Nfe2 (nuclear factor, erythroid 2) - Rat Genome Database

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Gene: Nfe2 (nuclear factor, erythroid 2) Rattus norvegicus
Analyze
Symbol: Nfe2
Name: nuclear factor, erythroid 2
RGD ID: 1306888
Description: Predicted to enable several functions, including WW domain binding activity; identical protein binding activity; and protein N-terminus binding activity. Predicted to contribute to cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and negative regulation of syncytium formation by plasma membrane fusion. Predicted to be located in PML body and cytoplasm. Predicted to be part of RNA polymerase II transcription regulator complex and protein-DNA complex. Predicted to be active in nucleus. Orthologous to human NFE2 (nuclear factor, erythroid 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: leucine zipper protein NF-E2; LOC366998; nuclear factor, erythroid derived 2; nuclear factor, erythroid-derived 2 45 kDa subunit; p45 NF-E2; transcription factor NF-E2 45 kDa subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27134,382,758 - 134,395,364 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7134,382,761 - 134,390,108 (-)Ensembl
Rnor_6.07144,872,739 - 144,880,092 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,872,747 - 144,880,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,654,115 - 142,661,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,157,045 - 142,164,122 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17142,237,231 - 142,244,311 (-)NCBI
Celera7130,807,819 - 130,815,170 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
aclacinomycin A  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
anagrelide  (ISO)
apigenin  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (EXP)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
butyric acid  (ISO)
capsaicin  (ISO)
carbon nanotube  (ISO)
catechol  (ISO)
Chebulinic acid  (ISO)
chlorpyrifos  (EXP)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
fipronil  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hemin  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
imidacloprid  (EXP)
leflunomide  (ISO)
luteolin  (EXP)
luteolinidin  (EXP)
methylmercury chloride  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
nitrofen  (EXP)
paracetamol  (EXP)
phenobarbital  (ISO)
phenol  (ISO)
pomalidomide  (ISO)
pravastatin  (EXP,ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
Tellimagrandin I  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (EXP)
tungsten  (ISO)
urethane  (ISO)
XL147  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7995373   PMID:9305852   PMID:11113182   PMID:11863372   PMID:12477932   PMID:12609092   PMID:15005853   PMID:16263792   PMID:21558372   PMID:25007950   PMID:28411267   PMID:29802941  


Genomics

Comparative Map Data
Nfe2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27134,382,758 - 134,395,364 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7134,382,761 - 134,390,108 (-)Ensembl
Rnor_6.07144,872,739 - 144,880,092 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,872,747 - 144,880,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,654,115 - 142,661,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,157,045 - 142,164,122 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17142,237,231 - 142,244,311 (-)NCBI
Celera7130,807,819 - 130,815,170 (-)NCBICelera
Cytogenetic Map7q36NCBI
NFE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381254,292,111 - 54,301,015 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1254,292,111 - 54,301,015 (-)EnsemblGRCh38hg38GRCh38
GRCh371254,685,895 - 54,694,799 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,972,162 - 52,975,811 (-)NCBINCBI36hg18NCBI36
Build 341252,972,164 - 52,975,811NCBI
Celera1254,337,874 - 54,346,770 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1251,725,162 - 51,734,092 (-)NCBIHuRef
CHM1_11254,652,629 - 54,661,558 (-)NCBICHM1_1
T2T-CHM13v2.01254,258,688 - 54,267,591 (-)NCBI
Nfe2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,156,639 - 103,166,830 (-)NCBIGRCm39mm39
GRCm39 Ensembl15103,156,639 - 103,166,830 (-)Ensembl
GRCm3815103,248,212 - 103,258,403 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,248,212 - 103,258,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715103,078,648 - 103,085,847 (-)NCBIGRCm37mm9NCBIm37
MGSCv3615103,076,251 - 103,083,450 (-)NCBImm8
Celera15105,410,760 - 105,417,943 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1558.62NCBI
Nfe2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554581,541,765 - 1,552,323 (-)NCBIChiLan1.0ChiLan1.0
NFE2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11235,168,173 - 35,177,253 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1235,168,173 - 35,177,253 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01234,442,913 - 34,452,016 (+)NCBIMhudiblu_PPA_v0panPan3
NFE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,003,551 - 1,010,514 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,003,816 - 1,010,264 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2745,244,895 - 45,251,871 (-)NCBI
ROS_Cfam_1.0271,000,386 - 1,007,436 (+)NCBI
ROS_Cfam_1.0 Ensembl271,000,659 - 1,007,186 (+)Ensembl
UMICH_Zoey_3.1271,019,396 - 1,028,218 (+)NCBI
UNSW_CanFamBas_1.0271,001,029 - 1,008,045 (+)NCBI
UU_Cfam_GSD_1.02745,648,706 - 45,654,874 (-)NCBI
Nfe2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494561,665,223 - 61,674,841 (+)NCBI
SpeTri2.0NW_00493651211,490,521 - 11,493,655 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFE2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl519,494,677 - 19,501,810 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1519,494,672 - 19,501,810 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2520,353,738 - 20,356,814 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFE2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11150,409,023 - 50,417,931 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1150,408,984 - 50,417,863 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037195,624,075 - 195,633,080 (+)NCBIVero_WHO_p1.0
Nfe2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249042,322,758 - 2,332,194 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249042,324,186 - 2,332,204 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH141475  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,382,781 - 134,382,968 (+)MAPPERmRatBN7.2
Rnor_6.07144,872,764 - 144,872,950NCBIRnor6.0
Rnor_5.07142,654,139 - 142,654,325UniSTSRnor5.0
Celera7130,807,842 - 130,808,028UniSTS
RH 3.4 Map71051.8UniSTS
Cytogenetic Map7q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:134
Count of miRNA genes:120
Interacting mature miRNAs:128
Transcripts:ENSRNOT00000055281
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 12 22 22 11 22 4
Low 1 31 34 19 8 19 1 1 47 32 30 11 1
Below cutoff 2 1 7 10 27 3 7 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000055281   ⟹   ENSRNOP00000052156
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7134,382,761 - 134,390,108 (-)Ensembl
Rnor_6.0 Ensembl7144,872,747 - 144,880,092 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104324   ⟹   ENSRNOP00000088992
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7134,382,761 - 134,386,136 (-)Ensembl
RefSeq Acc Id: NM_001012224   ⟹   NP_001012224
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,382,759 - 134,390,108 (-)NCBI
Rnor_6.07144,872,741 - 144,880,092 (-)NCBI
Rnor_5.07142,654,115 - 142,661,485 (-)NCBI
RGSC_v3.47142,157,045 - 142,164,122 (-)RGD
Celera7130,807,819 - 130,815,170 (-)RGD
Sequence:
RefSeq Acc Id: XM_017595024   ⟹   XP_017450513
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,382,758 - 134,389,819 (-)NCBI
Rnor_6.07144,872,739 - 144,879,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079709   ⟹   XP_038935637
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,382,758 - 134,395,364 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001012224 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450513 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935637 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78925 (Get FASTA)   NCBI Sequence Viewer  
  Q6AYT2 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001012224   ⟸   NM_001012224
- UniProtKB: Q6AYT2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450513   ⟸   XM_017595024
- Peptide Label: isoform X1
- UniProtKB: Q6AYT2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000052156   ⟸   ENSRNOT00000055281
RefSeq Acc Id: XP_038935637   ⟸   XM_039079709
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000088992   ⟸   ENSRNOT00000104324
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYT2-F1-model_v2 AlphaFold Q6AYT2 1-373 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306888 AgrOrtholog
BioCyc Gene G2FUF-31883 BioCyc
Ensembl Genes ENSRNOG00000036837 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000052156 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000088992.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000055281 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000104324.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7106450 IMAGE-MGC_LOAD
InterPro bZIP UniProtKB/Swiss-Prot
  bZIP_Maf UniProtKB/Swiss-Prot
  bZIP_sf UniProtKB/Swiss-Prot
  NF-E2_p45 UniProtKB/Swiss-Prot
  TF_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:366998 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93715 IMAGE-MGC_LOAD
NCBI Gene 366998 ENTREZGENE
PANTHER PTHR24411:SF26 UniProtKB/Swiss-Prot
Pfam bZIP_Maf UniProtKB/Swiss-Prot
PhenoGen Nfe2 PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot
  BZIP_BASIC UniProtKB/Swiss-Prot
SMART BRLZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot
  SSF57959 UniProtKB/Swiss-Prot
UniProt A0A8I6ABT4_RAT UniProtKB/TrEMBL
  NFE2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-07 Nfe2  nuclear factor, erythroid 2  Nfe2  nuclear factor, erythroid derived 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Nfe2  nuclear factor, erythroid derived 2  Nfe2_predicted  nuclear factor, erythroid derived 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Nfe2_predicted  nuclear factor, erythroid derived 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED