephalus glaber (naked mole-rat) : Lima1 (LIM domain and actin binding 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07141,428,113 - 141,528,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,428,063 - 141,528,397 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,932,904 - 116,035,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,519,353 - 138,617,856 (-)NCBIRGSC3.4rn4RGSC3.4
Celera7127,383,104 - 127,448,452 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Lima1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564050
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.