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Gene: Fam49b (family with sequence similarity 49, member B) Rattus norvegicus
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Symbol: Fam49b
Name: family with sequence similarity 49, member B
Description: Predicted to have MHC class Ib protein binding, via antigen binding activity groove. Predicted to be involved in positive regulation of T cell mediated cytotoxicity; positive regulation of interferon-gamma production; and positive regulation of memory T cell activation. Predicted to localize to the cilium. Orthologous to human FAM49B (family with sequence similarity 49 member B); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PREDICTED
Also known as: hypothetical protein LOC299909; LOC299909; RGD1307697; similar to 0910001A06Rik protein; uncharacterized protein LOC299909
Orthologs:
Homo sapiens (human) : FAM49B (family with sequence similarity 49 member B)  HGNC  Alliance
Mus musculus (house mouse) : Fam49b (family with sequence similarity 49, member B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fam49b (family with sequence similarity 49 member B)
Pan paniscus (bonobo/pygmy chimpanzee) : FAM49B (family with sequence similarity 49 member B)
Canis lupus familiaris (dog) : FAM49B (family with sequence similarity 49 member B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fam49b (family with sequence similarity 49 member B)
Sus scrofa (pig) : FAM49B (family with sequence similarity 49 member B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Celera792,233,570 - 92,357,399 (-)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fam49b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307697
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.