Cyrib (CYFIP related Rac1 interactor B) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Cyrib (CYFIP related Rac1 interactor B) Rattus norvegicus
Analyze
Symbol: Cyrib
Name: CYFIP related Rac1 interactor B
RGD ID: 1307697
Description: Predicted to enable MHC class Ib protein binding, via antigen binding activity groove and small GTPase binding activity. Predicted to be involved in several processes, including positive regulation of interferon-gamma production; positive regulation of memory T cell activation; and regulation of organelle organization. Predicted to be located in cilium and mitochondrion. Orthologous to human CYRIB (CYFIP related Rac1 interactor B); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYFIP-related Rac1 interactor B; Fam49b; family with sequence similarity 49, member B; hypothetical protein LOC299909; LOC299909; RGD1307697; similar to 0910001A06Rik protein; uncharacterized protein LOC299909
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2795,633,876 - 95,760,588 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Celera792,233,570 - 92,357,399 (-)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:12477932   PMID:19056867   PMID:20458337   PMID:22326026   PMID:22522492   PMID:22871113   PMID:23376485   PMID:29059164   PMID:30250061   PMID:31285585  


Genomics

Comparative Map Data
Cyrib
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2795,633,876 - 95,760,588 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Celera792,233,570 - 92,357,399 (-)NCBICelera
Cytogenetic Map7q33NCBI
CYRIB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8129,839,593 - 130,017,129 (-)EnsemblGRCh38hg38GRCh38
GRCh388129,839,593 - 130,017,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378130,851,839 - 131,029,375 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368130,922,898 - 131,021,182 (-)NCBINCBI36hg18NCBI36
Build 348130,922,899 - 131,021,182NCBI
Celera8127,031,822 - 127,130,443 (-)NCBI
Cytogenetic Map8q24.21NCBI
HuRef8126,170,455 - 126,302,342 (-)NCBIHuRef
CHM1_18130,892,084 - 131,069,252 (-)NCBICHM1_1
Cyrib
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391563,800,943 - 63,932,627 (-)NCBIGRCm39mm39
GRCm39 Ensembl1563,800,946 - 63,932,327 (-)Ensembl
GRCm381563,929,094 - 64,060,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1563,929,097 - 64,060,478 (-)EnsemblGRCm38mm10GRCm38
MGSCv371563,760,649 - 63,892,010 (-)NCBIGRCm37mm9NCBIm37
MGSCv361563,758,763 - 63,890,121 (-)NCBImm8
Celera1565,431,654 - 65,563,033 (-)NCBICelera
Cytogenetic Map15D1NCBI
Cyrib
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554614,632,263 - 4,662,016 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554614,634,324 - 4,786,723 (-)NCBIChiLan1.0ChiLan1.0
CYRIB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18129,209,655 - 129,341,048 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8129,209,655 - 129,272,844 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08126,478,020 - 126,653,936 (-)NCBIMhudiblu_PPA_v0panPan3
CYRIB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11326,942,036 - 27,056,547 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1326,942,229 - 27,003,644 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1326,909,797 - 27,057,242 (-)NCBI
ROS_Cfam_1.01327,286,332 - 27,433,998 (-)NCBI
UMICH_Zoey_3.11327,002,963 - 27,150,335 (-)NCBI
UNSW_CanFamBas_1.01327,123,335 - 27,270,680 (-)NCBI
UU_Cfam_GSD_1.01327,423,241 - 27,570,947 (-)NCBI
Cyrib
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530311,268,360 - 11,377,229 (+)NCBI
SpeTri2.0NW_00493647018,665,898 - 18,803,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYRIB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1410,476,137 - 10,643,395 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2410,736,165 - 10,859,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYRIB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18124,308,911 - 124,406,261 (-)NCBI
ChlSab1.1 Ensembl8124,307,049 - 124,345,548 (-)Ensembl
Vero_WHO_p1.0NW_02366603915,634,158 - 15,808,284 (+)NCBI
Cyrib
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473525,752,675 - 25,894,193 (+)NCBI

Position Markers
RH12645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2795,635,771 - 95,635,956 (+)MAPPERmRatBN7.2
Rnor_6.07104,516,462 - 104,516,646NCBIRnor6.0
Rnor_5.0791,519,807 - 91,519,991UniSTSRnor5.0
RGSC_v3.47101,150,553 - 101,150,737UniSTSRGSC3.4
Celera792,233,643 - 92,233,827UniSTS
Cytogenetic Map7q33UniSTS
RH141686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2795,650,786 - 95,650,969 (+)MAPPERmRatBN7.2
Rnor_6.07104,531,927 - 104,532,109NCBIRnor6.0
Rnor_5.0791,535,064 - 91,535,246UniSTSRnor5.0
RGSC_v3.47101,165,579 - 101,165,761UniSTSRGSC3.4
Celera792,247,544 - 92,247,726UniSTS
RH 3.4 Map7661.8UniSTS
Cytogenetic Map7q33UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)72920071124838025Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)712328467106995532Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)748118835128611831Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)750704769128085642Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)751251919118477612Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)751251919145729302Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)751252005111589099Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)755072862123602998Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)755072862123602998Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)755072862123602998Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)761047589113228378Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)768518460113518460Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)769399586111043530Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)769399586111043530Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)770421228115421228Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)771448715145729302Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)777428105127748511Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)777428234122421148Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)781645773140745067Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)785595369130595369Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)785595369130595369Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)788365265119318087Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)788365265121986709Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)788365265133365265Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)788365265134673427Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)791018361136018361Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)791832949145158140Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)791832949145158140Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)793726906138726906Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)793726906138726906Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)796630946141630946Rat
10450828Scl79Serum cholesterol level QTL 793.50.001blood HDL cholesterol amount (VT:0000184)blood low density lipoprotein cholesterol level (CMO:0000053)798200188111043530Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7100028953145729302Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)7100160423140335001Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)7100192194145192194Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)7102588256116249643Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)7103815550126525386Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)7103867802126080176Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 48 32 19 32 8 10 74 35 41 11 8
Low 1 9 9 9 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001126267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC166469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000078116   ⟹   ENSRNOP00000073189
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7104,517,063 - 104,541,392 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090784   ⟹   ENSRNOP00000070286
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)Ensembl
RefSeq Acc Id: NM_001126267   ⟹   NP_001119739
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,635,699 - 95,760,588 (-)NCBI
Rnor_6.07104,516,389 - 104,641,795 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
RGSC_v3.47101,150,480 - 101,275,452 (-)RGD
Celera792,233,570 - 92,357,399 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241633   ⟹   XP_006241695
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,522 (-)NCBI
Rnor_6.07104,514,566 - 104,578,771 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241635   ⟹   XP_006241697
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,499 (-)NCBI
Rnor_6.07104,514,569 - 104,578,752 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765501   ⟹   XP_008763723
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
Rnor_6.07104,514,566 - 104,641,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594751   ⟹   XP_017450240
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
Rnor_6.07104,514,566 - 104,641,874 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078771   ⟹   XP_038934699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
RefSeq Acc Id: XM_039078772   ⟹   XP_038934700
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,726,833 (-)NCBI
RefSeq Acc Id: XM_039078773   ⟹   XP_038934701
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
RefSeq Acc Id: XM_039078774   ⟹   XP_038934702
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,508 (-)NCBI
RefSeq Acc Id: XM_039078775   ⟹   XP_038934703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,573 (-)NCBI
RefSeq Acc Id: XM_039078776   ⟹   XP_038934704
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,494 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001119739   ⟸   NM_001126267
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241695   ⟸   XM_006241633
- Peptide Label: isoform X1
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241697   ⟸   XM_006241635
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008763723   ⟸   XM_008765501
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017450240   ⟸   XM_017594751
- Peptide Label: isoform X1
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070286   ⟸   ENSRNOT00000090784
RefSeq Acc Id: ENSRNOP00000073189   ⟸   ENSRNOT00000078116
RefSeq Acc Id: XP_038934701   ⟸   XM_039078773
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934699   ⟸   XM_039078771
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038934703   ⟸   XM_039078775
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934700   ⟸   XM_039078772
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934702   ⟸   XM_039078774
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934704   ⟸   XM_039078776
- Peptide Label: isoform X4
Protein Domains
DUF1394

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307697 AgrOrtholog
Ensembl Genes ENSRNOG00000061246 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070286 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073189 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078116 UniProtKB/TrEMBL
  ENSRNOT00000090784 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9036548 IMAGE-MGC_LOAD
InterPro DUF1394 UniProtKB/TrEMBL
  FAM49 UniProtKB/TrEMBL
KEGG Report rno:299909 UniProtKB/TrEMBL
MGC_CLONE MGC:187849 IMAGE-MGC_LOAD
NCBI Gene 299909 ENTREZGENE
PANTHER PTHR12422 UniProtKB/TrEMBL
Pfam DUF1394 UniProtKB/TrEMBL
PhenoGen Cyrib PhenoGen
UniProt B2GUZ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Cyrib  CYFIP related Rac1 interactor B  Fam49b  family with sequence similarity 49, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Fam49b  family with sequence similarity 49, member B  RGD1307697_predicted  similar to 0910001A06Rik protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1307697_predicted  similar to 0910001A06Rik protein (predicted)  LOC299909_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299909_predicted  similar to 0910001A06Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL