Ttll1 (TTL family tubulin polyglutamylase complex subunit L1) - Rat Genome Database

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Gene: Ttll1 (TTL family tubulin polyglutamylase complex subunit L1) Rattus norvegicus
Analyze
Symbol: Ttll1
Name: TTL family tubulin polyglutamylase complex subunit L1
RGD ID: 1309124
Description: Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in sperm axoneme assembly. Predicted to act upstream of or within several processes, including cerebellar Purkinje cell differentiation; mucociliary clearance; and protein polyglutamylation. Predicted to be located in cytoplasm; extracellular region; and motile cilium. Predicted to be active in ciliary basal body and microtubule. Orthologous to human TTLL1 (TTL family tubulin polyglutamylase complex subunit L1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362969; PGs3; polyglutamylase complex subunit TTLL1; probable tubulin polyglutamylase TTLL1; tubulin polyglutamylase complex subunit 3; tubulin polyglutamylase TTLL1; tubulin tyrosine ligase like 1; tubulin tyrosine ligase-like 1; tubulin tyrosine ligase-like family, member 1; tubulin--tyrosine ligase-like protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,499,536 - 116,528,833 (-)NCBIGRCr8
mRatBN7.27114,619,509 - 114,648,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7114,619,508 - 114,648,761 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7116,374,253 - 116,403,529 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07118,599,670 - 118,629,049 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07118,569,144 - 118,598,511 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07124,338,396 - 124,367,719 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,338,395 - 124,367,630 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07124,327,308 - 124,356,639 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,420,125 - 121,441,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7110,932,407 - 110,961,694 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:15890843   PMID:17499049   PMID:19182904   PMID:20442420   PMID:20498047   PMID:29440671   PMID:29593216   PMID:30420556  


Genomics

Comparative Map Data
Ttll1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,499,536 - 116,528,833 (-)NCBIGRCr8
mRatBN7.27114,619,509 - 114,648,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7114,619,508 - 114,648,761 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7116,374,253 - 116,403,529 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07118,599,670 - 118,629,049 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07118,569,144 - 118,598,511 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07124,338,396 - 124,367,719 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,338,395 - 124,367,630 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07124,327,308 - 124,356,639 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,420,125 - 121,441,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7110,932,407 - 110,961,694 (-)NCBICelera
Cytogenetic Map7q34NCBI
TTLL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382243,039,516 - 43,089,391 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2243,039,516 - 43,089,419 (-)EnsemblGRCh38hg38GRCh38
GRCh372243,435,522 - 43,485,397 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,765,589 - 41,815,373 (-)NCBINCBI36Build 36hg18NCBI36
Build 342241,760,142 - 41,809,927NCBI
Celera2227,346,102 - 27,395,837 (-)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2226,394,153 - 26,443,736 (-)NCBIHuRef
CHM1_12243,395,326 - 43,445,000 (-)NCBICHM1_1
T2T-CHM13v2.02243,520,523 - 43,570,587 (-)NCBIT2T-CHM13v2.0
Ttll1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,367,258 - 83,402,675 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,367,970 - 83,395,094 (-)EnsemblGRCm39 Ensembl
GRCm381583,483,057 - 83,518,474 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,483,769 - 83,510,893 (-)EnsemblGRCm38mm10GRCm38
MGSCv371583,314,199 - 83,341,337 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361583,311,538 - 83,338,643 (-)NCBIMGSCv36mm8
Celera1585,617,197 - 85,644,203 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1539.4NCBI
Ttll1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541328,234,486 - 28,250,688 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541328,234,964 - 28,250,899 (-)NCBIChiLan1.0ChiLan1.0
TTLL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22352,864,209 - 52,912,749 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12255,556,957 - 55,605,725 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02223,924,628 - 23,973,282 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12242,128,224 - 42,174,850 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2242,128,224 - 42,174,850 (-)Ensemblpanpan1.1panPan2
TTLL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11022,456,150 - 22,492,375 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1022,456,146 - 22,488,505 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1022,392,648 - 22,439,139 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01023,200,588 - 23,247,276 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1023,200,588 - 23,247,305 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11022,919,827 - 22,966,313 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01023,239,254 - 23,285,573 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01023,413,992 - 23,460,493 (+)NCBIUU_Cfam_GSD_1.0
Ttll1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049456,091,553 - 6,110,264 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936718869,876 - 884,684 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936718869,901 - 884,708 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTLL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl55,793,780 - 5,827,633 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.155,793,760 - 5,827,622 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.253,216,125 - 3,250,371 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTLL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11925,576,525 - 25,616,413 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1925,576,379 - 25,616,328 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604599,827,235 - 99,869,254 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttll1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247525,883,042 - 5,903,687 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247525,883,039 - 5,901,333 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ttll1
143 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:104
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000055978
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
AV014541  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27114,619,815 - 114,619,909 (+)MAPPERmRatBN7.2
Rnor_6.07124,338,703 - 124,338,796NCBIRnor6.0
Rnor_5.07124,327,615 - 124,327,708UniSTSRnor5.0
Celera7110,932,713 - 110,932,806UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001393857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC087669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000055978   ⟹   ENSRNOP00000052832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7114,619,508 - 114,648,761 (-)Ensembl
Rnor_6.0 Ensembl7124,338,395 - 124,367,630 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110361   ⟹   ENSRNOP00000081132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7114,619,765 - 114,648,751 (-)Ensembl
RefSeq Acc Id: NM_001012200   ⟹   NP_001012200
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,537 - 116,528,833 (-)NCBI
mRatBN7.27114,619,510 - 114,648,806 (-)NCBI
Rnor_6.07124,338,397 - 124,367,630 (-)NCBI
Rnor_5.07124,327,308 - 124,356,639 (-)NCBI
RGSC_v3.47121,420,125 - 121,441,444 (+)RGD
Celera7110,932,407 - 110,961,694 (-)RGD
Sequence:
RefSeq Acc Id: NM_001393857   ⟹   NP_001380786
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,537 - 116,528,833 (-)NCBI
mRatBN7.27114,619,510 - 114,648,806 (-)NCBI
RefSeq Acc Id: XM_006242104   ⟹   XP_006242166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,823 (-)NCBI
mRatBN7.27114,619,509 - 114,648,850 (-)NCBI
Rnor_6.07124,338,396 - 124,367,719 (-)NCBI
Rnor_5.07124,327,308 - 124,356,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079601   ⟹   XP_038935529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,824 (-)NCBI
mRatBN7.27114,619,509 - 114,648,850 (-)NCBI
RefSeq Acc Id: XM_063263932   ⟹   XP_063120002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,824 (-)NCBI
RefSeq Acc Id: XM_063263933   ⟹   XP_063120003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,826 (-)NCBI
RefSeq Acc Id: XM_063263934   ⟹   XP_063120004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,823 (-)NCBI
RefSeq Acc Id: XM_063263935   ⟹   XP_063120005
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,528,823 (-)NCBI
RefSeq Acc Id: XM_063263937   ⟹   XP_063120007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,536 - 116,523,800 (-)NCBI
RefSeq Acc Id: XR_010053011
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,910 - 116,528,826 (-)NCBI
RefSeq Acc Id: XR_010053012
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87116,499,910 - 116,528,831 (-)NCBI
RefSeq Acc Id: NP_001012200   ⟸   NM_001012200
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242166   ⟸   XM_006242104
- Peptide Label: isoform X3
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052832   ⟸   ENSRNOT00000055978
RefSeq Acc Id: XP_038935529   ⟸   XM_039079601
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000081132   ⟸   ENSRNOT00000110361
RefSeq Acc Id: NP_001380786   ⟸   NM_001393857
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120003   ⟸   XM_063263933
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063120002   ⟸   XM_063263932
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120005   ⟸   XM_063263935
- Peptide Label: isoform X3
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120004   ⟸   XM_063263934
- Peptide Label: isoform X3
- UniProtKB: Q5PPI9 (UniProtKB/Swiss-Prot),   A0A8I6G7K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120007   ⟸   XM_063263937
- Peptide Label: isoform X4
Protein Domains
TTL

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PPI9-F1-model_v2 AlphaFold Q5PPI9 1-423 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695548
Promoter ID:EPDNEW_R6073
Type:initiation region
Name:Ttll1_1
Description:tubulin tyrosine ligase like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07124,367,645 - 124,367,705EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309124 AgrOrtholog
BioCyc Gene G2FUF-32601 BioCyc
Ensembl Genes ENSRNOG00000010141 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000055978.5 UniProtKB/Swiss-Prot
  ENSRNOT00000110361.1 UniProtKB/TrEMBL
Gene3D-CATH ATP-grasp fold, B domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7316813 IMAGE-MGC_LOAD
InterPro TTL/TTLL_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362969 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105511 IMAGE-MGC_LOAD
NCBI Gene 362969 ENTREZGENE
PANTHER PTHR12241:SF31 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUBULIN POLYGLUTAMYLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TTL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ttll1 PhenoGen
PROSITE TTL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010141 RatGTEx
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6G7K0 ENTREZGENE, UniProtKB/TrEMBL
  Q5PPI9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-12-16 Ttll1  TTL family tubulin polyglutamylase complex subunit L1  Ttll1  tubulin tyrosine ligase like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-25 Ttll1  tubulin tyrosine ligase like 1  Ttll1  tubulin tyrosine ligase-like family, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Ttll1  tubulin tyrosine ligase-like family, member 1  Ttll1  tubulin tyrosine ligase-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ttll1  tubulin tyrosine ligase-like 1  Ttll1_predicted  tubulin tyrosine ligase-like 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ttll1_predicted  tubulin tyrosine ligase-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED