Cyrib (CYFIP related Rac1 interactor B) - Rat Genome Database

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Gene: Cyrib (CYFIP related Rac1 interactor B) Rattus norvegicus
Analyze
Symbol: Cyrib
Name: CYFIP related Rac1 interactor B
RGD ID: 1307697
Description: Predicted to enable MHC class Ib protein binding, via antigen binding activity groove and small GTPase binding activity. Predicted to be involved in several processes, including positive regulation of memory T cell activation; positive regulation of type II interferon production; and regulation of organelle organization. Predicted to be located in cilium and mitochondrion. Orthologous to human CYRIB (CYFIP related Rac1 interactor B); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CYFIP-related Rac1 interactor B; Fam49b; family with sequence similarity 49, member B; hypothetical protein LOC299909; LOC299909; RGD1307697; similar to 0910001A06Rik protein; uncharacterized protein LOC299909
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2795,633,876 - 95,760,588 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl795,633,876 - 95,697,686 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx797,406,820 - 97,531,642 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0799,608,486 - 99,733,302 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0799,530,454 - 99,655,160 (-)NCBIRnor_WKY
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Celera792,233,570 - 92,357,399 (-)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19056867   PMID:20458337   PMID:22326026   PMID:22522492   PMID:22871113   PMID:23376485   PMID:29059164   PMID:30250061   PMID:31285585  


Genomics

Comparative Map Data
Cyrib
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2795,633,876 - 95,760,588 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl795,633,876 - 95,697,686 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx797,406,820 - 97,531,642 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0799,608,486 - 99,733,302 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0799,530,454 - 99,655,160 (-)NCBIRnor_WKY
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Celera792,233,570 - 92,357,399 (-)NCBICelera
Cytogenetic Map7q33NCBI
CYRIB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388129,839,593 - 130,017,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8129,839,593 - 130,017,504 (-)EnsemblGRCh38hg38GRCh38
GRCh378130,851,839 - 131,029,375 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368130,922,898 - 131,021,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 348130,922,899 - 131,021,182NCBI
Celera8127,031,822 - 127,130,443 (-)NCBICelera
Cytogenetic Map8q24.21NCBI
HuRef8126,170,455 - 126,302,342 (-)NCBIHuRef
CHM1_18130,892,084 - 131,069,252 (-)NCBICHM1_1
T2T-CHM13v2.08130,965,555 - 131,143,607 (-)NCBIT2T-CHM13v2.0
Cyrib
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391563,800,943 - 63,932,627 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1563,800,946 - 63,932,327 (-)EnsemblGRCm39 Ensembl
GRCm381563,929,094 - 64,060,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1563,929,097 - 64,060,478 (-)EnsemblGRCm38mm10GRCm38
MGSCv371563,760,649 - 63,892,010 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361563,758,763 - 63,890,121 (-)NCBIMGSCv36mm8
Celera1565,431,654 - 65,563,033 (-)NCBICelera
Cytogenetic Map15D1NCBI
Cyrib
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554614,632,263 - 4,662,016 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554614,634,324 - 4,786,723 (-)NCBIChiLan1.0ChiLan1.0
CYRIB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18129,209,655 - 129,341,048 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8129,209,655 - 129,272,844 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08126,478,020 - 126,653,936 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CYRIB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11326,942,036 - 27,056,547 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1326,942,229 - 27,003,644 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1326,909,797 - 27,057,242 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01327,286,332 - 27,433,998 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1327,286,332 - 27,432,203 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11327,002,963 - 27,150,335 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01327,123,335 - 27,270,680 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01327,423,241 - 27,570,947 (-)NCBIUU_Cfam_GSD_1.0
Cyrib
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530311,268,360 - 11,377,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647018,721,037 - 18,804,065 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647018,665,898 - 18,803,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYRIB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1410,476,137 - 10,643,395 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2410,736,165 - 10,859,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYRIB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18124,308,911 - 124,406,261 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8124,307,049 - 124,345,548 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603915,634,158 - 15,808,284 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cyrib
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473525,820,175 - 25,894,193 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473525,752,675 - 25,894,193 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cyrib
529 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
10450828Scl79Serum cholesterol level QTL 793.50.001blood HDL cholesterol amount (VT:0000184)blood low density lipoprotein cholesterol level (CMO:0000053)789867376101773158Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)793595647106839474Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat

Markers in Region
RH12645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2795,635,771 - 95,635,956 (+)MAPPERmRatBN7.2
Rnor_6.07104,516,462 - 104,516,646NCBIRnor6.0
Rnor_5.0791,519,807 - 91,519,991UniSTSRnor5.0
RGSC_v3.47101,150,553 - 101,150,737UniSTSRGSC3.4
Celera792,233,643 - 92,233,827UniSTS
Cytogenetic Map7q33UniSTS
RH141686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2795,650,786 - 95,650,969 (+)MAPPERmRatBN7.2
Rnor_6.07104,531,927 - 104,532,109NCBIRnor6.0
Rnor_5.0791,535,064 - 91,535,246UniSTSRnor5.0
RGSC_v3.47101,165,579 - 101,165,761UniSTSRGSC3.4
Celera792,247,544 - 92,247,726UniSTS
RH 3.4 Map7661.8UniSTS
Cytogenetic Map7q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 48 32 19 32 8 10 74 35 41 11 8
Low 1 9 9 9 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001126267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC166469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000078116   ⟹   ENSRNOP00000073189
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl795,640,002 - 95,697,510 (-)Ensembl
Rnor_6.0 Ensembl7104,517,063 - 104,541,392 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090784   ⟹   ENSRNOP00000070286
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl795,633,876 - 95,697,686 (-)Ensembl
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)Ensembl
RefSeq Acc Id: NM_001126267   ⟹   NP_001119739
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,635,699 - 95,760,588 (-)NCBI
Rnor_6.07104,516,389 - 104,641,795 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
RGSC_v3.47101,150,480 - 101,275,452 (-)RGD
Celera792,233,570 - 92,357,399 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241633   ⟹   XP_006241695
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,522 (-)NCBI
Rnor_6.07104,514,566 - 104,578,771 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241635   ⟹   XP_006241697
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,499 (-)NCBI
Rnor_6.07104,514,569 - 104,578,752 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765501   ⟹   XP_008763723
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
Rnor_6.07104,514,566 - 104,641,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594751   ⟹   XP_017450240
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
Rnor_6.07104,514,566 - 104,641,874 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078771   ⟹   XP_038934699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
RefSeq Acc Id: XM_039078772   ⟹   XP_038934700
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,726,833 (-)NCBI
RefSeq Acc Id: XM_039078773   ⟹   XP_038934701
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
RefSeq Acc Id: XM_039078774   ⟹   XP_038934702
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,508 (-)NCBI
RefSeq Acc Id: XM_039078775   ⟹   XP_038934703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,760,573 (-)NCBI
RefSeq Acc Id: XM_039078776   ⟹   XP_038934704
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2795,633,876 - 95,697,494 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001119739   ⟸   NM_001126267
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241695   ⟸   XM_006241633
- Peptide Label: isoform X1
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241697   ⟸   XM_006241635
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JXI6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763723   ⟸   XM_008765501
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JXI6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450240   ⟸   XM_017594751
- Peptide Label: isoform X1
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070286   ⟸   ENSRNOT00000090784
RefSeq Acc Id: ENSRNOP00000073189   ⟸   ENSRNOT00000078116
RefSeq Acc Id: XP_038934701   ⟸   XM_039078773
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934699   ⟸   XM_039078771
- Peptide Label: isoform X1
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934703   ⟸   XM_039078775
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934700   ⟸   XM_039078772
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934702   ⟸   XM_039078774
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934704   ⟸   XM_039078776
- Peptide Label: isoform X4
Protein Domains
CYRIA-B_Rac1-bd

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GUZ9-F1-model_v2 AlphaFold B2GUZ9 1-324 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307697 AgrOrtholog
BioCyc Gene G2FUF-33149 BioCyc
Ensembl Genes ENSRNOG00000061246 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070286 ENTREZGENE
  ENSRNOP00000070286.2 UniProtKB/TrEMBL
  ENSRNOP00000073189 ENTREZGENE
  ENSRNOP00000073189.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078116 ENTREZGENE
  ENSRNOT00000078116.2 UniProtKB/TrEMBL
  ENSRNOT00000090784 ENTREZGENE
  ENSRNOT00000090784.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9036548 IMAGE-MGC_LOAD
InterPro DUF1394 UniProtKB/TrEMBL
  FAM49 UniProtKB/TrEMBL
KEGG Report rno:299909 UniProtKB/TrEMBL
MGC_CLONE MGC:187849 IMAGE-MGC_LOAD
NCBI Gene 299909 ENTREZGENE
PANTHER PTHR12422 UniProtKB/TrEMBL
Pfam DUF1394 UniProtKB/TrEMBL
PhenoGen Cyrib PhenoGen
UniProt A0A0G2JXI6 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K4V6_RAT UniProtKB/TrEMBL
  B2GUZ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Cyrib  CYFIP related Rac1 interactor B  Fam49b  family with sequence similarity 49, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Fam49b  family with sequence similarity 49, member B  RGD1307697_predicted  similar to 0910001A06Rik protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1307697_predicted  similar to 0910001A06Rik protein (predicted)  LOC299909_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299909_predicted  similar to 0910001A06Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL