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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1315980 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GFUS mRNA | CTD | PMID:22206623 | 14-Deoxy-11,12-didehydroandrographolide | decreases expression | ISO | RGD:1315979 | 6480464 | 14-deoxy-11, 12-didehydroandrographolide results in decreased expression of GFUS mRNA | CTD | PMID:22101062 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | RGD:1315979 | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1315980 | 6480464 | Tetrachlorodibenzodioxin affects the expression of GFUS mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GFUS mRNA | CTD | PMID:33387578 | 2,4,6-tribromophenol | decreases expression | ISO | RGD:1315979 | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:1315980 | 6480464 | 3 more ... | CTD | PMID:19467301 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RGD:1315979 | 6480464 | tetrabromobisphenol A results in decreased expression of GFUS protein | CTD | PMID:31675489 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of GFUS mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | RGD:1315979 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GFUS mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of GFUS mRNA | CTD | PMID:32699268 | alpha-pinene | multiple interactions | ISO | RGD:1315979 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GFUS mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of GFUS mRNA | CTD | PMID:32699268 | aristolochic acid A | increases expression | ISO | RGD:1315979 | 6480464 | aristolochic acid I results in increased expression of GFUS protein | CTD | PMID:33212167 | Aroclor 1254 | increases expression | ISO | RGD:1315980 | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of GFUS mRNA | CTD | PMID:23650126 | arsenous acid | multiple interactions | ISO | RGD:1315979 | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GFUS protein] | CTD | PMID:26598702 | atrazine | decreases expression | ISO | RGD:1315979 | 6480464 | Atrazine results in decreased expression of GFUS mRNA | CTD | PMID:22378314 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GFUS mRNA | CTD | PMID:25181051 | Bisphenol B | increases expression | ISO | RGD:1315979 | 6480464 | bisphenol B results in increased expression of GFUS protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | RGD:1315979 | 6480464 | bisphenol F results in increased expression of GFUS protein | CTD | PMID:34186270 | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of GFUS protein | CTD | PMID:28903499 | cadmium dichloride | increases expression | ISO | RGD:1315979 | 6480464 | Cadmium Chloride results in increased expression of GFUS protein | CTD | PMID:24527689 | carbon nanotube | increases expression | ISO | RGD:1315980 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | choline | multiple interactions | ISO | RGD:1315980 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GFUS gene | CTD | PMID:20938992 | cobalt dichloride | decreases expression | ISO | RGD:1315979 | 6480464 | cobaltous chloride results in decreased expression of GFUS mRNA | CTD | PMID:19320972, PMID:19376846 | cyclosporin A | decreases methylation | ISO | RGD:1315979 | 6480464 | Cyclosporine results in decreased methylation of GFUS promoter | CTD | PMID:27989131 | decabromodiphenyl ether | decreases expression | ISO | RGD:1315979 | 6480464 | decabromobiphenyl ether results in decreased expression of GFUS protein | CTD | PMID:31675489 | dextran sulfate | multiple interactions | ISO | RGD:1315980 | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GFUS mRNA | CTD | PMID:29950665 | diarsenic trioxide | multiple interactions | ISO | RGD:1315979 | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GFUS protein] | CTD | PMID:26598702 | diazinon | increases methylation | ISO | RGD:1315979 | 6480464 | Diazinon results in increased methylation of GFUS gene | CTD | PMID:22964155 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of GFUS mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | RGD:1315979 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GFUS mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RGD:1315979 | 6480464 | Doxorubicin results in decreased expression of GFUS mRNA | CTD | PMID:29803840 | elemental selenium | increases expression | ISO | RGD:1315979 | 6480464 | Selenium results in increased expression of GFUS mRNA | CTD | PMID:19244175 | ethyl methanesulfonate | decreases expression | ISO | RGD:1315979 | 6480464 | Ethyl Methanesulfonate results in decreased expression of GFUS mRNA | CTD | PMID:23649840 | fenpyroximate | increases expression | ISO | RGD:1315979 | 6480464 | fenpyroximate results in increased expression of GFUS mRNA | CTD | PMID:33512557 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of GFUS mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | RGD:1315980 | 6480464 | [1 more ... | CTD | PMID:20938992, PMID:22206623 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of GFUS mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | ISO | RGD:1315979 | 6480464 | Ivermectin results in decreased expression of GFUS protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | RGD:1315980 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GFUS gene | CTD | PMID:20938992 | NADP zwitterion | multiple interactions | ISO | RGD:1315979 | 6480464 | NADP binds to and results in increased activity of GFUS protein | CTD | PMID:25526675 | NADP(+) | multiple interactions | ISO | RGD:1315979 | 6480464 | NADP binds to and results in increased activity of GFUS protein | CTD | PMID:25526675 | nickel atom | increases expression | ISO | RGD:1315979 | 6480464 | Nickel results in increased expression of GFUS mRNA | CTD | PMID:25583101 | nickel sulfate | increases expression | ISO | RGD:1315979 | 6480464 | nickel sulfate results in increased expression of GFUS mRNA | CTD | PMID:18651567 | ozone | multiple interactions | ISO | RGD:1315979 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GFUS mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | RGD:1315980 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of GFUS mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | RGD:1315980 | 6480464 | Acetaminophen affects the expression of GFUS mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of GFUS mRNA | CTD | PMID:33387578 | paracetamol | affects response to substance | ISO | RGD:1315979 | 6480464 | GFUS gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | picoxystrobin | increases expression | ISO | RGD:1315979 | 6480464 | picoxystrobin results in increased expression of GFUS mRNA | CTD | PMID:33512557 | potassium chromate | decreases expression | ISO | RGD:1315979 | 6480464 | potassium chromate(VI) results in decreased expression of GFUS mRNA | CTD | PMID:22714537 | pyrimidifen | increases expression | ISO | RGD:1315979 | 6480464 | pyrimidifen results in increased expression of GFUS mRNA | CTD | PMID:33512557 | rotenone | increases expression | ISO | RGD:1315979 | 6480464 | Rotenone results in increased expression of GFUS mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | RGD:1315979 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GFUS mRNA | CTD | PMID:27188386 | selenium atom | increases expression | ISO | RGD:1315979 | 6480464 | Selenium results in increased expression of GFUS mRNA | CTD | PMID:19244175 | sodium arsenite | decreases expression | ISO | RGD:1315979 | 6480464 | sodium arsenite results in decreased expression of GFUS mRNA | CTD | PMID:25879800 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of GFUS protein | CTD | PMID:29459688 | titanium dioxide | multiple interactions | ISO | RGD:1315980 | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GFUS mRNA | CTD | PMID:29950665 | valproic acid | increases methylation | ISO | RGD:1315979 | 6480464 | Valproic Acid results in increased methylation of GFUS gene | CTD | PMID:29154799 | valproic acid | multiple interactions | ISO | RGD:1315979 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GFUS mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RGD:1315979 | 6480464 | Valproic Acid results in increased expression of GFUS mRNA | CTD | PMID:23179753, PMID:26272509 | valproic acid | affects expression | ISO | RGD:1315979 | 6480464 | Valproic Acid affects the expression of GFUS mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | RGD:1315979 | 6480464 | Valproic Acid results in decreased expression of GFUS mRNA | CTD | PMID:29154799 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of GFUS mRNA | CTD | PMID:23034163 | vitamin E | increases expression | ISO | RGD:1315979 | 6480464 | Vitamin E results in increased expression of GFUS mRNA | CTD | PMID:19244175 | |