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Gene: Lima1 (LIM domain and actin binding 1) Rattus norvegicus
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Symbol: Lima1
Name: LIM domain and actin binding 1
Description: Predicted to have actin filament binding activity and actin monomer binding activity. Predicted to be involved in several processes, including cholesterol homeostasis; intestinal cholesterol absorption; and negative regulation of actin filament depolymerization. Predicted to localize to several cellular components, including the brush border membrane; focal adhesion; and stress fiber. Orthologous to human LIMA1 (LIM domain and actin binding 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epithelial protein lost in neoplasm; eplin; LIM domain and actin-binding protein 1
Orthologs:
Homo sapiens (human) : LIMA1 (LIM domain and actin binding 1)  HGNC  Alliance
Mus musculus (house mouse) : Lima1 (LIM domain and actin binding 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lima1 (LIM domain and actin binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMA1 (LIM domain and actin binding 1)
Canis lupus familiaris (dog) : LIMA1 (LIM domain and actin binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lima1 (LIM domain and actin binding 1)
Sus scrofa (pig) : LIMA1 (LIM domain and actin binding 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07141,428,113 - 141,528,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,428,063 - 141,528,397 (-)Ensembl
Rnor_5.0X115,932,904 - 116,035,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,519,353 - 138,617,856 (-)NCBIRGSC3.4rn4RGSC3.4
Celera7127,383,104 - 127,448,452 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Lima1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564050
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.