Wnt10b (Wnt family member 10B) - Rat Genome Database

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Gene: Wnt10b (Wnt family member 10B) Rattus norvegicus
Analyze
Symbol: Wnt10b
Name: Wnt family member 10B
RGD ID: 1304988
Description: Predicted to enable cytokine activity and frizzled binding activity. Involved in cellular response to hydrostatic pressure. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in obesity; split hand-foot malformation 6; and tooth agenesis. Orthologous to human WNT10B (Wnt family member 10B); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 17beta-estradiol 3-benzoate; 3,7-dihydropurine-6-thione; 5-azacytidine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC315294; protein Wnt-10b; wingless related MMTV integration site 10b; wingless-type MMTV integration site family, member 10B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27129,922,088 - 129,927,892 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7129,922,088 - 129,927,892 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7131,729,217 - 131,735,022 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07133,954,768 - 133,960,573 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07133,867,281 - 133,873,087 (-)NCBIRnor_WKY
Rnor_6.07140,448,284 - 140,466,159 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,448,465 - 140,454,268 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X114,958,456 - 114,976,226 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,541,197 - 137,547,000 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17137,617,649 - 137,623,456 (-)NCBI
Celera7126,411,054 - 126,416,855 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-azacytidine  (EXP)
5-formyltetrahydrofolic acid  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diosgenin  (ISO)
dorsomorphin  (ISO)
fenvalerate  (ISO)
genistein  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
linoleic acid  (ISO)
manganese(II) chloride  (EXP)
mercaptopurine  (EXP)
methotrexate  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
O-methyleugenol  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenothrin  (ISO)
purine-6-thiol  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium fluoride  (EXP,ISO)
sotorasib  (ISO)
tamoxifen  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
bone trabecula formation  (ISO)
canonical Wnt signaling pathway  (IBA,ISO)
cell fate commitment  (IBA)
cell population proliferation  (ISO)
cellular response to cAMP  (ISO)
cellular response to hydrostatic pressure  (IEP)
cellular response to organic cyclic compound  (ISO)
cellular response to organic substance  (ISO)
cellular response to parathyroid hormone stimulus  (ISO)
chondrocyte differentiation  (ISO)
epithelial cell differentiation  (ISO)
fat cell differentiation  (ISO)
fungiform papilla development  (ISO)
G2/M transition of mitotic cell cycle  (ISO)
hematopoietic stem cell proliferation  (ISO)
lipid metabolic process  (ISO)
myoblast development  (ISO)
myoblast differentiation involved in skeletal muscle regeneration  (ISO)
negative regulation of cold-induced thermogenesis  (ISO,ISS)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of fat cell differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neuron differentiation  (IBA)
osteoblast differentiation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of bone mineralization  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of epithelial cell differentiation  (ISO)
positive regulation of G2/M transition of mitotic cell cycle  (ISO)
positive regulation of hematopoietic stem cell proliferation  (ISO)
positive regulation of ossification  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of RNA polymerase II transcription preinitiation complex assembly  (ISO)
positive regulation of T cell differentiation  (ISO)
positive regulation of timing of anagen  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
protein stabilization  (ISO)
regulation of cell cycle  (ISO)
regulation of fat cell differentiation  (ISO)
regulation of proteasomal ubiquitin-dependent protein catabolic process  (ISO)
regulation of protein metabolic process  (ISO)
regulation of skeletal muscle tissue development  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
sensory perception of taste  (ISO)
skeletal muscle fiber development  (ISO)
skeletal muscle tissue regeneration  (ISO)
smoothened signaling pathway  (ISO)
T cell differentiation  (ISO)
transcription by RNA polymerase II  (ISO)
Wnt signaling pathway  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats. Aslanidi G, etal., Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E726-36. Epub 2007 Jun 19.
2. WNT10B mutations in human obesity. Christodoulides C, etal., Diabetologia. 2006 Apr;49(4):678-84. Epub 2006 Feb 14.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Hydrostatic pressure promotes Wnt10b and Wnt4 expression dependent and independent on ERK signaling in early-osteoinduced MSCs. Liu J, etal., Biochem Biophys Res Commun. 2009 Feb 6;379(2):505-9. Epub 2008 Dec 30.
6. Wnt10b inhibits development of white and brown adipose tissues. Longo KA, etal., J Biol Chem. 2004 Aug 20;279(34):35503-9. doi: 10.1074/jbc.M402937200. Epub 2004 Jun 9.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. The Wnt Homepage Roel Nusse - Howard Hughes Medical Institute and the Department of Developmental Biology at Stanford University, California, USA
14. Alternative wnt signaling is initiated by distinct receptors. van Amerongen R, etal., Sci Signal. 2008 Sep 2;1(35):re9.
Additional References at PubMed
PMID:9160667   PMID:9769173   PMID:9787155   PMID:10937998   PMID:11092808   PMID:12055200   PMID:15135146   PMID:15673614   PMID:15728361   PMID:17284610   PMID:17708715   PMID:17761539  
PMID:18155657   PMID:19056892   PMID:19723499   PMID:21246616   PMID:30149605   PMID:30779853  


Genomics

Comparative Map Data
Wnt10b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27129,922,088 - 129,927,892 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7129,922,088 - 129,927,892 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7131,729,217 - 131,735,022 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07133,954,768 - 133,960,573 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07133,867,281 - 133,873,087 (-)NCBIRnor_WKY
Rnor_6.07140,448,284 - 140,466,159 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,448,465 - 140,454,268 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X114,958,456 - 114,976,226 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,541,197 - 137,547,000 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17137,617,649 - 137,623,456 (-)NCBI
Celera7126,411,054 - 126,416,855 (-)NCBICelera
Cytogenetic Map7q36NCBI
WNT10B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381248,965,340 - 48,971,735 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1248,965,340 - 48,971,735 (-)EnsemblGRCh38hg38GRCh38
GRCh371249,359,123 - 49,365,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,645,390 - 47,651,810 (-)NCBINCBI36Build 36hg18NCBI36
Build 341247,645,390 - 47,651,810NCBI
Celera1248,153,932 - 48,160,449 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1246,390,715 - 46,397,232 (-)NCBIHuRef
CHM1_11249,324,923 - 49,331,441 (-)NCBICHM1_1
T2T-CHM13v2.01248,927,542 - 48,933,936 (-)NCBIT2T-CHM13v2.0
Wnt10b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,668,593 - 98,676,093 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,668,593 - 98,676,031 (-)EnsemblGRCm39 Ensembl
GRCm381598,770,712 - 98,778,206 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,770,712 - 98,778,150 (-)EnsemblGRCm38mm10GRCm38
MGSCv371598,602,183 - 98,608,581 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361598,599,796 - 98,606,184 (-)NCBIMGSCv36mm8
Celera15100,921,391 - 100,927,785 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.65NCBI
Wnt10b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555007,782,782 - 7,788,309 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555007,782,782 - 7,800,281 (-)NCBIChiLan1.0ChiLan1.0
WNT10B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11240,659,106 - 40,665,734 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,659,106 - 40,665,734 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01239,771,163 - 39,785,411 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
WNT10B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,599,905 - 5,605,506 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,601,089 - 5,605,501 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,652,204 - 40,660,691 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0275,648,026 - 5,656,510 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,650,675 - 5,656,505 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,611,949 - 5,620,434 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,602,160 - 5,610,644 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,044,507 - 41,052,994 (-)NCBIUU_Cfam_GSD_1.0
Wnt10b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,386,524 - 66,396,592 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365126,768,240 - 6,774,172 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365126,768,240 - 6,774,172 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT10B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl514,997,381 - 15,003,567 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1514,997,377 - 15,013,928 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,407,596 - 15,422,005 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WNT10B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,205,728 - 45,229,050 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1145,205,566 - 45,210,893 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037200,931,714 - 200,938,206 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wnt10b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248163,210,828 - 3,227,096 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248163,221,573 - 3,227,102 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wnt10b
15 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:713
Count of miRNA genes:228
Interacting mature miRNAs:274
Transcripts:ENSRNOT00000019505, ENSRNOT00000064417
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
AF029307  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27129,925,514 - 129,925,594 (+)MAPPERmRatBN7.2
Rnor_6.07140,451,891 - 140,451,970NCBIRnor6.0
Rnor_5.0X114,962,035 - 114,962,114UniSTSRnor5.0
RGSC_v3.47137,544,623 - 137,544,702UniSTSRGSC3.4
Celera7126,414,478 - 126,414,557UniSTS
Cytogenetic Map7q36UniSTS
Wnt10b  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27129,923,248 - 129,924,157 (+)MAPPERmRatBN7.2
Rnor_6.07140,449,626 - 140,450,533NCBIRnor6.0
Rnor_5.0X114,959,789 - 114,960,696UniSTSRnor5.0
RGSC_v3.47137,542,358 - 137,543,265UniSTSRGSC3.4
Celera7126,412,215 - 126,413,122UniSTS
Cytogenetic Map7q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 5 2 2 20 5 2
Below cutoff 1 32 21 8 13 8 6 8 46 15 25 10 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000081468   ⟹   ENSRNOP00000073906
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7129,922,088 - 129,927,892 (-)Ensembl
Rnor_6.0 Ensembl7140,448,465 - 140,454,268 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099764   ⟹   ENSRNOP00000094134
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7129,922,088 - 129,927,892 (-)Ensembl
RefSeq Acc Id: NM_001108111   ⟹   NP_001101581
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27129,922,088 - 129,927,892 (-)NCBI
Rnor_6.07140,448,465 - 140,454,268 (-)NCBI
Rnor_5.0X114,958,456 - 114,976,226 (-)NCBI
RGSC_v3.47137,541,197 - 137,547,000 (-)RGD
Celera7126,411,054 - 126,416,855 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101581 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL87035 (Get FASTA)   NCBI Sequence Viewer  
  EDL87036 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001101581   ⟸   NM_001108111
- Peptide Label: precursor
- UniProtKB: A0A0G2K6Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073906   ⟸   ENSRNOT00000081468
RefSeq Acc Id: ENSRNOP00000094134   ⟸   ENSRNOT00000099764

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K6Q8-F1-model_v2 AlphaFold A0A0G2K6Q8 1-389 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304988 AgrOrtholog
BioCyc Gene G2FUF-32115 BioCyc
Ensembl Genes ENSRNOG00000061238 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000073906 ENTREZGENE
  ENSRNOP00000073906.1 UniProtKB/TrEMBL
  ENSRNOP00000094134.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081468 ENTREZGENE
  ENSRNOT00000081468.2 UniProtKB/TrEMBL
  ENSRNOT00000099764.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2460.20 UniProtKB/TrEMBL
InterPro Wnt UniProtKB/TrEMBL
  Wnt10 UniProtKB/TrEMBL
  Wnt_C UniProtKB/TrEMBL
  Wnt_grthfactor_CS UniProtKB/TrEMBL
KEGG Report rno:315294 UniProtKB/TrEMBL
NCBI Gene 315294 ENTREZGENE
PANTHER Wnt UniProtKB/TrEMBL
Pfam wnt UniProtKB/TrEMBL
PhenoGen Wnt10b PhenoGen
PRINTS WNT10PROTEIN UniProtKB/TrEMBL
  WNTPROTEIN UniProtKB/TrEMBL
PROSITE WNT1 UniProtKB/TrEMBL
SMART WNT1 UniProtKB/TrEMBL
UniProt A0A0G2K6Q8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AK95_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-29 Wnt10b  Wnt family member 10B  Wnt10b  wingless-type MMTV integration site family, member 10B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-14 Wnt10b  wingless-type MMTV integration site family, member 10B  Wnt10b  wingless related MMTV integration site 10b   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Wnt10b  wingless related MMTV integration site 10b   Wnt10b_predicted  wingless related MMTV integration site 10b (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Wnt10b_predicted  wingless related MMTV integration site 10b (predicted)      Symbol and Name status set to approved 70820 APPROVED